TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma by Hanrui Guo, Meiling Wang, Caiya Ni, Chun Yang, Chunxue Fu, Xiaoman Zhang, Xueling Chen, Xiangwei Wu, Jun Hou, Lianghai Wang

“…TGF-β1 was found to be positively correlated with TREM2 expression in HCC, and TGF-β blockade reversed TREM2 induction. On the other hand, TREM2+ macrophages were found to be associated with glycolysis and PKM2 expression in HCC cells; this association may be related to the secretion of IL-1β, which enhances the malignant phenotypes of HCC cells. …”
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Infection and HLA-G Molecules in Nasal Polyposis by Roberta Rizzo, Nicola Malagutti, Daria Bortolotti, Valentina Gentili, Antonella Rotola, Enrico Fainardi, Teresa Pezzolo, Claudia Aimoni, Stefano Pelucchi, Dario Di Luca, Antonio Pastore

“…Human papillomavirus (HPV) infection is one candidate for the development of SNP for its epithelial cell trophism, hyperproliferative effect, and the induction of immune-modulatory molecules as HLA-G. …”
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Co-occurrence of a Mullerian anomaly and Kallmann syndrome: A case report by Lea C. George, Rebecca Gendelman, Anat Chemerinski, Pierre Lespinasse, Inessa A. Goldman, Sara Morelli

“…Kallmann syndrome has rarely been reported with Mullerian anomalies; in this case it represents a scenario in which the induction of puberty and menses brought an obstructive anomaly to light. …”
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Optimized Resonators for Piezoelectric Power Conversion by Weston D. Braun, Eric A. Stolt, Lei Gu, Jeronimo Jeronimo Segovia-Fernandez, Sombuddha Chakraborty, Ruochen Lu, Juan M. Rivas-Davila

“…Piezoelectric resonators can have a very high quality factor and provide an inductive impedance between their series and parallel resonant frequencies, making them a promising technology for further miniaturizing dc-dc converters. …”
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Prophylactic Subacute Administration of Zinc Increases CCL2, CCR2, FGF2, and IGF-1 Expression and Prevents the Long-Term Memory Loss in a Rat Model of Cerebral Hypoxia-Ischemia by Victor Manuel Blanco-Alvarez, Guadalupe Soto-Rodriguez, Juan Antonio Gonzalez-Barrios, Daniel Martinez-Fong, Eduardo Brambila, Maricela Torres-Soto, Ana Karina Aguilar-Peralta, Alejandro Gonzalez-Vazquez, Constantino Tomás-Sanchez, I. Daniel Limón, Jose R. Eguibar, Araceli Ugarte, Jeanett Hernandez-Castillo, Bertha Alicia Leon-Chavez

“…These results might be explained by the induction of neural plasticity because of the expression of CCL2 and growth factors.…”
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Anaesthetic Management of a Neonate with Ebstein’s Anomaly Undergoing a Meningomyelocele Surgery: A Case Report by Prakriti, Monika Yadav, Vaishali Gupta, Komal Yadav, Shikha Garg

“…General anaesthesia with inhalational induction was planned. Perioperative considerations for this patient included right-to-left shunting with the possibility of paradoxical emboli, prolonged onset time for intravenous drugs due to pooling and recirculation of blood in the right atrium, increased Pulmonary Vascular Resistance (PVR), perioperative pulmonary hypertension, right and left ventricular dysfunction, and arrhythmias. …”
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Evaluation of Stability of Surface-Treated Mini-Implants in Diabetic Rabbits by Nam-Hee Oh, Eun-Young Kim, Janghyun Paek, Yoon-Ah Kook, Do-Min Jeong, Il-Sik Cho, Gerald Nelson

“…A total of 48 mini-implants were placed after four weeks of diabetic induction. 24 mini-implants were surface-treated with SLA (sandblasted with large grit, and acid etched) and the remaining 24 mini-implants had smooth surfaces. …”
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Grid-Integrated Dual Wind Turbine System Using SEPIC Converter with Whale Optimized PI Controller by Kishore R.D., Sravani K., Sai Kumar N.D., Preetham C.G., Bentu B.2

“…Main objectives of the study are to progress a dual independent doubly fed induction generator (DFIG)-based wind energy conversion system (WECS) for stable and efficient power delivery to an AC microgrid while ensuring grid stability and compliance with power quality standards. …”
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Bread wheat callusogenesis and organogenesis using mature embryos as explants by G. R. Gumerova, A. A. Galimova, B. R. Kuluev

“…With this in view, the regeneration potential of two spring (‘Saratovskaya 55’ and ‘Sigma’) and three winter (‘Tanya’, ‘Fisht’ and ‘Pamyat’) cultivars of bread wheat was assessed, and optimal conditions were identified for callus induction and organogenesis using mature embryos.   …”
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Feasibility of implementing a rapid-learning methodology to inform radiotherapy treatments: key professional stakeholders’ views by Corinne Faivre-Finn, Kevin Franks, Fiona McDonald, David P French, Daniel Johnson, Arbaz Kapadi, Gareth Price, Rebecca Holley, Kate Wicks, Kathryn Banfill, Gareth Webster

