Theoretical impact of a bedside decision-making tool on antibiotic use for suspected neonatal healthcare-associated infection: an observational study by Lizel Georgi Lloyd, Mirjam Maria van Weissenbruch, Adrie Bekker, Cecilia Ferreyra, Birgitta Gleeson, Angela Dramowski

Subjects: “…Neonatal healthcare-associated infections (HAI)…”
Get full text

Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model by Elena Ufimtseva

“…The new ex vivo model system measuring functional input of individual granuloma cells to formation of granulomatous inflammatory lesions in mice with latent tuberculous infection has been developed and described in the current study. …”
Get full text

Co-Occurrence of SARS-CoV-2 Infection and Inactivated SARS-CoV-2 Vaccination among Healthcare Workers by Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata

“…The presented cases describe the concurrent SARS-CoV-2 infection and inactivated SARS-CoV-2 vaccination among eight healthcare workers (HCWs). …”
Get full text

Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections by Yan T, Wang Q, Ma C, Teng X, Gong Z, Chu W, Zhou Q, Liu Z

Subjects: “…incisional surgical site infection…”
Get full text

Increased Eligibility for Treatment of Chronic Hepatitis C Infection with Shortened Duration of Therapy: Implications for Access to Care and Elimination Strategies in Canada by Sergio M Borgia, Adenike Rowaiye

“…In hepatitis C virus (HCV) genotype 1 noncirrhotic patients with a baseline viral load of <6×106 IU/mL, treatment with sofosbuvir-ledipasvir can be shortened to eight weeks without compromising ≥95% efficacy. The number of HCV-infected patients in Ontario eligible for shortened therapy, and the associated cost savings, are unknown. …”
Get full text

Prevalence of soil-transmitted helminths infection and associated risk factors among residents of Jigjiga town, Somali region, Eastern Ethiopia. by Abdlmenur Alewi Sedo, Ahmed Zeynudin, Tariku Belay, Mekdes Mekonen Belay, Ahmed Mohammed Ibrahim, Mohamed Omar Osman, Ramadan Budul Yusuf, Abdifatah Abdulahi

“…<h4>Conclusion</h4>Jigjiga town had a low prevalence of STHs infections. Infrequent hand washing habits before meals, earthen floors, low wealth status, and no habit of treating drinking water were significant associated factors. …”
Get full text

Establishment of a Mutant Library for Infection Cushion Development and Identification of a Key Regulatory Gene in <i>Botrytis cinerea</i> by Maoyao Tang, Kexin Wang, Pan Zhang, Jie Hou, Xiaoqian Yu, Hongfu Wang, Yangyizhou Wang, Guihua Li

“…<i>Botrytis cinerea</i>, the grey mould fungus affecting over 1400 plant species, employs infection cushion (IC), a branched and claw-like structure formed by mycelia, as a critical strategy to breach host surface barriers. …”
Get full text

Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India by Kevin John John, Karthik Gunasekaran, John Davis Prasad, Divya Mathew, Sohini Das, N. Sultan, Asha Mary Abraham, Ramya Iyyadurai

Get full text

Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans. by Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte, Mona H X Liu, Jennifer D Cohen, Kashish Chetal, Ruslan Sadreyev, Alex J Tate, Taiowa A Montgomery, Gary Ruvkun

“…To test if Orsay viral infection down-regulates synMuv B gene activity, we infected a single synMuv A mutant with Orsay virus and found that a Muv phenotype could be induced. …”
Get full text

Metabolomic Profiling Reveals Potential Biomarkers and Prominent Features in HIV/AIDS Patients Co-Infected with SARS-CoV-2 by Xuan Yan, Xinyu Zhang, Wei Song, Tangkai Qi, Zhenyan Wang, Yang Tang, Jianjun Sun, Shuibao Xu, Junyang Yang, Jiangrong Wang, Jun Chen, Renfang Zhang, Li Liu, Yinzhong Shen

“…In this study, the aim is to analyze the metabolomic profiles of HIV/AIDS patients co-infected with SARS-CoV-2 and to identify biomarkers indicative of co-infection. …”
Get full text

