At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…The use of virtual reality (VR) exergames may offer a potential solution to the problem of increasing noncommunicable disease prevalence, as it can help individuals increase their physical activity levels while providing a more immersive experience. …”
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The Effectiveness of pen‒culture construction for cultivation of sea cucumber by Pitjont Tomatala, Petrus Paulus Letsoin, Evangelin Martha Yulia Kadmaer

“…The two of cultivated containers tested were a conventional pen‒culture (treatment A) and engineered pen‒culture (treatment B). A total of 30 individuals sea cucumber seeds sized 4‒6 cm were released at each pen‒culture. …”
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Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy by Gregory B. Lesinski, Chrystal M. Paulos, Maggie Phillips, Jacklyn Hammons, Isaac Karpovsky, Zaid Mahdi, Natalie K. Horvat, Megan M. Wyatt, Margaret A. Hall, Cameron J. Herting, Richard A. Moffitt

“…However, these models have limitations, including marked tumor variability across individual mice and the cost of colony maintenance.Methods Using flow cytometry and immunohistochemistry, we characterized the immunological features and trafficking patterns of adoptively transferred T cells in orthotopic PDAC (C57BL/6) models using two mouse cell lines, KPC-Luc and MT-5, isolated from C57BL/6 KPC-GEMM (KrasLSL-G12D/+p53−/− and KrasLSL-G12D/+p53LSL-R172H/+, respectively).Results The MT-5 orthotopic model best recapitulates the cellular and stromal features of the TME in the PDAC GEMM. …”
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The Effect of using the Smartphone in the Workplace on Job Engagement and Job Burnout: Investigation of Mediational Role of Stress by Somayeh Naghdi Zarrin, Neda Mohammad Esmaeili

“…Objective In today's rapidly evolving digital era, the prevalence of smartphone usage among individuals in various contexts, including both social and professional environments, is witnessing a remarkable increase. …”
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Impact of interpregnancy weight change on the risk of gestational diabetes mellitus during a second pregnancy in Chinese population: a retrospective cohort study by Ying Wang, Juan Yang, Chang Xu, Yuzhen Liu, Ao Yang, Shilin Zhong

“…IPWC < −1 kg/m² was not significantly associated with s-GDM either in the overall analysis or in the stratified analysis (p>0.05).Conclusion An IPWC of 3 kg/m² or higher may increase the risk of s-GDM, particularly among women with an IPI of less than 36 months, those under 35 years old, individuals without diabetes, or those with normal weight during their first pregnancy. …”
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Ultrasound-based radiomics and clinical factors-based nomogram for early intracranial hypertension detection in patients with decompressive craniotomy by Zunfeng Fu, Lin Peng, Laicai Guo, Chao Qin, Yanhong Yu, Jiajun Zhang, Yan Liu

“…It shows promise for enhancing non-invasive ICP monitoring and supporting individualized therapeutic strategies.…”
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Examining the Effect of Prototypical Leadership Style on Leader Effectiveness: Mediating role of Perceived Integrity and Moderating Role of Leader-leader Exchange by Elham Ebrahimi, SHabnam Zarjou

“…A statistical sample of 293 individuals was selected based on the tests used and G-Power software. …”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway by Xing Luo, Yi Duan, Jinwei He, CongGai Huang, Jun Liu, Yifan Liu, Mengdei Xu, Qiong Dai, Zhihui Yang

“…BackgroundThe Food and Drug Administration has approved the Serine/threonine-protein kinase B-raf (BRAF) inhibitor and Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitor combo as the first-line treatment for individuals with metastatic melanoma, although the majority of these patients exhibit primary or secondary drug resistance in the clinic. …”
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Medication patterns and potentially inappropriate medication in patients with metastatic breast cancer: results of the BRE-BY-MED study by Lilly Sophia Brandstetter, Anna Grau, Peter U. Heuschmann, Max Müller-Reiter, Jessica Salmen, Stefan Störk, Achim Wöckel, Jens-Peter Reese

“…Methods Between July 2022 and February 2024 individuals with advanced or mBC, aged ≥ 18 years, living in Bavaria, and who gave written informed consent, were included in the BRE-BY-MED “Breast Cancer Care in Bavaria for Patients with Metastatic Disease” cohort study (DRKS00026601). …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…We gathered demographic and clinical data, calculated UHR, and explored its correlation with DR development.Outcomes: Individuals diagnosed with diabetic retinopathy (DR) exhibited a markedly elevated uric acid to high-density lipoprotein cholesterol (UHR) ratio when contrasted with those without DR (NDR), achieving statistical significance with a P-value below 0.001. …”
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Influence of religion and spirituality on head and neck cancer patients and their caregivers: a protocol for a scoping review by Maheeka Seneviwickrama, Ruwan Jayasinghe, Kehinde Kazeem Kanmodi, Simon N. Rogers, Su Keill, Sakuntha Ratnapreya, Sriyani Ranasinghe, Sashini Shehana Denagamagei, Irosha Perera

