Design, synthesis and molecular modeling study of substituted indoline-2-ones and spiro[indole-heterocycles] with potential activity against Gram-positive bacteria by Radwan Awwad Abdoh, Aanazi Fares Kaed, Al-Agamy Mohammed, Mahrous Gamal Mohammad

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Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH): A Case of Indolent Pulmonary Nodules Diagnosed with Robotic-Assisted Navigational Bronchoscopy by Adam Purdy, Firas Ido, Deborah Stahlnecker

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Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation by Adriana V. Treuer, Pedro De-La-Torre, Margarita I. Gutiérrez

“…We report a stereoselective synthesis of a series of new (E)-2-(1H-indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles (3a–3i) obtained from 3-(cyanoacetyl)indole and heteroaryl-aldehydes under microwave-assisted Knoevenagel reaction at 300 W of potency and 100°C. …”
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Synthesis, Characterization, Antimicrobial, DNA Cleavage, and Antioxidant Studies of Some Metal Complexes Derived from Schiff Base Containing Indole and Quinoline Moieties by Mahendra Raj Karekal, Vivekanand Biradar, Mruthyunjayaswamy Bennikallu Hire Mathada

“…A new Schiff base of 5-chloro-3-phenyl-1H-indole-2-carboxyhydrazide and 3-formyl-2-hydroxy-1H-quinoline (HL), and its Cu(II), Co(II), Ni(II), Zn(II), Cd(II), and Hg(II) complexes have been synthesized and characterized in the light of microanalytical, IR, H1 NMR, UV-Vis, FAB-mass, ESR, XRD, and TGA spectral studies. …”
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The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity by Zhiwei Wang, Shaying Yang, Liangju Liu, Aiqin Mao, Hao Kan, Fan Yu, Xin Ma, Lei Feng, Tingting Zhou

“…Here, we report that gut commensal Clostridia bacteria regulate host energy balance through the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA). IPA acts as an endogenous leptin sensitiser to counteract obesity. …”
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Effect of 1-(phenyl)-N’-(4-methoxybenzylidene)-9H-pyrido[3,4-b] indole-3-carbohydrazide on in vitro poliovirus replication by Santos Patricia Regina, Formagio Anelise S. Nazari, Filho Benedito Prado Dias, Nakamura Celso Vataru, Sarragiotto Maria Helena, Ueda-Nakamura Tania

Subjects: “…1-(phenyl)-n’-(4-methoxybenzylidene)-9h-pyrido[ 3,4-b]indole-3-carbohydrazide…”
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Synthesis and Antidepressant Activity of Some New 5-(1H-Indol-3-yl)-3-(substituted aryl)-4,5-dihydroisoxazoline Derivatives by Pravin O. Patil, Sanjay B. Bari

“…The present study refers to the synthesis of new antidepressant candidates using the indole scaffold. In an attempt to identify potential lead antidepressant agents, a number of indole molecules, incorporating isoxazoline, were synthesized by microwave-assisted synthesis. …”
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Synthesis and Anticancer Activity of 1-(1H-Indol-3-yl)-2-(4-diarylmethylpiperazine-1-yl)ethane-1,2-dione Derivatives by Jun-Rong Jiang, Feng Xu, Han-Gui Wu

“…Several new 1-(4-diarylmethylpiperazine-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione derivatives were synthesized by acylation of 1-diarylmethylpiperazine with 2-(1H-indol-3-yl)-2-oxoacetyl chloride. …”
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B(HSO4)3 as an Efficient Catalyst for the Syntheses of Bis(1H -Indol-3-yl)ethanones and Bis(benzotriazol-1-yl)ethanones by Mohammad Hossein Mosslemin, Abolfazl Eshghi Movahhed

