Transmission of unfolded protein response—a regulator of disease progression, severity, and spread in virus infections by Vibhu Prasad

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Natural regulatory T cells increase significantly in pediatric patients with parasitic infections: Flow cytometry study by Nadeem Kizilbash, Nida Suhail, A. Khuzaim Alzahrani, W. Jamith Basha, Mohamed Soliman

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Comparison of Community-Acquired Pneumonia Requiring Admission to Hospital in HIV-and Non-HIV-Infected Patients by Claire Touchie, Thomas J Marrie

“…OBJECTIVE: To compare community-acquired pneumonia (CAP) in hospitalized human immunodeficiency virus (HIV)-infected patients with that in hospitalized non-HIV-infected patients by assessing presenting characteristics, etiology and outcomes.…”
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Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions. by Miguel Ángel Pérez-Castro, Hasier Eraña, Enric Vidal, Jorge M Charco, Nuria L Lorenzo, Nuno Gonçalves-Anjo, Josu Galarza-Ahumada, Carlos M Díaz-Domínguez, Patricia Piñeiro, Ezequiel González-Miranda, Samanta Giler, Glenn Telling, Manuel A Sánchez-Martín, Joseba Garrido, Mariví Geijo, Jesús R Requena, Joaquín Castilla

“…Our study aimed to explore the influence of a polyanionic cofactor in modulating strain selection and infectivity in de novo-generated synthetic prions. These results not only validate PMSA as a robust method for generating diverse bona fide recombinant prions but also emphasize the significance of cofactors in shaping specific prion conformers capable of crossing species barriers. …”
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Microbial Dynamics in Endodontic Pathology—From Bacterial Infection to Therapeutic Interventions—A Narrative Review by Klara Wieczorkiewicz, Anna Jarząbek, Estera Bakinowska, Kajetan Kiełbowski, Andrzej Pawlik

Subjects: “…endodontic infection…”
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Viral entry mechanisms: the role of molecular simulation in unlocking a key step in viral infections by Mariana Valério, Carolina C. Buga, Manuel N. Melo, Cláudio M. Soares, Diana Lousa

“…Viral infections are a major global health concern, affecting millions of people each year. …”
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Impact of Mandatory Preoperative Dental Screening on Infective Endocarditis in Patients Undergoing Surgical Valve Replacement by Lytfi Krasniqi, MD, Poul Erik Mortensen, MD, Emil Johannes Ravn, MD, Marlene Tofterup, MD, Henrik Nissen, MD, PhD, Christian Juhl Terkelsen, MD, PhD, DMSCi, Niels Holmark Andersen, MD, PhD, DMSCi, Ivy Modrau, MD, DMSCi, Kasper Stokbro, DDS, PhD, Jonas A. Povlsen, MD, PhD, Oke Gerke, MSc, PhD, DMSCi, Jesper Hallas, MD, DMSCi, Marie-Annick Clavel, DVM, PhD, Lars Peter Schødt Riber, MD, PhD, DMSCi, Jordi Sanchez Dahl, MD, PhD, DMSCi

“…Background: Guidelines recommend preoperative dental screening (PDS) prior to surgical valve replacement (SVR) to reduce risk of prosthetic valve infective endocarditis (IE). Nonetheless, limited data support these recommendations. …”
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Evaluation of the Tyrosine and Dopamine Serum Levels in Experimental Infected BALB/c Mice with Chronic Toxoplasmosis by Mehdi Mirzaeipour, Fattaneh Mikaeili, Qasem Asgari, Mohammad Nohtani, Sajad Rashidi, Mohammad Saleh Bahreini

“…Toxoplasma parasite alters the transduction of neurotransmitter signals and leads to changes in the level of brain neurotransmitters including tyrosine and dopamine, so behavior changes can occur in infected hosts. Based on this concept, this study was conducted for evaluation of the tyrosine and dopamine serum levels in infected mice with chronic toxoplasmosis. …”
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Seroprevalence Estimates of Q Fever and the Predictors for the Infection in Cattle, Sheep, and Goats in Nandi County, Kenya by J. Kiptanui, P. B. Gathura, P. M. Kitala, B. Bett

“…Q fever is an important worldwide zoonotic disease that affects almost all domestic animals, wildlife, and humans. The infection has both socio-economic and public health significance. …”
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Acute Pancreatitis Complicating Acute Hepatitis E Virus Infection: A Case Report and Review by Hemanta Kumar Nayak, Nitish L. Kamble, Nishant Raizada, Sandeep Garg, Mradul Kumar Daga

