Genetic trends and common BRCA1/2 pathogenic sequence variants in black African and Indian breast cancer patients presenting at Inkosi Albert Luthuli Central Hospital, KwaZulu-Nata... by M Makhetha, C Aldous, N Chabilal

“…Indians represented 50% of bilateral breast cancers and of high-risk individuals. We identified 30 pathogenic BRCA1/2 sequence variants, four large genomic rearrangements and 13 variants of unknown significance. …”
Get full text

Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Introduction Primary hypertension (PH) affects over one billion individuals globally, yet less than 30% achieve controlled blood pressure (BP) with medication. …”
Get full text

Association between Metformin and a Lower Risk of Age-Related Macular Degeneration in Patients with Type 2 Diabetes by Yu-Yen Chen, Ying-Cheng Shen, Yun-Ju Lai, Chun-Yuan Wang, Keng-Hung Lin, Shih-Chao Feng, Chiao-Ying Liang, Li-Chen Wei, Pesus Chou

“…Among patients with type 2 diabetes, those who use metformin are at a significantly lower risk of developing AMD relative to individuals who do not use metformin. Also, the trend of a significantly lower AMD risk was found with a higher dose of metformin.…”
Get full text

Espectro hospedador, prevalencias y dispersión del entonompatógeno Paranosema locustae (Microsporidia) en tucuras (Orthoptera: Acridoidea) del sudoeste de Buenos Aires by Carlos E. Lange, Maria L. de Wysiecki

“…En el laboratorio, se examinaron en forma individual por homogenización o disección para detectar la presencia de Paranosema locustae, un agente para el control biológico de tucuras a largo plazo. …”
Get full text

Mortality and Its Predictors among Adult Human Immune-Deficiency Virus-Infected Patients Attending Their Antiretroviral Treatment at Health Centers, Addis Ababa, Ethiopia: Multicen... by Selam Tesfayohannes, Sisay Shine, Abinet Mekuria, Sisay Moges

“…Adult HIV-positive individuals had an incidence of the death rate of 55 (8.5%), which equates to 3.25 deaths per 100 person-years. …”
Get full text

Prevalence of mortality caused by injuries at Livingstone University Hospital, Zambia. A retrospective cross-sectional study. by Lukundo Siame, Malan Malumani, Chiyeñu O R Kaseya, Sergiy Ivashchenko, Leah Nombwende, Sepiso K Masenga, Benson M Hamooya, Michelo Haluuma Miyoba

“…<h4>Methods</h4>We conducted a retrospective cross-sectional study from June 22, 2020, to June 22, 2021, among 956 individuals from 1 month old (29 days of age) to 100 years. …”
Get full text

Metabolite profiling in assessing ulcerative colitis activity: A systematic review by Danyang Cui, Xu Han, Jiazhu Jin, Yanhong Wang, Zijia Chen, Yang Gong, Miao Jiang

“…Previous systematic reviews have focused on metabolite analysis between UC patients and healthy individuals, but have not systematically evaluated metabolite changes in different disease stages. …”
Get full text

Diagnosis of lung cancer using salivary miRNAs expression and clinical characteristics by Negar Alizadeh, Hoda Zahedi, Maryam Koopaie, Mahnaz Fatahzadeh, Reza Mousavi, Sajad Kolahdooz

“…Conclusion A salivary miRNA-based MLR model is a promising diagnostic tool for lung cancer, offering a non-invasive screening option for high-risk asymptomatic individuals.…”
Get full text

Early selective attention to the articulating mouth as a potential female-specific marker of better language development in autism: a review by Itziar Lozano, Charlotte Viktorsson, Elena Capelli, Teodora Gliga, Valentina Riva, Przemysław Tomalski

“…Ultimately, we aim to target a novel protective candidate of language acquisition, informing tailored interventions that consider sex as an important source of individual variability.…”
Get full text

Quantitative Trait Loci Analysis of Folate Content in Dry Beans, Phaseolus vulgaris L. by S. Khanal, J. Xue, R. Khanal, W. Xie, J. Shi, K. P. Pauls, A. Navabi

“…These QTL had significant dominance effects and individually accounted for 7.7% to 10.5% of the total phenotypic variance. …”
Get full text

The Evaluation of Tau Deposition with [18F]PI-2620 by Using a Semiquantitative Method in Cognitively Normal Subjects and Patients with Mild Cognitive Impairment and Alzheimer’s Dis... by Attapon Jantarato, Sira Vachatimanont, Natphimol Boonkawin, Sukanya Yaset, Anchisa Kunawudhi, Chetsadaporn Promteangtrong, Jintana Assanasen, Nithi Mahanonda, Chanisa Chotipanich