Immunotherapy with IgY Antibodies toward Outer Membrane Protein F Protects Burned Mice against Pseudomonas aeruginosa Infection by Fatemeh Norouzi, Bahador Behrouz, Mahya Ranjbar, Seyed Latif Mousavi Gargari

“…Burn patients with multidrug-resistant Pseudomonas aeruginosa infections commonly suffer from high morbidity and mortality, which present a major challenge to healthcare systems throughout the world. …”
Get full text

HIV-1 Replication in HIV-Infected Individuals Is Significantly Reduced When Peripheral Blood Mononuclear Cells Are Superinfected with HSV-1 by Taneth Yamsuwan, Chintana Chirathaworn, Pokrath Hansasuta, Parvapan Bhattarakosol

“…Herpes simplex virus (HSV) can cause generalized infection in human immunodeficiency virus- (HIV-) infected patients leading to death. …”
Get full text

Recombinant Enolase of Trypanosoma cruzi as a Novel Vaccine Candidate against Chagas Disease in a Mouse Model of Acute Infection by Minerva Arce-Fonseca, María Cristina González-Vázquez, Olivia Rodríguez-Morales, Verónica Graullera-Rivera, Alberto Aranda-Fraustro, Pedro A. Reyes, Alejandro Carabarin-Lima, José Luis Rosales-Encina

“…In this study, we used the recombinant enolase from T. cruzi H8 strain (MHOM/MX/1992/H8 Yucatán) (rTcENO) and its encoding DNA (pBKTcENO) to immunize mice and evaluate their protective effects in an experimental murine model of acute phase infection. Our results showed that mice vaccinated with rTcENO or its encoding DNA were able to generate typical specific antibodies (IgG1, IgG2a, and IgG2b), suggesting that a mixed Th1/Th2 immune response was induced. …”
Get full text

Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. by Anna Smed-Sörensen, Cécile Chalouni, Bithi Chatterjee, Lillian Cohn, Peter Blattmann, Norihiro Nakamura, Lélia Delamarre, Ira Mellman

“…Influenza A virus (IAV) infection is normally controlled by adaptive immune responses initiated by dendritic cells (DCs). …”
Get full text

The incidence and characteristics of acute respiratory infection (ARI) after the earthquake in West Pasaman and Pasaman Districts, West Sumatra Province in 2022 by Isnaini, Fitry Yani Finny, Dianne Jurnalis Yusri, Mariko Rinang

“…In February 2022, an earthquake struck Pasaman City in West Sumatra and caused outbreaks of infectious diseases such as acute respiratory infections (ARI). Method: This study used an ecological design by collecting data on the population in West Pasaman and Pasaman Regency in 2022. 13 subjects in West Pasaman and 16 subjects in Pasaman were obtained. …”
Get full text

Relationship between renal ultrasonographic, CD4 cell count and proteinuria findings in HIV infected adult patients in Jos, Nigeria by P. M., Gwom, D., Atsukwei, E. D., Eze, E. O., Igoh, E. A., Gabkwe, M. D., Adams, K. M., Rabiu, I., Ezekiel

Get full text

Assessment of Knowledge, Attitude and Practices of Health Workers Towards Hepatitis B Virus Infection Prevention in Health Centers of Bushenyi District. by Byamukama, Julius

Subjects: Get full text

A Four-Year Study of Antibiotic Resistance, Prevalence and Biofilm-Forming Ability of Uropathogens Isolated from Community- and Hospital-Acquired Urinary Tract Infections in Southern Italy by Marilena Trinchera, Angelina Midiri, Giuseppe Mancuso, Maria Antonietta Lagrotteria, Carmelo Antonio De Ani, Carmelo Biondo

Subjects: “…hospital-acquired urinary tract infections (HA-UTI)…”
Get full text

Rapid inference of antibiotic susceptibility phenotype of uropathogens using metagenomic sequencing with neighbor typing by Amanda C. Carroll, Leanne Mortimer, Hiren Ghosh, Sandra Reuter, Hajo Grundmann, Karel Brinda, William P. Hanage, Angel Li, Aimee Paterson, Andrew Purssell, Ashley Rooney, Noelle R. Yee, Bryan Coburn, Shola Able-Thomas, Martin Antonio, Allison McGeer, Derek R. MacFadden

Subjects: Get full text