“…The identification of this unusual complication of Hepatitis E is important; however, the prognosis for patients with Acute Pancreatitis Complicating Acute Hepatitis E Virus Infection is good, and uncomplicated recovery with conservative treatment is expected.…”
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Severe pneumonia due to concurrent Legionella pneumophila and Acinetobacter baumannii infections: a case report by Xiaoming Yang, Zhongda Liu, Xiaojing Liu, Quan Li, Hui Huang, Yibo Wei, Tao Sun

“…Acinetobacter baumannii is a major pathogen responsible for hospital-acquired pneumonia, but it rarely causes serious infections in a community setting. Without prompt and appropriate treatments, infection from either of these two pathogens can cause a high mortality rate. …”
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Costs and Outcomes of Clostridioides difficile Infections in Germany: A Retrospective Health Claims Data Analysis by Katharina Schley, Kirstin Heinrich, Jennifer C. Moïsi, Dennis Häckl, Dominik Obermüller, Gordon Brestrich, Christof von Eiff, Thomas Weinke

“…Since no recent data were available from Germany on the medical costs and clinical outcomes of Clostridioides difficile infections (CDI), this study assessed the economic burden of CDI and all-cause mortality in adults in Germany. …”
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Clinical significance of Helicobacter pylori infection in iron-deficiency anemia: features of comprehensive treatment approach by I. V. Mayev, S. A. Kochetov

“…Presence of H. pylori infection and eradication control were carried out by urea breath test (Helic-test system). …”
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Seroprevalence of hepatitis E virus infection in blood donors from Piauí State, Northeast Brazil by João Paulo da Silva-Sampaio, Raniela Borges Sinimbu, Julia Trece Marques, Abilio Francisco de Oliveira Neto, Livia Melo Villar

“…This study demonstrated low prevalence of HEV infection in blood donors in this region.…”
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Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against <i>Klebsiella pneumoniae</i> Infection by Svetlana V. Dentovskaya, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Alena S. Kartseva, Tatiana A. Ivashchenko, Vladimir N. Gerasimov, Mikhail E. Platonov, Victoria V. Firstova, Andrey P. Anisimov

“…Although such structures are less naive than classical bacterial ghosts, they provide effective protection against infection by a hypervirulent strain of <i>K. pneumoniae</i> and can be recommended as candidate vaccines. …”
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Risk of Coronary Heart Disease among HIV-Infected Patients: A Multicenter Study in Brazil by Sandra C. Fuchs, Paulo R. Alencastro, Maria Letícia R. Ikeda, Nêmora T. Barcellos, Fernando H. Wolff, Ajácio B. M. Brandão, Ricardo A. A. Ximenes, Demócrito de B. Miranda-Filho, Heloísa Ramos Lacerda, Maria de Fátima P. M. de Albuquerque, Ulisses Ramos Montarroyos, Max W. Nery, Marilia D. Turchi

“…Cardiovascular disease has emerged as a crescent problem among HIV-infected population. This study aimed to determine the 10-year risk of coronary heart disease using the Framingham risk score among HIV-infected patients from three regions of Brazil. …”
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Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production by Brandon R. Scharpf, Hannah Ruetten, Jaskiran Sandhu, Kyle A. Wegner, Sneha Chandrashekar, Olivia Fox, Anne E. Turco, Clara Cole, Lisa M. Arendt, Douglas W. Strand, Chad M. Vezina

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Effective Binding of a Phosphatidylserine-Targeting Antibody to Ebola Virus Infected Cells and Purified Virions by S. D. Dowall, V. A. Graham, K. Corbin-Lickfett, C. Empig, K. Schlunegger, C. B. Bruce, L. Easterbrook, R. Hewson

“…Here, we demonstrate that PGN401 specifically binds to Ebola virus and recognizes infected cells. Our study provides the first evidence of phosphatidylserine-targeting antibody reactivity against Ebola virus.…”
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Investigating the Impact of HTNV Infection on the Gut Microbiota of Wild-Type and NLRX1 Knockout Mice by Wenjie Sun, Yaxin Ding, Ziyu Liu, Shiyuan Hou, Danni Sun, Ruixue Ma, Huarui Kang, Xiaohan Ma, Jiayu Wang, Hongrui Mu, Yunhua Lv, Tianle Gu, Qikang Ying, Fang Wang, Xingan Wu, Rongrong Liu

“…It is becoming increasingly clear that maintaining the equilibrium of gut microbiota homeostasis during viral infections, such as Hantaan virus (HTNV), is of paramount importance. …”
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Evaluation of prescribing practices and treatment failure for purulent skin and soft tissue infections in patients with obesity by Mackenzie L. Miller, Destiny M. Hughson, Noah D. Blower, Andrew P. Jameson, Lisa E. Dumkow

“…Key exclusion criteria were chronic infections, antibiotic treatment within the past 30 days, and suspected polymicrobial infections. …”
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