Standardization in the management of gram-negative bloodstream infections after implementation of a clinical care guideline at a large academic, safety-net institution: a quasi-experimental study by Michael A. Deaney, Katherine C. Shihadeh, Alexandra Craig, Margaret M. Cooper, Paul D. Paratore, Timothy C. Jenkins

“… Abstract Objective: To evaluate the impact of implementing a clinical care guideline for uncomplicated gram-negative bloodstream infections (GN-BSI) within a health system. Design: Retrospective, quasi-experimental study. …”
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Is C-reactive protein sufficient to guide antimicrobial therapy for lower respiratory tract infections among children? Results from a stepped-wedge cluster randomized trial in Uganda. by Chris A Rees, Prashant Mahajan, Quique Bassat

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Inflammatory rheumatic diseases with onset after SARS-CoV-2 infection or COVID-19 vaccination: a report of 267 cases from the COVID-19 and ASD group by Laura Massaro, Annamaria Iagnocco, Florenzo Iannone, Corrado Campochiaro, Maria De Santis, Ilaria Cavazzana, Piero Ruscitti, Roberto Giacomelli, Rosario Foti, Lorenzo Dagna, Giovanna Cuomo, Giacomo De Luca, Francesco Caso, Ilenia Di Cola, Clodoveo Ferri, Vincenzo Raimondo, Francesco Ursini, Veronica Brusi, Giuseppe Varcasia, Roberta Pellegrini, Domenico Olivo, Giuseppe Murdaca, Carlo Selmi, Olga Addimanda, Erika Pigatto, Francesca Francioso, Rossella De Angelis, Jacopo Ciaffi, Luana Mancarella, Marcella Visentini, Francesca Motta, Virginia Caira, Alberto Lo Gullo, Caterina Naclerio, Elena Marchetti, Sebastiano Lorusso, Jessica Luppino, Roberta Foti, Massimo Reta

“…Despite the short follow-up period, IJD and PMR patients’ response to first-line therapy was favourable, with both groups achieving a drop in baseline disease activity scores of ~30% and ~70% respectively.Conclusion Our article reports the largest cohort published to date of new-onset IRD following SARS-CoV-2 infection or COVID-19 vaccines. Although causality cannot be ascertained, the spectrum of possible clinical manifestations is broad and includes IJD, PMR, CTD and vasculitis.…”
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Estimation of Prevalence of Hospital-Acquired Blood Infections among Patients Admitted at a Tertiary Hospital in Oman over a Period of Five Years: A Cross-Sectional Study by Marah El-Beeli, Yahya Al-Farsi, Abdullah Balkhair, Zakariya Al-Muharrmi, Mansoor Al-Jabri, Samir Al-Adawi

“…Data from developed/developed countries have shown that hospital-acquired blood infections (HA-BSIs) are one of the most severe nosocomial infections and constitute 20%–60% of hospitalization-related deaths. …”
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Epidemiology, Disease Severity and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Viruses Coinfection Seen at Egypt Integrated Acute Respiratory Infections Surveillance, 2020–2022 by Manal Fahim, Wael H. Roshdy, Ola Deghedy, Reham Kamel, Amel Naguib, Shymaa Showky, Nancy Elguindy, Mohammad Abdel Fattah, Salma Afifi, Amira Mohsen, Amr Kandeel, Khaled Abdelghaffar

“…We studied epidemiology, severity, and outcome of patients with SARS-CoV-2/Flu coinfection seen at Egypt’s integrated acute respiratory infections surveillance to better describe disease impact and guide effective preventive measures. …”
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Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…To describe liver imaging reporting and data system (LI-RADS) version 2018 and other MRI imaging features in intrahepatic mass-forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. Methods. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. …”
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Regulation of Paneth cell-specific genes in COVID-19 patients and SARS-CoV-2-infected mice by quantification of mRNA from exfoliated cells in stool samples by Gill Diamond, Erika L. Figgins, Denny Gao, Tanya O. Robinson, Kenneth Wilson, Jon D. Gabbard, Charles D. Anderson, Lalit Batra, Chithra Sreenivasan, Jian Zheng, Uyen Do, Braden Mulcahy, Lisa K. Ryan, Nathaniel McLaughlin, Anna H. Owings, Neha Dhaliwal, Haley B. Williams, T. Grant Wichman, Michelle Galeas-Pena, Sarah C. Glover

“…It also shows the coordinate regulation of these genes as a response to infection with SARS-CoV-2, possibly through viral pathogenesis, to increase infectivity in the gut.…”
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The Combinational Effect of Enhanced Infection Control Measures and Targeted Clinical Metagenomics Surveillance on the Burden of Endemic Carbapenem and Other β-Lactam Resistance Among Severely Ill Pediatric Patients by Athina Giampani, Maria Simitsopoulou, Maria Sdougka, Christos Paschaloudis, Emmanuel Roilides, Elias Iosifidis

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Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infections by Dana Unninayar, Emilia L. Falcone, Hugo Chapdelaine, Donald C. Vinh, Karina A. Top, Beata Derfalvi, Thomas B. Issekutz, Hélène Decaluwe, Anne Pham-Huy, Julia Upton, Stephen D. Betschel, Tamar Rubin, Sneha Suresh, Nicola A. M. Wright, Luis Murguía-Favela, Tatiana Kalashnikova, Lisa Barrett, Sharon Oldford, Marc-Andre Langlois, Corey Arnold, Manish Sadarangani, Tinghua Zhang, Tim Ramsay, Dina Yazji, Juthaporn Cowan, Juthaporn Cowan

