Establishing of a risk prediction model for metabolic dysfunction-associated steatotic liver disease: a retrospective cohort study by Nan Li, Chenbing Liu, Zhangfan Lu, Wenjian Wu, Feng Zhang, Lihong Qiu, Chao Shen, Di Sheng, Zhong Liu

“…Identifying and preventing high-risk individuals for MASLD early is crucial. The purpose of our study is to investigate the factors related to the development of MASLD and develop a risk prediction model for its occurrence. …”
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Aberrant methylation of placental development genes in chorionic villi of spontaneous abortions with trisomy 16 by О. Yu. Vasilyeva, E. N. Tolmacheva, A. E. Dmitriev, Ya. A. Darkova, E. A. Sazhenova, T. V. Nikitina, I. N. Lebedev, S. A. Vasilyev

“…To obtain sequencing libraries, targeted amplification of individual gene regions using designed oligonucleot ide primers for bisulfite-converted DNA was used. …”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…In addition, pharmacological treatment must be performed. All individuals have statins implemented. In most cases, one drug isn't enough, so therapy containing ezetimib is common. …”
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Combat the growing prevalence of anaemia through underutilised iron-rich plant-based foods by Naman Kaur, Arthittaya Thuanthong, Simran Kaur, Aparna Agarwal, Manisha Sabharwal, Jatinder K. Sahu, Jayashree Arcot, Abhishek Dutt Tripathi, Pankaj Koirala, Nilesh Nirmal

“…Anaemia is a condition where a lowered level of red blood cells or haemoglobin is detected, which adversely affects an individual working capacity. World Health Organization and Food and Agriculture Organization have recommended four approaches to manage micronutrient deficiency – nutrition education, fortification, supplementation, and dietary diversity. …”
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Evaluating novel approaches for estimating awake and sleep blood pressure: design of the Better BP Study – a randomised, crossover trial by Paul Muntner, Ligong Chen, Daichi Shimbo, Joseph E Schwartz, Maria Cepeda, Demetria Hubbard, Suzanne Oparil, Byron C Jaeger, Shakia T Hardy, Julia Medina

“…Ambulatory BP monitoring (ABPM) can assess out-of-office BP but is not available in many US practices and some individuals find it uncomfortable. The aims of the Better BP Study are to (1) test if unattended office BP is closer to awake BP on ABPM compared with attended office BP, (2) assess if sleep BP assessed by home BP monitoring (HBPM) agrees with sleep BP from a full night of ABPM and (3) compare the strengths of associations of unattended versus attended office BP, unattended office BP versus awake BP on ABPM and sleep BP on HBPM versus ABPM with markers of end-organ damage.Methods and analysis We are recruiting 630 adults not taking antihypertensive medication in Birmingham, Alabama, and New York, New York. …”
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Persistence of gastrointestinal symptoms in irritable bowel syndrome and ulcerative colitis: study protocol for a three-arm randomised controlled trial (SOMA.GUT-RCT) by Ansgar W Lohse, Bernd Löwe, Kerstin Maehder, Yvonne Nestoriuc, Antonia Zapf, Eik Vettorazzi, Viola Andresen, Sina Hübener, Luisa Peters

“…Both active intervention groups will comprise three individual online consultation sessions and a booster session after 3 months. …”
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The autoimmune disease risk variant NCF1-His90 is associated with a reduced risk of tuberculosis in women by Xinjun Hu, Shasha Li, Renliang Huang, Ziwei Fu, Chenyu Ma, Zheng Cheng, Hongjun Hu, Qiaomiao Zhou, Frank Petersen, Xinhua Yu, Xinhua Yu, Junfeng Zheng

“…Additionally, healthy individuals with the NCF1 rs201802880 AA genotype had significantly lower circulating white blood cell (5.56 ± 1.78 vs 6.43 ± 1.59, p=0.003) and neutrophil (3.23 ± 1.20 vs 3.74 ± 1.23, p = 0.02) counts compared to those with the GG or GA genotypes, with this difference being more pronounced in women than in men.ConclusionThis study demonstrates that the autoimmune disease-causal NCF1 variant is associated with a protective effect against TB infection.…”
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Radiomic prediction for durable response to high‐dose methotrexate‐based chemotherapy in primary central nervous system lymphoma by Haoyi Li, Mingming Xiong, Ming Li, Caixia Sun, Dao Zheng, Leilei Yuan, Qian Chen, Song Lin, Zhenyu Liu, Xiaohui Ren

“…The training and validation cohorts comprised 76 and 29 individuals, respectively. Among them, 65 patients achieved DR. …”
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The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001–2018 by Juan Wu, Yingdong Han, Menghui Yao, He Zhao, Zhikai Li, Tiange Xie, Yun Zhang, Xuejun Zeng

“…Abstract Background Oxidative stress is a crucial pathophysiological mechanism in chronic diseases and mortality. While individual oxidative markers have been studied, the comprehensive impact of oxidative balance on mortality risks remains unclear, particularly among cancer survivors. …”
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Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedi... by Marie C. Hyslop, Diana E. Papaioannou, Robert Bolt, Matthew J. Wilson, Michael Bradburn, Janet Clarkson, Esther Herbert, Nicholas Ireland, Jennifer Kettle, Amanda Loban, Amy C. Norrington, Christopher Vernazza, Christopher Deery

“…The MAGIC trial highlighted variations within anaesthetic practice at individual, local, and regional levels. Lessons learned from the MAGIC trial identifies specific barriers to paediatric trial enrolment, offer solutions and discusses ongoing challenges. …”
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Poor sleep quality is associated with probable sarcopenia in community-dwelling older adults: Results from the longevity check-up (lookup) 8+ by Stefano Cacciatore, Riccardo Calvani, Jasmine Mancini, Francesca Ciciarello, Vincenzo Galluzzo, Matteo Tosato, Emanuele Marzetti, Francesco Landi

