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17341
Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights
Published 2025-01-01“…Additionally, Receiver operating characteristic (ROC) curve analysis highlighted the significant (p-value < 0.05) diagnostic potential of MMP7, MMP11, and MMP14 in distinguishing SKCM from normal individuals. Subsequent validation across multiple cohorts confirmed significant (p-value < 0.05) elevated MMP expression levels in SKCM tissues, particularly in advanced disease stages, further emphasizing their role in tumor progression. …”
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17342
Relationship Between Serum HMGB1 and RAGE Levels and Restenosis in Type 2 Diabetes Mellitus Patients Complicated With Lower Extremity Vascular Disease: A Retrospective Study
Published 2025-02-01“…ROC curve analysis further emphasized the superior combined predictive value of HMGB1 and RAGE over individual biomarkers for restenosis after interventional therapy in this cohort.Conclusion: Elevated preoperative serum levels of HMGB1 and RAGE in T2DM patients with lower extremity vascular disease are linked to restenosis following interventional therapy.Keywords: type 2 diabetes mellitus, lower extremity vascular disease, interventional therapy, high mobility group protein B1, receptor of advanced glycosylation end-products…”
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17343
Impact of the severity and extension of dental caries lesions on Turkish preschool children’s oral health-related quality of life: a cross-sectional study
Published 2025-02-01“…Early detection and management of dental caries are crucial in improving the quality of life for affected individuals. Dental practitioners should prioritize preventive measures and parental education to mitigate the adverse effects of dental caries.…”
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17344
Telerehabilitation: A Practical Remote Alternative for Coaching and Monitoring Physical Kinetic Therapy in Patients with Mild and Moderate Disabling Parkinson’s Disease during the...
Published 2022-01-01“…Moreover, with modern telecommunication techniques, a regular and individualized physical kinetic rehabilitation program can be performed even in pandemic conditions. …”
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17345
Trends in <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Urinary Tract Infections and Antibiotic Resistance over a 5-Year Period in Southeastern Gabon
Published 2024-12-01“…<b>Conclusions:</b> UTIs show variability according to various sociodemographic, clinical, and climatic factors, with a higher risk of complications seen in individuals aged ≤ 17 years. It is important to note that cases of pyelonephritis have been increasing over time, with a noticeable seasonal variation. …”
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17346
Evaluation of an Interdisciplinary Educational Program to Foster Learning Health Systems: Education Evaluation
Published 2025-01-01“…This evaluation shed light on the multifaceted challenges and expectations of individuals embarking on a digital health program. Understanding the barriers and facilitators of the audience is crucial for creating an inclusive and supportive learning environment. …”
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17347
Application of machine learning algorithms in predicting new onset hypertension: a study based on the China Health and Nutrition Survey
Published 2025-01-01“…Methods: We analyzed data from the 2011 China Health and Nutrition Survey cohort of individuals who were not hypertensive at baseline and had follow-up results available for prediction by 2015. …”
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17348
Impact of cognition and psychoemotional status on falls in multiple sclerosis
Published 2020-12-01“…It is important to take into account not only physical disability as a risk factor for falls in multiple sclerosis but also psychoemotional factors, and to apply individual preventive measures, regardless of the patients’ age or disease duration. …”
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17349
Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China
Published 2025-02-01“…Therefore, this study aims to examine their relationship in older individuals with pre-frailty and frailty, respectively. …”
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17350
Profiles of Killer Systems and Volatile Organic Compounds of Rowanberry and Rosehip-Inhabiting Yeasts Substantiate Implications for Biocontrol
Published 2025-01-01“…Statistically significant differences between the individual VOCs were observed among killing phenotype-possessing vs. non-killer <i>S. paradoxus</i> yeasts, thus revealing the involvement of killer systems in multi-level biocontrol enablement. …”
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17351
Detection and subtyping of Blastocystis sp. in human and animal stool samples using high-resolution melting analysis
