Endometrial Receptivity–Lessons from “Omics” by Louie Ye, Evdokia Dimitriadis

“…Drawing on findings from various branches of “omics”, including genomics, epigenomics, transcriptomics, proteomics, lipidomics, metabolomics, and microbiomics, this narrative review aims to (1) discuss mechanistic insights on endometrial receptivity and its implication in infertility; (2) highlight advances in investigations for endometrial receptivity; and (3) discuss novel diagnostic and therapeutic strategies that may improve reproductive outcomes.…”
Get full text

Sperm DNA fragmentation index: limited effectiveness on predicting embryo quality in assisted reproduction technology treatments by Huan Jiang, Xiaolu Xia, Ying Luo, Haiyan Pan, Shihao Qu, Jianying Xu

“…Abstract Purpose Prior sperm DNA fragmentation index (DFI) thresholds for diagnosing male infertility and predicting assisted reproduction technology (ART) outcomes fluctuated between 15 and 30%, with no agreed standard. …”
Get full text

The Effect of Maternal Body Mass Index on in Vitro Fertilization-Intracytoplasmic Sperm Injection Treatment: A Prospective Comparative Study by Zeynep Ozturk Inal, Hasan Ali Inal

“…Results: While there were no differences between the groups in terms of age, smoking status, etiology of infertility, thyroid-stimulating hormone, prolactin levels, antral follicle count, and stimulation protocol (p>0.05), there was a significant statistical difference in terms of body mass index, duration of infertility, baseline follicle-stimulating hormone, luteinizing hormone, estradiol (E2), duration of stimulation, total gonadotropin dose required, peak E2 levels, progesterone levels, endometrial thickness on hCG administration, and cycle cancellation rate (p<0.05). …”
Get full text

Impact of Long-term Polyvinylpyrrolidone Exposure on Gene Expression, Chromatin Structure, and Malondialdehyde Levels in Human Sperm by Mojdeh Sabour, Mahmood Dehghani Ashkezari, Azam Agharahimi, Seyed Morteza Seifati, Seyed Mehdi Kalantar

“…Since PVP is used widely in infertility centers, it is noteworthy to investigate the side effects of this agent. …”
Get full text

The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

Get full text

Development of the membrane ceiling method for in vitro spermatogenesis by Maki Kamoshita, Hiroki Shirai, Hiroko Nakamura, Tetsuya Kishimoto, Yuki Hatanaka, Daisuke Mashiko, Katsuhiro Esashika, Jingjing Yang, Satoshi Yamasaki, Takehiko Ogawa, Hiroshi Kimura, Masahito Ikawa

“…Abstract Spermatogenesis is one of the most complex processes of cell differentiation and its failure is a major cause of male infertility. Therefore, a proper model that recapitulates spermatogenesis in vitro has been long sought out for basic and clinical research. …”
Get full text

Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model by Zhenye Zhu, Min Lei, Ruizhi Guo, Yining Xu, Yanqing Zhao, Chenlu Wei, Qingling Yang, Yingpu Sun

“…Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility among women of reproductive age, yet the range of effective treatment options remains limited. …”
Get full text

Predicting the Health‐Promoting Lifestyle Profile of Pregnant Women Based on Their Health Literacy Levels: A Cross‐Sectional Study by Nastaran Rafat, Fatemeh Bakouei, Hajar Adib‐Rad, Hossein‐Ali Nikbakht, Sareh Bakouei

Get full text

Calcified Leiomyomata Presenting as Recurrent Pregnancy Loss by Mohammad Marwan Alhalabi, Ameer Kakaje, Marwan Alhalabi

“…We report a very rare case of a large calcified leiomyomata which caused secondary infertility and pregnancy loss of 7 pregnancies due to spontaneous abortions.…”
Get full text

Shifting Parenthood to Advanced Reproductive Ages: Trends, Causes and Consequences by Tomáš Sobotka

“…It reviews consequences of delayed childbearing for individuals, couples, their children and society and discusses the limited role of assisted reproduction in offsetting the age-related rise in infertility. The individual social and economic advantages of late parenthood may outweigh the biological advantage of early parenthood. …”
Get full text

