COMBINED TREATMENT OF LOCALLY-ADVANCED BLADDER CANCER by I. V. Chernyshev, Y. V. Samsonov, D. V. Perepechin, A. M. Ulbashev

“…There is an increasing proportion of detection of bladder cancer stage I–II disease patterns: 2003–50.8% in 2013–69.6%, while the number of newly diagnosed patients in III and IV clinical stages remains at 30%. The proportion of individuals who completed the treatment of the number of newly diagnosed patients with bladder cancer in 2013, was as follows: only surgical method — 65.4%, 33.5% combined. …”
Get full text

Psychological responses to acute exercise in patients with stress-induced exhaustion disorder: a cross-over randomized trial by Jenny Kling, Robert Persson Asplund, Örjan Ekblom, Victoria Blom

“…Conclusions A 22-min exercise session was perceived as more strenuous by patients with exhaustion disorder (ED) and generated greater improvements in feelings of fatigue, energy, and stress compared to healthy individuals without delayed negative effects. These findings highlight the specific psychological responses in ED to exercise and can inform intervention design tailored specifically to this population. …”
Get full text

Emergency Physicians’ and Nurses’ Perspectives on Transgender, Intersexual, and Non-Binary Patients in Germany by Torben Brod, Carsten Stoetzer, Christoph Schroeder, Stephanie Stiel, Kambiz Afshar

“…Introduction: Providing appropriate healthcare for transgender, intersexual and non-binary (TIN) individuals remains a significant challenge, as this group experiences higher rates of health inequalities, discrimination, and barriers to accessing care. …”
Get full text

The Social Construction of Categorical Data: Mixed Methods Approach to Assessing Data Features in Publicly Available Datasets by Theresa Willem, Alessandro Wollek, Theodor Cheslerean-Boghiu, Martha Kenney, Alena Buyx

“…However, the effects of including categorical data features for model training in such data-scarce areas are underexamined, particularly regarding models intended to serve individuals equitably in a diverse population. …”
Get full text

Differentiation of <i>Bos grunniens</i> and <i>Bos taurus</i> based on STR locus polymorphism by K. B. Chekirov, Zh. T. Isakova, V. N. Kipen, M. I. Irsaliev, S. B. Mukeeva, K. A. Aitbaev, G. A. Sharshenalieva, S. B. Beyshenalieva, B. U. Kydyralieva

“…Bos grunniens and Bos taurus differentiation based on STR locus polymorphism will help maintain the genetic isolation of these species and identify hybrid individuals. The aim of this study is to assess the differentiating potential of 15 microsatellite loci to distinguish between domestic yak (B. grunniens) bred in the Kalmak-Ashuu highland region (Kochkor district, Naryn region, Kyrgyz Republic) and cattle (B. taurus) of three breeds (Aberdeen-Angus, Holstein and Alatau) using molecular genetic analysis. …”
Get full text

Assessment of COVID-19 vaccine uptake and associated factors among healthcare workers in selected health facilities of the Somali Region, Eastern Ethiopia: a cross-sectional study... by Maereg Wolde, Trhas Tadesse Berhe, Addisalem Melesse, Rachana Sharma, Hnin Su Mon, Tesfaye Simireta, Hailemariam Addisu, Yosef Wassihun

“…Participants who were concerned about the availability of the COVID-19 vaccine were less likely to receive it than individuals who were not concerned (AOR 0.01; 95% CI (0.002 to 0.052)).Conclusion The vaccination uptake among HCWs in the region was relatively low, with the type of profession and concerns about vaccine availability being significant factors affecting the uptake.…”
Get full text

Lipoprotein (a) levels in children with heterozygous familial hypercholesterolemia by Liliya F. Galimova, Dinara I. Sadykova, Evgeniia S. Slastnikova, Chulpan D. Khaliullina, Karina R. Salakhova

“…The analysis revealed a significantly increased Lp(a) levels in FH patients (14.8 [6.3–24.3] mg/dL) compared to the control group (10.8 [5.5–14.8] mg/dL, p=0.0002). An individual serum Lp(a) analysis in the study and control groups showed that no healthy children had Lp(a) levels above 30 mg/dL. …”
Get full text

Participant Compliance With Ecological Momentary Assessment in Movement Behavior Research Among Adolescents and Emerging Adults: Systematic Review by Shirlene Wang, Chih-Hsiang Yang, Denver Brown, Alan Cheng, Matthew Y W Kwan

“…Ecological momentary assessment (EMA) is an innovative method involving real-time assessment of individuals’ experiences and behaviors in their naturalistic or everyday environments; however, EMA compliance can be problematic due to high participant burdens. …”
Get full text

Evaluation of Delay Characteristics at A 4- Legged Signalised Intersection for Improvement in The Level of Service. A Case Study of Jinja Road Intersection. by Babirye, Joanitor

“…The VISSIM model is an advanced micro- simulation tool with capabilities of modelling both intersection and traffic signals to acceptable level of detail. the model’s ability is to capture the effects of various geometric and traffic features like number of lanes, position of the stop line and proportion of turning flows, and evaluates their impacts on the resulting capacities and delay. Motion of an individual vehicle is simulated in small time steps and each vehicle is followed from the time it is generated into the network to the point of its exit. …”
Get full text

Factors Responsible For School Dropout At Different Levels of Education in Selected Academic Institutions in Kisoro Municipality Southern Division Kisoro District. by Kamahoro, Phionah

“…A cross-sectional research design was used to generate the information by explaining to the individual respondents the gist of the study. The population of the Study included SMC members, municipality education officials, head teachers, and their deputies, students, and teachers. …”
Get full text

Effects of Agrochemicals on Soil Bio-Physico-Chemical Properties in Potato Production Systems in the Highlands of South Western Uganda. by Twebaze, Jeniffer

