Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer by Jenny Ling-Yu Chen, Chun-Kai Pan, Li-Cheng Lin, Yu-Sen Huang, Tsung-Hsuan Huang, Shu-Jyuan Yang, Sung-Hsin Kuo, Yu-Li Lin

“…Adding ICI therapy further enhanced local antitumor effects, reducing the metastatic lung tumor burden and remodeling the tumor microenvironment through immunogenic cell death induction and enhanced immune cell infiltration. Triple therapy increased immune cell infiltration in distant non-irradiated lung tumors and stimulated the generation of protective T-cell immunity in splenocytes. …”
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Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice by Chu X, Ge Y, Geng C, Cao P, Wei P, Fu B, Deng Z, Li Y, Zhao G

“…An acute epilepsy model was established in mice by kainic acid induction. The neuronal damage, microglial activation, inflammatory responses, and functional changes were determined by TUNEL assays, immunohistochemistry, quantitative real-time polymerase chain reaction and behavioral tests. …”
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Exploiting gasdermin-mediated pyroptosis for enhanced antimicrobial activity of phage endolysin against Pseudomonas aeruginosa by Dorota Kuc-Ciepluch, Karol Ciepluch, Daria Augustyniak, Grzegorz Guła, Barbara Maciejewska, Artur Kowalik, Ewelina Jop, Zuzanna Drulis-Kawa, Michał Arabski

“…We assume that leveraging pyroptosis induction in monocytic cells to augment the bactericidal activity of endolysins may be limited.IMPORTANCERecombinant GSDMDNterm protein was able to efficiently permeabilize P. aeruginosa outer membranes and increase endolysin activity against bacteria, producing either long LPS O-chains or lack them entirely. …”
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Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study by Titilola I Yakubu, Poonamdeep Jhajj, Samantha Pawer, Nicholas C West, Shazhan Amed, Tricia S Tang, Matthias Görges

“…A thematic analysis following an inductive and iterative process was performed to develop themes and subthemes from the collected information. …”
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Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI by Yu Shi, Shimin Huang, Hongrui Zhan, Yaping Wang, Yanyan Zeng, Guiyuan Cai, Jianming Yang, Wen Wu

“…We designed this study to explore the personality differences of functional magnetic resonance imaging (fMRI) signals in placebo response and nocebo response by using psychophysiological interaction (PPI) analysis. 30 healthy subjects underwent conditioning induction training to establish expectations of placebo effect and nocebo effect, and then, all subjects completed the following experimental procedures: (1) baseline scanning, (2) acute pain model establishment, (3) pain status scanning, and (4) pseudorandom scanning of block design of placebo response or nocebo response. …”
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The Role of Dendritic Cells in Adaptive Immune Response Induced by OVA/PDDA Nanoparticles by Daniele R. Pereira, Yunys Pérez-Betancourt, Bianca C. L. F. Távora, Geraldo S. Magalhães, Ana Maria Carmona-Ribeiro, Eliana L. Faquim-Mauro

“…<b>Conclusions</b>: The data showed the central role of DCs in the induction of antigen-specific immune response by OVA-PDDA-NPs, thus proving that these NPs are a potent adjuvant for subunit vaccine design.…”
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Barriers and Facilitators to User Engagement and Moderation for Web-Based Peer Support Among Young People: Qualitative Study Using the Behavior Change Wheel Framework by Ananya Ananya, Janina Tuuli, Rachel Perowne, Leslie Morrison Gutman

“…ResultsThematic analysis revealed a total of 20 inductive themes within 10 TDF domains—9 (45%) for engagement and 11 (55%) for moderation. …”
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Barriers and enablers to young people accessing sexual and reproductive health services in Pacific Island Countries and Territories: A scoping review. by Maggie Ikinue Baigry, Robin Ray, Daniel Lindsay, Angela Kelly-Hanku, Michelle Redman-MacLaren

“…Text data from published articles were charted inductively using thematic analysis with no predetermined codes and themes.…”
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Methylation and Expression of Retinoblastoma and Transforming Growth Factor-β1 Genes in Epstein-Barr Virus-Associated and -Negative Gastric Carcinomas by Xia Liu, Xiuming Tang, Shaoyan Zhang, Yun Wang, Xiaofeng Wang, Chengquan Zhao, Bing Luo

“…EBV has no significant effect on induction of TGF-β1 expression. Detection of RB methylation, RB expression, and TGF-β1 expression may be helpful to judge the status of tumor invasion and lymph node metastasis in gastric carcinomas.…”
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Investigation of the Effect of Astaxanthin on Autophagy in Renal Ischemia-reperfusion Modeled Rats by Aysegul KISAOGLU, Evren KOSE, Nesibe YILMAZ, Kevser TANBEK, Azibe YILDIZ, Umit YILMAZ, Rumeyza Hilal CIRIK, Davut OZBAG

