Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature by Zuhal Yesilbag, Asli Karadeniz, Fatih Oner Kaya

“…Primary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. …”
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Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada by Jorge L. Martinez-Cajas, Ann Jolly, Yanping Gong, Gerald Evans, Santiago Perez-Patrigeon, Bradley Stoner, T. Hugh Guan, Beatriz Alvarado

“…Abstract Background Longitudinal healthcare worker (HCW) cohorts throughout the COVID-19 pandemic provide a unique opportunity to study the relative contributions of various exposures to infection risk over time. This study aimed to examine how demographic, health, occupational, household and community factors influenced the SARS-CoV-2 infection risk in a cohort of HCWs in Southeastern Ontario, Canada, during the early pandemic and the Omicron waves. …”
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A Subgroup of Latently Mycobacterium tuberculosis Infected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens by Ralf Baumann, Susanne Kaempfer, Novel N. Chegou, Wulf Oehlmann, Ralf Spallek, André G. Loxton, Paul D. van Helden, Gillian F. Black, Mahavir Singh, Gerhard Walzl

“…Elevated antibody responses to Mycobacterium tuberculosis antigens in individuals with latent infection (LTBI) have previously been linked to an increased risk for progression to active disease. …”
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Brief communication: virological outcomes and dolutegravir resistance mutations in HIV-infected patients: a multicenter retrospective cohort study in Mozambique by Anna Maria Doro Altan, Noorjehan Majid, Stefano Orlando, Elton Uamusse, Marcia Rafael, Zita Sidumo, Giovanni Guidotti, Fausto Ciccacci

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The application of pigment-protein fraction from Nannochloropsis oculata on β-actin response of Cromileptes altivelis infected with viral nervous necrosis by Uun Yanuhar, Achmad Khumaidi

“…An outcome from gene transcription, the protein protects against pathogen infection, such as receptor clustering, antigen internalization, and regulating vesicle for antigen processing. ß - actin expression will determine the success of immune response of the organism. …”
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Interleukin 28B polymorphism impact on early HCV kinetics in HCV-infected liver transplant recipients undergoing antiviral therapy by V. E. Syutkin, V. P. Chulanov, I. V. Karandashova, V. A. Dolgin, A. O. Chugunov

“…Blood samples were screened for single nucleotide polymorphisms (SNP) near the IL28B genes (rs8099917 T ≥G and rs12979860 C>T) by kit «AmpliSens® Genoscreen-IL28B-FL» (CRIE) in 24 HCV-infected recipients. All the patients underwent pegylated interferon-alfa with (n=21) or without (n=3) ribavirin at least for 12 weeks.Results. …”
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Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer by Mingxiang Zuo, Xiaoxia Li, Shuang Liu, Bin Chen, Du Cheng

“…Combination of three sgRNAs targeting β-defensin gene demonstrated higher activation efficacy of β-defensin than any single sgRNA and combinations of any two sgRNAs, showing an efficient inhibition of virus infection and replication. The titer of vesicular stomatitis virus (VSV) in the cells treated with dCas9-sgRNA targeting β-defensin was reduced by about 100-fold compared to that of cells treated with dCas9-scramble sgRNA (dCas9-scr sgRNA). …”
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The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target by Reem Alharthi, Monica Sueiro-Olivares, Isabelle Storer, Hajer Bin Shuraym, Jennifer Scott, Reem Al-Shidhani, Rachael Fortune-Grant, Elaine Bignell, Lydia Tabernero, Michael Bromley, Can Zhao, Jorge Amich

“…To gain insight into Aspergillus fumigatus sulfur-related metabolism during infection, we used a NanoString custom nCounter-TagSet and compared the expression of 68 key metabolic genes in different murine models of invasive pulmonary aspergillosis, at 3 time-points, and under a variety of in vitro conditions. …”
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Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India by Rahul Chaurasia, Diptiranjan Rout, Shamsuz Zaman, Kabita Chatterjee, Hem Chandra Pandey, Abhishek Kumar Maurya

