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    PCSK9: A Potential Therapeutic Target for Sepsis by Yuan Yuan, Wei Wu, Shanshan Sun, Yi Zhang, Zhi Chen

    Published 2020-01-01
    “…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is often upregulated in the presence of sepsis and infectious diseases. In sepsis, PCSK9 degraded the low-density lipoprotein cholesterol (LDL) receptors (LDL-R) of the hepatocytes and the very low-density lipoprotein cholesterol receptors (VLDL-R) of the adipocytes, which then subsequently reduced pathogenic lipid uptake and clearance/sequestration. …”
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    Etiological Aspects of Infectious Endocarditis in a Tertiary Hospital in Northeastern Romania by Isabela Ioana Loghin, Amelia Elena Surdu, Șerban Alin Rusu, Ion Cecan, Victor Daniel Dorobăț, Amelia Andreea Mihăescu, Carmen Mihaela Dorobăţ

    Published 2025-01-01
    “…Parascheva” Clinical Hospital of Infectious Diseases in Iasi, Romania, and retrospectively analyzed cases of IE from January 1, 2019, to September 30, 2024. …”
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