Quality of Life Philosophy IV. The Brain and Consciousness by Søren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…If we come to understand brain and consciousness in order to solve this basic problem of our existence, we shall again be able to become a coherent part of the world, both as individuals and as a species. We share the vision that such an understanding of the problems of consciousness will make medical science holistic and will bring quality of life, health, and the ability to function to its patients.…”
Get full text

Impact of English proficiency on use of Glasgow Coma Scale in geriatric patients with traumatic brain injury by Veronica Layrisse-Landaeta, Gabriela R Dincheva, Shahenda Khedr, Andrew Geng, Michele Schombs, Kazi Maisha, Steven Y Chao, Chun-Cheng Chen

“…Moreover, GCS remained effective for predicting ICH in LEP individuals, highlighting its value with suitable translation resources.Level of evidence This is a Level III evidence restrospective comparative study.…”
Get full text

Emergency Endovascular Interventions on Descending Thoracic Aorta: A Single-Center Experience by Piotr Buczkowski, Mateusz Puslecki, Marcin Ligowski, Marek Dabrowski, Sebastian Stefaniak, Zuzanna Fryska, Jerzy Kulesza, Robert Juszkat, Marek Jemielity, Bartlomiej Perek

“…Early after the procedure, one individual developed transient paraparesis (1.3%). No other serious stent-graft-related adverse events were noted within the postdischarge follow-up period. …”
Get full text

Discondroplasia tibial de los pollos parrilleros by M. E. Dallorso

“…La discondroplasia tibial (TD) forma parte de un conjunto de alteraciones esqueléticas de las aves de corral producidas en forma intensiva, que entrañan disminución de la performance del lote, del rendimiento individual y del bienestar animal. Es un desorden del desarrollo, caracterizado por la permanencia de cartílago anormal en el extremo proximal de la tibia. …”
Get full text

Associations between subjective and objective measures of stress and load: an insight from 45-week prospective study in 189 elite athletes by Kristina Drole, Mojca Doupona, Kathrin Steffen, Kathrin Steffen, Aleš Jerin, Aleš Jerin, Armin Paravlic, Armin Paravlic

“…IntroductionThe aim of this study was to investigate the associations between subjective and objective measures of stress and load in elite male handball players at both the group and individual levels.MethodsIn this 45-week prospective cohort study, 189 elite male handball players weekly reported their perceived stress and load across training, competition, academic, and work domains. …”
Get full text

Parent-of-origin effects on nuclear chromatin organization and behavior in a Drosophila model for Williams–Beuren Syndrome by A. V. Medvedeva, E. V. Tokmatcheva, A. N. Kaminskaya, S. A. Vasileva, E. A. Nikitina, A. V. Zhuravlev, G. A. Zakharov, O. G. Zatsepina, E. V. Savvateeva-Popova

“…Prognosis of neuropsychiatric disorders in progeny requires consideration of individual (1) parent-of-origin effects (POEs) relying on (2) the nerve cell nuclear 3D chromatin architecture and (3) impact of parent-specific miRNAs. …”
Get full text

HISTORICAL-PHILOSOPHICAL-LEGAL RESEARCH OF THE PHENOMENON OF THE GENDER AS THE FACTOR OF THE SOCIAL STATUS OF THE UKRAINIAN WOMAN by H. F. Moskalyk, M. Y. Baranovska, M. O. Bulach

“…Modern problems of the state's socioeconomic development require a new look at the functional roles of men and women, as well as the understanding that the political, economic, cultural future of society depends on overcoming gender stereotypes that are deeply rooted in the social and individual consciousness and inhibit social progress, and also the development of democracy. …”
Get full text

Retrospective trend analysis of biocides in suspended particulate matter of major German rivers by Georg Dierkes, Susanne Schmidt, Christiane Meier, Korinna Ziegler, Jan Koschorreck, Arne Wick

“…For benthic organisms a toxicological risk from the individual azole fungicides and QACs seems to be low. …”
Get full text

“Loneliness is a sad disease”: oldest old adults’ empirical definition of loneliness and social isolation from a mixed-method study in Northern Italy by Sara Santini, Mauro Colombo, Antonio Guaita, Paolo Fabbietti, Georgia Casanova

“…Many studies apply the main definitions of loneliness and social isolation offered by the literature without considering how individual representations, socio-cultural context and the culture of care may influence their perception. …”
Get full text

Mining Potential Drug Targets and Constructing Diagnostic Models for Heart Failure Based on miRNA-mRNA Networks by Xiangming Fang, Rensheng Song, Jiaxing Wei, Qin Liao, Zhenhong Zeng

“…In addition, we found that 83 genes were upregulated and 92 genes were downregulated in HF patients vs. healthy individuals. Based on the inflammation-related score, hypoxia-related score, and energy metabolism-related score, we identified key miRNA-mRNA pairs and constructed an interaction network. …”
Get full text

Cost-effectiveness of targeted next-generation sequencing (tNGS) for detection of tuberculosis drug resistance in India, South Africa and Georgia: a modeling analysisResearch in co... by Suvesh Shrestha, Angelina Addae, Cecily Miller, Nazir Ismail, Alice Zwerling

“…Methods: To inform WHO guideline development group (GDG) on tNGS we developed a stochastic decision analysis model and assessed cost-effectiveness of tNGS for DST among rifampicin resistance individuals. We also assessed tNGS as initial test for TB drug resistance in bacteriologically confirmed TB. …”
Get full text

Using Health Information Resources for People With Cognitive Impairment (digiDEM Bayern): Registry-Based Cohort Study by Florian Weidinger, Nikolas Dietzel, Elmar Graessel, Hans-Ulrich Prokosch, Peter Kolominsky-Rabas

