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4781
Inflammatory Acute Response. Biochemical and Cellular Considerations
Published 2015-02-01“…The acute inflammation constitutes a natural, protective-character response that intends to free the organism of the initial cause of the cell lesion and of the consequences that it provokes. …”
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4782
Invariant NKT Cells as Novel Targets for Immunotherapy in Solid Tumors
Published 2012-01-01“…They are uniquely poised to respond rapidly to infection and inflammation and produce cytokines that critically shape the ensuing adaptive cellular response. …”
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4783
Basal Cell Carcinoma Masked in Rhinophyma
Published 2013-01-01“…The anatomical distortion produced by the chronic inflammation and fibrous scarring makes the BCC diagnosis difficult and uncertain. …”
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4784
Anesthetic Management of an Obstetric Patient with Behçet’s Disease Complicated by Transverse Myelitis
Published 2022-01-01“…Transverse myelitis is an acute inflammation of the spinal cord. Its annual incidence is 1–8 per million. …”
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4785
PATHOGENETIC ROLE OF THROMBOCYTES IN THE DEVELOPMENT OF AUTOIMMUNE PATHOLOGY OF THE THYROID GLAND
Published 2018-12-01“…Taking into account the importance of platelets in the mechanisms of inflammation and the autoimmune process, the aim of this study was to experimentally answer a simple question: whether platelets in people with autoimmune euthyroidism, hyperthyroidism and hypothyroidism exhibit the characteristics of high activity. …”
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4786
Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages in Leishmania Infection
Published 2012-01-01“…This ligand-activated nuclear factor curbs inflammation to protect the host from excessive injuries by setting a limit to its destructive force. …”
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4787
Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation
Published 2002-01-01“…The leukotrienes are a family of lipid mediators involved in inflammation and allergy. Leukotriene B4 is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nM concentrations. …”
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4788
Sirtuin activators as an anti-aging intervention for longevity
Published 2025-01-01“…The mammalian sirtuins comprise seven members that have a role in energy metabolism, DNA repair, inflammation, cell survival, apoptosis, cellular senescence, oxidative stress, and mitochondrial production. …”
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4789
Medical Gases: A Novel Strategy for Attenuating Ischemia—Reperfusion Injury in Organ Transplantation?
Published 2012-01-01“…In recent years, inhaled nitric oxide, carbon monoxide, and hydrogen sulfide have been increasingly explored as plausible novel medical gases that can attenuate IRI via multiple mechanisms, including microvascular vasorelaxation, reduced inflammation, and mitochondrial modulation. Here, we review recent advances in research utilizing inhaled nitric oxide, carbon monoxide, and hydrogen sulfide in animal and human studies of IRI and postulate on its future applications specific to solid organ transplantation.…”
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4790
The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis
Published 2011-01-01“…It has been assumed that these structural airway changes have occurred secondary to infection and inflammation, but recent studies suggest that glycosaminoglycan (GAG) remodelling may be an important independent parallel process. …”
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4791
Transplantation of Amniotic Membrane to the Subretinal Space in Pigs
Published 2012-01-01“…AM is well tolerated in the subretinal space, causes only limited inflammation, and is covered with a monolayer of pigmented cells when in contact with the host RPE. …”
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4792
Contemporary Evaluation and Management of the Diabetic Foot
Published 2012-01-01“…Even when properly managed, some of the foot ulcers do not heal and are arrested in a state of chronic inflammation. These wounds can frequently benefit from various adjuvants, such as aggressive debridement, growth factors, bioactive skin equivalents, and negative pressure wound therapy. …”
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4793
PPAR𝜸 and Oxidative Stress: Con(𝜷) Catenating NRF2 and FOXO
Published 2012-01-01“…Peroxisome-proliferator activator receptor γ (PPARγ) is a nuclear receptor of central importance in energy homeostasis and inflammation. Recent experimental pieces of evidence demonstrate that PPARγ is implicated in the oxidative stress response, an imbalance between antithetic prooxidation and antioxidation forces that may lead the cell to apoptotic or necrotic death. …”
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4794
CLINICAL-STATISTICAL STUDY ON THE FREQUENCY OF WISDOM TOOTH INCLUSION PATHOLOGY
Published 2024-12-01“…Including wisdom teeth is a common problem in dental practice, associated with significant complications such as gum inflammation, caries, root resorption of neighboring teeth, and cyst formation. …”
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4795
Cancer Cachexia: Mechanisms and Clinical Implications
Published 2011-01-01“…It involves multiple pathways: procachectic and proinflammatory signals from tumour cells, systemic inflammation in the host, and widespread metabolic changes (increased resting energy expenditure and alterations in metabolism of protein, fat, and carbohydrate). …”
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4796
Mesenchymal Stem Cells and Inflammatory Cardiomyopathy: Cardiac Homing and Beyond
Published 2011-01-01“…This paper gives an overview about how inflammation triggers the functionality of MSCs and how it induces cardiac homing. …”
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4797
Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report
Published 2012-01-01“…Lumbar MRI showed vertebral body height loss and abnormal signal in L1 and L2; vertebral biopsy showed chronic, necrotic, caseating granulomatous inflammation consistent with tuberculous osteomyelitis. …”
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4798
Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients
Published 2025-01-01“…Abstract Background C-reactive protein (CRP) is one of the most commonly monitored inflammatory markers in patients with COVID-19 to gain insight into the inflammation level in the body and to adopt effective disease management and therapeutic strategies. …”
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4799
Mesenchymal stromal cells-derived extracellular vesicles in cartilage regeneration: potential and limitations
Published 2025-01-01“…Recent evidence suggests that the beneficial effects of MSCs are largely mediated by their secreted small extracellular vesicles (sEVs), which have been shown to promote tissue repair and reduce inflammation. MSC-derived sEVs have shown promise in mitigating cartilage degradation and chondrocyte apoptosis, positioning them as a promising alternative to MSC-based therapies for OA treatment. …”
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4800
Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small...
Published 2024-01-01“…Aging and chronic inflammation are related to its pathogenesis. Functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio describe a chronic inflammation and correlate to the survival of older adults with advanced-stage (IIIB-IV) NSCLC. …”
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