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16601
Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion
Published 2019-01-01“…An earlier discovery that a hexanucleotide repeat expansion mutation in chromosome 9 open reading frame 72 (C9orf72) gene causes ALS and FTD established a special subtype of ALS and FTLD with TDP-43 pathology (C9FTD/ALS). Normal individuals carry 2–10 hexanucleotide GGGGCC repeats in the C9orf72 gene, while more than a few hundred repeats represent a risk for ALS and FTD. …”
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16602
Comparison of two skin protection regimes for the Prevention of Incontinence-associated Dermatitis in geriatric care (PID): a study protocol for an exploratory randomised controlle...
Published 2022-09-01“…Introduction The majority of aged long-term care receivers and patients in geriatric acute care are affected by some form of incontinence. These individuals are at risk of developing incontinence-associated dermatitis (IAD), a common type of irritant contact dermatitis caused by repeated and prolonged direct contact of the skin with urine and stool. …”
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16603
A survey on mental health among resident physicians: psychological resilience as a mediator
Published 2025-01-01“…The multiple-group analysis further revealed that individuals over 25 years exercise more PR to enhance LS (t = 2.703, p < 0.01), and those with normal weight were less affected by SD in terms of LS (t = − 2.322, p = 0.02). …”
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16604
The sporophytic type of fertility restoration in the A3 CMS-inducing cytoplasm of sorghum and its modification by plant water availability conditions
Published 2019-07-01“…For the first time, the transgenerational effect of water availability conditions of growing a fertility-restoring line on male fertility of the F2 generation was detected: a pollinator grown in a plot with additional irrigation produced more fertile and less sterile individuals compared to the same pollinator grown under a rainfall shelter (p < 0.01), and the segregation pattern changed from digenic to monogenic, indicating heritable inhibition of the expression of one of the fertility-restoring genes (kind of “grandfather effect”). …”
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16605
The assessment of the use of vehicles with different types of drive in car-sharing systems
Published 2024-12-01“… One of the main challenges of contemporary transport policy is to reduce the share of individual means of transport in the structure of transport, i.e., to reduce the number of private cars used as the primary means of transportation. …”
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16606
Analysis of emergency centre recidivism for interpersonal violence in a district-level hospital in Cape Town, South Africa
Published 2024-11-01“…Recidivism poses a measurable burden, and further research is needed to facilitate the identification of at-risk individuals, and specific secondary prevention strategies should be developed to prevent or reduce escalating patterns of injury associated with interpersonal violence. …”
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16607
Presence of Brucella spp. in Milk and Dairy Products: A Comprehensive Review and Its Perspectives
Published 2023-01-01“…To prevent and control brucellosis, essential steps include proper pasteurization of milk and dairy products, using the milk ring test (MRT) to detect Brucella in individual and bulk milk, immunization, education, and increasing public awareness of the disease. …”
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16608
The Relationship Between Self-Efficacy, Aerobic Fitness, and Traditional Risk Factors for Musculoskeletal Injuries in Military Training: A Prospective Cohort Study
Published 2025-01-01“… # Level of Evidence 2b Individual cohort study…”
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16609
Association between systemic immune-inflammation index and the risk of all-cause, cancer and non-cancer mortality in the general population: results from national health and nutrit...