Published 2025-02-01“…Although the pathogenicity of Blastocystis remains debated, it has been detected in both symptomatic and asymptomatic individuals. Traditionally, direct microscopy with wet mounts is used for the rapid identification of Blastocystis in stool samples. …”
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17352
Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study
Published 2023-02-01“…In addition, less than 10% of individuals attributed vitamin D shortage to kidney and liver problems, fat malabsorption, obesity, and bariatric surgery. …”
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17353
Adaptation of the five-factor BFI-10 personality screening questionnaire and testing of its diagnostic properties on the example of drug users
Published 2021-12-01“…The obtained results prove that the proposed adaptation of BFI-10 meets the criteria of diagnostic reliability and validity, and can be recommended for express diagnosis of personality in terms of mass sample surveys and express individual screening of personality traits in the Ukrainian-speaking environment.…”
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17354
Pengembangan Aplikasi Fokus Timer Dengan Tracking Penggunaan Smartphone Menggunakan Pendekatan Gamifikasi
Published 2024-10-01“…The software development analysis involved identifying user needs through a questionnaire and interviews with 50 and 8 individuals, respectively.. This research adapts the waterfall method with the stage of literature study, analysis needs, design, implementation, testing and analysis, as well as conclusions and suggestions. …”
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17355
Cross-Sectional Survey to Assess Tobacco and Nicotine Product Use since the Introduction of Heated Tobacco Products in Japan: Wave 2
Published 2025-01-01“…Complete responses were available from 5307 individuals, of whom 889 (16.7%) were current users, 1012 (19.1%) were former users, and 3407 (64.2%) were never users of tobacco products (weighted respondent totals). …”
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17356
Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu.
Published 2025-01-01“…<h4>Methods</h4>In this hypothetical cohort of 100,000 individuals using the decision tree analysis, a cost-effectiveness assessment was conducted for both proposed and existing strategies. …”
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17357
Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time
Published 2025-01-01“…Accordingly, we hypothesized that sex differences in cardiovascular and ventilatory responses would be more pronounced with equal hypoxia duration (iso-time) but less pronounced at similar oxygen desaturation levels (iso-saturation).MethodsTwenty-two (12 females) healthy individuals were exposed to normoxia (10 min at FiO2 = 0.21) and hypoxia (10 min at FiO2 = 0.115), respectively. …”
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17358
Sources of economically valuable traits for winter triticale breeding in the northwest of the Russian Federation
Published 2019-01-01“…The three-year study (2015-2017) of the winter triticale collection material of different ecogeographic origin has resulted in the identification of genetic sources of individual important agronomic traits, such as early maturity (e.g., 'Don' (k-3637), 'Almaz' (k -3908), 'Proryv' (k-3763), 'Interes' (k-3968), 'Pshenichnoe' (k-3965), 'ADM-6' (k -3544), 'ADM-9' (k-3421), 'Utro' (k-3926)), dwarfness (e.g., 'Ramzaj' (k-4071), 'Samurai' (k-4072), 'Skif' (k-3931), 'Zavet' (k-4020), 'Proryv' (k-3763), 'Dozor' (k-4021), 'Knyaz'' (k-4076), 'L-372' (k-2806), 'Pshenichnoe' (k-3965), 'Kroha' (k-3929)), productivity (e.g., 'Impul's' (k- 3999), 'Prometey' (k-3900), 'Kvazar' (k-3938), 'Interes' (k-3968), 'Trizub' (k-3969), 'Papsuevskaya' (k-3924), 'Svityaz'' (k-3963), 'Topaz' (k-3909), 'Dawitol' (k-4002), 'Prado' (k-3865)), and disease resistance (e.g., 'PRAG 536' (k-3945), 'PRAG 456' (k-3946), 'Kvazar' (k-3938), 'Prometey' (k- 3900), 'Svyatozar' (k-3940), 'Yasha' (k-3912)). …”
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17359
Association between vitamin D levels and preserved ratio impaired spirometry: an investigation of mediating roles of systemic inflammation and metabolic indicators
Published 2025-01-01“…National Health and Nutrition Examination Survey, including 1,577 individuals with PRISm and 15,756 without. Baseline characteristics were assessed, and multivariate logistic regression models were employed to examine the relationship between vitamin D and PRISm. …”
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17360
Immunohistochemical Expression of AQP2 and HSP70 in Broiler Kidney Tissue Treated with Salix tetrasperma Roxb. Extract under Heat Exposure
Published 2021-01-01“…Chickens were kept in individual cages, provided with feed and drinking water ad libitum. …”
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