Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent by Murat Tonbul, Mujdat Adas, Taner Bekmezci, Ahmet Duran Kara

“…In this paper, we present a case and the method of our management, in whom host tissue reaction (foreign body granuloma, edema, inflammation, and redness induration) has been observed, as the first and unique adverse effect reported in the literature.…”
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Cutaneous Erythema at Scar Site of Modified Radical Mastectomy: An Unexpected Manifestation of Recurrent Carcinoma by Awrad Mohammed-Reda Nasralla, Mohammed Abdulirazzaq Al-Duhileb, Ali Jamal-Aldein Arini, Samir Sami Amr

“…On follow-up, the wound was healing well, with no signs of inflammation.…”
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Debilitating Manifestation of a Disease with Multiple Names: A Severe Case of Sclerosing Mesenteritis by Valeriia Klymenko, Reba Varughese, Katherine A Woolley, Joseph M Wetherell, Haritha Mopuru, Edward Mensah, Imran Siddiqui

“…We present a case of a 49-year-old male with severe abdominal pain who underwent abdominal biopsy confirming the presence of adipose inflammation and necrosis. The diagnosis of SM was made, and the patient was treated with prednisone and tamoxifen. …”
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The Impact of the Myeloid Response to Radiation Therapy by Michael J. Gough, Kristina Young, Marka Crittenden

“…We discuss how radiation therapy similarly triggers inflammation followed by repair, the consequences to adaptive immune responses in the treatment site, and how the myeloid response to radiation may impact immunotherapies designed to improve control of residual cancer cells.…”
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Colorectal Polyposis and Immune-Based Therapies by Pearl Jacobson-Brown, Manuela G Neuman

“…Nonsteroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors have traditionally been used as inflammation-reducing agents in cases of colon adenoma. …”
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A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer by Xiao Yi Yang, Li Hua Wang, William L. Farrar

“…Since cytokines are not only key modulators of inflammation with pro- and anti-inflammatory functions but they also can either stimulate or inhibit tumor growth and progression, this review summarizes the role for PPARγ in the regulation of cytokine production and cytokine-mediated signal transduction pathways in immune cells and cancer.…”
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The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs by Louis Costanzo, Brian Soto, Richard Meier, Patrick Geraghty

“…The protease and antiprotease imbalance of MMPs and TIMPs are extensively studied in diseases but recent discoveries suggest that TIMPs, specifically, TIMP2 could play other roles in aging and inflammation processes.…”
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Peculiar Presentation of Ulcerative Colitis by Hamdy M. A. Ahmed, Amany Diab, Ayman Ahmed, Samar Abohamad, Hala Elgendy

“…Ulcerative colitis (UC) is a chronic inflammatory and recurrent disorder that is characterized by bowel inflammation. Among the extraintestinal manifestations (EIMs) that associate UC are the joints and renal manifestations. …”
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Pulmonary Arterial Hypertension in Adult-Onset Still’s Disease: Rapid Response to Anakinra by Marc Campos, Elena Schiopu

“…With this case report, we hope to show that anakinra, either by virtue of controlling the overall inflammation in AOSD, or by direct effect on the pulmonary microangiopathy, can improve severe PAH.…”
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A Potential Concept In The Management of Tumors With Modulation of Prostaglandin, Nitric Oxide and Antioxidants by Noori S. Al-Waili

“…Prostaglandins (PGs), nitric oxide (NO), free radicals and chronic inflammation play a major role in tumorogenesis. We have found in vivo that PGs suppress antibody production; reduce serum iron, and modulate bone marrow function. …”
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An Insight into the Sialomes of Bloodsucking Heteroptera by José M. C. Ribeiro, Teresa C. Assumpção, Ivo M. B. Francischetti

“…Saliva of bloodsucking arthropods contains dozens or hundreds of proteins that affect their hosts' mechanisms against blood loss (hemostasis) and inflammation. Because acquisition of the hematophagous habit evolved independently in several arthropod orders and at least twice within the true bugs, there is a convergent evolutionary scenario that creates a different salivary potion for each organism evolving independently to hematophagy. …”
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Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma by Cecilia Ying Ju Sung, Nikki Pui-yue Lee, Hani El-Nezami

“…As may appear to be a new therapeutic target against tumor-promoting inflammation, strategies such as using probiotics to polarize the response away from may be beneficial to slow down tumor progression. …”
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The Future of Asthma Treatment by Louis-Philippe Boulet

“…The recognition of the role of airway inflammation and structural changes in the physiopathology of asthma has led to a re-evaluation of asthma treatment guidelines. …”
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From pathogenesis to new developments in treatment of primary progressive multiple sclerosis. Literature review by A. Juknelytė, Ž. Vaičekauskytė, D. Mickevičienė, R. Balnytė

“…Approximately 15% of all MS cases are manifesting as primary progressive MS (PPMS). Inflammation has long been thought to be the initial factor that starts pathological mechanisms, and neurodegeneration only enhances the progression of the disease. …”
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P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction by Segundo J. Guzman, Zoltan Gerevich

“…The findings discussed here may explain how P2Y1 receptor activation during brain injury, hypoxia, inflammation, schizophrenia, or Alzheimer’s disease leads to an impairment of cognitive processes. …”
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Corrigendum: Recognition of Staphylococcus aureus by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysacc... by Kirstine Mejlstrup Hymøller, Kirstine Mejlstrup Hymøller, Stig Hill Christiansen, Stig Hill Christiansen, Anders Grønnegaard Schlosser, Uffe B. Skov Sørensen, Jean C. Lee, Steffen Thiel, Steffen Thiel

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Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities by Elise K. Brunsgaard, Benjamin Sanchez, Douglas Grossman

“…EID assesses pathological changes to the normal composition and architecture of the skin that influence the flow of electrical current, including changes associated with inflammation, keratinocyte and melanocyte carcinogenesis, and scarring. …”
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Sickle Cell Anemia, the First Molecular Disease: Overview of Molecular Etiology, Pathophysiology, and Therapeutic Approaches by Martin H. Steinberg

“…A multifaceted pathophysiology, triggered by erythrocyte injury induced by the sickle hemoglobin polymer, and encompassing more general cellular and tissue damage caused by hypoxia, oxidant damage, inflammation, abnormal intracellular interactions, and reduced nitric oxide bioavailability, sets off the events recognized clinically as sickle cell disease. …”
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Studies on the Interleukin-10 Gene in Animal Models of Colitis by Hugh J Freeman

“…IL-10-deficient mice develop intestinal inflammation with increased tissue levels of other cytokines, including tumour necrosis factor-alpha. …”
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The Spleen Revisited: An Overview on Magnetic Resonance Imaging by João Palas, António P. Matos, Miguel Ramalho

“…The spleen may be involved in several pathologic conditions like congenital diseases, trauma, inflammation, vascular disorders and hematologic disorders, benign and malignant tumors, and other disease processes that focally or diffusely affect the spleen. …”
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