Chronic Inflammation May Enhance Leiomyoma Development by the Involvement of Progenitor Cells by Monia Orciani, Miriam Caffarini, Alessandra Biagini, Guendalina Lucarini, Giovanni Delli Carpini, Antonella Berretta, Roberto Di Primio, Andrea Ciavattini

“…The evidenced cytokine expression pattern related to chronic inflammation in LPCs may play a role in the increased risk of adverse obstetric outcomes (infertility, spontaneous miscarriage, and preterm birth) in women affected by leiomyomas. …”
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Optimal Timing for Oocyte Denudation and Intracytoplasmic Sperm Injection by Catherine Patrat, Aida Kaffel, Lucie Delaroche, Juliette Guibert, Pierre Jouannet, Sylvie Epelboin, Dominique De Ziegler, Jean-Philippe Wolf, Patricia Fauque

“…We included ICSI cycles with the following parameters: rank 1 or 2, female age <36 years, male factor infertility, long protocol using GnRH agonist and rFSH for ovarian stimulation, and use of freshly ejaculated sperm (𝑛=110). …”
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Autologous haematopoiesis stem cell transplantation (AHSCT) for treatment-refractory autoimmune diseases in children by Jasmin Beate Kuemmerle-Deschner, Susanne Benseler, Joerg C Henes, Özlem Satirer, Michaela Döring, Till Lesk

“…Treatment toxicity: one cyclophosphamide-associated transient renal failure and pericardial effusion, one patient with amenorrhoea/infertility.Conclusions AHSCT was an effective and safe approach for children and adolescents with treatment-refractory autoimmune diseases. …”
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Acupuncture mediates the “gut–testis axis” to improve asthenozoospermia by Jianheng Hao, Jianheng Hao, Huichao Xu, Boya Chang, Jia Ren, Haijun Wang, Laixi Ji, Laixi Ji

“…BackgroundAsthenozoospermia is a common cause of male infertility. Studies have shown that sperm quality and motility are affected by the gut–testis axis that can regulate testicular metabolism and function through the gut microbiota and its metabolites. …”
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Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome by Zhuo Liu, Rui-Han Wang, Ke-Hua Wang

“…Abstract Background Polycystic ovary syndrome (PCOS) is a common gynecological disease accompanied by multiple clinical features, including anovulation, hyperandrogenism, and polycystic ovarian morphology, leading to infertility. Formononetin (FMN), which is a major bioactive isoflavone compound in Astragalus membranaceus, exerts anti-inflammatory effects. …”
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Investigation of the Relationship between Chronic Endometritis Manifestations under Hysteroscope and CD138 Expression by Shuang Wang, FengHua Li, Wei Zhang, XiaoLong Sui, CuiFang Hao

“…In the comparison of overall status for all patient cohorts, infertility type, BMI, bFSH, bLH, bP, bT, PRL, AMH, and CA125 were varied markedly across all cohorts (P<0.05), with predominant incidences of polycystic ovary syndrome (PCOS) peaking within hyperemia cohort. …”
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Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin by Stefano Radellini, Valentina Guarnotta, Vincenzo Sciabica, Giuseppe Pizzolanti, Carla Giordano

“…Klinefelter’s syndrome (KS) is the main cause of hypogonadism and infertility in men and is often related to obesity, metabolic syndrome, and diabetes. …”
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Factors influencing childbirth fear among Asian women: a scoping review by Aida Kalok, Aida Kalok, Ixora Kamisan Atan, Shalisah Sharip, Nazarudin Safian, Shamsul Azhar Shah

“…Greater levels of tokophobia were linked to nulliparity, unplanned pregnancy, infertility, miscarriage, and pregnancies at risk. Effective doctor-patient communication and more frequent antenatal visits were shown to alleviate maternal childbirth fear. …”
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Second Trimester Abortion: A Dilation and Evacuation Simulation for Gynecologic Surgery and Obstetrics Residents by Kiley Hunkler, David Boedeker, Elizabeth Gill, Katelyn Simpkins, Katerina Shvartsman, Jill Brown, Sara Drayer

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Isolation of Viable Follicles from Cryopreserved Human Ovarian Tissue by Farnaz Tajbakhsh, Somayeh Tavana, Mohammad Kazemi Ashtiani, Naeimeh Sadat Abtahi, Leila Sadat Tahaei, Ashraf Moini, Rouhollah Fathi