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Management of a COVID-19 outbreak using a multidisciplinary approach and infection prevention control practices at a community living center in Veterans Administration Hospital, North Texas by Ikwo K. Oboho, John Hanna, Denisse Silva-Rodriguez, Angela Christie-Smith, Andrew Psenicka, Ampava Khongmongkhon, Marcus A. Kouma, Sherry Reid, Roger Bedimo

“…Methods: We describe resident characteristics and outcomes, and infection control practices implemented during 2 COVID-19 outbreak periods (January 12–February 15, 2022, June 28–July 14, 2023). …”
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Molecular Epidemiological Characteristics of <i>Staphylococcus pseudintermedius</i>, <i>Staphylococcus coagulans,</i> and Coagulase-Negative Staphylococci Cultured from Clinical Ca... by Sara Horsman, Julian Zaugg, Erika Meler, Deirdre Mikkelsen, Ricardo J. Soares Magalhães, Justine S. Gibson

Subjects: “…canine skin infections…”
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A vicious cycle of frailty and acute lower respiratory infection among community-dwelling adults (≥ 60 years): Findings from a multi-site INSPIRE cohort study, India. by Siddhartha Saha, Ritvik Amarchand, Rakesh Kumar, Aslesh O Prabhakaran, Prabu Rajkumar, Sumit Dutt Bhardwaj, Suman Kanungo, Radhika Gharpure, Kathryn E Lafond, Eduardo Azziz-Baumgartner, Anand Krishnan

“…We studied the relationship of frailty and acute lower respiratory infection (ALRI) among a multi-site cohort of community-dwelling older adults aged ≥60 years in India. …”
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A vicious cycle of frailty and acute lower respiratory infection among community-dwelling adults (≥ 60 years): Findings from a multi-site INSPIRE cohort study, India by Siddhartha Saha, Ritvik Amarchand, Rakesh Kumar, Aslesh O. Prabhakaran, Prabu Rajkumar, Sumit Dutt Bhardwaj, Suman Kanungo, Radhika Gharpure, Kathryn E. Lafond, Eduardo Azziz-Baumgartner, Anand Krishnan

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Effects of different-valent vaccines against human papillomavirus (HPV) to prevent persistent HPV16/18 infections and CIN2+ in women: a systematic review and network meta-analysis by Haiyue Wu, Lucia Li, Kun Fu, YuFei Shen, Yingnan Lu, Zexi Liao, Yingzhen Liu, Wenting Zha, Lisha Wu, Yu Zhang

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A phase I/II study of adoptive immunotherapy using donor liver graft-derived NK cell-enriched immune cells to prevent severe infection after liver transplantation by Masahiro Ohira, Yuki Imaoka, Koki Sato, Koki Imaoka, Tomoaki Bekki, Takuya Yano, Ryosuke Nakano, Hiroshi Sakai, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Junko Tanaka, Hideki Ohdan

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Influence of caffeic acid and Bacillus coagulans supplementation on growth, digestive enzymes, immune response, and antioxidant gene expression in common carp (Cyprinus carpio) and its resistance to Aeromonas hydrophila infection by Seyedeh Shiva Alavinejad, Mehdi Soltani, Seyed saeed Mirzargar, Poulin Shohreh, Ali Taherimirghaed

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Is There a Real Relationship between the Presence of Helicobacter pylori in Dental Plaque and Gastric Infection? A Genotyping and Restriction Fragment Length Polymorphism Study on Patient Specimens with Dyspepsia in Southwest Iran by Mojtaba Moosavian, Elyas Kushki, Tahereh Navidifar, Eskandar Hajiani, Mahdi Mandegari

“…Also, to verify a hypothetical mouth-to-stomach infection route, the enzymatic digestions of three genes of cagA, vacA, and ureAB in H. pylori strains isolated from dental plaques and stomach samples were compared for each same case. …”
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Expression Profiles of Differentially Expressed Circular RNAs and circRNA–miRNA–mRNA Regulatory Networks in SH-SY5Y Cells Infected with Coxsackievirus B5 by Jing Li, Heng Yang, Huaran Shi, Jihong Zhang, Wei Chen

“…However, the functions of circRNA in response to CVB5 infection remain unclear. In our research, RNA-seq was employed to analyze the expression profiles of circRNAs in SH-SY5Y cells with or without CVB5 infection. …”
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SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York: a retrospective cohort studyResearch in context by Tesleem K. Babalola, Sean A.P. Clouston, Zennur Sekendiz, Devi Chowdhury, Nicola Soriolo, Joseph Kawuki, Jaymie Meliker, Melissa Carr, Bruno R. Valenti, Ashley Fontana, Onix A. Melendez, Olga Morozova, Benjamin J. Luft

“…PASC was common in this cohort so we used a Poisson regression model to compute multivariable-adjusted Relative Risk (RR) for the association between risk of PASC and SARS-CoV-2 re-infection, severity, and vaccination status at first infection. …”
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Pasteurella multocida Non-Native Joint Infection after a Dog Lick: A Case Report Describing a Complicated Two-Stage Revision and a Comprehensive Review of the Literature by Lam Philip W, Andrea V Page

“…Prosthetic joint infections (PJIs) are commonly caused by pathogens such as Staphylococcus aureus and coagulase-negative staphylococci; however, other microbial etiologies and specific risk factors are increasingly recognized. …”
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