Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pil... by Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz

“…To reflect periodontal inflammation, the periodontal inflamed surface area (PISA) was applied. …”
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Additive Effects of Glutathione in Improving Antibiotic Efficacy in HIV–<i>M.tb</i> Co-Infection in the Central Nervous System: A Systematic Review by Leena Nabipur, Michael Mouawad, Vishwanath Venketaraman

“…Current treatments face challenges such as drug resistance, immune reconstitution inflammatory syndrome (IRIS), and persistent inflammation. Glutathione (GSH) has the therapeutic potential to enhance treatment outcomes by improving antibiotic efficacy, reducing inflammation, and mitigating immune dysfunction. …”
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Sufentanil enhances the cortical neurogenesis of rats with traumatic brain injury via PI3K/AKT signal pathway by Wei Gu, Mimi Wu, Ruocui Zhang, Peiyu Liu, Yang Jiao, Hui Rong

“…The oxidative stress, inflammation, nerve cell damage, melatonin, brain-derived neurotrophic factor (BDNF), neuron regeneration and p-AKT protein level in the cortex were detected with ELISA, TUNEL, qRT-PCR, immunofluorescence and Western blot. …”
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Elevated Serum TNF-α Is Related to Obesity in Type 2 Diabetes Mellitus and Is Associated with Glycemic Control and Insulin Resistance by Hana Alzamil

“…Tumor necrosis factor alpha (TNF-α) is a cytokine that is released by adipocytes and inflammatory cells in response to chronic inflammation. Type 2 diabetes mellitus (T2DM) is believed to be associated with low-grade chronic inflammation. …”
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Serum Calprotectin Level as an Inflammatory Marker in Newly Diagnosed Hypertensive Patients by Nergiz Bayrakci, Gülsüm Ozkan, Sonat Pinar Kara, Ahsen Yilmaz, Savas Guzel

“…The purpose of this study was to evaluate inflammation through serum calprotectin levels in newly diagnosed primary hypertension patients. …”
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Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls by Christian N. Schmitz, Gebhard Sammer, Elena Neumann, Carlo Blecker, Gerhard Gründer, Hana Adolphi, Eva Kathrin Lamadé, Bruno Pedraz-Petrozzi

“…In human studies, inflammation has been shown to act as a critical disease modifier, promoting susceptibility to depression and modulating specific endophenotypes of depression. …”
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Inhibitory Effects of Polaprezine on the Inflammatory Response to Helicobacter pylori by Osamu Handa, Norimasa Yoshida, Yukiko Tanaka, Miho Ueda, Takeshi Ishikawa, Tomohisa Takagi, Naoyuki Matsumoto, Yuji Naito, Toshikazu Yoshikawa

“…Helicobacter pylori-infected gastrointestinal mucosa is frequently infiltrated by polymorphonuclear leukocytes (PMN) and monocytes, and these invading cells have been implicated in gastrointestinal mucosal inflammation. To clarify the efficacy of polaprezinc, a chelate compound consisting of zinc and L-carnosine, against H pylori-induced inflammation including PMN infiltration, the in vitro effects of this drug on interleukin (IL)-8 production by an established gastric cancer cell line (MKN 45 cells) and on PMN-endothelial cell adhesive interactions was investigated. …”
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The road ahead: emerging therapies for primary IgA nephropathy by Edward J. Filippone, Rakesh Gulati, John L. Farber

“…Our current approach for those requiring immunosuppression involves combining the reduction of Gd-IgA1 (nefecon) with suppressing the effects of inflammation (iptacopan). The optimal duration of such therapy is uncertain. …”
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Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration by Susanne W. Bruun, Knud Josefsen, Julia T. Tanassi, Aleš Marek, Martin H. F. Pedersen, Ulrik Sidenius, Martin Haupt-Jorgensen, Julie C. Antvorskov, Jesper Larsen, Niels H. Heegaard, Karsten Buschard

“…In NOD mice and in non-diabetes-prone mice, it induces inflammation in the pancreatic lymph nodes, suggesting that gluten can initiate inflammation locally. …”
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Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing by Latha Satish, Sandeep Kathju

