Review of Anti-Inflammatory Herbal Medicines by Mona Ghasemian, Sina Owlia, Mohammad Bagher Owlia

“…Since the treatment of inflammation is not a one-dimensional remedy, this review tries to reach a multidimensional therapeutic approach to inflammation with the help of herbal medicine and modification in lifestyle.…”
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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells by Steven Timmermans, Steven Timmermans, Charlotte Wallaeys, Charlotte Wallaeys, Somara De Beul, Somara De Beul, Natalia Garcia-Gonzales, Natalia Garcia-Gonzales, Claude Libert, Claude Libert

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Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction by Fei Wang, Yajuan He, Naijuan Yao, Litao Ruan, Zhen Tian

“…Background. Inflammation is a critical factor in the development and progression of myocardial infarction and cardiac fibrosis. …”
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Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

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Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein by Ozlem Ozer Cakir, Siddika Findik

“…Histopathologic investigation revealed a statistically significant difference between the groups in mean congestion, edema, tubular injury, perirenal fat tissue inflammation, and tubular stasis scores in kidney tissue (P<0.001, P<0.001, P<0.001, P<0.001, and P=0.048, respectively); mean congestion, edema, neutrophil inflammation, mononuclear inflammation, and emphysematous change scores in the lung (P<0.001, P<0.001, P<0.001, P=0.030, and P<0.001, respectively); mean congestion, edema, and neutrophil inflammation scores in the stomach (P=0.008, P=0.014, and P<0.001, respectively); and mean congestion and hydropic degeneration scores in the liver (P=0.029 and P=0.002, respectively). …”
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The effects of Stemregen® host modulation therapy on experimentally induced apical periodontitis in rats* by Fatma GÖNÜLLÜ, Mevlüt Sinan OCAK, Serkan DUNDAR, İbrahim Hanifi ÖZERCAN

“…Abstract This study evaluated the effect of Stemregen® nutritional supplement on inflammation and resorption in apical periodontitis using a rat model. …”
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Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss by Tania N. Crotti, Anak A. S. S. K. Dharmapatni, Ekram Alias, David R. Haynes

“…This is pertinent to immune-mediated diseases, such as rheumatoid arthritis and periodontal disease, where there are chronic inflammation and local bone erosion. Periprosthetic osteolysis is another example of chronic inflammation with associated osteolysis. …”
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Increased interferon I signaling, DNA damage response and evidence of T-cell exhaustion in a patient with combined interferonopathy (Aicardi-Goutières Syndrome, AGS) and cohesinopa... by Sorina Boiu, Nikolaos Paschalidis, George Sentis, Theodora Manolakou, Andrianos Nezos, Manolis Gialitakis, Maria Grigoriou, Erato Atsali, Melpomeni Giorgi, Argirios Ntinopoulos, Clio Mavragani, Periklis Makrythanasis, Dimitrios T. Boumpas, Aggelos Banos

“…Immune phenotype revealed granulocytic skewing and absence of activated T cells compatible with chronic antigenic stimulation and/or homing of these cells at sites of inflammation.…”
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From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges by Wei Du, Xinyue Wang, Yuyan Zhou, Wencheng Wu, Haojie Huang, Zhendong Jin

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Cysteinyl Leukotriene Receptor-1 Antagonists as Modulators of Innate Immune Cell Function by A. J. Theron, H. C. Steel, G. R. Tintinger, C. M. Gravett, R. Anderson, C. Feldman

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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain by Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Soo-Jin Song, Jung-A Shin, Chulhee Choi, Heon Yung Gee, Youn-Hee Choi

“…Single-cell RNA sequencing revealed that these anti-inflammatory exosomes targeted macrophages and microglia, reducing the expression of inflammation-related genes. Treatment with Exo-srIκB also suppressed the interactions between macrophages/microglia and T and B cells in the aged brain. …”
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Impact of COVID-19 on Ocular Surface Health: Infection Mechanisms, Immune Modulation, and Inflammatory Responses by Duliurui Huang, Weixia Xuan, Zhijie Li

“…The review also examines the roles of cytokines and chemokines in mediating ocular surface inflammation and explores the impact of cytokine storms and chronic inflammation on ocular health. …”
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Proinflammatory Stimuli Enhance Phagocytosis of Apoptotic Cells by Neutrophil Granulocytes by Lars Hellberg, Sabrina Fuchs, Christoph Gericke, Arup Sarkar, Martina Behnen, Werner Solbach, Tamás Laskay

“…These results support the hypothesis that neutrophils acquire the ability to phagocytose apoptotic cells at sites of acute infection/inflammation and thereby can contribute to the resolution of inflammation.…”
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Prion Diseases and the Gastrointestinal Tract by Gwynivere A Davies, Adam R Bryant, John D Reynolds, Frank R Jirik, Keith A Sharkey

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Post-pandemic insights on COVID-19 and premature ovarian insufficiency by Han Yaguang, Dai Yang, Wang Kexin, Zhang Xin, Shao Zishen, Zhu Xiaolin

“…Long-term health effects, such as “long COVID,” may exacerbate these issues through chronic inflammation and immune dysfunction. Public health measures, such as vaccination and home isolation, may indirectly protect ovarian health by reducing systemic inflammation. …”
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Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells by Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt

“…Sickle cell disease is a genetic disease that increases systemic inflammation as well as the risk of pediatric strokes, but links between sickle-induced inflammation and arterial remodeling are not clear. …”
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Adipocyte-specific Steap4 deficiency reduced thermogenesis and energy expenditure in mice by Han Wang, Lizi Zhang, Xing Chen, Lingzi Hong, Junjie Zhao, Wen Qian, Lam Khue Pham, Belinda Willard, Xiaoxia Li, Katarzyna Bulek, Xiao Li

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Host Epithelial Interactions with Helicobacter Pylori: A Role for Disrupted Gastric Barrier Function in the Clinical Outcome of Infection? by Andre G Buret, Jason P Fedwick, Andrew N Flynn

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Autophagy in Inflammatory Diseases by Alexander J. S. Choi, Stefan W. Ryter

“…Strategies aimed at modulating autophagy may lead to therapeutic interventions for diseases associated with inflammation.…”
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Recurrent bilateral idiopathic anterior uveitis with vitritis post Coronavirus Disease 2019 infection by Srinivasan Sanjay, Yogesh Preet Singh, Debaditya Roy, Padmamalini Mahendradas, Ankush Kawali, Rohit Shetty

“…After initiation of oral steroids and immunosuppression the ocular inflammation is now under remission. This report illustrates that the presence of COVID-19 antibodies may presumably play a role in triggering the immune system, this can cause recurrent ocular inflammation in absence of other extraocular inflammation.…”
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