Modelling the immunopathogenesis of HIV-1 infection and the effect of multidrug therapy: The role of fusion inhibitors in HAART by Gesham Magombedze, Winston Garira, Eddie Mwenje

“…There is currently tremendous effort being directed at developingpotent, highly active antiretroviral therapies that can effectively control HIV-1 infection without the need for continuous, lifelong use of these drugs. …”
Get full text

Development and clinical assessment of a novel probiotic candy in the prevention of respiratory infections in asthmatic children by Rana Tafrishi, Hamid Ahanchian, Seyed ali Jafari, Abolfazl Pahlevanloo, Hamidreza Kianifar, Mohammadali Kiani, Nasrin Moazzen, Tahereh sadeghi, Peter D. Sly

Subjects: Get full text

Exploring the interplay between Eimeria spp. infection and the host: understanding the dynamics of gut barrier function by Pan Chen, Mujeeb Ur Rehman, Yanfeng He, Aoyun Li, Fuchun Jian, Longxian Zhang, Shucheng Huang

“…Numerous studies have also revealed that Eimeria-infected animals experience slower bone growth rates, inferior meat quality, reduced egg production and quality, as well as impaired growth and development. …”
Get full text

Innate Immune Effectors Play Essential Roles in Acute Respiratory Infection Caused by Klebsiella pneumoniae by Dong Liu, Zhifu Chen, Yue Yuan, Haiming Jing, Jintao Zou, Xiaoli Zhang, Xi Zeng, Weijun Zhang, Quanming Zou, Jinyong Zhang

“…However, the roles of these effectors are not clearly defined during Klebsiella pneumoniae (K. pneumoniae) respiratory infection. In the current study, we established an acute pneumonia model of K. pneumoniae respiratory infection in mice and confirmed that the injury was most severe 48 h post infection. …”
Get full text

The mRNA-1647 vaccine: A promising step toward the prevention of cytomegalovirus infection (CMV) by Adewunmi Akingbola, Abiodun Adegbesan, Olajumoke Adewole, Kolade Adegoke, Akpevwe Emmanuella Benson, Paul Ayomide Jombo, Sandra Uchechukwu Eboson, Victor Oluwasola, Ademola Aiyenuro

Subjects: Get full text

PPARγ Expression and Function in Mycobacterial Infection: Roles in Lipid Metabolism, Immunity, and Bacterial Killing by Patricia E. Almeida, Alan Brito Carneiro, Adriana R. Silva, Patricia T. Bozza

“…Although the significance of peroxisome proliferator-activated receptor gamma (PPARγ) activation by mycobacteria is not fully understood, recent findings are beginning to uncover a critical role for PPARγ during mycobacterial infection. Here, we will review the molecular mechanisms that regulate PPARγ expression and function during mycobacterial infection. …”
Get full text

A Descriptive Study of Nosocomial Infections in an Adult Intensive Care Unit in Fiji: 2011-12 by Keshni Naidu, Ilisapeci Nabose, Sharan Ram, Kerri Viney, Stephen M. Graham, Karen Bissell

“…Nosocomial infections in an intensive care unit (ICU) are common and associated with a high mortality but there are no published data from the Oceania region. …”
Get full text

Antibiogram Profile of Patients Having Urinary Tract Infection Treated with Most Commonly Used Antibiotics by Bilal Ahmad, Faleesha Gul, Said Hassan, Haseeba Arif, Amber Javaid, Shawkat Ali

Subjects: Get full text

Caring at the transition: success and financial barriers of fidaxomicin discharge prescriptions for inpatients with Clostridioides difficile infection by Ellen Earle, Jigar Mehta, Alexis Blecher, Matthew Shou Lun Lee

“…This retrospective cohort study evaluated the proportion of inpatients initiated and successfully discharged on fidaxomicin for Clostridioides difficile infection. Nearly, all patients (96.4%; 27/28) were able to obtain fidaxomicin to complete their treatment course, although there was variability in copays among patients with Medicare.…”
Get full text

Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula by Kaitlin N. DePrez, John Ferguson

Get full text

Canadian Hepatitis C Look-Back Investigation to Detect Transmission from an Infected General Surgeon by Meenakshi Dawar, Tammy L Stuart, Lamont E Sweet, Anne M Neatby, Lewis P Abbott, Anton P Andonov, Tom Wong, Robert Gervais, Rob Stirling

“…BACKGROUND: In February 2007, a general surgeon in Charlottetown, Prince Edward Island, tested positive for hepatitis C virus (HCV). The surgeon’s infection onset date could not be determined; however, episodic hepatic enzyme elevations were first detected in November 2004 and again in February 2007. …”
Get full text

Cardiovascular Risk Assessment: A Comparison of the Framingham, PROCAM, and DAD Equations in HIV-Infected Persons by Max Weyler Nery, Celina Maria Turchi Martelli, Erika Aparecida Silveira, Clarissa Alencar de Sousa, Marianne de Oliveira Falco, Aline de Cássia Oliveira de Castro, Jorge Tannus Esper, Luis Carlos Silva e Souza, Marília Dalva Turchi

“…This study aims to estimate the risk of cardiovascular disease (CVD) and to assess the agreement between the Framingham, Framingham with aggravating factors, PROCAM, and DAD equations in HIV-infected patients. A cross-sectional study was conducted in an outpatient centre in Brazil. 294 patients older than 19 years were enrolled. …”
Get full text

A Multiregion Discrete-Time Epidemic Model of Mycobacterium tuberculosis Infections: An Optimal Control Approach by Rachid Bouajaji, Hassan Laarabi, Mostafa Rachik, Abdelhadi Abta

Get full text

Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole by Yu’e Wu, Fangui Min, Jinchun Pan, Jing Wang, Wen Yuan, Yu Zhang, Ren Huang, Lixin Zhang

“…This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide and evaluate the antifungal efficiency of fluconazole. …”
Get full text

Bioclimatologie des infections cutanées mycosiques à Sfax (Centre-Est de la Tunisie) by Mounir Jarraya

“…The fungal infections are a major public health problem in Sfax (Central-East of Tunisia) because it affects a vulnerable population. …”
Get full text

Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay by Jun-Yuan Yang, Xiao-Yan Wang, Xue-Zhi Li

“…A viral model of HIV infection of CD4+ T-cells with virus released period is formulated, and the effect of this released period on the stability of the equilibria is investigated. …”
Get full text

The secreted host-cell protein clusterin interacts with PmpD and promotes Chlamydia trachomatis infection by Fabienne Kocher, Johannes H. Hegemann

Subjects: Get full text

Throat Colonization of Neonatal Nursery Staff by Ureaplasma urealyticum: an Infection Control or Occupational Health Consideration? by Joanne E Embree, Michelle Alfa, Joy Lertzman, Gloria Gray, Carlos Fajardo, Annalee Yassi

Get full text

Invasive Bacillus cereus Infection in a Renal Transplant Patient: A Case Report and Review by Susan John, John Neary, Christine H Lee

Get full text

Sofosbuvir-Based Therapies for Patients with Hepatitis C Virus Infection: Real-World Experience in China by Chengguang Hu, Guosheng Yuan, Junwei Liu, Huaping Huang, Yanyu Ren, Yinping Li, Xuefu Chen, Wei Li, Tao Wu, Hong Deng, Yanzhong Peng, Yong-Yuan Zhang, Yuanping Zhou

“…There is scarcity of data in literature regarding the treatment response to sofosbuvir- (SOF-) based therapies in Chinese patients with chronic Hepatitis C Virus (HCV) infection. The aim of this study was to evaluate the efficacy and safety of SOF-based regimens for chronic hepatitis C (CHC) patients without cirrhosis in a real-world setting in mainland China. …”
Get full text