Analysis of the Concentration of Heavy Metals in Khat Grown in Meru County and the Assessment of Their Associated Health Risks by Albert M. Oyugi, Joshua K. Kibet, John O. Adongo

“…Therefore, the motivation behind this contribution is to determine the levels of six heavy metals, namely, cadmium (Cd), copper (Cu), chromium (Cr), lead (Pb), iron (Fe), and nickel (Ni) in consumable Meru khat samples, compare these levels with the permissible limits of World Health Organization (WHO) in order to predict associated health risks, and to estimate the noncarcinogenic risks of these metals by total health quotient (THQ) and health index (HI) on khat consumers. 1.0 g of dry ground khat samples was digested in 0.05 M HCl and allowed to stand for 5 hours before being analyzed for heavy metals using inductively coupled plasma atomic emission spectroscopy (ICP-AES). …”
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The Presence of Antineutrophil Cytoplasmic Antibodies and Antiphospholipid Antibodies in Patients with Severe Acute Respiratory Syndrome Coronavirus 2: A Case-Control Study among S... by Mohammed Shams Aldeen, Musa Logman Masaad, Ayman Azhary, Abdulomez Suliman, Mohammed Ahmed Alziber, Motasim MohammedAhmed, Farag Alla Mohamed Aman, Salahaldeen Ismail, Nadir Abuzeid, Abdualmoniem O. Musa, Samuel Tekle Mengistu, Mohammed Elfatih Hamida

“…Patients infected with COVID-19 are at an increased risk for thrombosis, suggesting a possible role of COVID-19 in the induction of coagulopathy. This study aimed to investigate the presence of prothrombotic antineutrophil cytoplasmic antibodies (ANCA) and antiphospholipid antibodies (aPLs) in the course of COVID-19 infection and to correlate these markers with severity and fatality, suggesting that COVID-19-induced autoimmune thrombosis is a possible axis in the inflammatory circuit of this infection. …”
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Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model by I. P. Gileva, S. N. Yakubitskiy, I. V. Kolosova, S. N. Shchelkunov

“…The therapeutic potential of TNF-BD was studied using an experimental model of LPS-induced septic shock. After septic shock induction, several doses of recombinant TNF-BD were injected and the mortality of experimental animals was observed during 7 days. …”
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Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor by Rebecca Winkler, Hong Lu

“…Literature and data mining found abnormal induction of chemokine (C-X-C motif) ligand 1 (CXCL1) and CXCL8 and down-regulation of CXCL2 in inflammatory liver diseases. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…Furthermore, it discusses the role of Clec9a in the induction and functional activation of Clec9a+ cDC1s, with a particular focus on addressing the challenges related to off-target effects and immune tolerance in the development of tumor vaccines. …”
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Qingfei Tongluo Mixture Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis through mTOR-Dependent Autophagy in Rats by Shuyu Ge, Zhenghong Guo, Ting Xiao, Pingping Sun, Bo Yang, Yin Ying

“…Male SD rats were randomly divided into the following groups: control, model, CQ + QFTL (84 mg/kg chloroquine (CQ) + 3.64 g/kg QFTL), QFTL-L, M, H (3.64, 7.28, and 14.56 g/kg, respectively) and pirfenidone (PFD 420 mg/kg). After induction modeling and drug intervention, blood samples and lung tissue were collected for further detection. …”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…The aqueous leaf extract of CA was administered orally and daily at 400, 600 and 800mg/kg BW from 7days after induction of diabetes and lasted for 12 weeks, while the normal control and diabetic control rats received regular diet and HFD respectively. …”
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Health-care resource use and costs associated with inflammatory bowel disease in northwest London: a retrospective linked database study by Zia UI-Haq, Luiz Causin, Tahereh Kamalati, Durgesh Kahol, Trishan Vaikunthanathan, Charlotte Wong, Naila Arebi

“…Conclusions Higher health-care resource use and costs were observed with active disease, which underscores the importance of early induction and maintenance of remission in UC and CD. …”
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Experience, access and utilisation of fertility care for infertile men within the biomedical sector in urban Bangladesh: protocol for a qualitative study by Papreen Nahar, Gitau Mburu, Sohana Shafique, Priya Satalkar-Götz, Foyjunnaher Sultana

“…Service availability will be documented by creating a list of fertility clinics and cataloguing services offered in a selection of these clinics. Both inductive and deductive thematic analysis will be used.Ethics and dissemination The study has been reviewed and approved by the Brighton and Sussex Medical School’s Research and Governance Ethics Committee (RGEC: ER/BSMS9E3G/1), Institutional Review Board of icddr,b (International Centre for Diarrhoeal Disease Research, Bangladesh) and the WHO Ethics Review Committee (WHO ERC, AID: A66040). …”
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Aerodynamic optimization of small diffuser Augmented Wind Turbines: A differential evolution approach by Turan Dias Oliveira, Luzia Aparecida Tofaneli, Alex Álisson Bandeira Santos

