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4741
Dr Punctal Polyp, First Case Presentation
Published 2024-06-01“…The stroma was fibrous and showed mild chronic non-specific inflammation composed of lymphocytes and few plasma cells. …”
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4742
Microglial Dysregulation in Psychiatric Disease
Published 2013-01-01“…Microglia, the brain's resident immune cells, are phagocytes of the macrophage lineage that have a key role in responding to inflammation and immune challenge in the brain. More recently, they have been shown to have a number of important roles beyond immune surveillance and response, including synaptic pruning during development and the support of adult neurogenesis. …”
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4743
Disease Specific to Chronic Lymphedema and Class III Obesity
Published 2020-01-01“…It develops due to chronic inflammation and recurrent infection, most commonly on gravity-dependent sites. …”
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4744
Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes
Published 2013-01-01“…Epidermal cells (such as keratinocytes, Langerhans cells, and Merkel cells) express sensor proteins and neuropeptides; these regulate the neuroimmunocutaneous system and participate in nociception and neurogenic inflammation. In the past two decades, there has been widespread use of modalities such as punch skin biopsies, quantitative sensory testing, and laser-evoked potentials to evaluate small caliber nerve fibers. …”
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4745
Use of biologic response modifiers for the management of ocular inflammatory conditions
Published 2018-01-01“…These cases highlight the considerations that are required when clinicians are faced with the need to commence biologic therapy for patients with refractory ocular inflammation.…”
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4746
Granulomatous Osteonecrosis in Crohn’s Disease
Published 2000-01-01“…Review of the pathological sections from the resected hip, however, resulted in detection of granulomatous inflammation with multinucleated giant cells - the histological ’footprint’ of Crohn’s disease in the gastrointestinal tract. …”
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4747
Massive Gastrointestinal Bleeding Related to NSAID Use in a Patient with Ileorectal Anastomosis
Published 2024-01-01“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain and inflammation in over 30 million individuals daily. Gastrointestinal bleeding (GIB) associated with NSAID consumption has been well documented in gastric and duodenal bleeding; however, NSAID-associated GIB distal to the duodenum lacks extensive documentation. …”
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4748
Septic Thrombophlebitis Caused by Fusobacterium necrophorum in an Intravenous Drug User
Published 2013-01-01“…Septic thrombophlebitis is characterized by venous thrombosis, inflammation and bacteremia, that can lead to fatal complications such as sepsis, septic emboli and even death. …”
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4749
The “Target Sign” in a 46-Year-Old Patient with COVID-19 Pneumonia
Published 2021-01-01“…This may be the sequela of focal vascular enlargement, endothelial injury, microangiopathy, and perivascular inflammation. The case described involves a 46-year-old male who presented with subjective fevers, nonproductive cough, and hypoxia, subsequently diagnosed with COVID-19. …”
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4750
Sclerosing Mesenteritis as a Cause of Abdominal Mass and Discomfort in an Elderly Patient: A Case Report and Literature Review
Published 2010-01-01“…Sclerosing mesenteritis is a rare benign process that involves inflammation, fat necrosis, and fibrosis of the mesentery. …”
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4751
What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
Published 2018-01-01“…Probiotics are beneficial to human health and may be an adjunct therapy to increase the eradication rate of HP, lower treatment-associated side effects, and reduce HP-associated gastric inflammation. However, inconsistent test results have prevented conclusions about the therapeutic prowess of probiotics for HP. …”
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4752
Modulation Effects of Curcumin on Erythrocyte Ion-Transporter Activity
Published 2015-01-01“…Curcumin ((1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), the yellow biphenolic pigment isolated from turmeric (Curcuma longa), has various medicinal benefits through antioxidation, anti-inflammation, cardiovascular protection, immunomodulation, enhancing of the apoptotic process, and antiangiogenic property. …”
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4753
The effect of different strains of Helicobacter pylori on platelet aggregation
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4754
Peroxisome proliferator–activated receptor delta and liver diseases
Published 2025-02-01“…PPAR-delta not only regulates physiologic processes of lipid, glucose, and bile acid metabolism but also attenuates pathologic responses to alcohol metabolism, inflammation, fibrosis, and carcinogenesis, and is considered an important therapeutic target in liver diseases. …”
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4755
Peroxisome Proliferator-Activated Receptor β/δ in the Brain: Facts and Hypothesis
Published 2008-01-01“…PPARβ could also regulate central inflammation and antioxidant mechanisms in the damaged brain. …”
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4756
Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy
Published 2025-01-01“…This review delineated the impact of EE on the biological functions associated with NDs, emphasizing its role in enhancing neural plasticity, reducing inflammation, and bolstering cognitive performance. We discussed the molecular underpinnings of the effects of EE, including modulation of key signaling pathways such as extracellular regulated kinase 1/2 (ERK1/2), mitogen-activated protein kinases (MAPK), and AMPK/SIRT1, which were implicated in neuroprotection and synaptic plasticity. …”
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4757
Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes
Published 2022-01-01“…Potential mechanisms of MSC-based intervention on multiple pathological processes of T2DM, such as β-cell exhaustion, hepatic dysfunction, insulin resistance, and systemic inflammation, are also delineated. Moreover, we highlight the importance of understanding the pharmacokinetics (PK) of transplanted cells and discuss the hurdles in MSC-based T2DM therapy toward future clinical applications.…”
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4758
Aneurysm and Neurocysticercosis: Casual or Causal Relationship? Case Report and Review of the Literature
Published 2011-01-01“…At surgery, a viable cysticercus without signs of inflammation or thickened leptomeninges was found in the distal position of the aneurysm. …”
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4759
Application of Low-Intensity Laser in the Treatment of Skeletal Muscle Injury in Runners
Published 2022-01-01“…The experimental results showed that a low-intensity laser can effectively alleviate muscle inflammation, reduce the number of cell damage, bring the mean and integral optical density of protein to the normal level significantly, and reduce the strain degree of exercise muscle. …”
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4760
Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage
Published 2024-12-01“…Through comprehensive analysis of clinical research and experimental results in recent years, it is found that 6-gingerol and 6-shogaol can improve the expression levels of tight junction-related proteins and maintain the integrity and biofunction of the intestinal barrier by inhibiting inflammation, oxidative stress and apoptosis as well as regulating the composition of intestinal microbiota. …”
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