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3481
Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats
Published 2018-01-01“…Collectively, our results revealed a tumor stimulatory effect (induction of tumor growth, progression, and metastasis) for exosomes derived from CSCs and an inhibitory effect for exosomes derived from MSCs. …”
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3482
Sodium Butyrate: A Multifaceted Modulator in Colorectal Cancer Therapy
Published 2025-01-01“…Nuclear condensation and fragmentation at higher NaB doses confirmed apoptotic induction. <i>Conclusions</i>: NaB can modulate critical apoptotic and cell cycle genes, disrupt tumor cell proliferation, and overcome resistance mechanisms associated with anti-apoptotic regulators such as <i>MCL-1</i>. …”
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3483
Preferences for and acceptability of long-acting HIV prevention products among pregnant and lactating women accessing health services in Kenya: a mixed method cross-sectional analy...
Published 2025-01-01“…We used descriptive statistics and categorical variables to summarize frequencies and proportions. Inductive and deductive content analytic approaches were used for in-depth interviews. …”
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3484
Long-term results of irritable bowel syndrome treatment
Published 2018-08-01“…Remission duration depend neither on clinical variant of disease, nor on the group of drugs applied for remission induction.…”
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3485
Performance of sewage sludge reuse in the manufacturing of fired bricks
Published 2023-07-01“…The aim of the study is to evaluate the properties of bricks made from sewage sludge, innovating an effective elimination of the urban sludge.METHODS: Measurements of sludge heavy metal concentrations are made with an inductively coupled plasma on a 63-micrometer fine particle fraction. …”
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3486
Enhancing elemental release and antibacterial properties of resin-based dental sealants with calcium phosphate, bioactive glass, and polylysine
Published 2025-01-01“…The element release over 4 weeks was measured using inductively coupled plasma-optical emission spectrometry (ICP-OES) (n = 3). …”
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3487
Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects
Published 2024-12-01“…However, this also makes the determination of high-PAS level of plasticity induction more challenging and calls for more research on the mechanism of action of high-PAS. …”
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3488
Presenting a Leadership Empowerment Model through Sense-making by Using the Cognitive and Behavioral Scripts
Published 2024-06-01“…This research is firmly grounded in an interpretive paradigm and is classified under qualitative methodologies, employing an inductive approach that also incorporated a retrospective analysis to deepen the understanding of the underlying themes. …”
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3489
Perspectives of Hispanic and Latinx Community Members on AI-Enabled mHealth Tools: Qualitative Focus Group Study
Published 2025-02-01“…We developed a qualitative codebook using deductive and inductive methods and then coded deidentified transcripts using the constant comparison method. …”
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3490
Analyzing the Influence of Managerial Traits and Financial Strategies on Corporate Risk-taking in the Tehran Stock Exchange
Published 2024-01-01“…In terms of the reasoning method, this research is a type of inductive research that uses the observation of parts of the society (sample) to present a model for the whole society. …”
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3491
Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice
Published 2025-01-01“…Assessments included magnetic resonance imaging (MRI), mechanical hyperalgesia tests, and inductively coupled plasma mass spectrometry to measure gadolinium levels. …”
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3492
Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study
Published 2025-02-01“…Recordings were professionally transcribed for thematic analysis with a mixed deductive and inductive framework, using Atlas.ti. Patients were surveyed about their interactions and satisfaction with peers. …”
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3493
Presenting a Model for Color Effectiveness in Marketing Using Consumer Neuroscience: A Sequential Exploratory Mixed-Methods Approach
Published 2023-12-01“…The research approach, in the qualitative phase, was inductive, and the research strategy was the classic grounded theory or Glaser approach. …”
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3494
Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods
Published 2025-01-01“…MethodsEvaluation methods included descriptive statistics, receiver operating characteristic (ROC) curve analysis, confusion matrices, Cohen κ, accuracy, specificity, precision, sensitivity (recall), F1-score harmonic mean, and the Matthews correlation coefficient. An inductive, iterative approach to content analysis of the data was used to obtain manual sentiment codes. …”
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3495
Designing a Conceptual model for Evaluating the Performance of Software Developers in Fintech Organizations
Published 2024-11-01“…Consequently, this research endeavors to identify and analyze the effective components for evaluating the performance of software developers in fintech organizations.MethodsThis research examines the lived experiences of software developers within the framework of an interpretative paradigm using an inductive and strategic phenomenological approach. …”
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3496
“I believe it when there is an expert next to me:” a qualitative analysis on the perceptions and experiences of pregnant women to self-monitor blood pressure in Lombok, Indonesia...
Published 2025-02-01“…Interviews were double transcribed in Bahasa Indonesia and translated to English for thematic analysis using inductive and deductive approaches. Results We enrolled a total of 71 pregnant women, across 11 FGDs and conducted 15 IDIs with participants who used the smartphone for SMBP. …”
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3497
Relevant Elements of Standardisation of Federation’s Advisory Programs for Voluntary Sports Clubs
Published 2025-01-01“…In line with the exploratory research design, data was analysed utilizing an inductive three-step coding process (Urquhart, 2023), and the emerging concepts were then structured along the “critical interfaces” identified by Klenk et al. (2017). …”
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3498
Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3
Published 2025-02-01“…The mechanism of anticancer effect of F12 (AAEAE) on cancer cell lines included induction of apoptosis, LDH leakage, and up regulation of gene expression levels of Caspase 3, Caspase 9, P53, and down regulation of BcL2 of all three cell lines. …”
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3499
Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress
Published 2020-12-01“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca<sup>2+</sup>concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic><0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic><0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic><0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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3500
Effect of General Anesthesia Combined with Transversus Abdominis Plane Block on Postoperative Sleep Disorders in Elderly Patients Undergoing Gastrointestinal Tumor Surgery: A Prosp...
Published 2025-01-01“…The group GA received the sedation-aspiration complex general anesthesia regimen, while the group GT underwent bilateral transversus abdominis plane blocks (TAPB) after the same induction of anesthesia. Group GA was injected bilaterally with equal amounts of saline in the same way. …”
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