Diagnosis and Management of a Patient With Chronic Lymphocytic Leukemia and a Concurrent Plasmacytoma by Danielle C. Thor, Rohan Umrani, Jack Bergal, Charles Yang, Richard Gordon

“…Chronic lymphocytic leukemia (CLL) typically presents as an indolent disease with a benign disposition in most patients. …”
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Giant Fibrovascular Polyp of the Esophagus: A Novel Technical Approach by Juan José Trakál, Guillermo Jorge Sarquis, Juan Antonio Muñoz, Sergio Barril, Esteban Trakál, Lucas Armando, Rosa Carolina Gorordo Ipiña

“…Fibrovascular polyps (FVPs) of the esophagus are rare, and their course is usually indolent until reaching enormous proportions. It is a dramatic entity owing to its tendency to cause bizarre complications. …”
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Primary Pancreatic Hepatoid Carcinoma: A Case Report and Literature Review by Tyng-Wei Yang, Hsiang-Fong Kao*

“…We report a case with a long indolent course of primary pancreatic hepatoid carcinoma (PHC) before curative surgery, with an estimated doubling time of 429 days. …”
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Bacillus pumilus Septic Arthritis in a Healthy Child by V. M. Shivamurthy, Soren Gantt, Christopher Reilly, Peter Tilley, Jaime Guzman, Lori Tucker

“…This child developed an indolent joint swelling after a minor skin injury, and symptoms were initially thought most consistent with chronic arthritis. …”
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Paediatric extra-axial myxopapillary ependymoma: what to expect? Case report and literature review by Roberto Lo Piccolo, Roberto Lo Piccolo, Maria Chiara Cianci, Iacopo Sardi, Marco Di Nicola, Anna M. Buccoliero, Chiara Caporalini, Antonino Morabito, Antonino Morabito

“…The current report presents a case of extra-axial MPE in a paediatric patient who presented with an indolent sacral mass and underwent surgical resection, along with a review of the literature. …”
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Chronic Lymphocytic Leukemia as an Unusual Cause of Rapid Airway Compromise by Adrian R. Bersabe, Joshua T. Romain, Erin E. Ezzell, John S. Renshaw

“…Chronic Lymphocytic Leukemia (CLL) is the most prevalent form of non-Hodgkin’s lymphoma (NHL) in Western countries predominantly affecting adults over the age of 65. CLL is commonly indolent in nature but can present locally and aggressively at extranodal sites. …”
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CNS Vasculitis Associated with Waldenström Macroglobulinemia by Tanawan Riangwiwat, Chris Y. Wu, Alberto S. Santos-Ocampo, Randal J. Liu, Aaron M. McMurtray, Beau K. Nakamoto

“…Waldenström macroglobulinemia (WM) is an indolent B cell lymphoproliferative disorder with monoclonal IgM secretion. …”
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Subcutaneous Leiomyosarcoma of the Frenulum by D. Mendis, S. R. J. Bott, J. H. Davies

“…We record the case of a patient who presented with a 2-year history of a seemingly indolent penile skin lesion. On histopathology of the local resection, a diagnosis of subcutaneous leiomyosarcoma was made. …”
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Intracapsular Enucleation of Intraparotid Facial Nerve Schwannoma with Intratemporal Extension by Linger SIM, Xing Yi YEOH, Tay Eng TAN, Zahirrudin ZAKARIA, Irfan MOHAMAD

“…Considering the benign indolent nature of the schwannomas, the management should be prioritized on the long-term tumor control with special attention to the facial nerve function and facial cosmesis. …”
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The South African Prostate Cancer Screening Guidelines by J John, A Adam, L Kaestner, P Spies, S Mutambirwa, J Lazarus

“…Identifying and treating men with clinically significant disease while avoiding the over-diagnosis and over-treatment of indolent disease remains a significant challenge. Several professional associations have developed guidelines on screening and early diagnosis of asymptomatic men with prostate-specific antigen testing. …”
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Primary Renal Carcinoid with Bilateral Multiple Clear Cell Papillary Renal Cell Carcinomas by Daniel A. Anderson, Maria S. Tretiakova

“…Clear cell papillary renal cell carcinoma (CCPRCC) is a newly recognized entity in the 2016 WHO classification and usually presents as a small, circumscribed, solitary mass of indolent nature. CCPRCCs could seldom occur in conjunction with other synchronous or metachronous kidney tumors and even less frequently as bilateral masses. …”
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Ureteritis Cystica Presenting with Atrophic Kidney: Report of a Case by Ayca Tan, Saime Unluoglu, Umit Bayol, Sehnaz Emil Sayhan, Deniz Altinel

