Rare Case of Aspergillus ochraceus Osteomyelitis of Calcaneus Bone in a Patient with Diabetic Foot Ulcers by Farhang Babamahmoodi, Tahereh Shokohi, Fatemeh Ahangarkani, Mojtaba Nabili, Elham Afzalian Ashkezari, Sosan Alinezhad

“…One of the major complications of the disease is foot ulcer that is prone to infection. The most common causes of infection which have been reported in these patients are bacteria and fungi such as Candida, Aspergillus, and Rhizopus species. …”
Get full text

The Role of Ursodeoxycholic Acid Administration During the COVID-19 Pandemic: A Questionnaire Survey by Cheng Zhou, Ran Jia, Jinqiu Yang, Tong Liu, Xiaoyan Liu, Lin Yang, Wenxia Zhao

“…The objective of this questionnaire was to assess the infection status in the COVID-19 pandemic since December in Henan Province, China, and the prevalence of infection in people who were taking ursodeoxycholic acid (UDCA) during this period. …”
Get full text

A Case Report of Complete Resolution of Auricular Mucormycosis in an 18-Month-Old Diabetic Child by Mariam Aljehani, Hatem Alahmadi, Mansour Alshamani

“…One of the most rare but deadly types of infectious fungal infection is Mucormycosis. All the cases reported with this type of infection are immunocompromised individuals. …”
Get full text

Characterization of Enterobacterales growing on selective CPE screening plates with a focus on non-carbapenemase-producing strains by Reut Efrati Epchtien, Elizabeth Temkin, Mor N. Lurie-Weinberger, Ophir Kastel, Alona Keren-Paz, David Schwartz, Yehuda Carmeli

“…Laboratory reporting of these MDR bacteria might be useful for guiding treatment and prophylaxis when indicated, as well as for infection control.IMPORTANCESelective screening plates for carbapenemase-producing Enterobacterales (CPE) are used to detect CPE carriers for infection control purposes. …”
Get full text

OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines by Nicola Cotugno, Alessandra Ruggiero, Veronica Santilli, Emma Concetta Manno, Salvatore Rocca, Sonia Zicari, Donato Amodio, Manuela Colucci, Paolo Rossi, Ofer Levy, Federico Martinon-Torres, Andrew J. Pollard, Paolo Palma

Get full text

Regulation of viral replication by host restriction factors by Ying Lin, Ying Lin, Ying Lin, Yun Zhu, Yun Zhu, Ling Jing, Ling Jing, Ling Jing, Xiaobo Lei, Xiaobo Lei, Zhengde Xie, Zhengde Xie

“…As obligate parasites, viruses rely on host cells to replicate, and host cells have developed numerous defense mechanisms to counteract viral infection. Host restriction factors (HRFs) are critical components of the early antiviral response. …”
Get full text

Recurrence of Asymptomatic COVID-19 after Recovery among Healthcare Workers by Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata

“…The RT-PCR assay confirmed the first and second infection episodes. All cases showed negative RT-PCR results in the period between two infection episodes. …”
Get full text

Study of pathogenicity of fowl pox and pigeon pox virus isolates recovered in Russian Federation by S. A. Pokhvalny, A. N. Spiridonov

“…The paper demonstrates results of the studies of pathogenicity of fowl pox virus (Chicken/Rus-Rjazan/ FPV/2009 isolate) and pigeon pox virus (Pigeon/Rus-Astrakhan/PGPV/2012 and Pigeon/Rus-Vladimir/ PGPV/2010 isolates) using cross-infection. The chicks were infected intraocularly and intranasally or in-tradermally and epidermally. …”
Get full text

Age-Dependent Differences in Systemic and Cell-Autonomous Immunity to L. monocytogenes by Ashley M. Sherrid, Tobias R. Kollmann

“…Host defense against infection can broadly be categorized into systemic immunity and cell-autonomous immunity. …”
Get full text

Motion – The Available Treatments for Hepatitis C Are Cost Effective: Arguments against the Motion by W Ray Kim

