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3561
Unveiling the antiurolithiatic potentiality of two benzene sulfonamide derivatives against ethylene glycol-induced renal calculi
Published 2025-02-01“…This division enabled a comparative analysis between rats with kidney stones and those without, offering insights into the effects of kidney stone induction on various physiological parameters and biochemical markers. …”
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3562
Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling
Published 2025-01-01“…According to database predictions, miR-142-5p, identified as a shared upstream molecule of TRPV1 and CDK5, exhibited downregulation following induction by NP. MiR-142-5p was shown to simultaneously bind to the mRNA of CDK5 and TRPV1, thereby inhibiting their expression. …”
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3563
Crack of a helicopter main rotor actuator attachment: failure analysis and lessons learned
Published 2013-10-01“…The accordance with the specification requirements about alloy composition was verified by quantitative elementary analysis through inductive coupled plasma spectroscopy (ICP); furthermore, semi-quantitative elementary analysis was locally verified by Energy dispersion spectroscopy X ray (EDS_RX). …”
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3564
Pien Tze Huang Attenuates Neuro-inflammatory Injury in BV2 Microglial Cells Induced by Lipopolysaccharide via Inhibition of TLR4/MAPK Signaling Pathway
Published 2021-02-01“…Then the protein expression of TLR4, ERK1/2, p-ERK1/2, p38, p-p38, JNK, p-JNK, COX-2, iNOS in BV2 microglial cells were detected by Western blot.Results:1) The result of MTT assay showed that PZH at 0.05-0.15 mg/mL concentration and LPS at 100 ng/mL concentration had no significant cytotoxicity on BV2 microglial cells (<italic>P</italic>> 0.05).2) The result of ELISA showed that the secretion of IL-6 was significantly increased in BV2 microglial cells induced by LPS compared with the normal control group (<italic>P</italic>< 0.001); compared with the LPS group, different concentrations of PZH significantly decreased the expression level of IL-6 in LPS-induced BV2 microglial cells (<italic>P</italic>< 0.05, <italic>P</italic>< 0.05, <italic>P</italic>< 0.01).3) The result of RT-qPCR showed that the transcriptional levels of IL-1β(<italic>P</italic>< 0.001), IL-6(<italic>P</italic>< 0.001) and TNF-α(<italic>P</italic>< 0.01) were significantly increased after the induction of LPS compared with normal controal group; different concentrations of PZH significantly inhibited the LPS-induced IL-1β(<italic>P</italic>< 0.05, <italic>P</italic>< 0.01, <italic>P</italic>< 0.001), IL-6(<italic>P</italic>> 0.05, <italic>P</italic>< 0.01, <italic>P</italic>< 0.001) and TNF-α(<italic>P</italic>< 0.01, <italic>P</italic>< 0.01, <italic>P</italic>< 0.001) mRNA upregulation.4) The result of Western blot showed that PZH significantly inhibited the LPS-induced TLR4/MAPK signaling pathway activation, and decreased the protein expressions of TLR4(<italic>P</italic>> 0.05, <italic>P</italic>< 0.05, <italic>P</italic>< 0.05), p-ERK1/2(<italic>P</italic>> 0.05, <italic>P</italic>< 0.05, <italic>P</italic>< 0.01), p-p38(<italic>P</italic>< 0.05, <italic>P</italic>< 0.01, <italic>P</italic>< 0.01), COX-2(<italic>P</italic>< 0.01, <italic>P</italic>< 0.01, <italic>P</italic>< 0.001) and iNOS(<italic>P</italic>< 0.01, <italic>P</italic>< 0.01, <italic>P</italic>< 0.01), but not p-JNK.Conclusion:PZH can significantly improve the LPS-induced neuro-inflammatory injury, which may be related to the inhibition of the activation of TLR4/MAPK signaling pathway.…”
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3565
The concerted actions of microRNA-29a and interferon-β modulate complete Freund's adjuvant-induced inflammatory pain by regulating the expression of type 1 interferon receptor, int...
Published 2025-03-01“…Results: Our results demonstrated elevated miR-29a expression (CFA 3 days: mean difference [95% confidence interval, CI]: 0.860 [0.657–1.062]; CFA 5 days: mean difference [95% CI]: 1.120 [0.917–1.322], P<0.001, n=6) and decreased IFNR1 expression (CFA 3 days: mean difference [95% CI]: −0.300 [−0.470 to −0.130]; CFA 5 days: mean difference [95% CI]: −0.330 [−0.515 to −0.145], P=0.004, n=6) from Days 3–5 post-CFA induction, with IFN-ß expression showing a significant increase from Day 2 (F [3.30, 16.5]=34.3 for factor time, P≤0.01, n=6). …”
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3566
Implementasi Program “Menjelajah Desa Menjemput Pajak” Pada Kantor Badan Pendapatan Kabupaten Langkat”
Published 2020-05-01“…Qualitative analysis in this study was conducted with an inductive logic approach. Based on the results of the research can be noted that the implementation of the program to explore the village picking up taxes in the District Revenue Board of Langkat is generally well-done. …”
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3567
Research of efficiency of ferrous metallurgy slag use in pavement base layers
Published 2024-12-01“…The analysis of other components was carried out on an atomic emission spectrometer with inductively coupled plasma after decomposition of the specimen with a mixture of inorganic acids. …”
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3568
Pattern of Professional Development of Human Resources of Knowledge-based Companies(Study case: Science and Technology Park of Iranian Research Organization for Science and Technol...
