Differentiation of mesenchymal stem cells towards lens epithelial stem cells based on three-dimensional bio-printed matrix by Yufan Liu, Zuowei Wang, Tianju Ma, Yi Gao, Wenqian Chen, Zi Ye, Zhaohui Li

“…Here we bio-printed mesenchymal stem cells (MSCs) using a commonly used bioink sodium alginate-gelatin blends, and investigated the induction effect of MSC differentiation towards lens epithelial stem cells (LESCs) under a combination of biochemical cues and biophysical cues. …”
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Interleukin-1 Modulation of Human Placental Trophoblast Proliferation

“…These findings demonstrated that IL-1 regulates human trophoblast growth by induction of cell cycle delay and cell death.</p>…”
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Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis. by Neha Malhotra, Sangmi Oh, Peter Finin, Jessica Medrano, Jenna Andrews, Michael Goodwin, Tovah E Markowitz, Justin Lack, Helena I M Boshoff, Clifton Earl Barry

“…All 3 of these potent electrophiles react with thiols and treatment of Mtb cells with these agents followed by Mtb RNAseq showed that these natural products all induce profound thiol stress suggesting a rapid depletion of mycothiol. The induction of thiol-reactive mycotoxins through 3 different systems in response to exposure to Mtb suggests that fungi have identified this as a highly vulnerable target in a similar microenvironment to that of the caseous human lesion.…”
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Unravelling the transcriptomic dynamics of Hyphopichia pseudoburtonii in co-culture with Botrytis cinerea. by Evelyn Maluleke, Neil Paul Jolly, Hugh-George Patterton, Mathabatha Evodia Setati

“…At 48 h, the genes up-regulated highlight mitotic cell cycle activity and induction of filamentous growth, while in later stages, up-regulation of genes encoding high affinity transporters of sugars, copper and iron, as well as those involved in the retention and utilization of siderophore-iron was evident. …”
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Du réalisme dans l’analyse économique des conflits d’usage : les enseignements de l’étude du contentieux dans trois départements français (Isère, Loire-Atlantique, Seine-Maritime)... by Thierry Kirat, Romain Melot

“…The empirical analysis centres on three French departments. The empirical, inductive, and institutional methodology followed aims at a realistic understanding of conflicts such as the courts resolve them. …”
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Animal Models of Diabetic Retinopathy: Summary and Comparison by Angela Ka Wai Lai, Amy C. Y. Lo

“…They include pharmacological induction of hyperglycemia and spontaneous diabetic rodents as well as models of angiogenesis without diabetes (to compensate for the absence of proliferative DR symptoms). …”
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Bioconvective thermal estimation of radiative micropolar nanofluid with mass suction and variable Brownian diffusion: Cattaneo–Christov model by D. K. Almutairi

“…The variable role thermal conductivity, Brownian diffusivity and motile density have been incorporated. The flow induction is based on porous moving stretched surface in presence of mass suction effects. …”
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Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far by T. J. Moore, Heidi Abrahamse

“…In addition to substantial research already having been conducted on the in vitro differentiation of stem cells for the treatment of neurological repair, numerous strategies for the induction and culture of stem cells into terminal neural lineages have also been developed. …”
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Gastrointestinal Disturbances Associated with the Consumption of Sugar Alcohols with Special Consideration of Xylitol: Scientific Review and Instructions for Dentists and Other Hea... by Kauko K. Mäkinen

“…Adaptation may take place as a result of enzyme induction in the intestinal flora. Some of the literature on xylitol has been difficult to access by health-care professionals and will be reviewed here. …”
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The Extracellular Matrix Contributes to Mechanotransduction in Uterine Fibroids by Phyllis C. Leppert, Friederike L. Jayes, James H. Segars

“…In this review we present evidence that the stiffness of fibroid tissue has a direct effect on the growth of the tumor through the induction of fibrosis. Fibrosis has two characteristics: (1) resistance to apoptosis leading to the persistence of cells and (2) secretion of collagen and other components of the ECM such a proteoglycans by those cells leading to abundant disposition of highly cross-linked, disoriented, and often widely dispersed collagen fibrils. …”
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Role of Muramyl Dipeptide in Lipopolysaccharide-Mediated Biological Activity and Osteoclast Activity by Hideki Kitaura, Masahiko Ishida, Keisuke Kimura, Haruki Sugisawa, Akiko Kishikawa, Kazuhiro Shima, Saika Ogawa, Jiawei Qi, Wei-Ren Shen

