A Rare Case of Spontaneous Heterotopic Pregnancy at 12 weeks of Gestation Following Natural Conception With Literature Review by Wang F, Xu Y, Dong X, Jiang P, Yu QQ

“…Postoperative β-HCG levels were 49,213 mIU/mL and 57,577 mIU/mL on the second and third days, respectively.Conclusion: Clinicians should maintain vigilance for heterotopic pregnancy, especially in the absence of infertility treatments or known risk factors. Lower quadrant abdominal or pelvic pain should prompt consideration of heterotopic pregnancy, as the presence of an intrauterine pregnancy does not exclude a concurrent ectopic pregnancy.Keywords: ectopic pregnancy, heterotopic pregnancy, laparoscopy, spontaneous pregnancy…”
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Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning by Jianhui Chen, Qun Li, Xiaofang Liu, Fang Lin, Yaling Jing, Jiayan Yang, Lianfang Zhao

“…ObjectiveEndometriosis (EMs) is a chronic inflammatory disease characterized by the presence of endometrial tissue in the non-uterine cavity, resulting in dysmenorrhea, pelvic pain, and infertility. Epidemiologic data have suggested the correlation between EMs and recurrent pregnancy loss (RPL), but the pathological mechanism is unclear. …”
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The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank by Huanyu Guo, Yingzi Sun, Wei Gao, Yuqing Liu, Tianshu Han, Dandan Zhang

“…These disorders include polycystic ovary syndrome (PCOS), heavy menstrual bleeding (HMB), endometriosis, infertility, and pregnancy-related disorders. This study aims to investigate the associations of activity patterns with female reproductive diseases. …”
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Posterior Urethral Valves and Fertility: Insight on Paternity Rates and Seminal Parameters by Marcello Della Corte, Simona Gerocarni Nappo, Antonio Aversa, Sandro La Vignera, Francesco Porpiglia, Cristian Fiori, Nicola Mondaini

“…PUV diagnoses are common in adults exhibiting infertility and ejaculation disorders, suggesting PUVs cannot be considered only a pediatric disease. …”
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Evaluation and diagnostic approach in patient with Perrault Syndrome by Rachael Christin Nathania, Steven Yulius Usman, Ekarini Aryasatiani

“…The patient expressed concern about potential future infertility. At age 9, she was diagnosed with a viral infection by an ENT specialist due to bilateral hearing loss, leading to emotional disturbances. …”
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Who freezes her eggs and why? psychological predictors, reasons, and outcomes of social egg freezing by Julia Jeannine Schmid, Seraina Weber, Ulrike Ehlert

“…The probability of belonging to the SEF + ART-use group rather than SEF-use depended mainly on the presence of infertility. The women froze eggs mainly to gain time to fulfill their desire for conventional parenthood (59%), including finding the right partner and enabling a genetic relationship to the child. …”
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Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind... by Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

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Chorein deficiency promotes ferroptosis by Yoshiaki Nishizawa, Hitoshi Sakimoto, Omi Nagata, Natsuki Sasaki, Yuka Urata, Kaoru Arai, Hanae Hiwatashi, Izumi Yokoyama, Shosei Kishida, Akira Sano, Masayuki Nakamura

“…In our previous study, we found male infertility characterized by increased malondialdehyde staining of the spermatozoa in the testes of the ChAc model mice. …”
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Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis by Lu Sun, Jiayu Huang, Xuezi Wang, Peng Huang, Baolin Dong, Zehang Liang, Jiahong Wu, Jiancheng Wang

“…Conclusions In summary, this study pioneered the application of stromal cell enucleation technology to repair tissue damage in the reproductive system, explored the potential of cell burial in the treatment of reproductive system diseases and provided a new approach for the clinical treatment of male infertility.…”
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Critical factors influencing live birth rates in fresh embryo transfer for IVF: insights from cluster ensemble algorithms by Zheng Yu, Xiaoyan Zheng, Jiaqi Sun, Pengfei Zhang, Ying Zhong, Xingyu Lv, Hongwen Yuan, Fanrong Liang, Dexian Wang, Jie Yang

“…Abstract Infertility has emerged as a significant global health concern. …”
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In vitro effect of hCG on cryptorchid patients’ gubernacular cells: a predictive model for adjuvant personalized therapy by Andrea Errico, Giulia Ambrosini, Sara Vinco, Emanuela Bottani, Elisa Dalla Pozza, Nunzio Marroncelli, Jessica Brandi, Daniela Cecconi, Ilaria Decimo, Filippo Migliorini, Nicola Zampieri, Ilaria Dando