“…Furthermore, high-dose ATX administration protected kidney tissue via autophagy induction in this study.…”
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Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence. by Rodrigo Papa-Gobbi, Pablo Stringa, Maria Virginia Gentilini, Ivana Ivanoff, Mariana Machuca, Nidia Monserrat Arreola, Javier Serradilla, Karla Estefanía-Fernández, Paloma Talayero, María Velayos, Elena Sánchez-Zapardiel, Gabriel Gondolesi, Ane Andrés-Moreno, Martin Rumbo, Francisco Hernández-Oliveros

“…Regulatory T-cells (Tregs) are key players in the induction and maintenance of peripheral tolerance, suggesting their potential involvement in modulating host vs. graft responses after ITx. …”
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siRNA-mediated inhibition of hTERT enhances the effects of curcumin in promoting cell death in precursor-B acute lymphoblastic leukemia cells: an in silico and in vitro study by Muhammad Hossein Ashoub, Ali Afgar, Alireza Farsinejad, Razieh Razavi, Samira Anvari, Ahmad Fatemi

“…The cell-type-specific responses suggest promising therapeutic strategies through combined hTERT suppression and ferroptosis induction.…”
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Determination of the Levels of Heavy Metals and Formaldehyde in Baby Clothes in South Africa: A Case Study of Stores in the Greater Cape Town Region by P. Nyamukamba, C. Bantom, Z. Mququ, T. Ngcobo, S. Isaacs

“…The concentrations of the heavy metals were determined by inductively coupled plasma (ICP) after wet digestion and also after extraction using artificial sweat for a selected range of skin-contact baby apparel. …”
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Using Micro-Learning to Enhance Knowledge and Skills of Airway Management in Nurse Anesthesia Students: An Interventional Study by Masoumeh Albooghobeish, Alireza Ghalandeh, Ali Khalafi, Mohammad Hosein Haghighizadeh

“…The intervention focused on airway management during peri-induction of general anesthesia. Then, the first and second Post-tests were given to assess the acquisition and retention of knowledge and skills, using a researcher-made instrument called AMAI-NA. …”
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Nurses’ experiences of text-based digital triage at primary healthcare centres in Sweden: a qualitative interview study by Ester Rydell, Ulf Jakobsson, Sigrid Stjernswärd

“…Methods A qualitative inductive design was chosen for the current study. …”
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Stage-specific function of sphingolipid synthases in African trypanosomes by Norton Heise, Carolina M. Koeller, Mohamed Sharif, James D. Bangs

“…The relative stage-specific expression of each TbSLS paralog was compared, and the results match phosphosphingolipid content. Induction of pan-specific RNAi silencing was lethal in both BSF and PCF. …”
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Guar gum-modified magnetic palladium nanocatalyst: C–N coupling reaction and STAT3-Mediated breast cancer therapy by Junrui Luan, Xin Dong, Shuwen Zhou

“…The presence of the material resulted in a 40–50% induction of cell apoptosis, along with down regulation of the anti-apoptotic marker. …”
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Assessment of aluminium level in commercial pasteurized and UHT milk in Bangladesh and their potential health risks by Ishrat Jahan, Kazi Md. Al-Noman, Shabbir Ahmed, Mst. Umme Habiba, S. A. Masudul Hoque, Abu Sadeque Md. Selim, Md. Morshedur Rahman

“…This study aimed to measure Al concentrations in these processed products using inductively coupled plasma mass spectrometry (ICP-MS) and assess the associated health risks. …”
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Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by O. A. Koval, O. Y. Volkova, A. A. Gorchakov, S. V. Kulemzin, A. V. Tkachenko, A. A. Nushtaeva, E. V. Kuligina, V. A. Richter, A. V. Taranin

“…Despite the multitude of anticancer cytostatic drugs available to oncologists today, most of such drugs have serious side effects that may preclude their use in some groups of patients. Hence, selective induction of apoptosis in cancer but not normal cells remains an attractive goal of molecular medicine. …”
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FOOD SECURITY IN SOUTH ASIA: MAJOR CHALLENGES AND SOLUTIONS by N. V. Galistcheva

“…The methodological basis of the study is such methods as induction and deduction, analysis and synthesis. The systematic approach to the overall study of the South Asian countries’ economy and the state of its food security in particular has become the base of this research. …”
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