Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies by Niloofar Javid, Ali Asadipour, Ehsan Salarkia, Mohammad Amin Langarizadeh, Fatemeh Sharifi, Mohammad Mahdavi, Bagher Amirheidari, Aida Iraji, Hojjat Rezaiezadeh, Gholamreza Hassanpour, Yaghoub Pourshojaei

“…Abstract Leishmaniasis is a parasitic disease caused by protozoan organisms belonging to the Leishmania genus, affecting many individuals worldwide, with the burden surpassing one million cases. …”
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Immune Thrombocytopenia in a worker exposed to toluene: a case report by Eric Slawka, Margarida Lourenço Castelló, Gabriel Machado Romão da Silva, Angelica dos Santos Vianna

“…Introduction: Immune thrombocytopenia (ITP) is the most common cause of isolated thrombocytopenia in healthy individuals and can be classified as either primary or secondary. …”
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Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation by Hyeseon Lee, Young-Mi Park, Yu-Mee We, Duck Jong Han, Jung-Woo Seo, Haena Moon, Yu-Ho Lee, Yang-Gyun Kim, Ju-Young Moon, Sang-Ho Lee, Jong-Keuk Lee

“…We found that at least 24% of the highly polymorphic SNPs used to identify individuals could also identify donor cfDNA in transplant patient samples. …”
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Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess by Sandhya Khunger, Abhishek Mewara, Upninder Kaur, Ajay Duseja, Pallab Ray, Naveen Kalra, Navneet Sharma, Rakesh Sehgal

“…Blood samples from 100 ALA and 41 healthy individuals were collected. mRNA expression of TLR 1 to 9 genes was measured using reverse transcriptase polymerase chain reaction (RT-PCR). …”
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Prevalence and sociodemographic characteristics of functional impairment in community-dwelling older adults in China: a cross-sectional study by Yun Li, Li Zhang, Zhe Tang, Lina Ma, Pan Liu, Xiaxia Li, Wenhua Yu, Yaxin Zhang

“…The prevalence was higher among women and individuals in rural areas and increased with age. Illiteracy, no spouse, living alone, poor self-reported health, low income, limited meat intake, less exercise, chronic diseases and geriatric syndromes were associated with functional impairment. …”
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Salivary Levels of Interleukin-17 in Iranian Patients With Systemic Sclerosis by Ali Tadayon, Javad Moayedi, Mohamad Ali Nazarinia, Mahyar Malekzadeh, Sara Kazemi, Maryam Mardani

“…In this cross-sectional study, unstimulated saliva samples were collected from patients with SSc (n=80) and age- and sex- matched healthy individuals (n=80). The salivary levels of IL-17 in all samples were measured using a commercially available enzyme–linked immunosorbent assay (ELISA) kit. …”
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Promiscuous Chemokine Antagonist (BKT130) Suppresses Laser-Induced Choroidal Neovascularization by Inhibition of Monocyte Recruitment by Shira Hagbi-Levi, Michal Abraham, Liran Tiosano, Batya Rinsky, Michelle Grunin, Orly Eizenberg, Amnon Peled, Itay Chowers

“…Age-related macular degeneration (AMD), the most common cause of blindness in the developed world, usually affects individuals older than 60 years of age. The majority of visual loss in this disease is attributable to the development of choroidal neovascularization (CNV). …”
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A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer’s Disease by Jorge I. Vélez, Dora Rivera, Claudio A. Mastronardi, Hardip R. Patel, Carlos Tobón, Andrés Villegas, Yeping Cai, Simon Easteal, Francisco Lopera, Mauricio Arcos-Burgos

“…Here we report the results of a targeted analysis of functional exonic variants in those AOO modifier genes in sixty individuals with PSEN1 E280A AD who were whole-exome genotyped for ~250,000 variants. …”
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Effectiveness of Acupuncture for Lateral Epicondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yumei Zhou, Yuebao Guo, Rui Zhou, Ping Wu, Fanrong Liang, Zhuoxin Yang

“…Ten RCTs involving 796 individuals were included in this meta-analysis. Three studies reported randomized methods with a specific description. …”
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Analysis of Health Impacts from Future Air Quality Changes Considering the Aging Population in Korea by Jinseok Kim, Youjung Jang, Hyejung Hu, Younha Kim, Bomi Kim, Seung Jick Yoo, Jae-Bum Lee, Seung-Hee Eun, Sung-Chul Hong, Hyungah Jin, Jung-Hun Woo

