Primary Stability of Self-Drilling and Self-Tapping Mini-Implant in Tibia of Diabetes-Induced Rabbits by Jea-Beom Park, Eun-Young Kim, Janghyun Paek, Yoon-Ah Kook, Do-Min Jeong, Il-Sik Cho, Gerald Nelson

“…After 4 weeks of diabetic induction, 48 mini-implants (24 self-tapping and 24 self-drilling implants) were placed on the tibia of 6 diabetic and 6 normal rabbits. …”
Get full text

Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats by Isaac A. Adedara, Amos O. Abolaji, Blessing E. Odion, Isioma J. Okwudi, Abiola A. Omoloja, Ebenezer O. Farombi

“…These findings suggest that undue exposure to 2,5-HD at environmentally relevant levels may impair liver and kidney functions through induction of oxidative stress.…”
Get full text

Effects of High Internal Phase Emulsion Gels Stabilized by Whey Protein-Pectin Complex on the Quality of Low-Fat Processed Cheese by LI Hongjuan, LI Zhen, REN Chuan, YUAN Yujing, LI Ke, QIU Xiaobao, LI Hongbo, YU Jinghua

“…An emulsion gel stabilized by a mixture of whey protein and pectin (WP) and an emulsion gel stabilized by a mixture of whey protein and glucan (WG) were prepared by an acid induction method. The functional properties of WP and WG emulsion gels with dispersed phase volume fractions of 35% and 75% (called WP35, WG35, WP75, and WG75) were evaluated and compared, and the efficiency of high internal phase emulsion gels as a fat replacer in replacing fat in low-fat processed cheese was further investigated. …”
Get full text

The epidermal lipid-microbiome loop and immunity: Important players in atopic dermatitis by Junchao Wu, Lisha Li, Tingrui Zhang, Jiaye Lu, Zongguang Tai, Quangang Zhu, Zhongjian Chen

“…The lipid-microbiome loop is substantially influenced by intense adaptive immunity which is triggered by abnormal loop activity and affects the loop's integrity through the induction of atypical lipid composition and responses to dysregulated epidermal microbes. …”
Get full text

AhR Activation Transcriptionally Induces Anti-Microbial Peptide Alpha-Defensin 1 Leading to Reversal of Gut Microbiota Dysbiosis and Colitis by Manikandan Palrasu, Khadija Kakar, Amarnath Marudamuthu, Hamida Hamida, Shruthi Thada, Yin Zhong, Shanieka Staley, Philip Brandon Busbee, Jie Li, Monica Garcia-Buitrago, Mitzi Nagarkatti, Prakash Nagarkatti

“…AhR directly targeted the dioxin response element 3 (DRE3) region on the α-defensin 1 promoter in IECs. AhR-mediated induction of α-defensin 1 in colitis mice reversed the gut microbial dysbiosis and alleviated colitis. …”
Get full text

WETLAND AND BIOCULTURAL HERITAGE REGENERATION THROUGH THEMATIC ECOLOGICAL TOURISM PRACTICE: THE CASE OF PATAN SUB-DISTRICT, KHUN TAN DISTRICT, CHIANG RAI, THAILAND by Siripen YIAMJANYA, Kannapat KANKAEW, Bussaba SITIKARN, Parinya NAKPATHOM, Ali Mohsin Salim Ba AWAIN, Teerarat JABJAINAI

“…This study investigates the initiative of community ecological tourism and proposes a framework of ecological tourism development. The inductive approach utilizes field survey, in-depth interviews, participatory observation, focus group discussion with key tourism partners. …”
Get full text

Phytochemical, Antioxidant and Mitochondrial Permeability Transition Studies on Fruit-Skin Ethanol Extract of Annona muricata by Wisdom O. Iyanda-Joel, Olusayo B. Ajetunmobi, Shalom N. Chinedu, Emeka E. J. Iweala, Oluwatobi S. Adegbite

“…In the absence of CaCl2 0.84 mg/mL concentration of ESA induced MMPT pore opening by 129% while the extracts showed no inhibitory activity in its presence. The induction fold corresponded with the concentrations of cytochrome c released. …”
Get full text

False-Negative CSF Cryptococcal Antigen with Cryptococcus gattii Meningoencephalitis in Southeastern United States: A Case Report and Literature Review by Shawn Esperti, Austen Stoelting, Andrew Mangano, Dveet Patel, Jilian Sansbury, Robert Sherertz

“…The patient was started on IV steroids, induction Amphotericin and Fluconazole, followed by maintenance oral Fluconazole. …”
Get full text

LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04 by Yong Wang, Lili Chen, Yonghui Gu, Ying Wang, You Yuan, Qiujian Zhu, Mingchao Bi, Shuyan Gu

“…Our findings indicate that the dysregulation of FEZF1-AS1 participates in the TGF-β2-induced proliferation and migration of human lens epithelial cells (HLECs), which might be achieved, at least in part, through the induction of FEZF1 expression.…”
Get full text