“…Abstract Background Cryptorchidism is the absence of one or both testicles in the scrotum at birth, being a risk factor for testis cancer and infertility. The most effective method to treat cryptorchidism is orchiopexy, followed by human chorionic gonadotropin (hCG) therapy; however, a portion of treated patients do not show a significant improvement in testis volume and vascularization after adjuvant therapy. …”
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Correlations between Different Heavy Metals in Diverse Body Fluids: Studies of Human Semen Quality by Lidia Mínguez-Alarcón, Jaime Mendiola, Manuela Roca, José J. López-Espín, José J. Guillén, José M. Moreno, Stella Moreno-Grau, María J. Martínez-García, Nuria Vergara-Juárez, Belén Elvira-Rendueles, Antonio García-Sánchez, Jorge Ten, Rafael Bernabeu, Alberto M. Torres-Cantero

“…Sixty-one men attending infertility clinics participated in our study. Concentrations of lead, cadmium, and mercury were measured in whole blood, blood plasma, and seminal plasma using spectroanalytical and electrochemical methods. …”
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The Association between Deoxyribonucleic Acid Hypermethylation in Intron VII and Human Leukocyte Antigen-C∗07 Expression in Patients with Endometriosis by Wenrong Zhao, Lei Lei, Rui Chen, Yanmin Zhang, Linlin Chang, Jingxin Cheng

“…Endometriosis, which is a common disease affecting approximately 10% of women of reproductive age, usually causes dysmenorrhea and infertility, thus seriously harming the patients’ physical and mental health. …”
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Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures by Dandan Cao, Yijun Liu, Yanfei Cheng, Jue Wang, Bolun Zhang, Yanhui Zhai, Kongfu Zhu, Ye Liu, Ye Shang, Xiao Xiao, Yi Chang, Yin Lau Lee, William Shu Biu Yeung, Yuanhua Huang, Yuanqing Yao

“…Abstract Understanding human endometrial dynamics in the establishment of endometrial receptivity remains a challenge, which limits early diagnosis and treatment of endometrial-factor infertility. Here, we decode the endometrial dynamics of fertile women across the window of implantation and characterize the endometrial deficiency in women with recurrent implantation failure. …”
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Factors Influencing the Pregnancy Outcome of Intrauterine Insemination and Follow-Up Treatment by Xuan Huang, Qin Sun, Xu Tang, Meiling Li, Cheng Zhou, Xi Cheng, Bing Yao, Li Chen

“…Settings and Design: The clinical data of 1232 IUI cycles in 690 couples experiencing infertility who attended the Reproductive Center of Jinling Hospital between July 2015 and November 2021 were retrospectively analysed. …”
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Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies* by Fleur Serge Kanti, Rose Gorak Savard, Frédéric Bergeron, Hervé Tchala Vignon Zomahoun, Antoine Netter, Sarah Maheux-Lacroix

“…Introduction The diagnosis of endometriomas in patients with endometriosis is of primary importance because it influences the management and prognosis of infertility and pain. Imaging techniques are evolving constantly. …”
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Semen Parameters Can be Used as a Credible Marker with Doppler Ultrasonography in the Diagnosis of Subclinical Varicocele Cases by Tulay Irez, Bahar Sarikaya, Mine Erguven, Emre Salabas

“… OBJECTIVES: The link between varicoceles and male infertility has been a problem of debate for more than half a century. …”
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Theophylline Revisited. Mechanisms, Challenges, and New Horizons by Jakub Szarłowicz, Michał Mazur, Dorota Waz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Klaudia Fikas, Kamil Chwaliszewski, Sebastian Samuła

“…It demonstrates potential in COVID-19-related ARDS, promoting muscle regeneration, and treating infertility. However, its narrow therapeutic index and variability in pharmacokinetics remain significant challenges. …”
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ucumeropsis mannii seed oil protects against Bisphenol A- induced testicular mitochondrial damages by Patrick Maduabuchi, Aja, Hilary Akobi, Ogwoni, Peter Chinedu, Agu, Ejike Ugbala, Ekpono, Joshua Nonso, Awoke, Oliver Ugochukwu, Ukachi, Obasi Uche, Orji, Boniface Anthony, Ale, Chinonso Peter, Nweke, Esther Ugo, Alum, Darlington C., Chukwu, Christian E., Offor, Atamgba Agbor, Asuk, Ejike, Daniel Eze, Ojochenemi E., Yakubu, J. B., Akob, Onyedika Gabriel, Ani, Chinaza Godswill, Awuchi

“…here has been increasing search for the ameliorative properties of seed oils against toxicants. bisphenol A acts as an estrogenic endocrine-disrupting chemical capable of causing male infertility. This study aimed to explore Cucumeropsis mannii seed oil effects against mitochondrial damage in rats using bisphenol A. …”
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Characterisation of Chemical Constitutes and Spermatogenic Activity of Ushir (Vetiveria Zizanioides Linn) versus Ikshu (Saccharum Officinarum Linn) in Male Wistar Rats: A Research... by Akshay Sudhir Pargaonkar, Jaymala Jadhav, Bhagyashree Ratan Jibkate, Minakshi Urkude

“…Introduction: In men, infertility may results from impaired sperm quality, quantity and abnormalities. …”
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