“…Efficient syntheses of bis (1H-indol-3-yl)ethanones and bis (benzotriazolyl)ethanones via reaction of phenylglyoxals with indole or 1,H-benzotriazole in the presence B(HSO4)3 in solvent-free thermal and in aqueous media conditions are discribed. …”
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An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice. by Paromita Bag, Durbadal Ojha, Hemanta Mukherjee, Umesh Chandra Halder, Supriya Mondal, Nidhi S Chandra, Suman Nandi, Ashoke Sharon, Mamta Chawla Sarkar, Sekhar Chakrabarti, Debprasad Chattopadhyay

“…Based on ethnomedicinal use we have isolated a compound 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole (HM) from the traditional herb Ophiorrhiza nicobarica Balkr, and evaluated its efficacy on isolates of HSV-2 in vitro and in vivo. …”
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Synthesis and Antimicrobial and Antioxidant Activities of Some New 5-(2-Methyl-1H-indol-3-yl)-1,3,4-oxadiazol-2-amine Derivatives by Anand R. Saundane, Vaijinath A. Verma, Vijaykumar T. Katkar

“…A series of 5-(2-methyl-1H-indol-3-yl)-1,3,4-oxadiazol-2-amine derivatives (3–5) were synthesized. …”
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Mucin-Poor Mucinous Tubular and Spindle Cell Carcinoma of the Kidney Presented with Multiple Metastases Two Years after Nephrectomy: An Atypical Behaviour of a Rare, Indolent Tumour by I. Sokolakis, C. Kalogirou, L. Frey, M. Oelschläger, M. Krebs, H. Riedmiller, H. Kübler, D. Vergho

“…Although it is considered as a relatively indolent malign entity, it can metastasise even years after successful primary surgical treatment. …”
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Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions by Akanksha Mishra, Mrinal Talukdar, Alpa Y. Dave, Eeshwaraiah Begari

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Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

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The crystal structure of tert-butyl (E)-3-(2-(benzylideneamino)phenyl)-1H-indole-1-carboxylate, C26H24N2O2 by Da Weihao, Kong Haonan, Wang Ruiyao, Lin Yi

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Growth Regulator Indole-3-Butyric Acid on Rooting Potential of <i>Actinidia deliciosa</i> Rootstock and <i>Actinidia arguta</i> Female Scion Species Stem Cuttings by Mapogo Kgetjepe Sekhukhune, Yvonne Mmatshelo Maila

“…A study was conducted to access the effectiveness of exogenous application of indole-3-butyric acid (IBA) on adventitious root formation in kiwifruit semi-hardwood stem cuttings (SCs) from <i>Actinidia deliciosa</i> rootstock and <i>Actinidia arguta</i> female scion. …”
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Crystal structure of 2,2-dichloro-1-(4-chloro-1H-indol-1-yl)ethan-1-one, C10H6Cl3NO by Ma Zhao-Yu, Lu Wan, Guo Yu-Chao, Li Ying-Jiao

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Auxin signaling related to H+-ATPase synthesis and antioxidant enzyme activities regulates fluoranthene uptake by ryegrass roots by Yuanzhou Xu, Yunyun Li, Xinyue Zhang, Zhuoliang Xiao, Jiaguo Jiao, Huijuan Zhang, Huixin Li, Feng Hu, Li Xu

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Dosis de Fitomas®-E para el enraizamiento de esquejes de guayaba var. Enana Roja Cubana by Leudiyanes Ramos-Hernández, Noel J. Arozarena-Daza, José Leiscalle-Acosta, Ernesto Castañeda-Hidalgo, Gerardo Rodríguez-Ortiz, Salvador Lozano-Trejo

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Cardioprotective Activity of N′′,N′′′-Bis[5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]carbonohydrazide Derivative against Doxorubicin Induced Cardiotoxicity in Rats by Salma Tabassum, Kiran Gangarapu, Gouthami Thumma, Sarangapani Manda, Rama Narsimha Reddy Anreddy

“…These observations enable us to conclude that N′′,N′′′-bis[5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]carbonohydrazide has cardioprotective activity against doxorubicin induced cardiotoxicity.…”
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