“…Understanding the relationship between dementia literacy, health information–seeking behavior, and the use of various information sources among individuals with cognitive impairment is of high importance in this context. …”
Get full text

Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience by Arber Aliu, Klodiana Durici, Ira Lazo, Altin Veshti

“…Material and Methods: Our research, based on a comprehensive analysis of data from the Society of Thoracic Surgeons in the USA's 10-year database, included individuals who underwent bioprosthetic SAVR following prior TAVR and/or SAVR. …”
Get full text

Comparison of Corneal Epitheliotrophic Factors of Undiluted Autologous Platelet-Rich Plasma and Autologous Serum Eye Drops for Dry Eye Disease by Passara Jongkhajornpong, Kaevalin Lekhanont, Sasivimol Rattanasiri, Prapaporn Pisitkun, Ammarin Thakkinstian

“…This could allow ophthalmologists to tailor treatments to individual patients by targeting growth factor supply based on their underlying pathophysiology. …”
Get full text

Evaluation of needs and supply of emergency care in Kinshasa, Democratic Republic of Congo: a cross-sectional household survey by Lee Wallis, Peter Hodkinson, Ken Diango, John Yangongo, Vera Sistenich, Eric Mafuta

“…Additional 303 respondents randomly selected in the households were interviewed regarding their personal reasons for not accessing emergency care.Primary outcome Availability and utilisation of emergency care services.Results In August 2021, 1217 households encompassing 6560 individuals were surveyed (response rate of 96.2%). …”
Get full text

Demographic Correlates of Infant Feeding Practices and Growth Performance in the First Year of Life by Leila M. Shinn, Christy C. Tangney, Caitlyn Busche, Christine M. Sharp, Mary C. Mullen

“…Continued research will allow for the development of an easy-to-use, succinct questionnaire that will allow healthcare providers to individualize feeding recommendations for caretakers of infants.…”
Get full text

Formation of the Educational Trajectory: Educational Motives and Choices in the Narratives of Students from Moscow Leading Universities by A. V. Noskova, D. V. Goloukhova, E. I. Kuzmina

“…Educational choices related to keeping or changing the educational trajectory are determined by the desire to avoid risks and having a high level of satisfaction with studies in the case of linear trajectories and the desire  to  gain  new  educational  experience,  obtaining  competencies  that  go  beyond  the  scope of the specialty being studied, as well as environmental factors of the university in the case of non-linear tracks.It is shown that a qualitative research strategy allows the researchers to look at reflected educational choices from the perspective of their semantic content, which is especially in demand due to the growing trend towards individualization of the educational process. It is concluded that empirical knowledge about the motives and methods of shaping the educational trajectories of the current generation of students is necessary for the development of an effective social and educational environment of a modern university, focused on a student-centered approach to learning.…”
Get full text

اعادة الهندسة الاداریة کمدخل لتمیز مؤسسات المعرفة by د. أمنیة خیر توفیق

“…Different types of knowledgeinstitutions need to re-engineer management , whether they suffer or not fromproblems of re-engineering in knowledge institutions : Service of reengineering ,reengineering process , reengineering ofmanagement systems , reengineering requires management improvementand development especially in the areas of organizational work , process outputs, system , and resources .A set of reengineering approaches that can be reliably applied toknowledge institutions is available from the results of the application of thereengineering approach to knowledge institutions : the transformation ofbusiness units from functional departments to operations teams , transformingjobs from simple tasks to complex work , the focus shifts on performancestandards , rewards and activities to results , Examples of obstacles that arepreventing the re-engineering approach to knowledge. institutions : the existenceof a culture of resistance to change, the lack of clarity of the knowledge        institution's vision , its organizational culture in the process of re-engineering, theuse of non-cadres to lead the process of administrative re-engineering, assigningadministrative re-engineering to retiring individuals , non-discrimination betweenadministrative re-engineering and other change programs, An example of therequirements for : The adequate awareness of the wishes of the beneficiaries ,an analysis of the institution's position and the design of the objectives of change, the belief of the senior management in the importance of change andencouragement of employees and understanding of the process of reengineeringadministrative management .Recommendations of the study : The need to adopt conscious leaders indifferent types of knowledge institutions , providing the necessary budget forapplying administrative reengineering in knowledge institutions , establishing aspecialized unit for reengineering of knowledge institutions , setting a plan for aspecific period of time of different types , especially the leaders in which newskills and knowledge on the reengineering management , monitoring theexperiences and management practices distinct in the field of reengineeringmanagement services facilities to document and benefit from them , increasingdependence needed to support administrative processes of reengineeringmethod of information technology .…”
Get full text

Economic evaluation of integrated services for non-communicable diseases and HIV: costs and client outcomes in rural Malawi by Luckson Dullie, Emily B Wroe, Elizabeth L Dunbar, Noel Kalanga, Lawrence Nazimera, Adarsh Shah, Bright Mailosi, Chiyembekezo Kachimanga, Ryan K McBain, Natalie Price, Mahlet Gizaw, Chantelle Boudreaux, Liberty Neba

“…This compared with $2 138 907 for standalone HIV services received by 6541 individuals, or $327 per capita. Over the 12-month period, 1970 new clients were enrolled in IC3, with a retention rate of 80%. …”
Get full text

Exploring manual therapy in the management of irritable bowel syndrome in adults: A scoping review by Natalia Płóciennik-Korycka, Sara Maria Pani, Bogumiła Bruc, Paolo Contu, Magdalena Wrzesińska

“…Objective: The objective of this review is to identify and map the available evidence on the effects of various manual therapy (MT) techniques on the biopsychosocial functioning, well-being, and QoL of individuals with irritable bowel syndrome (IBS). Methods: A comprehensive search was conducted in PubMed, Embase, and Scopus. …”
Get full text