“…Hepatitis C is a prevalent infection in North America. However, the natural history of hepatitis C virus (HCV) infection in the general population is not fully understood. …”
Get full text

Listeria Rhombencephalitis Complicating Anti-TNF Treatment during an Acute Flare of Crohn’s Colitis by L. Stratton, G. R. Caddy

“…In those on multiple immunosuppressants, a diet similar to that followed in pregnancy may minimise risk of acquiring this infection. Clinicians must always have a high index of suspicion for opportunistic infection in such immunocompromised patients.…”
Get full text

Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei by Marija Krasiļņikova, Catarina A. Marques, Emma M. Briggs, Craig Lapsley, Graham Hamilton, Dario Beraldi, Kathryn Crouch, Richard McCulloch

Get full text

Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran by Marzeieh Haghbin, Salar Maani, Mohammad Aref Bagherzadeh, Ahmadreza Bazmjoo, Heshmatollah Shakeri, Ali Taghipour, Shahab Falahi, Azra Kenarkoohi, Milad Badri, Amir Abdoli

“…Reactivation of latent toxoplasmosis is the main cause of severe infection among immunocompromised patients, including patients with cancer. …”
Get full text

Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

“…Here, we demonstrated that vimentin, a host intermediate filaments protein, is dispensable for HCV infection in cell models but essential for simulated in vivo infection in differentiated hepatocytes. …”
Get full text

The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis by Louise Tzung-Harn Hsieh, Belinda S Hall, Jane Newcombe, Tom A Mendum, Sonia Santana Varela, Yagnesh Umrania, Michael J Deery, Wei Q Shi, Josué Diaz-Delgado, Francisco J Salguero, Rachel E Simmonds

“…The drivers of tissue necrosis in Mycobacterium ulcerans infection (Buruli ulcer disease) have historically been ascribed solely to the directly cytotoxic action of the diffusible exotoxin, mycolactone. …”
Get full text

Exosomes Derived from Schistosoma japonicum Cystatin-Treated Macrophages Attenuated CLP-Induced Sepsis in Mice by Feifei Huang, Yayun Qian, Huihui Li, Liang Chu, Chen Wan, Qili Shen, Qianqian Li, Xiuxiu Li, Xinyue Wu, Bin Zhan, Rui Zhou, Xiaodi Yang

“…Sepsis is a disease caused by multiple microbial infections resulting in multiple organ failure. Schistosoma japonicum secreted cystatin (Sj-Cys) is a strong immunomodulator that stimulates M2 macrophages and alleviates inflammatory damage caused by sepsis. …”
Get full text

Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling by Xixi Cui, Mingjie Chang, Yuqiong Wang, Jiayi Liu, Zenghui Sun, Qiyu Sun, Yundong Sun, Juchao Ren, Wenjuan Li

“…Therefore, our results show a novel METTL14-VAMP3-LC3C-c-Met signalling axis in the GC development mediated by H. pylori infection, which reveals a novel m6A epigenetic modification mechanism for GC and provides potential prognostic biomarkers for GC progression.…”
Get full text

Mechanisms of blaIMP-4 dissemination across diverse carbapenem-resistant clinical isolates by Ying Fu, Faye C. Morris, Stephanie C. Pereira, Xenia Kostoulias, Yan Jiang, Callum Vidor, Galain Williams, Yogi Srikhanta, Nenad Macesic, Yunsong Yu, Dena Lyras, Anton Y. Peleg

Get full text

COMPREHENSIVE TREATMENT OF PATIENTS WITH PROSTATITIS FROM THE VIEWPOINT OF MODERN REQUIREMENTS by H.V. Bachurin

“…Bacteriuria was revealed in 96 patients (81.3%), almost equally between the mono-infection (50 patients) and mixed infection (46 patients). …”
Get full text

Comparison of Culture, Cytotoxin Assay and Two Eia Tests with Clinical Diagnosis of Clostridium difficile-Associated Diarrhea by Marilyn Binning, Michael A John, Berend C Schieven, Thomas W Austin, Robert Lannigan, Zafar Hussain

Get full text