Proactive and Integrated Management and Empowerment in Parkinson’s Disease: Designing a New Model of Care by Emma Tenison, Agnes Smink, Sabi Redwood, Sirwan Darweesh, Hazel Cottle, Angelika van Halteren, Pieter van den Haak, Ruth Hamlin, Jan Ypinga, Bastiaan R. Bloem, Yoav Ben-Shlomo, Marten Munneke, Emily Henderson

“…It is widely recognised that the current models of care for people with Parkinson’s disease or a form of atypical parkinsonism lack continuity, are reactive to problems rather than proactive, and do not adequately support individuals to self-manage. Integrated models of care have been developed for other chronic conditions, with a range of positive effects. …”
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Advanced sleep disorder detection using multi-layered ensemble learning and advanced data balancing techniques by Muhammad Mostafa Monowar, S. M. Nuruzzaman Nobel, Maharin Afroj, Md Abdul Hamid, Md Zia Uddin, Md Mohsin Kabir, M. F. Mridha

“…Moreover, an eight-fold cross-validation yielded an impressive 99.5% accuracy, indicating the reliability of the model in handling unbalanced data and ensuring precise detection of sleep disorders. Compared to individual models, the proposed ensemble method significantly outperformed traditional models. …”
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The moderating role of social support on the impact of adverse childhood experiences on life satisfaction and mental health in adulthood by Muath Aldomini, Jerry W. Lee, Anna Nelson, Rhonda Spencer Hwang, Khulud K. Alharbi, Tassnym H. Sinky, Baraa S. Quronfulah, Wahaj A. Khan, Mohamed O. Elamin, Mohamed O. