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17161
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression
Published 2025-01-01“…Results Elevated expression levels of FadA, ANXA2, hsa-let-7a-2, and LINC00460 were observed in CRC specimens, followed by AP cases, in comparison to samples from normal individuals. Application of the Spearman test revealed a strong and significant correlation between FadA and LINC00460 (rS = 0.9311, p < 0.0001). …”
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17162
Discrimination of Selected Cold-Pressed and Refined Oils by Untargeted Profiling of Phase Transition Curves of Differential Scanning Calorimetry
Published 2023-08-01“…PCA demonstrated a clear separation between refined and cold-pressed oils as well as six individual oils. The OPLS-DA showed a distinct classification in six classes according to the types of oils. …”
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17163
Body composition as an indicator of metabolic changes in mice obtained by <i>in vitro</i> fertilization
Published 2023-07-01“…At the same time, IVF offspring outperformed control individuals in relative fat content, but were behind in terms of lean mass. …”
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17164
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…Interstitial cystitis is a fierce syndrome affecting the quality of life of thousands of individuals around the globe. It causes immense pain in the bladder and associated viscera along with inflammation-like lesions. …”
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17165
Estimating the global health impact of gender-based violence and violence against children: a systematic review and meta-analysis protocol
Published 2022-06-01“…Data will be extracted using a standardised form with fields to capture study characteristics and estimates of association between violence exposure and health outcomes. Individual study quality will be assessed via six risk of bias criteria. …”
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17166
Association between the ABCC11 gene polymorphism-determined earwax properties and external auditory canal microbiota in healthy adults
Published 2025-02-01“…We analyzed ABCC11 gene polymorphisms and ear canal microbiota in healthy individuals to understand the relationship between genome–microbiome interactions in the ear canal. …”
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17167
Lipid Levels and Lung Cancer Risk: Findings from the Taiwan National Data Systems from 2012 to 2018
Published 2025-01-01“…Abstract Background Lipids are known to be involved in carcinogenesis, but the associations between lipid profiles and different lung cancer histological classifications remain unknown. Methods Individuals who participated in national adult health surveillance from 2012 to 2018 were included. …”
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17168
Socioeconomic characteristics and relapse-free and overall survival from childhood cancer – a nationwide study based on data from the Danish Childhood Cancer Registry
Published 2025-01-01“…Parents, with whom the children resided, were identified, and data on the parents’ education, cohabitation status, affiliation to work market, country of origin, and vital status of the children were obtained through individual-level linkage across Danish nationwide registries. …”
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17169
Joint effect of modifiable risk factors on Parkinson’s disease: a large-scale longitudinal study
Published 2025-01-01“…The top 5 factors were hand grip strength (hazard ratio (HR) = 0.98, p = 1.59 × 10−24), long-standing illness (HR = 1.38, p = 3.63 × 10−20), self-reported nervousness (HR = 1.56, p = 5.9 × 10−20), ever suffered from mental health concerns (HR = 1.42, p = 5.48 × 10−18) and chest pain (HR = 1.42, p = 1.43 × 10−18). Individuals with unfavorable medical history, psychosocial factors, physical measures, and lifestyle had an increased risk of PD by 33 to 51% compared to those with favorable factors (p < 0.001).DiscussionResults indicated that addressing modifiable risk factors, especially in physical measures and psychological factors, could potentially prevent up to 33.87% of PD cases. …”
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17170
Prevalence of thyroid diffuse goiter and its association with body mass index and the presence of cysts and nodules in children and adolescents: the Fukushima Health Management Sur...
Published 2024-04-01“…The age-dependent increase in the prevalence of diffuse goiter was independently associated with increased BMI and positive prevalence of nodules in young individuals.…”
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17171
Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity
Published 2018-01-01“…The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. …”
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17172
Efficacy and safety of glucagon-like peptide-1 receptor agonists in the elderly versus non-elderly patients with type 2 diabetes mellitus: insights from a systematic review
Published 2024-06-01“…This systematic review aimed to compare the influence of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on the efficacy and safety of elderly patients with type 2 diabetes and younger individuals. A comprehensive search of PubMed, Embase, and Web of Science databases was conducted up to September 2022. …”
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17173
Structural damage-driven brain compensation among near-centenarians and centenarians without dementia
Published 2025-03-01“…Compensation has been proposed as a mechanism to explain how individuals in very old age remain able to maintain normal cognitive functioning. …”
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17174
Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study
Published 2025-03-01“…Methods: A Mendelian randomization (MR) analysis was performed by extracting summary-level datasets for FH or FH concurrently with ischemic heart disease (IHD) and intestinal vascular diseases from the FinnGen study including 329,115, 316,290 and 350,505 individuals. The inverse-variance weighted (IVW) method and the weighted median method were applied to analyze the causal relationships between FH or FH concurrently with IHD and the risk of intestinal vascular diseases. …”
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17175
The necessity of gestational vitamin D supplementation depends on ambient temperature: concern for infant vitamin D status
Published 2025-01-01“…The daily mean temperature of Hefei was obtained from the China Meteorological Data Sharing Service System. Individual information on sociodemographic characteristics, perinatal health status, lifestyle, and birth outcomes was collected prospectively.ResultsThe best-fit relationship was observed in the regression model using a quadratic function to describe the association between the ambient temperature of the eighth gestational month (29–32 gestational weeks) and cord blood 25(OH)D concentrations (R2 = 0.358, p < 0.001). …”
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17176
Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis
Published 2025-01-01“…<b>Materials and Methods</b>: Metabolomic data were generated from normal, osteopenia, and osteoporosis groups with 320 participants recruited from the Nicheng community in Shanghai. We conducted individual edge network analysis (iENA) combined with a random forest to detect metabolomic biomarkers for the early warning of osteoporosis. …”
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17177
YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database
Published 2025-01-01“…The YHSeqY3000 panel was designed to capture the genetic diversity of Chinese paternal lineages from 3500 years ago, identifying 408 terminal lineages in 2097 individuals across 41 genetically and geographically distinct populations. …”
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17178
De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome
Published 2019-01-01“…Heteroplasmy levels of the m.3243A>G mutation in peripheral blood, saliva, and urine sediment of 31 individuals from 10 unrelated pedigrees were measured by pyrosequencing. …”
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17179
Bridging incremental to transformative hazard management strategies on the Tule River Indian Reservation
Published 2025-01-01“…Instead, transformative adaptation is necessary for meeting this need, although the pathways for how to create transformative as opposed to incremental change through individual action and social systems are challenging. …”
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17180
Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China
Published 2025-01-01“…Forty‐three symptoms were identified during SARS‐CoV‐2 infection (11 symptoms per individual). The common symptoms were fever, cough, headache, phlegm production, and fatigue (60.67%–83.29%). …”
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