Immunobridging Trials: An Important Tool to Protect Vulnerable and Immunocompromised Patients Against Evolving Pathogens by Pedro Cruz, Jie Min Lam, Jehad Abdalla, Samira Bell, Jola Bytyci, Tal Brosh-Nissimov, John Gill, Ghady Haidar, Michael Hoerger, Yasmin Maor, Antonio Pagliuca, Francois Raffi, Ffion Samuels, Dorry Segev, Yuxin Ying, Lennard Y. W. Lee

“…Safeguarding patients from emerging infectious diseases demands strategies that prioritise patient well-being and protection. …”
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Does Colorectal Stenting as a Bridge to Surgery for Obstructive Colorectal Cancer Increase Perineural Invasion? by Hiroki Kato, Kazushige Kawai, Daisuke Nakano, Akira Dejima, Ichiro Ise, Soichiro Natsume, Misato Takao, Satomi Shibata, Toshiro Iizuka, Tetsuo Akimoto, Yuichiro Tsukada, Masaaki Ito

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Real-life study on the effectiveness and safety of sofosbuvir/velpatasvir-based antiviral agents for hepatitis C eradication in Chinese patients by Jiayi Wang, Lingyao Du, Dongmei Zhang, Chen Zhou, Yilan Zeng, Miao Liu, Xing Cheng, Xiaona Song, Han Chen, Ning Han, Enqiang Chen, Hong Tang

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Changes in donor lymphocyte infusion for relapsed patients post-hematopoietic stem cell transplantation: a 30-year single-center experience by Yusuke Uchibori, Shuhei Kurosawa, Yuho Najima, Kyoko Haraguchi, Daichi Sadato, Chizuko Hirama, Yasutaka Sadaga, Kaori Kondo, Chika Kato, Satoshi Sakai, Yasuhiro Kambara, Fumihiko Ouchi, Masashi Shimabukuro, Atsushi Jinguji, Naoki Shingai, Takashi Toya, Hiroaki Shimizu, Takeshi Kobayashi, Hironori Harada, Hironori Harada, Yuka Harada, Yoshiki Okuyama, Noriko Doki

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A single residue switch mediates the broad neutralization of Rotaviruses by Yang Huang, Feibo Song, Yuanjun Zeng, Hui Sun, Roufang Sheng, Xuechun Wang, Liqin Liu, Guoxing Luo, Yanan Jiang, Yaling Chen, Mengxuan Zhang, Shiyin Zhang, Ying Gu, Hai Yu, Shaowei Li, Tingdong Li, Qingbing Zheng, Shengxiang Ge, Jun Zhang, Ningshao Xia

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Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1 by Lin-Yu Wan, Sin Man Lam, Hui-Huang Huang, Wen-Jing Cao, Xiang-Yi Cao, Xue-Meng Li, Li-Ping Zhang, Jia-Min Gao, Chao Zhang, Xing Fan, Yan-Mei Jiao, Guanghou Shui, Fu-Sheng Wang, Jin-Wen Song

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Efficacy of Tenofovir-Based Combination Therapy versus Tenofovir Monotherapy in Chronic Hepatitis B Patients Presenting with Suboptimal Responses to Pretreatment: A Meta-Analysis by Ling Chen, Xiwei Wang, Qiongfang Zhang, Jiaojiao Gong, Shasha Shen, Wenwei Yin, Huaidong Hu

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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

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Severe Atelectasis due to Aspirated Valproic Acid Tablet by Tomomi Tanigaki, Takunori Ogawa, Sakika Nomura, Koki Ito, Yuhei Kurata, Akira Matsukida, Morio Ishihara, Aihide Yoshino, Akihiko Kawana, Yoshifumi Kimizuka