“…Therefore, this study’s aim was to perform a semiquantitative analysis of [18F]PI-2620 in individuals with normal cognition and patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). …”
Get full text

Indirect treatment comparison of lanadelumab and a C1-esterase inhibitor in pediatric patients with hereditary angioedema by Maureen Watt, Rachel Goldgrub, Mia Malmenas, Katrin Haeussler

“…A propensity score analysis used individual patient-level data from both studies in a logistic regression model to estimate inverse probability weights. …”

La longévité des nids, un paramètre essentiel pour la détermination de la taille des populations de grands singes : Cas de bonobos dans la Réserve de Faune de Lomako-Yokokala en Ré... by Valentin Omasombo Wotoko, Aurélien Besnard, Claude Miaud, Jean Malekani, Julien Punga

“…Le taux de création des nids est le nombre de nids créés par un individu de l’espèce étudiée par jour; il est caractéristique de l'espèce et varie avec les saisons. …”
Get full text

Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level by Giusy Rita Maria La Rosa, Alejandro Ismael Lorenzo-Pouso, Vito Carlo Alberto Caponio, Mariangela Valentina Puci, Mariangela Valentina Puci

“…A meta-analysis was performed to determine the pooled prevalence and risk of AP at individual and tooth level and the quality of evidence was assessed by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. …”
Get full text

Validation of the REDS score in hospitalised patients who deteriorated and were admitted to the intensive care unit—a retrospective cohort study by Narani Sivayoham, Oliver Mason, Harriet O’Mara, Natasha Trenchard Turner, Katie Sysum, Georgina Wicks

“…Test characteristics at the cut-off points individually and in combination were noted.Results Of the 289 patients studied, 91 died. …”
Get full text

Observed upper-ocean structure and seasonal production in the southern Kerguelen Plateau region, 1994-2021 by Man Liang, Annie Foppert, Annie Foppert, Karen J. Westwood, Karen J. Westwood, Sophie Bestley, Sophie Bestley

“…Nutrient drawdown is calculated based on mean concentrations in the mixed layer and WW layer, with drawdown values at individual stations reaching nearly 12 µM and 60 µM for nitrate and silicate, respectively, and a positive correlation between the two. …”
Get full text

Efficacy of Olmesartan/Amlodipine Single‐Pill Combination on 24‐h Mean Systolic Blood Pressure Measured by Ambulatory Monitoring in Non‐Responders to Valsartan or Candesartan Monot... by Woo‐Baek Chung, Sang‐Hyun Ihm, Yun‐Seok Choi, Ho‐Joong Youn

“…Isolated systolic hypertension (ISH) is the most prevalent form of hypertension in middle‐aged and elderly individuals. Patients aged over 55 years who did not achieve the target systolic blood pressure (SBP < 140 mmHg) with valsartan 80 mg or candesartan 8 mg for at least 4 weeks were included. …”
Get full text

When Technology Meets Anxiety:The Moderating Role of AI Usage in the Relationship Between Social Anxiety, Learning Adaptability, and Behavioral Problems Among Chinese Primary Schoo... by Ma G, Tian S, Song Y, Chen Y, Shi H, Li J

“…This highlights the need for educators to focus on improving students’ learning adaptability, judiciously incorporate AI technology, and consider individual differences, particularly mental health, to foster comprehensive and healthy student development.Keywords: social anxiety, learning adaptability, AI usage, behavioral problems, primary school students…”
Get full text

Sex-specific alterations in creatine metabolism in cellular compartments of peripheral blood leukocytes in type 1 diabetes by Nina Alchujyan, Elena Aghajanova, Nina Movsesyan, Arthur Melkonyan, Artashes Guevorkian, Armen Andreasyan, Margarita Hovhannisyan

“…A group of healthy individuals that were matched for age and sex served as controls. …”
Get full text

Mixed Comparative Evaluation of a Training Program Dedicated to Cystic Fibrosis Reference Centers: Protocol for the Pilot Implementation of Shared Decision-Making in the Treatment... by Nora Moumjid, Constance Gotte, Sophie Hommey, Stéphanie Poupon Bourdy, Julie Haesebaert, Isabelle Durieu, Quitterie Reynaud

“…A qualitative analysis through observation of consultations, individual semistructured interviews with patients, and focus groups in CFRCs will be conducted based on a thematic content analysis. …”
Get full text