Static and Dynamic Experiment Evaluations of a Displacement Differential Self-Induced Magnetorheological Damper by Guoliang Hu, Wei Zhou, Mingke Liao, Weihua Li

“…In this study, a linear variable differential sensor (LVDS) based on the electromagnetic induction mechanism was integrated with a conventional MRD. …”
Get full text

Research of changes in electromagnetic parameters in controlled asynchronous special electric drives by V. Yu. Karandey, O. B. Popova, B. K. Popov, V. L. Afanasiev

“…The solved problem is spatial, since the distribution of electromagnetic induction in a coil of a given shape of an electromagnetic coil is determined. …”
Get full text

Principle of Virtual Work as Foundational Framework for Metamaterial Discovery and Rational Design by dell’Isola, Francesco, Misra, Anil

“…The current practice of mechanical analyses based upon moribund classical theories and experimental trial-error campaigns is caught in an inescapable vortex and illusion of inductive reasoning. The needed novel research paradigm is one in which the formulation of theoretical concepts precede their experimental validation. …”
Get full text

Comparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases by Celal Saritoy, Erol Karaaslan, Ahmet Selim Ozkan, Mehmet Tan, Ilham Gulcek

“…The input data were measured at pre-induction (T0), 5 minutes post-incision (T1), 20 minutes post-incision (T2), mastoidectomy during the tour (T3), cholesteatoma clearance (T4), grafting (T5), extubation (T6), 10 minutes post-extubation (T7), at the time of admission to the post-anesthesia care unit (PACU) (T8) and the 15th minute (T9) in PACU along with hemodynamic parameters values. …”
Get full text

Liver Regeneration after Partial Hepatectomy Is Not Impaired in Mice with Double Deficiency of Myd88 and IFNAR Genes by Javier Vaquero, Kimberly J. Riehle, Nelson Fausto, Jean S. Campbell

“…Though MyD88 is required for signaling by many TLRs, others signal via MyD88-independent pathways, leading to the induction of type I interferons (IFNs). Here, we assessed liver regeneration after partial hepatectomy (PH) in mice lacking both MyD88 and the type I IFN receptor (Myd88-IFNAR double-KO). …”
Get full text

(+)-Z-Bisdehydrodoisynolic Acid Enhances Basal Metabolism and Fatty Acid Oxidation in Female Obese Zucker Rats by William J. Banz, April D. Strader, Kolapo M. Ajuwon, Yuqing Hou, Cal Y. Meyers, Jeremy E. Davis

“…We also observed a marked reduction in respiratory quotient (RQ) along with a corresponding induction of hepatic AMPK in rodents provided (+)-Z-BDDA. …”
Get full text

The Strange Case: The Unsymmetric Cisplatin-Based Pt(IV) Prodrug [Pt(CH3COO)Cl2(NH3)2(OH)] Exhibits Higher Cytotoxic Activity with respect to Its Symmetric Congeners due to Carrier... by Elisabetta Gabano, Ilaria Zanellato, Giulia Pinton, Laura Moro, Mauro Ravera, Domenico Osella

“…The unexpected activity of 2 appears to be related to its peculiar cellular accumulation and not to a different rate of reduction or a different efficacy in DNA platination and/or efficiency in apoptosis induction. Although the exact mechanism of cell uptake is not fully deciphered, a series of naïve experiments indicates an energy-dependent, carrier-mediated transport: the organic cation transporters (OCTs) are the likely proteins involved.…”
Get full text

The Effects of Forodesine in Murine and Human Multiple Myeloma Cells by Liesbeth Bieghs, Jo Caers, Elke De Bruyne, Els Van Valckenborgh, Fiona Higginbotham, Karin Vanderkerken, Eline Menu

“…We found that after 48 hours of treatment with forodesine there was a slight dGTP increase in 5T33MM and RPMI-8226 MM cells associated with partial inhibition of proliferation and a limited induction of apoptosis. When investigating the pathways leading to cell cycle arrest and apoptosis, we observed an upregulation of p27, caspase 3, and BIM. …”
Get full text

An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders by Mohammed Alghamdi, Doaa Alasmari, Amjad Assiri, Ehab Mattar, Abdullah A. Aljaddawi, Sana G. Alattas, Elrashdy M. Redwan

“…A defect in the clearance system either in terms of efficiency or capacity may occur due to massive cell death, which may result in the accumulation and leakage of PAD enzymes and the citrullinated peptide from the necrotized cell which could be recognized by the immune system, where the immunological tolerance will be avoided and the autoimmune disorders will be subsequently triggered. The induction of autoimmune responses, autoantibody production, and cytokines involved in the major autoimmune diseases will be discussed.…”
Get full text

Pifithrin-μ sensitizes mTOR-activated liver cancer to sorafenib treatment by Jiarui Lv, Yanan Wang, Jiacheng Lv, Cuiting Zheng, Xinyu Zhang, Linyan Wan, Jiayang Zhang, Fangming Liu, Hongbing Zhang

“…Pifithrin-μ, an HSP70 inhibitor, synergized with sorafenib in the induction of ferroptosis in mTOR-activated liver cancer cells and suppression of TSC2-deficient hepatocarcinogenesis. …”
Get full text

Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries by Olivia Lenoir, François Gaillard, Hélène Lazareth, Blaise Robin, Pierre-Louis Tharaux

“…Renal function and histology were analyzed 10 weeks after diabetes induction with streptozotocin. Diabetic Hmox1+/− mice showed higher levels of albuminuria and blood urea compared to their wild-type diabetic littermates. …”
Get full text