“…Abstract Introduction Head and neck cancers (HNC) are devastating, thus imposing a negative impact on the appearance of an individual as well as vital activities such as eating, swallowing, speaking, and breathing. …”
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Providing a General Model for the Successful Implementation of Digital Transformation in Organizations by Haidar Ahmadi, Najme Parsaei, Seyyed Hamed Hashemi, Hamidreza Nematollahi

“…Data collection was primarily conducted through semi-structured interviews with 15 individuals until theoretical saturation was achieved. …”
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Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations by D. E. Ivanoshchuk, S. V. Mikhailova, O. G. Fenkova, E. V. Shakhtshneider, A. Z. Fursova, I. V. Bychkov, M. I. Voevoda

“…None of the detected mutations were found in the control sample of ophthalmologically examined individuals without PCG (100 people). Variants R444* (rs377049098) and R444Q (rs72549376) were not found in the general population sample either (576 randomly selected West Siberia residents). …”
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Refinement of a meaning-centered counseling program for Chinese patients with advanced cancer: integrating cultural adaptation and implementation science approaches by Florence Lui, Qingyi Zhang, George Chengxi Bao, Bharat Narang, Ruo Yan Chen, Yunshan Niu, Jennifer Leng, William Breitbart

“…Conclusion Recommendations for next steps include increasing the MCP-Ch protocol’s flexibility and adaptability to allow interventionists to flexibly tailor MCP-Ch material to meet patients’ individual needs, simplifying content to improve comprehension and acceptability, providing additional training to Chinese-serving providers to increase adoption and sustainability, and considering interpreter-assisted delivery to increase access. …”
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Comparison of brain activity metrics in Chinese and Russian students while perceiving information referencing self or others by Q. Si, J. Tian, V. A. Savostyanov, D. A. Lebedkin, A. V. Bocharov, A. N. Savostyanov

“…Using this module, brain electrical activity (EEG) indicators reflecting individual characteristics of recognition of information related to oneself and other people were compared between groups of 30 Chinese (14 men and 16 women, average age 23.2 ± 0.4 years) and 32 Russian (15 men, 17 women, average age 22.1 ± 0.4 years) participants. …”
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Physically based modelling of glacier evolution under climate change in the tropical Andes by J. D. Mackay, J. D. Mackay, N. E. Barrand, D. M. Hannah, E. Potter, E. Potter, N. Montoya, W. Buytaert

“…We show that the JULES–OGGM model can be parameterized to capture decadal (2000–2018) mass changes in individual glaciers, but we also show that limitations in the JULES prognostic snow model prevent accurate replication of observed surface albedo fluctuations and mass changes across all glaciers simultaneously. …”
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Identity Construction and Transformation of Zen Tourists by Xu Haichao, Liang Zengxian

“…"Identity contextualization" and "contextualization of space" are the two stages when Zen tourists return to the real world, leaving the religious Zen sites, corresponding to individual identity maintenance and identity constraints. …”
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The Effect of Colloids versus Crystalloids for Goal-Directed Fluid Therapy on Prognosis in Patients Undergoing Noncardiac Surgery: A Meta-Analysis of Randomized Controlled Trials by Wang Niu, Junyi Li, Shouping Wang

“…However, considering the individual characteristics of colloids and crystalloids in clinical use, it is uncertain as to which type of fluids administered is associated with better outcomes in the condition of GDFT. …”
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Barriers and drivers to exclusive breastfeeding in Kyrgyzstan: a qualitative study with mothers and health workers by Cath Jackson, Marina Duishenkulova, Nurila Altymysheva, Jyldyz Artykbaeva, Raisa Asylbasheva, Eleonora Jumalieva, Anastasia Koylyu, Sian Lickess, Tursun Mamyrbaeva, Veerle Snijders, Julianne Williams, Tiina Likki

“…Conclusions This theory-informed qualitative study focusing on mother and health worker perspectives provided important insights into the individual and contextual barriers and drivers to exclusive breastfeeding for the first six months in Kyrgyzstan. …”
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Barriers and Facilitators to the Preadoption of a Computer-Aided Diagnosis Tool for Cervical Cancer: Qualitative Study on Health Care Providers’ Perspectives in Western Cameroon by Magali Jonnalagedda-Cattin, Alida Manoëla Moukam Datchoua, Virginie Flore Yakam, Bruno Kenfack, Patrick Petignat, Jean-Philippe Thiran, Klaus Schönenberger, Nicole C Schmidt

“…Focus group discussions were conducted with midwives, while individual interviews were conducted with gynecologists to comprehend unique perspectives. …”
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