Quantification of Eosinophilic Granule Protein Deposition in Biopsies of Inflammatory Skin Diseases by Automated Image Analysis of Highly Sensitive Immunostaining by Peter Kiehl, Katrin Falkenberg, Markus Vogelbruch, Alexander Kapp

“…Eosinophilic granulocytes are major effector cells in inflammation. Extracellular deposition of toxic eosinophilic granule proteins (EGPs), but not the presence of intact eosinophils, is crucial for their functional effect in situ. …”
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Regulation of Neutrophil Survival/Apoptosis by Mcl-1 by Eric Milot, János G. Filep

“…The short-lived prosurvival Bcl-2 family protein, Mcl-1 (myeloid cell leukemia-1), is instrumental in controlling apoptosis and consequently neutrophil lifespan in response to rapidly changing environmental cues during inflammation. This paper will focus on multiple levels of control of Mcl-1 expression and function and will discuss targeting Mcl-1 as a potential therapeutic strategy to enhance the resolution of inflammation through accelerating neutrophil apoptosis.…”
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Contemporary treatment of right ventricular failure by Bibhuti B. Das, MD, Shashi Raj, MD, FAAP, FACC

“…The pathophysiology of RVF involves complex interactions, such as maladaptive hypertrophy, metabolic reprogramming, inflammation, fibrosis, apoptosis, and endothelial dysfunction. …”
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Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets by Lingmin Shao, Xingping Qin, Jia Liu, Zhihong Jian, Xiaoxing Xiong, Renzhong Liu

“…It is well accepted that sustained chronic inflammation plays a crucial role in the pathology of cerebral aneurysms. …”
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Virus Infection-Induced Bronchial Asthma Exacerbation by Mutsuo Yamaya

“…Infection with respiratory viruses, including rhinoviruses, influenza virus, and respiratory syncytial virus, exacerbates asthma, which is associated with processes such as airway inflammation, airway hyperresponsiveness, and mucus hypersecretion. …”
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A Case of Cerebral Vasculitis Associated with Ulcerative Colitis by Naveen Raj, Matthew Arkebauer, Barry Waters, Brucha Dickinson

“…Ulcerative colitis (UC) is a chronic, debilitating condition characterized by inflammation of the colonic mucosa. It is regarded as a systemic inflammatory disorder that can affect a number of organ systems. …”
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A Case of Xanthogranulomatous Pyelonephritis Associated with Renoduodenal Fistula by R. Conor Holton-Burke, Mini Varughese

“…Xanthogranulomatous pyelonephritis (XGP) is a rare form of pyelonephritis associated with repeated infection, chronic inflammation, and obstruction. Various fistulas, including those to the intestine, are a known association with XGP. …”
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“A Dangerous Black Box:” Idiopathic Hemophagocytic Lymphohistiocytosis in Adult Patients—A Case Report and Review of the Literature by Nada Agbariah, Javier Sanz, Alicia Rovó

“…Hemophagocytic lymphohistiocytosis (HLH) is a rare potentially life-threatening condition characterized by aberrant inflammation that can be related to genetic or sporadic forms. …”
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Orientin and vitexin attenuate lipopolysaccharide-induced inflammatory responses in RAW264.7 cells: a molecular docking study, biochemical characterization, and mechanism analysis by Yue Yu, Fusheng Pei, Zhanming Li

“…Moreover, RAW264.7 cells with lipopolysaccharide-induced inflammation were used to evaluate the anti-inflammatory activities of orientin and vitexin, based on the inflammation-related cytokines production, quantitative real-time reverse transcription PCR, and western blotting analysis. …”
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Biomechanics in the onset and severity of spondyloarthritis: a force to be reckoned with by Mark Hwang, Priyanka Iyer, Lauren Ridley, Michael M Weisman

“…Furthermore, we know that damage and inflammation can limit spinal mobility, but is there a cycle created by altered spinal mobility leading to additional damage and inflammation?…”
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Leukocyte Adhesion Molecules in Diabetic Retinopathy by Kousuke Noda, Shintaro Nakao, Susumu Ishida, Tatsuro Ishibashi

“…The mechanisms underlying the development of DR are not fully understood; however, extensive studies have recently implicated chronic, low-grade inflammation in the pathophysiology of DR. During inflammation leukocytes undergo sequential adhesive interactions with endothelial cells to migrate into the inflamed tissues, a process known as the “leukocyte recruitment cascade” which is orchestrated by precise adhesion molecule expression on the cell surface of leukocytes and the endothelium. …”
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Non-Alcoholic Fatty Liver Disease, Bile Acids and Intestinal Microbiota by R. V. Maslennikov, Yu. V. Evsyutina

“…In the course of NAFLD, a change in the composition of the intestinal microbiota is observed, which contributes to the development of inflammation in the liver and disrupts the metabolism of bile acids, leading to insulin resistance.…”
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Radionuclide Small Intestine Imaging by Jiri Dolezal, Marcela Kopacova

“…Nuclear medicine has a few methods—scintigraphy with red blood cells labelled by means of Tc99m for detection of the source of bleeding in the small intestine, Meckel’s diverticulum scintigraphy for detection of the ectopic gastric mucosa, radionuclide somatostatin receptor imaging for carcinoid, and radionuclide inflammation imaging. Video capsule or deep enteroscopy is the method of choice for detection of most lesions in the small intestine. …”
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PEMANFAATAN DAN BIOAKTIVITAS SIDAGURI (Sida rhombifolia) by Marina Silalahi

“…In ethnobotany SR used as traditional medicine include gout, broken bones, wounds, fever, treatment of diarrhea, malaria, gastrointestinal dysentery, fever, asthma, and inflammation and anti-inflammation. SR has bioactivity as an anti-inflammatory, anti-microbial, antioxidant, anti-cancer, drug for kidney disorders, hepatoprotective, anti-diabetes mellitus, and analgesics. …”
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Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model by Ngoc Buu Tran, Sook-Jeong Lee

“…Abstract Chronic inflammatory pain is often caused by peripheral tissue damage and persistent inflammation. This disease substantially affects patients’ physical and social well-being. …”
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Stress in Obesity and Associated Metabolic and Cardiovascular Disorders by Paul Holvoet

“…Finally, we discuss the limitations of current anti-inflammation and antioxidant therapy to treat obesity.…”
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Advances in Research Related to MicroRNA for Diabetic Retinopathy by Yahan Luo, Chunxia Li

“…MicroRNAs have been shown to play a significant role in DR, particularly in the molecular mechanisms of inflammation, oxidative stress, and neurodegeneration. …”
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The Clinical Significance of Exhaled Nitric Oxide in Asthma by Sachin Pendharkar, Sanjay Mehta

“…There is no simple, noninvasive technique for the assessment of severity of actual airway inflammation in asthma. The collection and analysis of nitric oxide (NO) levels in exhaled breath has recently become feasible in humans. …”
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Diagnostic performance of optical spectral transmission compared to magnetic resonance imaging in patients with inflammatory arthritis by Konstantinos Triantafyllias, Mohammed Alhaddad, Andreas Schwarting, Veronika Balaklytska, Xenofon Baraliakos

“…Aim of this study was therefore to investigate the performance of OST in assessing joint inflammation as compared to MRI in patients with inflammatory arthritis (IA). …”
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Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue by Jieun Shin, Kavita B. Hosur, Kalyani Pyaram, Ravi Jotwani, Shuang Liang, Triantafyllos Chavakis, George Hajishengallis

“…The reciprocal regulation between Del-1 and inflammation may contribute to optimally balance the protective and the potentially harmful effects of inflammatory cell recruitment.…”
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