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Anti-Tick-Bourne Encephalitis IgM Intrathecal Synthesis as a Prediction Marker in Tick-Borne Encephalitis Patients by Piotr Czupryna, Sambor Grygorczuk, Agnieszka Siemieniako-Werszko, Jakub Okrzeja, Justyna Dunaj-Małyszko, Justyna Adamczuk, Sławomir Pancewicz, Joanna Zajkowska, Karolina Narejko, Joanna Oklińska, Gabriela Trojan, Anna Moniuszko-Malinowska

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PCSK9: A Potential Therapeutic Target for Sepsis by Yuan Yuan, Wei Wu, Shanshan Sun, Yi Zhang, Zhi Chen

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is often upregulated in the presence of sepsis and infectious diseases. In sepsis, PCSK9 degraded the low-density lipoprotein cholesterol (LDL) receptors (LDL-R) of the hepatocytes and the very low-density lipoprotein cholesterol receptors (VLDL-R) of the adipocytes, which then subsequently reduced pathogenic lipid uptake and clearance/sequestration. …”
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A prognostic model of 8-T/B cell receptor-related signatures for hepatocellular carcinoma by Xuan Zuo, Hui Li, Shi Xie, Mengfen Shi, Yujuan Guan, Huiyuan Liu, Rong Yan, Anqi Zheng, Xueying Li, Jiabang Liu, Yifan Gan, Haiyan Shi, Keng Chen, Shijie Jia, Guanmei Chen, Min Liao, Zhanhui Wang, Yanyan Han, Baolin Liao

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Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats by Jiong Yu, Guangshu Hao, Dan Wang, Jingqi Liu, Xiaotian Dong, Yanni Sun, Qiaoling Pan, Yang Li, Xiaowei Shi, Lanjuan Li, Hongcui Cao

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MicroRNA-122 protects against interferon-α-induced hepatic inflammatory response via the Janus kinase–signal transducer and activator of transcription pathway by Fanwei Liu, Bowen Liu, Shanshan Xu, Yinhua Ni, Xiaoli Liu

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Response to Karp-Tatham et al. by Astrid Marchal, Vanessa Sancho-Shimizu, Laurent Abel, Jean-Laurent Casanova, Aurélie Cobat, Alexandre Bolze

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A call to invest in post-TB lung disease to halt TB transmission in communities by P. M. Mbelele, F. J. Mtei, F. Thobias, K. S. Msaji, L. Løchting, L. M. Subi, D. Bwana, R. M. Kisonga, P. Neema, P. Howlett, M. Drage, S. K. Heysell, S. G. Mpagama

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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

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Anti-inflammatory response of IL-4, IL-10 and TGF-β in patients with systemic inflammatory response syndrome by Donato Torre, Roberto Tambini, Silvana Aristodemo, Giovanna Gavazzeni, Antonio Goglio, Carla Cantamessa, Agostino Pugliese, Gilberto Biondi

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Increased Incidence of Rhinovirus Pneumonia in Children During the COVID-19 Pandemic in Mexico by Fanny Yasmin Ortega-Vargas, Aldo Agustin Herrera-González, Ilen Adriana Díaz-Torres, Isamu Daniel Cabrera-Takane, Patricia Bautista-Carbajal, Miguel Leonardo García-León, Daniel E. Noyola, María Susana Juárez-Tobías, Verónica Tabla-Orozco, Pedro Antonio Martínez-Arce, María del Carmen Espinosa-Sotero, Gerardo Martínez-Aguilar, Fabian Rojas-Larios, Luis Alfonso Salazar-Soto, Rosa María Wong-Chew

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Corrigendum: NLR, a convenient early-warning biomarker of fatal outcome in patients with severe fever with thrombocytopenia syndrome by Yuanyuan Wei, Yuanyuan Wei, Zilong Wang, Luyang Kang, Lingling He, Lingling He, Nan Sheng, Nan Sheng, Jiangfeng Qin, Jiangfeng Qin, Shuangshuang Ma, Honghai Xu, Lifen Hu, Guizhou Zou, Yufeng Gao, Yufeng Gao, Jiabin Li, Jiabin Li

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