Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? by Elif Kaya Çelik, Fatih Öner

“…Abstract Background Since monocytes secrete cytokines, high monocyte counts may indicate subclinical inflammation. HDL-C, a significant component of total cholesterol, may reduce inflammation. …”
Get full text

The Diagnostic and Predictive Significance of Immune-Related Genes and Immune Characteristics in the Occurrence and Progression of IgA Nephropathy by Jian-Bo Qing, Wen-Zhu Song, Chang-Qun Li, Ya-Feng Li

“…Finally, ssGSEA analysis was performed on the GSE141295 dataset to discover the abnormal inflammation in IgAN. Results. Machine learning (ML) performed excellently in diagnosing IgAN using six DIRGs. …”
Get full text

The link between spreading depolarization and innate immunity in the central nervous system by Kadir Oguzhan Soylu, Muge Yemisci, Hulya Karatas

“…Inflammation extends beyond the central nervous system to peripheral structures, including the meninges and trigeminovascular system, which are critical for headache initiation. …”
Get full text

Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice by Jie Yan, Si-Chi Xu, Chun-Yan Kong, Xiao-Yang Zhou, Zhou-Yan Bian, Ling Yan, Qi-Zhu Tang

“…Oxidative stress, inflammation and cardiac apoptosis were closely involved in doxorubicin (DOX)-induced cardiac injury. …”
Get full text

Amelioration of metabolic disorders by a mushroom-derived polyphenols correlates with the reduction of Ruminococcaceae in gut of DIO mice by Li Sun, Li Bao, Dorji Phurbu, Shanshan Qiao, Shanshan Sun, Yangzom Perma, Hongwei Liu

“…Oral administration of PAE reduced hyperglycemia, hyperlipidemia, hepatic steatosis, and LPS-related inflammation in high fat diet-induced obese (DIO) mice. …”
Get full text

Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future by S. Gitto, G. Vitale, E. Villa, P. Andreone

“…The first-line pharmacological choices are vitamin E and pioglitazone, both showing a positive effect on transaminases, fat accumulation, and inflammation. Nevertheless, vitamin E has no proven effect on fibrosis and on long-term morbidity and mortality and pioglitazone has a negative impact on weight. …”
Get full text

Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population by Mohsen Mazidi, Hong-kai Gao, Andre Pascal Kengne

“…The relationship between serum trans-fatty acids (TFAs) and systemic inflammation markers is unclear. We investigated the association of serum TFAs with high sensitivity C-reactive protein (hs-CRP) and fibrinogen in adult Americans. …”
Get full text

Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

“…In solid organ transplantation, ischemia/reperfusion (IR) injury during organ procurement, storage and reperfusion is an unavoidable detrimental event for the graft, as it amplifies graft inflammation and rejection. Intracellular mitogen-activated protein kinase (MAPK) signaling pathways regulate inflammation and cell survival during IR injury. …”
Get full text

Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology by Jinke Huang, Yijun Zheng, Jinxin Ma, Jing Ma, Mengxiong Lu, Xiangxue Ma, Fengyun Wang, Xudong Tang

“…The mechanisms of action of WMP involve anti-inflammation, antioxidation, and modulation of immunity, which provides evidence for the therapeutic role of WMP in UC.…”
Get full text

VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis by Genxiang Rong, Zhenyu Zhang, Wenjing Zhan, Minnan Chen, Jingjing Ruan, Cailiang Shen

“…These loci were closely related to abnormal proliferation, inflammation, and angiogenesis in the synovial tissues of patients with OA. …”
Get full text

Features of the course and treatment of low back pain in patients with reduced bone mineral density by N. M. Shuba, T. S. Tsymbaliuk, A. S. Krylova, T. D. Voronova

“…Levels of nonspecific indicators of inflammation (ESR and CRP), cytokines (IL-1, IGF-1, NO), metabolic indicators (lipid, carbohydrate, liver markers) were also studied. …”
Get full text

Effect of Uncaria rhynchophylla against Thioacetamide-Induced Acute Liver Injury in Rat by Mi-Rae Shin, Min Ju Kim, Jin A Lee, Seong-Soo Roh

“…Both oxidative stress (OS) and inflammation are two fundamental pathological processes of acute liver injury (ALI). …”
Get full text

Interplay between Extracellular Matrix and Neutrophils in Diseases by Yanyan Zhu, Yumeng Huang, Qian Ji, Shengqiao Fu, Jia Gu, Ningzheng Tai, Xu Wang

“…Neutrophils are the most abundant immune cells in circulation and play key roles in orchestrating a complex series of events during inflammation. Neutrophils can also mediate ECM remodeling by providing specific matrix-remodeling enzymes (such as neutrophil elastase and metalloproteinases), generating neutrophil extracellular traps, and releasing exosomes. …”
Get full text

Proteomic Analysis of Saliva Identifies Potential Biomarkers for Orthodontic Tooth Movement by Mohd Faiz Ellias, Shahrul Hisham Zainal Ariffin, Saiful Anuar Karsani, Mariati Abdul Rahman, Shahidan Senafi, Rohaya Megat Abdul Wahab

“…Orthodontic treatment has been shown to induce inflammation, followed by bone remodelling in the periodontium. …”
Get full text

Features of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry by Charlotte Förster, André Eichert, Dominik Oberthür, Christian Betzel, Reinhard Geßner, Andreas Nitsche, Jens P. Fürste

Get full text

The Anti-Inflammatory, Phytoestrogenic, and Antioxidative Role of Labisia pumila in Prevention of Postmenopausal Osteoporosis by M. E. Nadia, A. S. Nazrun, M. Norazlina, N. M. Isa, M. Norliza, S. Ima Nirwana

“…Osteoporosis is characterized by skeletal degeneration with low bone mass and destruction of microarchitecture of bone tissue which is attributed to various factors including inflammation. Women are more likely to develop osteoporosis than men due to reduction in estrogen during menopause which leads to decline in bone-formation and increase in bone-resorption activity. …”
Get full text

Growth Characteristics of Sheep-Derived <i>Bacteroides fragilis</i> and Preliminary Research on Effects in Mice and Lambs by Cheng Cheng, Jinye Du, Jianping Tao, Darong Cheng

“…Therefore, <i>Bacteroides fragilis</i> exhibited remarkable effects in regulating intestinal homeostasis, alleviating inflammation, and promoting recovery from diarrhea.…”
Get full text

Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation by Yi Shen, Changli Lu, Ruoting Men, Jianping Liu, Tinghong Ye, Li Yang

“…Histologically, the primary manifestation of A-AIH was lobular inflammation, which was usually accompanied by lobular central necrosis. …”
Get full text

Immediate Free Jejunum Transfer for Salvage Surgery of Gastric Tube Necrosis by Hiroki Umezawa, Takeshi Matsutani, Rei Ogawa, Hiko Hyakusoku

“…The one-step procedure may be particularly useful in cases where the inflammation is discovered early.…”
Get full text

Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice by Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein

“…Unexpectedly, ACKR2 deletion reduced renal inflammation in diabetes and the ultimate response was a high degree of protection from diabetic nephropathy.…”
Get full text