Analysis of panel physician inquiries to U.S. TB Centers of Excellence, 2018–2022 by E. Leithead IV, S. Subramanian, K. Pimenta, N.D. Goswami, A. Patrawalla, A. Lardizabal, C. Haley, L. Chen, L. Armitige, B. Seaworth, B. Sylvester, R. Bhavaraju

“…METHODS: TB-related queries in the COE MCD from January 1, 2018, to December 31, 2022, were analyzed using a descriptive coding scheme developed through inductive analysis, allowing multiple themes per entry. …”
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Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer by Gholamreza Asadikaram, Mohammad Reza Ashrafi, Sodaif Darvish Moghaddam, Moslem Abolhassani, Fatemeh Bagheri

“…Our results showed that progression from functional dyspepsia towards intestinal metaplasia and gastric cancer was associated with elevations in organochlorine pesticide serum levels, which had an association with the induction of oxidative stress and the reduction of antioxidant and acetylcholine esterase enzyme activities.…”
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Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition by Aimin Yang, Xia Xiao, Mingfeng Zhao, Amanda C. LaRue, Bradley A. Schulte, Gavin Y. Wang

“…Here we report that dual inhibition of mTORC1/2 by AZD or its analogue (KU-63794) depletes mouse BM Lin−Sca-1+c-Kit+ cells in cultures via the induction of apoptotic cell death. Subsequent colony-forming unit (CFU) assays revealed that inhibition of mTORC1/2 suppresses the clonogenic function of hematopoietic progenitor cells (HPCs) in a dose-dependent manner. …”
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Escin Chemosensitizes Human Pancreatic Cancer Cells and Inhibits the Nuclear Factor-kappaB Signaling Pathway by A. Rimmon, A. Vexler, L. Berkovich, G. Earon, I. Ron, S. Lev-Ari

“…Synergistic effect of combined therapy was determined by CalcuSyn software. Cell cycle and induction of apoptosis were evaluated by FACS analysis. …”
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Key components in the professional ethics of sign language interpreters in healthcare contexts: a qualitative study in Colombia by Nora Ellen Groce, Samia Hurst, Laura Catalina Izquierdo Martínez, Angela Martínez-R, Jessica Cuculick, Minerva C Rivas Velarde

“…Objectives To identified the core components of professional ethics for medical sign language interpreters and develop a framework based on empirical data from Colombian sign language (CSL) interpreters.Design Purposive and snowball sampling methods were used in this qualitative study, which involved conducting semistructured interviews to CSL interpreters. Inductive data analysis was performed using the constant comparative method, where data collection and analysis occurred simultaneously. …”
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Matrix Metalloproteinase-9 Production following Cardiopulmonary Bypass Was Not Associated with Pulmonary Dysfunction after Cardiac Surgery by Tso-Chou Lin, Feng-Yen Lin, Yi-Wen Lin, Che-Hao Hsu, Go-Shine Huang, Zhi-Fu Wu, Yi-Ting Tsai, Chih-Yuan Lin, Chi-Yuan Li, Chien-Sung Tsai

“…Arterial blood was sampled at 6 sequential points (before anesthesia induction, before CPB and at 2, 4, 6, and 24 h after beginning CPB) for plasma MMP-9 concentrations by ELISA. …”
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Simultaneous exposure to microplastics and heavy metal lead induces oxidative stress, histopathological damage, and immune dysfunction in marine mussel Mytilus coruscus by Chuanyue Chen, Xueer Wang, Yingrong Jin, Yinchang Yao, Suchang Li, Zhi Liao, Xiaolin Zhang, Xiaojun Yan

“…Meanwhile, co-exposure poses a significant threat to the immune function of the mussels, as evidenced by induction of hemocytes to produce excess reactive oxygen species (ROS), significantly reducing lysosome activity (p < 0.05), inhibiting the expression of autophagy-related genes, and inducing the expression of apoptosis-related genes, resulting in hemocyte apoptosis. …”
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Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice by Tomoko Kawakami, Nitin Puri, Komal Sodhi, Lars Bellner, Toru Takahashi, Kiyoshi Morita, Rita Rezzani, Tim D. Oury, Nader G. Abraham

“…Heme oxygenase (HO) system is one of the key regulators of cellular redox homeostasis which responds to oxidative stress (ROS) via HO-1 induction. However, recent reports have suggested an inhibitory effect of ROS on HO activity. …”
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What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells? by R. N. Bárcia, J. M. Santos, M. Filipe, M. Teixeira, J. P. Martins, J. Almeida, A. Água-Doce, S. C. P. Almeida, A. Varela, S. Pohl, K. E. J. Dittmar, S. Calado, S. I. Simões, M. M. Gaspar, M. E. M. Cruz, W. Lindenmaier, L. Graça, H. Cruz, P. E. Cruz

“…Immunogenicity and immunosuppression were assessed by mixed lymphocyte reactions, suppression of lymphocyte proliferation and induction of regulatory T cells. Results showed that UCX were less immunogenic and showed higher immunosuppression activity than BM-MSCs. …”
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Comparison of the Effectiveness of Warmed Versus Room Temperature Intravenous Fluids Administration to Prevent Intraoperative Heat Loss in Anaesthetised Calves Undergoing Umbilical... by Sitkican Okur, Latif Emrah Yanmaz, Mumin Gökhan Senocak, Ayse Golgeli, Ferda Turgut, Omer Tarik Orhun, Yakup Kocaman, Ugur Ersoz

“…Pulse rate (PR), respiratory rate (fR), peripheral haemoglobin oxygen saturation (SpO2) and rectal temperature (RT) were recorded immediately after the onset of anaesthesia induction (T0) at T5, T10, T15, T30, T45 and T60. Duration of anaesthesia, surgery time and recovery scores were also noted. …”
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Network Representation Based on the Joint Learning of Three Feature Views by Zhonglin Ye, Haixing Zhao, Ke Zhang, Zhaoyang Wang, Yu Zhu

“…Based on the above two optimization approaches, we propose a novel network representation learning algorithm, Network Representation learning algorithm based on the joint optimization of Three Features (TFNR). Based on Inductive Matrix Completion (IMC), TFNR algorithm introduces the future probabilities between vertices without edges and text features into the procedure of modeling network structures, which can avoid the problem of the network structure sparse. …”
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Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure by Patrick Geraghty, Nathalie Baumlin, Matthias A. Salathe, Robert F. Foronjy, Jeanine M. D’Armiento

“…Loss of Gpx-1 expression enhanced cigarette smoke-induced ER stress and apoptosis. Equally, induction of ER stress with tunicamycin enhanced antioxidant expression in mouse precision-cut lung slices. …”
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Metallurgical Processing of CoCrFeNi High-Entropy Alloy by P. Müller, A. Zadera, L. Čamek, M. Myška, V. Pernica

“…In order to achieve optimum alloy properties, it is necessary to minimise their content using various metallurgical processes The aim of the work was the metallurgical processing of CoCrFeNi alloy melted from scrap metal in an induction furnace. The desired reduction of carbon (to 100 ppm) and nitrogen content (from 660 to ~60 ppm) was reached by using carbon reaction under vacuum. …”
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The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture by Bulent Demir, Burak Onal, Sibel Ozyazgan, Esra Demir, Vedat Bakuy, Ahmet Gokhan Akkan

“…Low-dose (0.1 μM/L) and high-dose (1μM/L) pitavastatin calcium were administered as a frontline therapy in human saphenous endothelial cell culture, followed by induction of inflammation by TNF-α and determination of mRNA level alterations of ICAM-1 and NF-κB genes of endothelial cells using the qRT-PCR method. …”
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Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase by Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida

“…Because in pancreatic cancers the transition to a mesenchymal phenotype coincides with the PMN infiltrate, a contribution of the inflammatory response to the induction of EMT and—by implication—to tumor progression is possible.…”
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Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81 by Meiyue Wang, Zejie Wu, Xiaoyu Zheng, Yishu Huang, Yizhou Jin, Jiaxin Song, Wanzhen Lei, Hua Liu, Riyue Yu, Haoqing Yang, Runtao Gao

“…Methods Betaine was added for SCAPs chondrogenic induction. The chondrogenic differentiation potential was assessed using Alcian Blue staining, Sirius Red staining and the main chondrogenic markers. …”
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Role of Peroxisome Proliferator-Activated Receptor β/δ and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells by Jeffrey D. Coleman, Jerry T. Thompson, Russell W. Smith, Bogdan Prokopczyk, John P. Vanden Heuvel

“…PPARβ/δ is a ligand-activated transcription factor that regulates various cellular functions via induction of target genes directly or in concert with its associated transcriptional repressor, BCL-6. …”
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A novel virtual inductor optimization methodology of virtual synchronous generators for enhanced power decoupling by Xin Zhang, Lijiao Gong, Yanjun Zhang, Xiaolei Ma, Lianshan Han, Santao Jiang, Weiji Zhou

“…This model facilitates the analysis of power stability under different control parameters and resistance-to-inductive reactance ratios in the grid line. It enables the preliminary regulation of the system’s steady-state and dynamic characteristics. …”
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Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis by Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin

“…The iHEPs exhibit morphological features and a glycogen storage function similar to those of mature hepatocytes and demonstrate an upregulation in hepatic gene programs with increasing induction time. Following transplantation, iHEPs were observed surrounding the metacestode lesions in the liver parenchyma of E. multilocularis-infected mice. iHEPs transplantation effectively restored liver function and improved liver injury in the infected mice. …”
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Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis by Min Hu, Xinyu Meng, Tong Wang, Yifan Wang, Xiaodong Chen, Dongliang Xu, Wei He, Hongjia Zhang, Wenzheng Guo, Bo Jing, Siwei Zhang, Jianhua Xu, Beibei Sun, Xueqian Sun, Tingting Liu, Na Ni, Tongtong Zhang, Wenwen Cui, Xiaoyu Wu, Liping Xia, Feng Yao, Fang Zhang, Jing Du, Jiong Deng

“…Abstract Purpose Immune checkpoint blockades (ICBs) are promising, however they do not fit all types of tumor, such as those lack of tumor antigens. Induction of potent anti-tumor T cell immunity is critical for cancer therapy. …”
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