RETRACTED: Environmental Impact of Pharmaceutical Pollutants: Synergistic Toxicity of Ivermectin and Cypermethrin by Davide Di Paola, Carmelo Iaria, Fabio Marino, Enrico Gugliandolo, Cristian Piras, Rosalia Crupi, Salvatore Cuzzocrea, Nunziacarla Spanò, Domenico Britti, Alessio Filippo Peritore

“…Combination of IVM at 100 μg L⁻¹ with CYP at 5 μg L⁻¹ exposure induced hatching delay and malformations at 96 hpf in zebrafish larvae as well as significant induction of cell death in zebrafish larvae. At the same time, the two single concentrations of IVM and CYP did not show a toxic effect on zebrafish development. …”
Get full text

Changes in Immunoreactivity of Sensory Substances within the Enteric Nervous System of the Porcine Stomach during Experimentally Induced Diabetes by Michał Bulc, Katarzyna Palus, Jarosław Całka, Łukasz Zielonka

“…Generally, the response to artificially inducted diabetes depended on the “kind” of enteric plexus as well as the stomach region studied. …”
Get full text

Theory of Elementary Contribution to Profit Transformation in the Concept of the Company and a Platform for the Realization of Islamic Banking by Sayed Amrollah Hoseini, Mohammad Zarei Mahmoudabadi

“…The present research has tried to answer this question And by studying the sayings of the jurists by the method of induction and data analysis, he has come to the conclusion that The concept of participation in the thought of Imami jurists has evolved and evolved And according to the latest belief, diffusion is not a condition for the realization of the company Rather, initial participation in profit is sufficient without mixing of properties. …”
Get full text

rre37 Overexpression Alters Gene Expression Related to the Tricarboxylic Acid Cycle and Pyruvate Metabolism in Synechocystis sp. PCC 6803 by Hiroko Iijima, Atsuko Watanabe, Junko Takanobu, Masami Yokota Hirai, Takashi Osanai

“…The transcripts of 6 genes (acnB, icd, ppc, pyk1, me, and pta) increased after 4 h of nitrogen depletion in the wild-type GT strain but the induction was abolished by rre37 overexpression. The repression of gene expression of fumC, ddh, and ackA caused by nitrogen depletion was abolished by rre37 overexpression. …”
Get full text

Growth and Survival of Acid-Resistant and Non-Acid-Resistant Shiga-Toxin-Producing Escherichia coli Strains during the Manufacture and Ripening of Camembert Cheese by M. P. Montet, E. Jamet, S. Ganet, M. Dizin, S. Miszczycha, L. Dunière, D. Thevenot, C. Vernozy-Rozand

“…Growth and survival of acid-resistant (AR) and non-acid-resistant (NAR) Shiga-toxin-producing Escherichia coli (STEC) strains were investigated during the manufacture and ripening of microfiltered milk Camembert cheeses. The induction of acid resistance of the STEC strains in cheeses was also studied. …”
Get full text

Improvement of Assemble-to-Order Model Processes With Process Mining: Dynamic Analysis and Hybrid Approaches by Ufuk Celik, Yuksel Yurtay

“…By combining direct flow graphs, inductive visual miner, and state chart workflows with a recursive algorithm, the proposed hybrid methodology identifies bottlenecks with repetitive works, analyzes variant impacts, and uncovers non-value-added activities. …”
Get full text

Non-thermal plasma as promising anti-cancer therapy against bladder cancer by inducing DNA damage and cell cycle arrest by Jojanneke Stoof, Zakaria Kalmoua, Ana Sobota, Ruud H. Brakenhoff, Marijke Stigter, Thang V. Pham, Sander R. Piersma, Alex Henneman, Tonny Lagerweij, Richard de Goeij-de Haas, R. Jeroen A. van Moorselaar, Connie R. Jimenez, Irene V. Bijnsdorp

“…PAS treatment exerts a potent cytotoxic effect through the production of intracellular reactive oxygen species, resulting in DNA damage and subsequent induction of G1 cell cycle arrest/senescence. This is induced via upregulation of cell cycle checkpoint signalling and DNA damage repair pathways using LC-M/MS-based phospho-proteomics. …”
Get full text

Evaluation of Salt Influence on Sugar Consumption by Suspension Cells Based on Spectroscopic Analysis by Ken-ichiro Suehara, Takaharu Kameoka, Atsushi Hashimoto

“…The cells were prepared for growth and although the cell did not grow under the induction period, the cell activation (start of sugar metabolism) was detected on the subtracted spectral behavior before the cell growth. …”
Get full text

G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication by Ryoya Sekine, Kouki Takeda, Tsukasa Suenaga, Satsuki Tsuno, Takumi Kaiya, Maki Kiso, Seiya Yamayoshi, Yoshihide Takaku, Shiho Ohno, Yoshiki Yamaguchi, Seiichi Nishizawa, Kazuhiro Sumitomo, Kazufumi Ikuta, Teru Kanda, Yoshihiro Kawaoka, Hidekazu Nishimura, Shusuke Kuge

“…Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its phosphorothioate-linked derivatives (G12(S)), rapidly entered cytoplasm and suppressed the propagation of human coronaviruses and influenza A viruses to between 1/100 and nearly 1/1000 of normal virus infectivity without cellular toxicity and induction of innate immunity. Moreover, G12(S) alleviated the weight loss caused by coronavirus infection in mice. …”
Get full text