“…Bad sleep quality was reported by 28.3 % of participants and was more prevalent among women, physically inactive individuals, and those with dyslipidemia. Probable sarcopenia was more prevalent in participants with bad sleep quality (23.8 % vs. 18.7 %, p = 0.012). …”
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Hyperbaric oxygen therapy improves the effects of systemic steroid therapy for sudden sensorineural hearing loss by Yu-Ching Chen, Yu-Hsi Liu, Bor‐Hwang Kang, Cai-Sin Yao, Yao-Shen Chen, Wen-Chung Liu

“…Greater improvements were observed in patients with initial hearing loss of >50 dB and younger individuals. Conclusions: HBOT improves the effectiveness of SS treatment in SSNHL, with notable benefits for younger patients and those with an initial hearing loss of >50 dB. …”
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Development of the relationship between visual selective attention and auditory change detection by Yuanjun Kong, Xuye Yuan, Yiqing Hu, Bingkun Li, Dongwei Li, Jialiang Guo, Meirong Sun, Yan Song

“…It highlights that the close relationship between individual differences in the two processes emerges alongside their respective maturation and does not become evident until adulthood.…”
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Predicting Time in Range Without Hypoglycaemia Using a Risk Calculator for Intermittently Scanned CGM in Type 1 Diabetes by Fernando Sebastian‐Valles, Jose Alfonso Arranz Martin, Julia Martínez‐Alfonso, Jessica Jiménez‐Díaz, Iñigo Hernando Alday, Victor Navas‐Moreno, Teresa Armenta Joya, Maria del Mar delFandiño García, Gisela Liz Román Gómez, Jon Garai Hierro, Luis Eduardo Lander Lobariñas, Carmen González‐Ávila, Purificación deMartinez de Icaya, Vicente Martínez‐Vizcaíno, Miguel Antonio Sampedro‐Nuñez, Mónica Marazuela

“…Clinical data and net income from the census tract were collected for each individual. OGC was defined as time in range > 70%, with time below 70 mg/dL < 4%. …”
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Development of Speech and Communication in Polish Children with 22q11.2 Deletion Syndrome: A Cross-Sectional Study by Natalia Moćko, Marcin Rudzki, Zuzanna Miodońska, Julia Olesiak, Katarzyna Jochymczyk-Woźniak, Michał Kręcichwost

“…This paper presents a cross-sectional study on speech and communication of Polish children with 22q11DS. Methods: Individuals affected with 22q11DS may show difficulties in functioning, including speech and hearing. …”
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A scientometric visualization analysis of the gut microbiota and gestational diabetes mellitus by Zehao Su, Zehao Su, Lina Liu, Jian Zhang, Jian Zhang, Jingjing Guo, Jingjing Guo, Guan Wang, Xiaoxi Zeng, Xiaoxi Zeng

“…Key areas of focus include the interactions between the gut microbiota and individuals with GDM, as well as the formation and inheritance of the gut microbiota. …”
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Design, Content and Ecological Validity and Reliability of the Physical Activity and Sport Habits Questionnaire for Children Aged 8–12 Years in the Province of Gipuzkoa (Spain) by Aduna Badiola-Lekue, Irantzu Ibañez, Maite Fuentes, Javier Yanci, Oidui Usabiaga, Aitor Iturricastillo

“…<b>Methods:</b> The questionnaire design phase involved seven individuals from the university sector and sport managers from the Gipuzkoa Provincial Council. …”
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Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review by Marcin Komorowski, Michał Janiszewski, Aleksandra Pelczarska, Rafal Kaczorowski, Tomasz Forenc, Jaromir Hunia, Julia Górny, Jonasz Jurek, Alicja Kapciak

“…While caffeine’s ergogenic effects are well-established, its use should be personalized, considering individual responses and training status. Furthermore, caffeine's legal status and potential interactions with other substances, such as alcohol and medications, must be considered in competitive settings. …”
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Estimation of respiratory syncytial virus-associated hospital admissions in five European countries: a modelling studyResearch in context by Caroline Klint Johannesen, David Gideonse, Richard Osei-Yeboah, Toni Lehtonen, Ombeline Jollivet, Rachel A. Cohen, Arantxa Urchueguía-Fornes, María Herrero-Silvestre, Mónica López-Lacort, Rolf Kramer, Thea K. Fischer, Terho Heikkinen, Harish Nair, Harry Campbell, Michiel van Boven, Harish Nair, Hanna Nohynek, Anne Teirlinck, Louis Bont, Peter Openshaw, Andrew Pollard, Veena Kumar, Elizabeth Begier, Jim Janimak, Jenny Hendrix, Rolf Kramer, Alejandro Orrico Sánchez, Eva Molero

“…Summary: Background: Respiratory syncytial virus (RSV) can cause severe disease, notably among infants, older adults, and individuals with comorbidities. Non-systematic testing and differences in coding practices affect direct measures of the hospital disease burden. …”
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Volatile Organic Compounds as Biomarkers of Gastrointestinal Diseases and Nutritional Status by Mariangela Rondanelli, Federica Perdoni, Vittoria Infantino, Milena Anna Faliva, Gabriella Peroni, Giancarlo Iannello, Mara Nichetti, Tariq A. Alalwan, Simone Perna, Clementina Cocuzza

“…VOC analysis allowed to highlight differences in behavior, lifestyle, and metabolism of individuals. Analytical methods are continuously developed to allow for better detection and quantification of metabolites, thus enabling the detection of a broader spectrum of pathophysiology and disease biomarkers.…”
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