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Assessment of patient preferences for assisted reproductive technology in China: a discrete choice experiment by Lingli Zhang, Xin Li, Jiali Chen, Yanyan Liu, Yanjun Sun, Yuwen Bao, Xiaodan Qian, Kexing Fang, Bin Wan, Haixia Ding

“…Preferences varied according to their age, monthly household income and location.Conclusions This study investigated the preferences of infertile patients when seeking medical assistance for infertility. …”
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Effects of L-carnitine and pentoxifylline on long-term preservation of the human sperms: An experimental study by Elham Aliabadi, Zohre Nateghian, Mohammad Hossein Nasr-Esfahani, Marziyeh Tavalaee, Tahereh Talaei-Khozani

“… Background: In infertility clinics, long-time preserving high-quality spermatozoa is a challenging problem. …”
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Exploring the need for fertility education: A cross-sectional study of healthcare professionals and students’ knowledge of fertility and fertility preservation by Ana GALHARDO, Catarina SALVADO, Soraia MONIZ, Marina Cunha, Ilda MASSANO-CARDOSO

“…Results: Most participants were aware of the infertility definition and prevalence, but 41.2% of students and 37.9% of professionals needed to recognize that men's age may also impact fertility. …”
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Comparison of the Efficacy and Tolerability of Dienogest and Dienogest Plus Ethinylestradiol on Endometriosis Related-Pain by Tolga Karacan, Huseyin Kiyak, Eser Ozyurek, Mevlide San, Engin Oral

“… Objective: Endometriosis is a common gynecological condition that affects many women of reproductive age worldwide and is a major cause of pain and infertility. Treatment of endometriosis can be either surgical, aiming to restore normal anatomy by removing endometriotic lesions, or hormonal. …”
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Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis by Chun-Wei Chen, Jeffery B Chavez, Ritikaa Kumar, Virginia Arlene Go, Ahvani Pant, Anushka Jain, Srikanth R Polusani, Matthew J Hart, Randal D Robinson, Maria Gaczynska, Pawel Osmulski, Nameer B Kirma, Bruce J Nicholson

“…Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells retrogradely enter the peritoneum during menses, and implant and form invasive lesions in a process analogous to cancer metastasis. …”
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Relation of Follicular Fluid Soluble Receptor for Advanced Glycation End-Products Concentration and Anti Mullerian Hormone in Polycystic Ovary Syndrome and Non-PCOS Women Referring... by Neda Emami, Ashraf Moini, Samira Vesali

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Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls by Mustafa Demir, Onur Ince, Bulent Yilmaz, Mert Ulas Barut, Ulviye Cansu Ozturk, Avni Kılıc, Ahmet Berkiz Turp, Recep Sutcu, Seyithan Taysi

“… OBJECTIVE: Polycystic ovary syndrome, myoma uteri and endometrioma are frequently seen gynecologic problems and all three diseases may cause infertility. Aim of this cross-sectional study was to compare total antioxidant status, ceruloplasmin, total sulfhydryl , total oxidant status, lipid hydroperoxide and oxidative stress index levels in endometrial flushing fluid of patients with Polycystic ovary syndrome (n=20), uterine leiomyoma (n=20), endometrioma (n=19), and healthy women (n=20). …”
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Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY stud... by Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki

“…Abstract Background Endometriosis presents as endometrial tissue growths outside the uterine cavity with its major symptoms including dysmenorrhea and infertility. Progestin preparations, such as dienogest, are the first-line therapy for endometriosis symptoms, but may cause abnormal uterine bleeding. …”
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DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression by Rui Hua, Qingjun Chu, Feiyan Guo, Qinjie Chen, Maocai Li, Xuan Zhou, Yongtong Zhu

“…DNM3OS was found to regulate the apoptosis and senescence of spermatogonia by providing miR-214-5p and decreasing E2F2 expression, suggesting it as a novel target for gene therapy of male infertility.…”
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Analysis of toxicity and mechanisms of busulfan in non-obstructive azoospermia: A genomic and toxicological approach integrating molecular docking, single-cell sequencing, and expe... by Yanggang Hong, Qichao Yuan, Yi Wang, Deqi Wang, Xiaoju Guan, Congde Chen

“…Non-obstructive azoospermia (NOA) is a severe form of male infertility caused by intrinsic testicular dysfunction, leading to a complete absence of sperm in the ejaculate. …”
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