Effect of Fluticasone 250 μg/salmeterol 50 μg and Montelukast on Exhaled Nitric Oxide in Asthmatic Patients by Arthur F Gelb, Colleen Flynn Taylor, Chris M Shinar, Carlos A Gutierrez, Noe Zamel

“…BACKGROUND: Monitoring noninvasive biomarkers of inflammation is an important adjunct in asthma therapy.…”
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Simmering Innards: Does Irritable Bowl Syndrome Have an Immunological Basis? by Christopher N Andrews, Eldon A Shaffer

“…Recent studies are identifying a basis for these neural changes - low grade inflammation in the gut - which may play a key role in IBS.…”
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Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…They were also compared in terms of indices of intestinal barrier permeability, inflammation and oxidative stress, brain metabolites as well as composition of the gut microbiota and their metabolites. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…Reducing excess cfDNA may help improve inflammation. Additionally, several trials have demonstrated a correlation between cfDNA concentrations and the activity of rheumatic diseases, indicating the potential of cfDNA, a novel marker for inflammation, in conjunction with C-creative protein (CRP), Erythrocyte Sedimentation Rate (ESR) to monitor disease activity in rheumatic conditions. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Abstract PM2.5-induced inflammation have been demonstrated in the cellular and animal models, but few studies reported the associations of schoolchildren exposure to PM2.5 with their serum inflammatory biomarkers. …”
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Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis by Toni Hospach, Friederike Blankenburg, Anita Heinkele, Kristina Rücklová, Peter Müller‐Abt, Frank Weller‐Heinemann, Laura Buchtala, Jan Maier, Jasmin Kümmerle‐Deschner, Christiane Reiser, Ales Janda, Andreas Urban, Reiner Berendes, Andrea Skrabl‐Baumgartner, Jürgen Brunner, Ralf Trauzeddel, Johannes Peter Haas, Annette Holl‐Wieden, Henner Morbach, Anja Schnabel, Normi Brück, Gabriele Hahn, Wolfgang Emminger, Isabella Valent, Regine Borchers, Christian Klemann, Ilias Tsiflikas, Jens Klotsche, Kirsten Minden, Christian M. Hedrich, Thekla von Kalle

“…When available (3 of 22 patients), histology revealed granulomatous inflammation with lymphocyte infiltration. Development and courses of pCNO did not associate with treatments chosen. …”
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Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy by Wenjun Li, Wenjun Li, Junjiang Sun, Susi Feng, Ariana La Rosa, Panli Zhang, Eveline Y. Wu, Richard Loeser, Chengwen Li, Chengwen Li, Chengwen Li

“…After injection of AAV6/shPD-L1, decreased paw swelling, reduced joint inflammation, and lower levels of pro-inflammatory cytokines in blood were achieved. …”
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Meeting Report on “The International Congress on Autoimmune Pre-disease (2024)” by Justus Ohmes, Afsaneh Mehrpouyan, Julia Wimmer-Groß, Abdul Razzaque Ahmed, Kyle T. Amber, Swayanka Biswas, Angela Christiano, Shirin Emtenani, Stephanie Goletz, Jennifer Elisabeth Hundt, Laura Kirchhoff, Khalaf Kridin, Julie Lasselin, Matthias Laudes, Wing Yu Lee, Ralf J. Ludwig, Sripriya Murthy, Sadegh Mousavi, Tamas Nemeth, Mareike Neumann, Isa Popken, Rochi Saurabh, Alessia Maria Sbaraglia, Jovan Schanzenbacher, Carolin Schmidt, Leon F. Schmidt-Jimènez, Christian Willi Scheiner, Mareile Schlotfeldt, Nora Schoell, Farbod Bahreini, Sarah Stenger

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Initial Presentation of Disseminated Coccidioidomycosis with Ocular Lesions by Edward J. Quinlan, Veenu Gill

“…This highlights the need for physicians to have a heightened suspicion for testing for valley fever in patients living in endemic regions who present with ocular inflammation so that rapid and timely initiation of antifungal therapy may prevent loss of vision.…”
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A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease by Qingdong Guan

“…Inflammatory bowel disease (IBD) is a chronic and life-threating inflammatory disease of gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis of IBD is complex. Recent studies have greatly improved our knowledge of the pathophysiology of IBD, leading to great advances in the treatment as well as diagnosis of IBD. …”
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WOUND AND ITS HEALING: A CONCISE PHYSIOLOGICAL REVIEW by Syeda Yamna Zia et al