“…In contrast, fetal wound repair occurs with minimal inflammation, faster re-epithelialization, and without the accumulation of scar. …”
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Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries by Julia G. Shaw, Jennifer F. Friedman

“…Infectious diseases, particularly parasitic diseases, also lead to both extracorporeal iron loss and anemia of inflammation, which decreases bioavailability of iron to host tissues. …”
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Conservative Approach in the Management of Radicular Cyst in a Child: Case Report by Narendra Varma Penumatsa, Srinivas Nallanchakrava, Radhika Muppa, Arthi Dandempally, Priyanaka Panthula

“…It arises from epithelial residues in the periodontal ligament as a result of inflammation. The inflammation usually follows the death of dental pulp. …”
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Enhancing the effectiveness of immunotherapy in rheumatoid arthritis by delaying immunosenescence triggered by fibroblast-like synoviocytes by Li Zhang, Yang Luo, Hai-Li Shen

“…Notably, senescent T cells contribute to inflammation, further accelerating the disease process. …”
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Total Body Sodium Balance in Chronic Kidney Disease by Kylie Martin, Sven-Jean Tan, Nigel D. Toussaint

“…Excess sodium intake is a leading but modifiable risk factor for mortality, with implications on hypertension, inflammation, cardiovascular disease, and chronic kidney disease (CKD). …”
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Update on Clinical Inflammometry for the Management of Airway Diseases by Parameswaran Nair

“…Airway inflammation is a central feature of many airway diseases such as asthma, chronic bronchitis, bronchiectasis and chronic cough; therefore, it is only logical that it is measured to optimize its treatment. …”
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De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report by Maria Gergoudis, Logan Laubach, Glenn E. Lee, Jeffrey R. Donowitz

“…We hypothesize that viral-induced systemic inflammation led to localized recurrence of inflammation within the tendon sheath. …”
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The Role of PPARs in the Endothelium: Implications for Cancer Therapy by David Bishop-Bailey, Karen E. Swales

“…This review will discuss the roles of PPARs in endothelial cells in relation to angiogenesis, inflammation, coagulation, and platelet control pathways. …”
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Suberosin attenuates rheumatoid arthritis by repolarizing macrophages and inhibiting synovitis via the JAK/STAT signaling pathway by Huan Liu, Qianwei Li, Yuehong Chen, Min Dong, Hongjiang Liu, Jiaqian Zhang, Leiyi Yang, Geng Yin, Qibing Xie

“…In vivo, prophylactic treatment of low-dose SBR reduced M1 macrophage infiltration into synovial tissue, increased the proportion of M2 macrophages, and decreased the expression of inflammatory mediators in the serum and synovial tissue, alleviating synovial inflammation. SBR significantly alleviated arthritis in CIA mice through macrophage repolarization and inhibition of inflammation. …”
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MicroRNA-122 protects against interferon-α-induced hepatic inflammatory response via the Janus kinase–signal transducer and activator of transcription pathway by Fanwei Liu, Bowen Liu, Shanshan Xu, Yinhua Ni, Xiaoli Liu

“…Additionally, IFN-α significantly activated the NF-κB p-p65, MAPK p-p38, and Jak/STAT pathways to trigger inflammation. Importantly, supplementation with a miR-122 mimic significantly alleviated IFN-α-induced inflammation and induced IFIT1 expression in LO2 cells. …”
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S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis by Panpan Lian, Li Li, Renwei Lu, Bin Zhang, Junaid Wazir, Chaode Gu, Bojie Ma, Wenyuan Pu, Wangsen Cao, Zhiqiang Huang, Zhonglan Su, Hongwei Wang

“…Importantly, we reveal a previously unrecognized positive feedback loop wherein activated STAT3 directly upregulates S1PR3 expression, perpetuating inflammation and hyperproliferation. Genetic deletion of S1pr3 in mice or pharmacological inhibition of S1PR3 significantly attenuates psoriasis-like skin inflammation, decreasing epidermal hyperplasia, dermal angiogenesis, and inflammatory mediator production. …”
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