Early Activation of Pulmonary TGF-β1/Smad2 Signaling in Mice with Acute Pancreatitis-Associated Acute Lung Injury by Hamid Akbarshahi, Asha Sam, Chaolei Chen, Ann H. Rosendahl, Roland Andersson

“…We demonstrate that TGF-β1 levels in the lungs of mice with acute pancreatitis increase as early as 9 h after induction. We observed an increased expression of ALK-5 in acute pancreatitis at both 9 and 24 h. …”
Get full text

Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…For decades, high-dose methotrexate-based induction regimens have been the standard treatment for PCNSL and have significantly improved patient overall survival (OS). …”
Get full text

Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity by Dalia Ali, Elna P. Chalisserry, Muthurangan Manikandan, Rimi Hamam, Musaad Alfayez, Moustapha Kassem, Abdullah Aldahmash, Nehad M. Alajez

“…Global gene expression and signaling pathway analyses of differentially expressed genes revealed a strong enrichment of genes involved in adipogenesis and osteogenesis in romidepsin-treated BMSCs during induction into adipocytes or osteoblasts, respectively. …”
Get full text

Cytotoxic and Apoptotic Effects of Different Extracts of Artemisia turanica Krasch. on K562 and HL-60 Cell Lines by Zahra Tayarani-Najaran, Mahla Sareban, Atefeh Gholami, Seyed Ahmad Emami, Mahdi Mojarrab

“…Sub-G1 peak in the flow cytometry histogram of the cells treated with CH2Cl2 extract of A. turanica and cleavage of PARP protein confirmed the induction of apoptosis with CH2Cl2 extract. Taken together, the findings of the present work suggest the anticancer potential of CH2Cl2 extract of A. turanica on human leukemic cancer cell lines.…”
Get full text

<i>Garcinia brasiliensis</i> Leaves Extracts Inhibit the Development of Ascitic and Solid Ehrlich Tumors by Lucas Sylvestre Silva, Eduardo Cavallini, Rafael André da Silva, Monielle Sant’Ana, Ariane Harumi Yoshikawa, Thiago Salomão, Bianca Huang, Paula Craice, Luiz Philipe de Souza Ferreira, Heitor Pedro Della Matta, Cristiane Damas Gil, Maria de Lourdes Gomes Pereira, Ana Paula Girol

“…In relation to tumor-induced animals, morphological changes, plasma enzymes, inflammatory mediators and the induction of apoptosis were analyzed, in addition to histopathological studies, to evaluate the inhibition of tumor growth. …”
Get full text

Thiopurines Induce Oxidative Stress in T-Lymphocytes: A Proteomic Approach by Misbah Misdaq, Sonia Ziegler, Nicolas von Ahsen, Michael Oellerich, Abdul R. Asif

“…Furthermore, reactive oxygen species (ROS) assay results were consistent with a significant induction of oxidative stress by both TPMT knockdown and thiopurine treatments. …”
Get full text

Successful Treatment with Mycophenolate Mofetil and Tacrolimus in Juvenile Severe Lupus Nephritis by Tomoo Kise, Hiroshi Yoshimura, Shigeru Fukuyama, Masatsugu Uehara

“…Lupus nephritis (LN) of juvenile onset often has severe disease presentation. Despite aggressive induction therapy, up to 20% of patients with LN are resistant to initial therapy and up to 44% suffer a renal relapse. …”
Get full text

Soft Wireless Passive Chipless Sensors for Biological Applications: A Review by Mingguang Zhang, Mengyun Li, Wei Xu, Fan Zhang, Daojin Yao, Xiaoming Wang, Wentao Dong

“…External information is obtained by soft wireless passive sensors via the external coils based on electromagnetic induction. The purpose of this review paper is to outline the biological applications of soft wireless passive chipless sensors and provide a classification of wireless passive sensors and an overall explanation of the main work. …”
Get full text

Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats by Pablo Muñoz, Carolina Estay, Paula Díaz, Claudio Elgueta, Álvaro O. Ardiles, Pablo A. Lizana

“…Although the importance of DNA methylation-dependent gene expression to neuronal plasticity is well established, the dynamics of methylation and demethylation during the induction and expression of synaptic plasticity have not been explored. …”
Get full text

A Hybrid Short-Term Traffic Flow Multistep Prediction Method Based on Variational Mode Decomposition and Long Short-Term Memory Model by Qichun Bing, Fuxin Shen, Xiufeng Chen, Weijian Zhang, Yanran Hu, Dayi Qu

“…The prediction performance of the proposed hybrid model is investigated using inductive loop data measured from the north-south viaduct expressway in Shanghai. …”
Get full text

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis by Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi, Yoshihiro Tsuchiya, Hideaki Kamata, Fuminori Tokunaga, Kazuhiro Iwai, Tomoichiro Asano

“…In this process, oxidative stress contributes to the induction of several inflammatory cytokines including TNF-α and　IL-1β in macrophages, while, in hepatocytes, NF-κB reportedly induces the expressions of cell survival genes for protection from apoptosis. …”
Get full text