“…Data were collected between December 2022 and May 2023, and analysed using inductive thematic analysis.Results Four themes were generated: (1) the alignment of rapid-learning methodologies with the reality of practice, (2) concerns related to the variability of RWD, (3) the maturity of data infrastructures and capacity for rapid-learning and (4) further support, education and evidence needed to convince stakeholders to adopt rapid-learning approaches.Conclusion The potential of rapid-learning to help address evidence gaps in radiotherapy development was positively received by different professional stakeholders. …”
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How do doctors manage physical activity advocacy for patients and their own self-care? A qualitative interview study of general practitioners in Ireland by Andrew O'Regan, Vikram Niranjan, Amanda Clifford, Joe MacDonagh, Ibak Baky, Alison Bourke, Conor Byrne

“…Data was analysed by an interdisciplinary team of researchers using an inductive thematic approach.Setting and participants Participants were GPs (n=21) and were recruited from an education and research network.Findings A single meta-theme was identified—moving towards more physically active lifestyles through the art of medicine—with three related subthemes. …”
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Temperature influence on the repair of a hardfacing coating using laser metal deposition and assessment of the repair innocuity by Wilfried Pacquentin, Pierre Wident, Jérôme Varlet, Thomas Cailloux, Hicham Maskrot

“…We describe our process which successfully prevents crack formation both during and after the repair, highlighting the design of the preliminary part machining phase, induction heating of an extended part volume during the laser repair phase and the optimal scanning strategy. …”
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The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation by Malihe Moradzadeh, Sirous Tayebi, Hossein Poustchi, Kourosh Sayehmiri, Parisa Shahnazari, Elnaz Naderi, Ghodratollah Montazeri, Ashraf Mohamadkhani

“…Moreover TLR2 is critical for induction of inflammatory cytokines and therefore ALT elevation.…”
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Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy by Shunqiao Jin, Shunqiao Jin, Xiaojiao Liu, Xiaojiao Liu, Lingqin Cai, Lingqin Cai, Jiayu Yan, Ling Li, Hongjun Dong, Yuxue Gao, Xicong Zhu, Cong Zhang, Xuezhu Xu

“…This study investigates the inductive effect of itraconazole on autophagy-mediated apoptosis in melanoma cells.MethodPotential drug targets were identified using the PMF machine learning algorithm. …”
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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

“…Pathogenicity assays demonstrated that the virulence of the offspring strains triggered by continuous induction of disease-resistant cotton cultivar increased from the 4th generation and reached its peak by the 6th generation. …”
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Interleukin-12p70 Expression by Dendritic Cells of HIV-1-Infected Patients Fails to Stimulate gag-Specific Immune Responses by Ellen Van Gulck, Nathalie Cools, Derek Atkinson, Lotte Bracke, Katleen Vereecken, Marc Vekemans, Viggo F. I. Van Tendeloo, Zwi N. Berneman, Guido Vanham

“…Since dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique capability to stimulate naïve T cells into effector T cells, their use for the induction of HIV-specific immune responses has been studied intensively. …”
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Effects of Acute Normovolemic Anemia on Hemodynamic Parameters and Acid-Base Balance in Dogs by Tatiana Champion, Glaucia Bueno Pereira Neto, Aparecido Antonio Camacho

“…The dogs (n=10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18%) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2 : 1 ratio. …”
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Benzothiazole (BTH) Induced Resistance of Navel Orange Fruit and Maintained Fruit Quality during Storage by Huaying Du, Ying Sun, Rui Yang, Wei Zhang, Chunpeng Wan, Jinyin Chen, İbrahim Kahramanoğlu, Liqin Zhu

“…Recently, a synthetically prepared novel BTH was introduced that elicits the induction of resistance against various diseases of fruits. …”
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Rotavirus VP6 Adjuvant Effect on Norovirus GII.4 Virus-Like Particle Uptake and Presentation by Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo by Kirsi Tamminen, Suvi Heinimäki, Timo Vesikari, Vesna Blazevic

“…The adjuvant effect of VP6 on GII.4 VLP presentation and NoV-specific immune response induction by BMDC in vivo was also studied. Intracellular staining demonstrated that BMDCs internalized both antigens, but VP6 more efficiently than NoV VLPs. …”
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Characterization of Bozitinib as a potential therapeutic agent for MET-amplified gastric cancer by Hang Lin, Lingzhi Qu, Hudie Wei, Ming Guo, Xiaojuan Chen, Qianmeng Lin, Huajun Zhang, Shuyan Dai, Yongheng Chen

“…Bozitinib demonstrates a strong effect on MET-amplified gastric cancer cells by blocking the c-Met signaling pathway, leading to the inhibition of cell proliferation and survival, as well as the induction of G0/G1 phase arrest and apoptosis. Structurally, bozitinib is optimally embedded in the ATP pocket of c-Met and firmly binds via an extensive interaction network. …”
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