“…This finding suggests that, although PM_2.5 concentrations are expected to decline, the increasing proportion of elderly individuals will exacerbate health risks. Therefore, accounting for aging population trends is essential when studying the health impacts of future air quality changes.…”
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Sociodemographic and clinical determinants of suicidal ideation: an analysis in a Peruvian consultation-liaison psychiatry unit by Jeff Huarcaya-Victoria, José Salvador-Carillo, Michaell Cabrejos-Espinoza, Mercedes Ponce-Pantigoso, Kelly Broncano-Rivera, Andrea Loarte-Cabrera

“…Abstract Background Suicidal ideation (SI) poses a significant global health concern, particularly among hospitalized individuals, with gaps in understanding its contributing factors in low and middle-income countries like Peru. …”
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The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank by Divya Bhagtani, Birdem Amoutzopoulos, Toni Steer, David Collins, Suzanna Abraham, Bridget A Holmes, Baldeesh K Rai, Rajendra Pradeepa, Sara Mahmood, Abu Ahmed Shamim, Poorvee Mathur, Lathika Athauda, Laksara De Silva, Khadija I Khawaja, Vinitaa Jha, Anuradhani Kasturiratne, Prasad Katulanda, Malay K Mridha, Ranjit M Anjana, John C Chambers, Polly Page, Nita G Forouhi

“…Median energy intake was higher in younger individuals compared to older, and in males compared to females. …”
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Development of a comprehensive sustainability index for extractive and mining companies: Integrating the Sustainable Development Goals by Marta Fernández-Hernández, Pedro Mora, Marcelo F. Ortega, Juan Pous Cabello

“…The methodology leverages a metric index scoring system to evaluate and enhance their sustainability performance.The methodology involves scoring a series of parameters associated with each SDG, resulting in individual indices that are rescaled for comparability. …”
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State of the Art Compendium: Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease by Denis E O’Donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…Therapy should be escalated on an individual basis in accordance with the increasing severity of symptoms and disability. …”
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Valorization of rice stubble through biodegradation using hydrolytic enzyme-producing Olivibacter oleidegradans CMB10 and Agrobacterium pusense SFMB9 by Milind Gajbhiye, Sushmita Patil, Sagar Awate, Supriya Kokare, Siddharth Terdale, Manish Kumar Dubey

“…The highest stubble degradation (86.3 %) was recorded in the case of co-inoculated treatment on 45th day as compared with individual microbial treatments (P < 0.05). However, there was a significant difference between all the bacterial treatments and uninoculated control on 15, 30 and 45th day of incubation. …”
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High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota by Yu Xia, Yu Xia, Lulu Wang, Yanyan Qiu, Weihong Ge, Weihong Ge, Weihong Ge

“…Our previous study identified significantly lower levels of fecal thiamine in individuals with obesity; however, its potential and mechanisms for alleviating obesity induced by a high-fat and high-fructose diet (HFFD) remain unclear. …”
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Diet-microbiome covariation across three giraffe species in a close-contact zone by Elin Videvall, Brian A. Gill, Michael B. Brown, Hannah K. Hoff, Bethan L. Littleford-Colquhoun, Peter Lokeny, Paul M. Musili, Tyler R. Kartzinel

“…However, contrary to expectations, we found very little evidence for links between the composition of individual diets and their corresponding microbiomes. …”
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No closure of the linea alba cervicalis reduces complications in endoscopic thyroidectomy by Tiantian Jiang, Yuanhao Su, Yongke Wu, Cheng Li, Tingkai Sun, Yunhao Li, Yuanyuan Ji, Zhidong Wang

“…A retrospective analysis was performed. 142 patients were enrolled and divided into two groups, including 71 individuals in the improvement group (no suture of the linea alba cervicalis) and 71 in the conventional group (suture the linea alba cervicalis). …”
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Diverse pathways to decarbonization: cluster-specific impacts of energy sources on CO2 emissions in the European Union by Jana Chovancová, Igor Petruška, Ugur Korkut Pata, Peter Adamišin

“…Coefficients of determination R2 for individual clusters ranges from 0.9818 to 0.9940, indicating the high reliability of the models. …”
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Gastrointestinal Bleeding due to Pancreatic Disease-Related Portal Hypertension by Kexin Zheng, Xiaozhong Guo, Ji Feng, Zhaohui Bai, Xiaodong Shao, Fangfang Yi, Yongguo Zhang, Rui Zhang, Han Liu, Fernando Gomes Romeiro, Xingshun Qi

“…Clinicians should individualize the treatment strategy of LSPH according to the patients’ clinical conditions and nature of pancreatic diseases.…”
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