“…LPS also induces osteoclast formation and pathological bone resorption; MDP enhances LPS induction of both processes. Furthermore, MDP enhances the LPS-induced receptor activator of NF-κB ligand (RANKL) expression and toll-like receptor 4 (TLR4) expression both in vivo and in vitro. …”
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Molecular Analysis of Activation-Induced Cytidine Deaminase Gene in Immunoglobulin-E Deficient Patients by Sergio Roa, Maria Isidoro-Garcia, Ignacio Davila, Elena Laffond, Felix Lorente, Rogelio Gonzalez-Sarmiento

“…Understanding how class switch recombination (CSR) is regulated to produce immunoglobulin E (IgE) has become fundamental because of the dramatic increase in the prevalence of IgE-mediated hypersensitivity reactions. CSR requires the induction of the enzyme AICDA in B cells. Mutations in AICDA have been linked to Hyper-IgM syndrome (HIGM2), which shows absence of switching to IgE as well as to IgG and IgA. …”
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Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense by Fanrui Kong, Zixuan Wang, Chuchu Zhang, Yihua Xiao, Muhammad Abdul Rehman Saeed, Weini Li, Akira Goto, Qingshuang Cai, Shanming Ji

“…We show that silencing of Cul3 leads to a decreased induction of antimicrobial peptides and high mortality in adult flies after bacterial infection. …”
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Unraveling the pathogenesis of bone marrow hematopoietic injury and the therapeutic potential of natural products by Jing Long, Hengzhou Lai, Yuqing Huang, Fengming You, Yifang Jiang, Qixuan Kuang

“…Key pathogenic mechanisms include aging, radiation damage, chemical induction, infection and inflammation, and cross-talk with non-hematopoietic diseases. …”
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IFN-β production induced by PRRSV is affected by GP3 quantity control and CLND4 interaction by Dexin Li, Xinyu Cui, Yingchao Li, Qin Zhang, Hongyan Gao, Youbo Li, Yanmeng Hou, Hongjie Yuan, Yihong Xiao

“…These findings highlight functional differences in GP3 under quantity control, which account for the variations in IFN-β induction during the early and late stages of infection. …”
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Chemometric Analysis of Elemental Fingerprints for GE Authentication of Multiple Geographical Origins by Lu Xu, Qiong Shi, Si-Min Yan, Hai-Yan Fu, Shunping Xie, Daowang Lu

“…The levels of 15 mineral elements in GE, including Zn, Cd, Co, Cr, Cu, Ca, Mg, Mn, Mo, Ni, Pb, Sr, Fe, Na, and K, were determined using inductively coupled plasma mass spectrometry (ICP-MS). …”
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Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression by Shankar Suman, Wendy K. Nevala, Alexey A. Leontovich, James W. Jakub, Liyi Geng, Sarah A. McLaughlin, Svetomir N. Markovic

“…Overall, our findings suggest a strong connection between melanoma secretory EVs and the induction of tumor-associated macrophages that facilitates the development of an immunosuppressive TME, supporting melanoma metastasis through regulation at both local and systemic levels.…”
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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance by Alessia Fidoamore, Loredana Cristiano, Andrea Antonosante, Michele d’Angelo, Erica Di Giacomo, Carlo Astarita, Antonio Giordano, Rodolfo Ippoliti, Elisabetta Benedetti, Annamaria Cimini

“…The response to this event is the induction of angiogenesis, a process mediated by hypoxia inducible factors. …”
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Herbal Substance, Acteoside, Alleviates Intestinal Mucositis in Mice by Daniel Reinke, Stamatiki Kritas, Panagiotis Polychronopoulos, Alexios L. Skaltsounis, Nektarios Aligiannis, Cuong D. Tran

“…C57BL/6 mice were gavaged daily with acteoside 600 μg for 5 d prior to induction of mucositis and throughout the experimental period. …”
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A Query on the Components and Aspects of Critical Assessment of Academic Textbooks with an Emphasis on the Principles of Planning and Organizing Educational Messages by Mohammadreza Nili Ahmad Abadi, Ali Dana

“…This is a qualitative library research in which the scientific resources such as books and articles have been studied inductively, and then, the topics were categorized and new criteria for critical assessment of textbooks were presented. …”
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