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4601
A Network Pharmacology-Based Strategy for Unveiling the Mechanisms of Tripterygium Wilfordii Hook F against Diabetic Kidney Disease
Published 2020-01-01“…The key mechanisms of TwHF against DKD might be involved in the reduction of renal inflammation by downregulating VEGFA.…”
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4602
Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis
Published 2025-01-01“…EORA is prone to interstitial lung disease, anemia and high inflammation, and the level of peripheral blood NK cells is higher.…”
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4603
Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury
Published 2025-02-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed a strong correlation between SCI and chronic pain, particularly related to inflammation. Additionally, we examined the relationship between SCI and immune cell infiltration, discovering a significant link between SCI and T cell activation. …”
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4604
<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model
Published 2024-12-01“…Thus, this study supports the use of banana inflorescence in folk medicine and suggests its rational use to develop a phytomedicine to treat pulmonary inflammation.…”
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4605
The Autoimmune Profiles in the Etiopathogenesis of Granulomatous Lobular Mastitis
Published 2025-03-01“…Objectives: Granulomatous lobular mastitis (GLM) is a chronic breast inflammation with low remission and high recurrence. …”
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4606
Antihyperlipidemic and Antiinflammatory Activity of Crude Oil Anguilla Marmorata [Q.] Gaimard in White Rats (Rattus Norvegicus)
Published 2024-03-01“…Blood cholesterol levels were measured and percent inflammation was determined. The results showed that the eel oil extracts led to a decreased of total cholesterol levels 49.60 %, triglycerides 31.15 %, and HDL 14.3 %. …”
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4607
Exploring the role of inflammatory biomarkers in trigeminal neuralgia
Published 2025-02-01“…Background: Trigeminal neuralgia (TN) is a severe facial pain disorder with complex etiology. Inflammation has been suggested as a contributing factor to TN pathogenesis. …”
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4608
Increased pro-SFTPB in HDL promotes the pro-inflammatory transition of HDL and represents a sign of poor prognosis in ARDS patients
Published 2025-01-01“…Abstract Background Acute respiratory distress syndrome (ARDS) is causatively associated with excessive alveolar inflammation involving deregulated pro-inflammatory macrophage polarization. …”
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4609
New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach
Published 2025-02-01“…BackgroundRheumatoid arthritis (RA) is a persistent autoimmune disorder marked by inflammation and joint damage. Although current treatments, such as disease-modifying antirheumatic drugs (DMARDs), help control symptoms, they frequently cause substantial side effects, highlighting the urgent need for safer and more effective alternatives. …”
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4610
Combining O2 High Flow Nasal or Non-Invasive Ventilation with Cooperative Sedation to Avoid Intubation in Early Diffuse Severe Respiratory Distress Syndrome, Especially in Immunoco...
Published 2024-10-01“…COVID), the use of oxygen high flow (HFN) vs. noninvasive ventilation (NIV; conventional vs. helmet) and a multi-modal approach to avoid endotracheal intubation (“intubation”): low normal temperature, cooperative sedation, normalized systemic and microcirculation, anti-inflammation, reduced lung water, upright position, lowered intra-abdominal pressure.…”
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4611
Kyoto International Consensus Report on Anatomy, Pathophysiology and Clinical Significance of the Gastroesophageal Junction
Published 2023-12-01“…The experts reviewed and adopted 28 statements concerning (1) the definition of the gastroesophageal junction (GEJ); (2) the definition of the GEJ zone, covering the area located 1 cm proximal and 1 cm distal in relation to gastroesophageal junction; (3) the assessment of chemical and bacterial (Helicobacter pylori) factors leading to the development of inflammation, metaplasia and neoplasia of the mucosa of the GEJ; and (4) a new definition of Barrett’s esophagus.Conclusion. …”
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4612
The Role of Hypoxia in Orthodontic Tooth Movement
Published 2013-01-01“…Orthodontic forces are known to have various effects on the alveolar process, such as cell deformation, inflammation, and circulatory disturbances. Each of these conditions affecting cell differentiation, cell repair, and cell migration, is driven by numerous molecular and inflammatory mediators. …”
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4613
Exercise-Induced Irisin, the Fat Browning Myokine, as a Potential Anticancer Agent
Published 2019-01-01“…This myokine is usually secreted after exercise by improving energy balance and has shown great potential as a possible treatment for some metabolic diseases such as obesity, insulin resistance, and inflammation. Obesity has been linked to a higher incidence of some cancers. …”
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4614
Neutrophils in Cancer: Two Sides of the Same Coin
Published 2015-01-01“…Neutrophils are the most abundant leukocytes in blood and are considered to be the first line of defense during inflammation and infections. In addition, neutrophils are also found infiltrating many types of tumors. …”
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4615
A Confusing Coincidence: Neonatal Hypoglycemic Seizures and Hyperekplexia
Published 2014-01-01“…Genetic defects in glycine receptors as well as encephalitis, tumors, inflammation, and disgenesis are among the etiologic causes of the disease. …”
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4616
Role of Pore-Forming Toxins in Neonatal Sepsis
Published 2013-01-01“…Pore-forming toxins, however, can also contribute to the induction of inflammation and hence to the manifestation of sepsis. …”
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4617
Type 2 Inflammatory Responses in Autoimmune Demyelination of the Central Nervous System: Recent Advances
Published 2019-01-01“…However, growing evidence suggests that cells and mediators typically associated with type 2 inflammation are involved in several physiopathological conditions, such as defense against toxic substances, anticancer immunity, and autoimmune diseases. …”
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4618
Implant Treatment with 12-Year Follow-Up in a Patient with Severe Chronic Periodontitis: A Case Report and Literature Review
Published 2019-01-01“…Even when the implants are applied, ongoing management of periodontal disease and control of inflammation is necessary to maintain a healthy oral cavity. …”
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4619
Organ-based characterization of B cells in patients with systemic lupus erythematosus
Published 2025-01-01“…Dysregulation of the immune system and disruption of immune tolerance, particularly through the abnormal activation of B lymphocytes and the production of excessive autoantibodies, lead to widespread inflammation and tissue damage, resulting in multi-organ impairment. …”
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4620
Therapeutic Effects of PPARα on Neuronal Death and Microvascular Impairment
Published 2015-01-01“…The PPRE is highly conserved, and PPARs thus regulate transcription of an extensive array of target genes involved in energy metabolism, vascular function, oxidative stress, inflammation, and many other biological processes. PPARα has potent protective effects against neuronal cell death and microvascular impairment, which have been attributed in part to its antioxidant and anti-inflammatory properties. …”
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