“…Termites were significantly higher than other macro-organisms (p<0.05), but for the rest of the organisms (earthworms, beetles, and millipedes), there were no significant differences in individual populations (p>0.05). The findings of the study further revealed that the majority of potato farmers (>90%) rely on the use of agrochemicals. …”
Get full text

Factors Affecting the Teaching and Learning of English Language in Primary Schools in Kitumba Sub-County Kabale District. by Owomugisha, Justine

“…The findings obtained in the study indicated that the effect of the factors affecting the teaching and learning of English in Primary schools were reduced access to quality learning resources, ineffective teaching methods, poor Pupil outcomes, lack of support at home, decreased motivation, limited individual attention, poor classroom control, difficulty in comprehension, slower language acquisition, challenges in curriculum delivery, teacher frustration and distraction. …”
Get full text

Cerebral Cortical Activity During Academic Stress Amongst Undergraduate Medical Students at Kampala International University (Uganda) by Mujinya, Regan, Kalange, Muhamudu, Ochieng, Juma John, Ninsiima, Herbert Izo, Eze, Ejike Daniel, Afodun, Adam Moyosore, Nabirumbi, Ritah, Sulaiman, Sheu Oluwadare, Kairania, Emmanuel, Echoru, Isaac, Okpanachi, Alfred Omachonu, Matama, Kevin, Asiimwe, Oscar Hilary, Nambuya, Grace, Usman, Ibe Michael, Obado, Osuwat Lawrence, Zirintunda, Gerald, Ssempijja, Fred, Nansunga, Miriam, Matovu, Henry, Ayikobua, Emmanuel Tiyo, Nganda, Ponsiano Ernest, Onanyang, David, Ekou, Justine, Musinguzi, Simon Peter, Ssimbwa, Godfrey, Keneth Iceland, Kasozi

“…Also, highly stressed individuals had higher TRT and ART and low VRT. SS had high VRT and ART and low TRT in preclinical students, demonstrating the importance of the visual cortex in stress plasticity. …”
Get full text

A phenomenological study of knowledge concealment in country water and sewage engineering company by Gholamreza Moghadasi, Hamidreza Rezaei Kelidbari, Mohammad Doostar

“…Van & Hoff (2017) argued that knowledge hiding occurs when an individual does not intentionally disseminate his knowledge to other members of the organization (Kang et al, 2017; Hernaus et al, 2016). …”
Get full text

Against Futility Judgments for Patients with Prolonged Disorders of Consciousness by William Choi

“…However, these beliefs can be predicated on prejudiced perceptions about the quality of life of individuals with disabilities or chronic illnesses, a phenomenon commonly referred to as the disability paradox.[11] The paradox describes the discrepancy between patients with disabilities who report a quality of life much higher than non-disabled individuals would predict their ratings. …”
Get full text

A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen by Saubin, Méline, Coville, Jérome, Xhaard, Constance, Frey, Pascal, Soubeyrand, Samuel, Halkett, Fabien, Fabre, Frédéric

“…However, accurately inferring LDD is challenging as it requires both large-scale data and a methodology that encompasses the redistribution of individuals in time and space. Here, we propose a mechanistic-statistical framework to estimate dispersal from one-dimensional invasions. …”
Get full text

Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

“…Interestingly, methanogen archaeas exhibited the strongest positive associations with cognition, particularly Methanobrevibacter smithii (M. smithii). Stratifying individuals by median-centered log ratios (CLR) of M. smithii (low and high M. smithii groups: LMs and HMs) revealed that HMs exhibited better cognition and distinct gut bacterial profiles (PERMANOVA p = 0.001), characterized by increased levels of Verrucomicrobia, Synergistetes and Lentisphaerae species and reduced levels of Bacteroidetes and Proteobacteria. …”
Get full text

Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

“…Objective To characterise the association between duration of exposure to antiretroviral treatment (ART) and liver damage in HIV patients with an initially normal baseline liver function and without hepatitis B virus (HBV)/hepatitis C virus (HCV) infection.Methods A retrospective cohort study was conducted in HIV-infected individuals with normal liver function parameters at ART initiation and without HBV/HCV infection, from 14 April 2004 to 13 April 2015 in Guigang city, Guangxi, China. …”
Get full text

CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids by Alexander Hennig, Laura Wolf, Beatrix Jahnke, Heike Polster, Therese Seidlitz, Kristin Werner, Daniela E. Aust, Jochen Hampe, Marius Distler, Jürgen Weitz, Daniel E. Stange, Thilo Welsch

“…Organoid cultures of human pancreatic ductal adenocarcinoma (PDAC) have become a promising tool for tumor subtyping and individualized chemosensitivity testing. PDACs have recently been grouped into different molecular subtypes with clinical impact based on cytokeratin-81 (KRT81) and hepatocyte nuclear factor 1A (HNF1A). …”
Get full text

Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma by Li Yan, Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj, Kathryn Graz, Elnaz Naderi, Jianhong Chen, Mourad Wagdy Ali, Puya Gharahkhani, Xiang Shu, Kenneth Offit, Pari M. Shah, Hans Gerdes, Daniela Molena, Amitabh Srivastava, Stuart MacGregor, Claire Palles, René Thieme, Michael Vieth, Ines Gockel, Thomas L. Vaughan, Johannes Schumacher, Matthew F. Buas

“…The strongest evidence for secondary replication was for rs17744726×rs3217992 among males, with consistent directionality across all cohorts (Pmeta = 2.19 × 10−8); rs3217992 “T” was associated with reduced risk only in individuals homozygous for rs17744726 “G.” Rs3217992 maps to the CDKN2B 3′ UTR and reportedly disrupts microRNA-mediated repression. …”
Get full text