Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

“…Conclusions Overall, our data suggest that ER stress induction in pDCs promotes fibroblast activation, which may contribute to the development of fibrosis in SSc.…”
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Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries by Peter William Kemewele Saague, Bruno Moukette Moukette, Jacques Romain Njimou, Prosper Cabral Nya Biapa, Francine Nzufo Tankeu, Vicky Joseline Ama Moor, Constant Anatole Pieme, Jeanne Yonkeu Ngogang

“…The extract of T. tetraptera was administered at doses of 50 mg/kg and 100 mg/kg for 07 per os to rats before the induction of hepatotoxicity with of 2 ml/kg of 1:1 (v/v) carbon tetrachloride (CCl4) and olive oil through intraperitoneal route. …”
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Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells by Jiangyi Wang, Guoqing Li, Lei Hu, Fei Yan, Bin Zhao, Xiaoshan Wu, Chunmei Zhang, Jinsong Wang, Juan Du, Songlin Wang

“…Human DPSCs were isolated and cultured in osteogenic induction medium with or without RA or BMS 493, an inverse agonist of the pan-retinoic acid receptors (pan-RARs). …”
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EFFORTS IN CONTROLLING COAL DUST HAZARDS IN THE STOCKPILE AREA OF A STEAM POWER PLANT (PLTU) by Alifiah Rizky Rosydah, Y. Denny Ardyanto Wahyudiono, Ahmad Imaduddin, Dani Nasirul Haqi, Meirina Ernawati

“…POMI included the installation of a spray gun, a dust suppression system, reforestation, and ventilation setting. Further, OHS induction was conducted, together with safety talk, working hour regulations, toolbox meeting, training on the use of PPE, Medical Check Up (MCU), person authorization, preventive maintenance, and the use of PPE by workers. …”
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Youth Understanding of Healthy Eating and Obesity: A Focus Group Study by Allison C. Sylvetsky, Monique Hennink, Dawn Comeau, Jean A. Welsh, Trisha Hardy, Linda Matzigkeit, Deanne W. Swan, Stephanie M. Walsh, Miriam B. Vos

“…We conducted a secondary analysis of the qualitative FGD transcripts using inductive thematic coding to identify key themes related to youth reports of family eating habits (including food preparation, meal frequency, and eating environment), perceived facilitators and barriers of healthy diet, and knowledge about obesity and its complications. …”
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Aspergillus fumigatus is responsible for inflammation in a murine model of chronic obstructive pulmonary disease exacerbation by Alexandra Bouyssi, Alexis Trecourt, Tanguy Déméautis, Florence Persat, Olivier Glehen, Martine Wallon, Gilles Devouassoux, Abderrazzak Bentaher, Jean Menotti

“…Results In co-cultures of macrophages and epithelial cells treated with both cigarette smoke extracts (CSE) and A. fumigatus compared to CSE alone there were significant inductions in TNF-α (6.2-fold) and CXCL-2 (21.5-fold) gene expression, confirmed by significant increases in the corresponding protein secretion. …”
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A pilot mixed methods randomized control trial investigating the feasibility and acceptability of a culturally tailored intervention focused on beliefs, mistrust and race-congruent... by Meng-Jung Wen, Martha Maurer, Annika L. Pickard, Makenzie Hansen, Olayinka O. Shiyanbola

“…Qualitative content analysis inductively explored participants’ feedback on the program, participation barriers and potential strategies to overcome the challenges. …”
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Implementation of patient-centred care: which organisational determinants matter from decision maker’s perspective? Results from a qualitative interview study across various health... by Lena Ansmann, Holger Pfaff, Kira Isabel Hower, Vera Vennedey, Hendrik Ansgar Hillen, Ludwig Kuntz, Stephanie Stock

“…Our qualitative study examines determinants of PCC implementation from decision makers’ perspectives across diverse HSCOs.Design Qualitative study of n=24 participants in n=20 semistructured face-to-face interviews conducted from August 2017 to May 2018.Setting and participants Decision makers were recruited from multiple HSCOs in the region of the city of Cologne, Germany, based on a maximum variation sampling strategy varying by HSCOs types.Outcomes The qualitative interviews were analysed using an inductive and deductive approach according to qualitative content analysis. …”
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Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms by Vladan P. Čokić, Olivera Mitrović-Ajtić, Bojana B. Beleslin-Čokić, Dragana Marković, Marijana Buač, Miloš Diklić, Nada Kraguljac-Kurtović, Svetozar Damjanović, Pavle Milenković, Mirjana Gotić, Puri K. Raj

“…Therefore, the JAK2V617F mutant allele burden participated in inflammation biomarkers induction and related signaling pathways activation in MPNs.…”
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A qualitative mystery shopper study that de(codes) the experiences of English and Spanish-speaking patients who call to schedule a first-time primary care appointment in the Los An... by Esmeralda Melgoza, Ahmad Ismail, Lucía Félix-Beltrán, Rosario Majano, Arturo Vargas Bustamante