Published 2025-01-01“…Results In fully adjusted model, the adjusted hazard ratio (aHR) and 95% confidence intervals (CIs) of individuals in Q4 were 1.24 (1.09, 1.41) for all-cause mortality and 1.41 (1.23, 1.63) for non-cancer mortality compared with Q1. …”
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16610
Global burden of musculoskeletal disorders and attributable factors in 204 countries and territories: a secondary analysis of the Global Burden of Disease 2019 study
Published 2022-06-01“…Objective To evaluate the global burden of musculoskeletal (MSK) disorders, as well as the five common conditions, and their relevant risk factors from 1990 to 2019.Design Data from the Global Burden of Disease Study 2019 were used in this study.Setting and participants Individuals of all ages and genders from 204 countries and territories in 21 regions.Main outcome measures The outcomes were the numbers and age-standardised rates (ASRs) of incident cases, deaths and disability-adjusted life-years (DALYs) of MSK disorders. …”
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16611
Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation
Published 2025-01-01“…Leveraging continuous feedback and real-time adjustments may overcome many of these barriers, and these next generation systems have the potential to stand at the forefront of precision medicine, offering new avenues for individualized and adaptive treatment.…”
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16612
Constructing a potential HLA haplo-homozygous induced pluripotent stem cell haplobank using data from an umbilical cord blood bank
Published 2025-02-01“…Conclusion The results suggested that at least some HLA-homozygous iPSC lines developed from Chinese individuals will not only be useful for covering the Chinese population but will also cover other Asian populations. …”
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16613
Wearable Smartphone-Based Multisensory Feedback System for Torso Posture Correction: Iterative Design and Within-Subjects Study
Published 2025-01-01“…We used this initial prototype in a feasibility study with individuals without hemiparesis (n=40, average age 28.4). …”
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16614
Association between phase angle and all-cause mortality in adults aged 18–49 years: NHANES 1999–2004
Published 2025-01-01“…Similarly, compared with those in the low PhA group, individuals in the high PhA group had a lower risk of all-cause mortality (HR = 0.67, 95% CI 0.46–0.98, P = 0.041). …”
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16615
To use and engage? Identifying distinct user types in interaction with a smartphone-based intervention
Published 2025-03-01“…Linear discriminant analyses, ANCOVAs, and MANOVAs were conducted to assess whether the clusters differed in intervention outcomes and individual characteristics. The analyses were replicated in data obtained in an RCT taking place in 2023 with an updated version of the app (n = 106). …”
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16616
Density of bacteria in Limnodrilus sp. culture fertilized by fermented chicken manure
Published 2007-01-01“…Highest density (11,948 individuals/m2) and biomass (14.65 g/ m2) of bacteria was obtained by 190 g of chicken manure fertilization. …”
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16617
Supplements to the <i>Proceedings on Applied Botany, Genetics and Breeding</i>: dedicated to the 115th anniversary of the journal
Published 2024-01-01“…Fundamental publications by Russian and foreign authors were noticed by domestic readers much faster when they appeared as supplements to a well-known journal that contained original articles, research results on individual crops, summaries and reviews in the field of applied botany, plant breeding and genetics.Academician Nikolay Vavilov, who headed the editorial committee, impelled all of his staff members, without exception, to publish their research findings first in the Proceedings, and only after that in other editions.Supplements 1–21 were published under the editorship of Robert Regel, and beginning from supplement 22 under the editorship of Nikolay Vavilov. …”
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16618
Association between triglyceride-glucose index and its composite obesity indexes and cardio-renal disease: analysis of the NHANES 2013-2018 cycle
Published 2025-01-01“…According to subgroup analyses, TyG and its composite obesity measurements were more strongly associated with CKD in younger individuals (≤ 50), males, and those with diabetes mellitus (P for interaction 0.05).ConclusionsThe TyG-WHtR and TyG-WC are associated with an increased risk of cardiac and renal disease, indicating enhanced diagnostic accuracy. …”
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16619
Compilation and functional classification of telomere length-associated genes in humans and other animal species
Published 2023-06-01“…An accelerated rate of telomere attrition can serve as a predictor of life expectancy and health status of an individual. Telomere length is a complex phenotypic trait that is determined by many factors, including the genetic ones. …”
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16620
Effect of oral potassium supplementation on urinary potassium excretion and its diagnostic value for primary aldosteronism
Published 2025-12-01“…The AUC for 24 h USR and 24 h UK before repletion in predicting PA were 0.788 and 0.652, respectively.Conclusions Urinary potassium does not increase proportionally with serum potassium levels or the oral potassium dose, showing individual variability. Post-supplementation urinary potassium has greater diagnostic value for distinguishing PA than pre-supplementation indicators.…”
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