“…In conclusion, ureteritis cystica is a benign and indolent lesion that needs to be kept in mind among the causes of renal atrophy.…”
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Voluminous Extracardiac Adult Rhabdomyoma of the Neck: A Case Presentation by Riccardo Maglio, Scicchitano Francesco, Magistri Paolo, Valabrega Stefano, D'Angelo Francesco, Ramacciato Giovanni

“…We report a case of voluminous extracardiac adult rhabdomyoma affecting adult patients and initially seen as slowly growing, indolent neoplasms. The patient is a seventy-year old male Italian patient. …”
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Hepatic Actinomycosis with Infiltration of the Diaphragm and Right Lung: A Case Report by Tasbirul Islam, Muhammad Nauman Athar, Muhammad Kamran Athar, Mohammed Haris Umer Usman, Baqir Misbah

“…Actinomycosis is an indolent, slowly progressive infection caused by anaerobic or microaerophilic bacteria of the genus Actinomyces. …”
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Emergency radiological evaluation of wandering spleen volvulus and infarction: A case report and review of literature by Muataz Kashbour, MBChB, Maaly Abuhlaiga, MBChB, Muhammed Asim Awan, MD, Khalid Gashoot, MD

“…The diagnosis of WS in the emergency department poses a particular clinical challenge as the clinical presentation is highly variable from acute abdomen requiring immediate surgery to chronic indolent pain extending over years. Herein, we report the case of a 34-year-old nulliparous lady, who presented to the emergency department with left iliac fossa pain associated with vomiting, successfully diagnosed preoperatively using computerized tomography. …”
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Successful Treatment by Surgery and Lenvatinib of a Patient with Adrenal Metastasis of Papillary Thyroid Cancer by Hajime Nakamura, Kohichi Takada, Kazuyuki Murase, Hiroki Sakamoto, Naotaka Hayasaka, Kazuma Ishikawa, Yuki Ikeda, Makoto Yoshida, Satoshi Iyama, Ko Kobayashi, Tetsuya Shindo, Shintaro Sugita, Koji Miyanishi, Masayoshi Kobune, Naoya Masumori, Junji Kato

“…Papillary thyroid cancer (PTC) is considered an indolent cancer, but some PTC patients do present with distant metastases and treatment strategies for such patients are not well established. …”
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Surgical Treatment of Liver Metastases in Neuroendocrine Neoplasms by Palepu Jagannath, Deepak Chhabra, Shailesh Shrikhande, Rajiv Shah

“…An aggressive approach should be used to resect the primary tumor, to remove regional lymph nodes, and to resect or treat appropriate distant metastases (including liver tumors). Despite having an indolent course, NENs have a significantly reduced survival when liver metastases are untreated. …”
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Clinical Implications for the Timely Diagnosis of Mycobacterium marinum in the Age of Biologic Therapy: A Case Report and Review of the Literature by Chris J. Lata, Kelle Edgar, Stephen Vaughan

“…A detailed exposure history and high degree of suspicion for this indolent pathogen are often required for the correct diagnosis of this disease. …”
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CAR-T therapy for endocrine neoplasms: novel targets and combination of therapies by Fang Wang, Ruiqi Zhang, Zhaokai Zhou, Run Shi, Fu Peng, Yudi Xu, Shuai Yang, Zhan Wang, Pengpeng Zhang, Rui Tu, Chun Zhang, Xingchen Liu, Jun Cai

“…Endocrine malignancies constitute a heterogeneous tumour group with diverse biological characteristics. While typically indolent, they encompass aggressive types and presence of any metastatic sign indicates a high probability of recurrence and a diminished response to conventional therapies. …”
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Pulmonary Alveolar Microlithiasis: A Unique Case of Familial PAM Complicated by Transplant Rejection by Austin Helmink, Samir Atiya, Ernesto Martinez Duarte

“…PAM is a rare lung disease caused by a mutation in the SLC34A2 gene, which encodes for a sodium-phosphate cotransporter in type II alveolar cells, leading to accumulation of intra-alveolar phosphate causing microlith formation. PAM has an indolent course but can progress to chronic hypoxic respiratory failure, ultimately requiring lung transplant, the only known effective treatment.…”
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