“…Generally, wounds are healed by four phasestermed as vascularization, inflammation, proliferation, and maturation. A number of factors such as age, weight, nutritional status, immune response, dehydration, inadequate blood supply to the wound, chronic disease, radiations, surgery etc. greatly influence the process of wound healing …”
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Mycophenolate Mofetil for the Treatment of Autoimmune Hepatitis in Patients Refractory or Intolerant to Conventional Therapy by Kaveh Sharzehi, Mary Ann Huang, Ian R Schreibman, Kimberly A Brown

“…BACKGROUND: Autoimmune hepatitis is characterized by hepatocellular inflammation often progressing to cirrhosis. Standard treatment consists of corticosteroids and azathioprine. …”
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Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation by Anne Bugge, Susanne Mandrup

“…The peroxisome proliferator-activated receptors (PPARs) are central regulators of fat metabolism, energy homeostasis, proliferation, and inflammation. The three PPAR subtypes, PPAR𝛼, 𝛽/𝛿, and 𝛾 activate overlapping but also very different target gene programs. …”
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Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin by Xiaoyu Chen, Hongyuan Zhao, Fanqiang Meng, Libang Zhou, Zhaoxin Lu, Yingjian Lu

“…The gut microbiota appeared to be important in controlling glucose metabolism, IR, fat accumulation, inflammation and antioxidation, according to Spearman’s correlation coefficients. …”
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SALIVARY SPECIFIC IgE TO D1 AND G6 IN PATIENTS WITH RHINITIS WITH OR WITHOUT S. AUREUS COLONIZATION by Diana Hristova, Antoaneta Decheva, Deyan Donchev, Damyan Vangelov, Vancho Donev, Georgi Nikolov, Maria Nikolova

“…As superantigens, Ses generate intense Th2 inflammation, with 70-80% of IgE being locally synthesized. …”
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P2Y2 Receptor Mediated Neuronal Regeneration and Angiogenesis to Affect Functional Recovery in Rats with Spinal Cord Injury by Ruidong Cheng, Genying Zhu, Chengtao Ni, Rui Wang, Peng Sun, Liang Tian, Li Zhang, Jie Zhang, Xiangming Ye, Benyan Luo

“…The P2Y2R inhibitor relieved neuronal inflammation after SCI. Compared with the sham group, the apoptotic rate of spinal cord tissue cells in the model group was significantly increased. …”
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miR-181a-5p Inhibits Pyroptosis in Sepsis-Induced Acute Kidney Injury through Downregulation of NEK7 by Meng Zhang, Deyuan Zhi, Jin Lin, Pei Liu, Yajun Wang, Meili Duan

“…Pyroptosis of HK-2 cells promotes inflammation. miR-181a-5p inhibits pyroptosis through downregulation of NEK7 in LPS-induced HK-2 cells and CLP-induced mice. …”
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Enhanced precise therapy of ROS-sensitive dual-layer shell nanoparticles loading quercetin on DSS-induced ulcerative colitis mice by Yang Bai, Danling Jiang, Boda Wu, Jiao Peng, Ji Wang, Yuhui Chen, Xi Li

“…As one of the traditional Chinese medicine treatments for UC, quercetin has received attention because it can attenuate inflammation. However, oral administration of quercetin does not perform well in colitis therapy. …”
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Cancer-associated fibroblasts and their role in tumor progression by M. S. Ermakov, A. A. Nushtaeva, V. A. Richter, O. A. Koval

“…The molecular phenotype of activated CAFs is similar to fibroblasts activated during inflammation. In activated CAFs, alpha-smooth muscle actin (α-SMA) is synthetized de novo and various proteases and fibronectin are produced. …”
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Bifunctional copper ion/melittin incorporated hydrogel with antimicrobial and antioxidant capabilities for infected skin wound healing by Jun Yao, Xiao Li, Minjie Lin, Zhuoqi Han, Xiaonan Wang, Jingjing Guo, Bing Wu, Jiajie Xia

“…Skin infections present a major clinical challenge, as bacterial invasion and inflammation can complicate wound healing. Therefore, bacterial infections must be treated while the accompanying inflammation and oxidative stress are regulated. …”
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