Published 2024-12-01“…Data analysis was done by content analysis method with inductive approach and coding. By coding the extracted interviews, 442 initial concepts, 149 indicators, 23 dimensions and 4 components were identified, of which the four main components were planning and policy making, teaching and learning, implementation and design and performance management To increase the internal validity of the study, member checking method was used. …”
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3569
概念為本跨領域課程發展之研究—以國際文憑組織中學階段課程為例 Concept-Based Interdisciplinary Curriculum Development in International Baccalaureate Schools in Taiwan– The International Baccalaureate Middle Years...
Published 2024-12-01“…In class, implementing a student-centered inductive inquiry model instead of a teacher-centered deductive lecturing model was crucial. …”
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3570
The pattern of elementary teachers' insight in online education, using foundational data theory
Published 2024-05-01“…In the current research, a systematic approach is used. This approach inductively uses a systematic set of procedures to develop a hypothesis in relation to a phenomenon. …”
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3571
How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland?
Published 2025-01-01“…Data were analyzed using thematic analysis with an inductive and deductive approach to be able to identify themes and codes (Braun & Clarke, 2022). …”
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3572
Whole-rock geochemistry and crystal chemistry of apatite at intrusive suites of the Qeynarjeh-Angouran district (west of Zanjan): an approach to the identification of skarn-causati...
Published 2024-10-01“…Whole-rock geochemical data has been carried out in the Geochemistry Laboratory of Istanbul University of Technology, by X-ray fluorescence (WDXRF) wavelength-based model S8 TIGER to detect the main oxide elements (in terms of wt.%) and inductively coupled plasma mass spectrometer (ICP-MS), ELAN DRC-e model for identification of minor and rare earth elements (in terms of ppm). …”
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3573
Providing a paradigmatic model of return on investment in the training of employees in the petrochemical industry
Published 2024-05-01“…This research was based on an empiricist philosophy, fundamental from the goal point of view, and with a deductive-inductive approach with a mixed research method. The research data in the qualitative part was collected through interviews with 17 management professors (theoretical experts) and managers of the petrochemical industry (experimental experts) who were selected by purposive sampling. …”
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3574
Designing and explaining the improvement model of women's employability capacity with emphasis on the 7th development plan
Published 2025-02-01“…Therefore, employability is the opportunity to obtain and maintain a job (Reilly et al, 2016).Research methodologyThe current research is based on qualitative research in the inductive paradigm and is applicable in terms of purpose. …”
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Designing a Forecasting Model and Evaluating the Strategic Cooperation between the Banking System and Fintech Startups using the Adaptive Neural Fuzzy Inference System (ANFIS)
Published 2024-06-01“…Materials and MethodsEmploying a grounded theory approach, this study formulates, rather than tests, theories through inductive reasoning. Initially, a semi-structured questionnaire was designed, informed by the literature, and administered to 14 experts with a minimum of a master's degree, and over a decade of experience in digital banking, startup management, and fintech. …”
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3576
A strontium isoscape of southwestern Australia and progress toward a national strontium isoscape
Published 2025-01-01“…The Sr was then separated by chromatography and its <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M5" display="inline" overflow="scroll" dspmath="mathml"><mrow class="chem"><msup><mi/><mn mathvariant="normal">87</mn></msup><mi mathvariant="normal">Sr</mi><msup><mo>/</mo><mn mathvariant="normal">86</mn></msup><mi mathvariant="normal">Sr</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="49pt" height="15pt" class="svg-formula" dspmath="mathimg" md5hash="e22ae2ee47cc1ea64b1ec348ae40208d"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="essd-17-79-2025-ie00003.svg" width="49pt" height="15pt" src="essd-17-79-2025-ie00003.png"/></svg:svg></span></span> ratio determined by multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS). …”
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Peer support for adult social care in prisons in England and Wales: a mixed-methods rapid evaluation
Published 2025-01-01“…Following this rapid analysis, a combination of inductive and deductive thematic analysis was used to conduct an in-depth analysis of findings. …”
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