“…The researchers then inductively coded the transcripts using thematic analysis on Dedoose version 9.2.012. …”
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Comparison of intraoperative neurophysiological monitoring between propofol and remimazolam during total intravenous anesthesia in the cervical spine surgery: a prospective, double... by Myoung Hwa Kim, Jinyoung Park, Yoon Ghil Park, Yong Eun Cho, Dawoon Kim, Dong Jun Lee, Kyu Wan Kwak, Jongyun Lee, Dong Woo Han

“…SEP latencies and amplitudes and motor-evoked potential (MEP) amplitudes were measured 30 min after anesthetic induction (T1), 30 min after surgical incision (T2), after laminectomy or discectomy (T3), immediately after plate insertion or pedicle screw fixation (T4), and before surgical wound closure (T5). …”
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Equivalent method for DFIG wind farms based on modified LightGBM considering voltage deep drop faults by Xuecheng Liu, Peixiao Fan, Jun Yang, Song Ke, Binyu Ma, Yangzhou Pei, Jian Xu

“…To address the challenges of inadequate accuracy in identifying the Crowbar action state and incomplete consideration of operating scenarios in existing methods for Doubly Fed Induction Generator (DFIG) wind farms, a DFIG wind farm equivalent method based on modified Light Gradient Boosting Machine (mLightGBM) considering voltage deep drop faults is proposed. …”
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Significant Cytokine mRNA Expression Changes Immediately after Initiation of Cardiopulmonary Resuscitation by Mareen Braunstein, Martina Williamson, Thomas Kusmenkov, Jürgen Landes, Peter Biberthaler, Karl-Georg Kanz, Wolfgang Böcker, Viktoria Bogner

“…TNF-alpha, IL-8, IL-10, and IL-1ra mRNA levels were quantified by RT-qPCR and compared to multiple organ failure, 30-day survival, and the induction of therapeutic hypothermia (TH). Results. 25 patients (63 ± 15 years) were enrolled presenting a characteristic time-dependent cytokine profile in the early postresuscitation period. …”
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The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways by Ju Ang Kim, Soomin Im, Jiwon Lim, Jung Min Hong, Hye Jung Ihn, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Eui Kyun Park

“…Calvarial defect and ectopic bone formation models demonstrated significant induction of bone regeneration in Dock5 KO mice compared to wild-type (WT) mice. …”
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Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist P... by Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw

“…Members of this peptide group are also common components of reptile and arthropod venoms due to their multiple biological functions that include induction of pain, effects on many smooth muscle types, and lowering systemic blood pressure. …”
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Exploratory analysis of potential toxic elements in Moroccan couscous and health risk evaluation utilizing ICP-OES by Othmane Hammani, Najlae El-Otmani, Omar Ben Lenda, Hamza El Azhari, Abderrazak Rfaki, Naima Lahlouhi, Youssef Mourad, Abdelaziz Abdallaoui

“…Methods: The samples were subjected to analysis using an Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES) following the complete mineralisation of the samples. …”
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Chlorophyll performances as an indicator of compost quality: Effectiveness of liquid humic substances and compost tea by Bouchra El Hayany, Khaoula En-Nejmy, Ghizlen El Mezouari El Glaoui, Mohamed Hafidi, Loubna El Fels

“…Purpose: This study was carried out with the aim of improving the use of compost products as compost tea and humic substances fertilizers, to study the evolution and the degree of compost maturity, and to use the chlorophyll as an indicator of compost quality.Method: The compost tea and humic substances were prepared from different stages of a windrow compost (1/2 dewatered lagooning sludge + 1/2 green waste), the mineral content was investigated using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) analysis. …”
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Interplay between Intravitreal RvD1 and Local Endogenous Sirtuin-1 in the Protection from Endotoxin-Induced Uveitis in Rats by S. Rossi, C. Di Filippo, C. Gesualdo, F. Testa, M. C. Trotta, R. Maisto, B. Ferraro, F. Ferraraccio, M. Accardo, F. Simonelli, M. D’Amico

“….), a specific inhibitor of SIRT1 activity, for 7 days prior to the induction of EIU in rats. Similarly, the effects of RvD1 (1000 ng/kg) on the SIRT1 protein expression were abolished by Boc2, N-t-butoxycarbonyl-PLPLP, a specific formyl-peptide receptor type 2/lipoxin A receptor antagonist. …”
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Recent Developments in Heavy Metals Detection: Modified Electrodes, Pretreatment Methods, Prediction Models and Algorithms by Yujie Shi, Shijie Zhang, Hang Zhou, Yue Dong, Gang Liu, Wenshuai Ye, Renjie He, Guo Zhao

“…This review aims to highlight the commonly used methods for detecting heavy metals (such as atomic absorption spectroscopy (AAS), atomic emission spectroscopy (AES), inductively coupled plasma–mass spectrometry (ICP-MS), square-wave anodic stripping voltammetry (SWASV), etc.), with a particular focus on electrochemical detection and electrode modification materials. …”
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Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia by Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida

“…VPA treatment upregulated the expression of Bax and Bak, further supporting apoptosis induction. The cell death induced by the venetoclax–VPA combination was predominantly apoptotic, as confirmed by the near-complete blockade of cell death by a pan-caspase inhibitor. …”
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