L’épée de Damoclès by Giulia Colavolpe Severi

“…This article presents the first results of qualitative research conducted in France from February to June 2012, through sixteen semi-structured interviews with women exposed in utero to diethylstilbestrol (DES), a teratogenic molecule that influences the development of the reproductive apparatus by provoking anomalies liable to cause infertility. The aim of this article is to describe what women exposed in utero to DES have experienced in their bodies in relation to pregnancy. …”
Get full text

Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS) by Pascal Froment, Philippe Touraine

“…Polycystic ovary syndrome (PCOS) is the most frequent cause of female infertility. The treatment of PCOS patients with insulin sensitizers, such as metformin or thiazolidinediones, increases the ovulation rate and the number of successful pregnancies. …”
Get full text

Integrated technique of buffalo fertility management in Nepal by Bhuminand Devkota, Shatrughan Shah, Gokarna Gautam

“…The productive efficiency of Nepalese buffaloes is relatively low, due mainly to subfertility and infertility. Delayed puberty and prolonged inter-calving intervals, attributed mainly to anestrus due to silent cyclicity and ovarian acyclicity, are the major forms of infertility in Nepalese buffaloes. …”
Get full text

Clinical Pregnancy and Miscarriage Rates in relation to Vitamin D Supplementation among women with Hyper Androgenic PCOS: A prospective study by Sherif Sobhy Menshawy Khalifa, Wael Gaber Eldamaty, Ahmed Tharwat Abo Dakika, Mohamed Zaeim Hafez Ahmed, Muhammad Abdelbaeth Hassan Elfiky, Ghada Adel Hegazy

“…Determining 25(OH)D status as part of a routine infertility assessment may therefore be advantageous.…”
Get full text

Is There a Role of 25-Hydroxy Vitamin D in the Pathogenesis of Mild and Moderate-to-Severe Endometriosis? by Nevin Tuten, Serdar Acikgoz, Zahid Mammadov, Eduard Malik, Abdullah Tuten, Onur Guralp

“…The serum 25-hydroxy vitamin D levels had no correlation with the presence of infertility, deep infiltrating endometriosis, or Douglas pouch obliteration. …”
Get full text

The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps by Aytekin Tokmak, Ebru Ersoy, Ali Özgür Ersoy, Esra Yaşar Çelik, Ali İrfan Güzel, Mustafa Uğur

“…The median BMI, gravidity, parity and abortion were significantly higher in study group (p<0.05). Infertility was more common in control group (65.5% vs. 10.8%; p<0.001). …”
Get full text

Complications of Uterine Fibroids and Their Management, Surgical Management of Fibroids, Laparoscopy and Hysteroscopy versus Hysterectomy, Haemorrhage, Adhesions, and Complications by Liselotte Mettler, Thoralf Schollmeyer, Andrea Tinelli, Antonio Malvasi, Ibrahim Alkatout

“…Very seldom does peritonitis occur. Infertility may result from continuous metro and menorrhagia. …”
Get full text

Delayed Interval Delivery following Early Loss of the Leading Twin by P. C. Udealor, I. V. Ezeome, F. C. Emegoakor, D. O. Okeke, P. C. N. Okere

“…This was a case of a nulliparous woman with reduced chance of conception following unilateral salpingectomy and years of infertility. She eventually conceived following ovulation induction resulting in twin pregnancy. …”
Get full text

Angioembolization of Scrotal Arteriovenous Malformations: A Case Report and Literature Review by Ammar Mohammad, Wael Sahyouni, Taisser Almeree, Bayan Alsaid

“…Arteriovenous malformations (AVMs) of the scrotum are rare lesions, usually diagnosed incidentally during the evaluation of scrotal masses or infertility. It could be presented with acute bleeding or acute pain. …”
Get full text

Genital Schistosomiasis Leading to Ectopic Pregnancy and Subfertility: A Case for Parasitic Evaluation of Gynaecologic Patients in Schistosomiasis Endemic Areas by Atta Owusu-Bempah, Alexander Tawiah Odoi, Edward Tieru Dassah

“…Female genital schistosomiasis is a significant risk factor for ectopic pregnancy and infertility in schistosomiasis-endemic areas. A case of one previous ectopic pregnancy and subsequent obstruction of the contralateral tube in a secondary subfertility patient with chronic genital schistosomiasis is presented, emphasizing the need for a detailed history and parasitic evaluation of patients presenting with ectopic pregnancy or subfertility in areas where the disease is endemic.…”
Get full text