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2341
Use of Minimal Residual Disease Status to Reduce Uncertainty in Estimating Long-term Survival Outcomes for Newly Diagnosed Multiple Myeloma Patients
Published 2023-01-01“…**Methods:** Standard and response-based PSMs, estimating patient life-years (LYs) over a lifetime horizon, were developed for NDMM patients treated with bortezomib, thalidomide, and dexamethasone (BTd) with or without daratumumab as induction and consolidation therapy. In the standard PSM, LYs were determined by extrapolations from individual patient data from CASSIOPEIA. …”
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2342
Genes underlying cold acclimation in the tea plant (<i>Camellia sinensis</i> (L.) Kuntze)
Published 2020-01-01“…The accumulation of CBF transcripts occurs after 15 min of chilling induction, and longer cold stress leads to accumulation of CBF transcripts. …”
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2343
Thrombin Induces COX-2 and PGE2 Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells
Published 2022-01-01“…The inflammation of the airway and lung could be triggered by upregulation cyclooxygenase (COX)-2 and prostaglandin E2 (PGE2) induced by various proinflammatory factors. COX-2 induction by thrombin has been shown to play a vital role in various inflammatory diseases. …”
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2344
Narratives of change: how climate change narratives have evolved since the 1970s
Published 2024-12-01“…Semistructured interviews were conducted with a sample of 12 experts in the field using narrative analysis. We adopted an inductive approach, allowing climate narratives to emerge organically from the interview data, and facilitating the emergence of new topics and perspectives. …”
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2345
Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice
Published 2018-01-01“…Notably, the treatment of lobeglitazone increased the protein levels of PPARα and diminished levels of PPARγ phosphorylated at serine 273, which were increased by a HFD, suggesting that induction of PPARα and posttranslational modification of PPARγ in livers by lobeglitazone might be an underlying mechanism of the improvement seen in NAFLD. …”
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2346
Identifying the Geographical Origin of Tobacco Leaf by Strontium and Lead Isotopic with Mineral Elemental Fingerprint
Published 2022-01-01“…And nine mineral element contents and four strontium and lead isotope ratios of the tobacco leaves were determined by thermal ionization mass spectrometry (TIMS) and inductively coupled plasma mass spectrometry (ICP-MS). …”
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2347
ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro
Published 2016-01-01“…Meanwhile, the decrease of ZO-1 and occludin was significantly attenuated by P2X7R inhibitors, as well as IL-1R and MMP antagonists. Further, the induction of IL-1β and MMP-9 was closely linked to ATP/P2X7R-associated BBB leakage. …”
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2348
(−)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells
Published 2025-01-01“…The combination of EGCG or quercetin, both of which change the cellular distribution of QSOX1, with sorafenib, which has no influence on the cellular distribution of QSOX1, exhibited multiple synergistic effects against the HCC cells, including the induction of apoptosis and inhibition of invasion and metastasis. …”
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2349
Cancer-associated fibroblasts and their role in tumor progression
Published 2022-03-01“…These changes lead to sequential molecular alterations, including the induction of specified transcriptional factors that result in the CAFs activation. …”
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2350
Microspore embryogenesis in vitro: the role of stresses
Published 2019-02-01“…We summarize data concerning the role of various stresses in the induction of microspore embryogenesis and possible mechanisms of their action at cellular and molecular levels. …”
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2351
The impact of welfare technology on care ethics: a qualitative analysis of healthcare professionals and managers’ experiences with welfare technologies
Published 2025-01-01“…Interviews with suppliers/manufacturers of welfare technology (GPS, pill dispensers and robotics) were also conducted. We combined an inductive approach with theoretical exploration as we alternated between the empirical data, a thematic approach, and theories of technology and care ethics. …”
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2352
Carbon monoxide-oxidising Pseudomonadota on volcanic deposits
Published 2025-01-01“…Each strain oxidised CO specifically at stationary phase but the conditions for induction of CODH expression were distinct. Cupriavidus strain CV2 expressed CODH only when CO was added to cultures (100 ppm), while Pb. terrae COX expressed CODH regardless of supplementary CO addition. …”
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2353
Early and Midterm Outcome of Surgical Repair of Total Anomalous Pulmonary Venous Connection
Published 2024-07-01“…Mortality occurred in 9 (33.33%) patients due to cardiac arrest during anesthesia induction in 1 (3.7%) patient, sepsis in 2 (7.41%) patients, LCOP in 4 (14.81%) patients and pulmonary hypertensive crisis in 2 (7.41%) patients. …”
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2354
High Serum Alkaline Phosphatase Flare after First-Line Androgen Deprivation Therapy Predicts Poor Prognosis in Metastatic Prostate Cancer Patients Treated with Second-Generation An...
Published 2021-01-01“…Chemotherapy for patients with a higher ALP flare ratio 1 month after induction of ADT may be a clinically relevant decision.…”
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2355
Electroacupuncture Treatment Alleviates the Remifentanil-Induced Hyperalgesia by Regulating the Activities of the Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats
Published 2018-01-01“…RF was administered to rats via the tail vein for OIH induction. Paw withdrawal threshold (PWT) in response to mechanical stimuli and paw withdrawal latency (PWL) to thermal stimulation were tested in rats for the assessment of mechanical allodynia and thermal hyperalgesia, respectively. …”
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2356
Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases
Published 2019-01-01“…IL-17A plays a central role in the cartilage damage through the induction of collagenases and by decreasing the expression of their inhibitors in synergy with the other proinflammatory cytokines. …”
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2357
Clarification and development of advanced practice roles in a Swiss French university hospital: an action research study
Published 2025-01-01“…Survey data were analyzed with descriptive statistics, and an inductive content analysis method was used for semi-structured interviews and the group interview. …”
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2358
Explaining the technological cooperation of knowledge and business ecosystems: an approach based on ecotone and ambidextrous organization theories
Published 2024-06-01“…Therefore, the paper aims to develop a conceptual model to explain the cooperation between knowledge and business ecosystems.Methodology: This research is interpretive from a philosophical point of view and inductive from the point of view of theory development. …”
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2359
Social inclusion programming for older adults living in age-friendly cities: a scoping review
Published 2025-01-01“…This scoping review explores innovative programmes implemented by AFCs to enhance social inclusion for older adults.Design A scoping review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines.Data sources Systematic searches were conducted between December 2023 and January 2024 across relevant databases (Ovid Medline, OVID Embase, OVID PsycINFO, CINAHL, Web of Science, Cochrane Library and Scopus) and the grey literature.Eligibility criteria for selecting studies Selection criteria included English language publications describing evaluated age-friendly, social inclusion programmes for older adults.Data extraction and synthesis Data extraction followed Gonyea and Hudson’s (2015) framework assessing programmes on population, environment and/or sector inclusion levels. Inductive analysis identified and evaluated aspects of social inclusion.Results We identified 20 peer-reviewed publications and 18 grey literature sources. …”
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2360
TransformerPayne: Enhancing Spectral Emulation Accuracy and Data Efficiency by Capturing Long-range Correlations
Published 2025-01-01“…While scaling up The Payne to a larger network reduced its MAE from 1.2% to 0.3% when trained on the full data set, TransformerPayne consistently achieved the lowest MAE across all tests. The inductive biases of the TransformerPayne emulator enhance accuracy, data efficiency, and interpretability for spectral emulation compared to existing methods.…”
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