“…NAT yields include 18 HBV and 3 HCV yields, of which 17 HBV yields were occult infections and 1 was window period (WP) infection. All 3 HCV yields were WP infections. …”
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A fulminant case of JC virus encephalopathy supporting a novel syndrome associated with JC virus infection of cortical neurons by Matteo Ciocca, Marta Pirovano, Monica Lodi, Antonino Romeo, Vincenza Fetoni

“…Our case suggests that JCV infection should be considered even in immunocompetent patients presenting with unexplained cortical lesions and rapidly progressive encephalopathy.…”
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Exploring microRNA-Mediated Immune Responses to Soil-Transmitted Helminth and Herpes Simplex Virus Type 2 Co-Infections by Roxanne Pillay, Pragalathan Naidoo, Zilungile L. Mkhize-Kwitshana

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Expression of the transcription factor encoding gene <i>StTCP23</i> in potato plants infected with the tuber spindle viroid by N. V. Mironenko, A. S. Orina, N. M. Lashina, О. S. Afanasenko

“…‘Colomba’ with the PSTVd viroid NicTr-3 strain on the StTCP23 expression in infected plants.Materials and methods. Potato plants of cv. …”
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Type A Quadricuspid Aortic Valve Infective Endocarditis Complicated by Multiple Aortocardiac Fistulae: Case Report and Brief Literature Review by Amine Ghalem, Mohammed Bachrif, Anass Hbali, Mostapha Beghi, Nabila Ismaili, Noha El Ouafi

“…Aortocardiac fistulae (ACF) are exceptionally due to infective endocarditis; they are usually congenital, posttraumatic, or complicate aortic dissection. …”
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The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response by Thomas Daniel Kraemer, Orlando Daniel Quintanar Haro, Eugen Domann, Trinad Chakraborty, Svetlin Tchatalbachev

“…Infection of mouse RAW264.7 macrophages with a tcpF knock-out mutant led to elevated cytokine response compared to the isogenic wild type E. faecalis strain. …”
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Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Activation of GSK-3β occurred after GAS infection, and inhibition of GSK-3β reduced iNOS expression and NO production. …”
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A Catheter-Related Bloodstream Infection by Brevibacterium casei in a Child with Acute Myeloid Leukemia: Case Report and Literature Review by Fumihiro Ochi, Hisamichi Tauchi, Kyoko Moritani, Shinobu Murakami, Hitoshi Miyamoto, Mayo Ueda, Kozo Nagai, Minenori Eguchi-Ishimae, Mariko Eguchi

“…There are few formal reports of Brevibacterium casei infection and even fewer reports of CRBSI due to this Gram-positive rod. …”
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Determinants of Tuberculosis Infection among Adult HIV Positives Attending Clinical Care in Western Ethiopia: A Case-Control Study by Hatoluf Melkamu, Berhanu Seyoum, Yadeta Dessie

“…There has been a drastic rise of tuberculosis (TB) infection across the world associated with the pandemic occurrence of HIV/AIDS. …”
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Comment on “Long-Term Outcome of Immediate Versus Postponed Intervention in Patients With Infected Necrotizing Pancreatitis (POINTER)”: Multicenter Randomized Trial by Shuirong Lin, MD, Ziming Song, MD, PhD, Xi Yu, MD, Wenxuan Xie, MD,PhD, Shunli Shen, MD, PhD, Ming Kuang, MD, PhD

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Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. by Dominique Dorin-Semblat, Jean-Philippe Semblat, Romain Hamelin, Anand Srivastava, Marilou Tetard, Graziella Matesic, Christian Doerig, Benoit Gamain

“…This mutation strongly impairs infected erythrocytes adhesion by abolishing VAR2CSA translocation to the surface of infected erythrocytes. …”
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Transovarial infection in Aedes Aegypti: Correlational study on incidence of dengue hemorrhagic fever (DHF) at endemic area of Semarang city, Indonesia by Bela Novita Irneta, Martini Martini, Hadi Mochamad, Udiyono Ari, Yuliawati Sri, Hestiningsih Retno

“…There was a relationship between transovarial infection with the incidence of DHF (p= 0.043). This study provides information that Aedes aegypti transmit virus by transovarial infections, and the distribution of DHF has spatially related to transovarial infections.…”
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