“…A new expression for the correction of thrust coefficients for high values of axial induction factor is proposed, so that it is suitable for the evaluation of turbines with and without diffusers. …”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…The aqueous leaf extract of CA was administered orally and daily at 400, 600 and 800mg/kg BW from 7days after induction of diabetes and lasted for 12 weeks, while the normal control and diabetic control rats received regular diet and HFD respectively. …”
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Efficacy of continuous intravenous infusion of lidocaine on postoperative sore throat after laryngeal mask insertion: a randomized controlled trial by Jianxin Jiang, Jimin Wu, Shuqi Shi, Xiaoli Dong, Jiaxiang Yin, Yini Wu

“…Methods In this prospective trial one hundred and sixty general anesthesia surgery patients (20 to 60 years) using laryngeal mask airway were randomly divided into control group (Group C, saline as placebo), lidocaine gel group (Group LG, lidocaine gel applied to the surface of the laryngeal mask), single intravenous lidocaine group (Group SL, intravenous lidocaine 1.5 mg/kg at induction of anesthesia) and continuous infusion of lidocaine group (Group CL, a bolus of 1.5 mg/kg, followed by an infusion of 2 mg/kg/h until the end of the surgical). …”
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Development of Fermentation-induced Soymilk Gel: Effects of Different Lactic Acid Bacteria on the Physicochemical Characteristics by Fatemeh Rahmani, Ali Moayedi, Marteza Khomeiri, Mahboobeh Kashiri

“…In this study, the performance of three proteolytic lactic acid bacteria in the induction of soymilk gelation was compared and their effects on the physicochemical properties of resulting gels were investigated. …”
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The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors by Sahar Sadat Sedeighzadeh, Hamid Galehdari, Mohammad Reza Tabandeh, Mehdi Shamsara, Ali Roohbakhsh

“…Exposure to AEA (10 μM, 24 h) before or after inflammation induction downregulated the expression of inflammasome components and attenuated inflammasome activation as demonstrated by cleavage of caspase 1 and matured IL-1β secretion, although AEA pretreatment showed more reducing effects on the inflammasome activation. …”
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The experience of living with human immunodeficiency virus among adolescents at Felege Hiwot Comprehensive Specialized Hospital Bahir-Dar, Northwest Ethiopia, A phenomenological st... by Bazezew Asfaw Guadie, Minyichil Birhanu Belete, Meseret Mekuriaw Beyene, Ayalew Kassie Melese, Tarik Yenew Tessema, Yinager Workineh

“…To demonstrate findings, the inductive thematic analysis technique was applied using illustrative quotes. …”
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What are the training and support needs for homelessness hostel staff supporting older residents with memory and cognitive problems? A qualitative study by Luna Zalc, Sophie N. Gaber, Penny Rapaport

“…Methods In this qualitative study, we conducted inductive reflexive thematic analysis of semi-structured interviews with health and social care practitioners (n = 17) and hostel staff and managers (n = 15). …”
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The Anti-Inflammatory Effect of Chenopodium Murale in Comparison to Salvia Frigida on Atopic Eczema by Zahraa Y. Hassan, Tuka Y. Hassan, Ahmed Y. Kanany

“…Fifty mice were included in the study, subdivided equally into five subgroups [control, induction, Tacrolimus-1%, Phytosterol-3%, and Phenolic-5%]. …”
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Review on the Injury and Repair Mechanism of Skeletal Muscle Contusions by LIN Jianping, WANG Hao, GUO Mingling, WANG Shizhong, CHEN Shaoqing

“…As for the mechanism of autophagy in the repair of SMC, in addition to the induction of excessive ERS, it has been reported that SMC induces insufficient oxygen supply to local tissues, promotes the production of a large number of ROS or activation of AMPK signal pathway, and then induces mitochondrial autophagy, which maintains the stability of mitochondria and saves energy consumption, so as to achieve the purpose of promoting repair after SMC. …”
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NETosis Secondary to the Use of Levamisole-Adulterated Cocaine: A Likely Underlying Mechanism of Vasculopathy by Manuela Osorio, Isabel Velásquez, Ruben Vargas, Adriana Vanegas-García, Mauricio Rojas, Gloria Vásquez, Carlos Muñoz-Vahos

“…The involvement of calcium and muscarinic receptors in cell death induction was evaluated in parallel experiments carried out in the presence of 1,2-bis (o-aminophenoxy) ethane-N, N, N′, N′-tetraacetic acid (BAPTA) and hyoscine butylbromide (HBB), their respective inhibitors. …”
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Combination Therapy with Platelet-Rich Plasma and Epidermal Neural Crest Stem Cells Increases Treatment Efficacy in Vascular Dementia by Somayeh Akbari, Masoud Haghani, Mojtaba Ghobadi, Etrat Hooshmandi, Afshin Borhani Haghighi, Mohammad Saied Salehi, Sareh Pandamooz, Negar Azarpira, Afsoon Afshari, Shahrbanoo Zabihi, Marzieh Nemati, Mahnaz Bayat

“…Treatment with ESC alone and ESC + PRP showed similar improvements in spatial memory and LTP induction, with associated upregulation of PSD-95 and downregulation of GSK-3β. …”
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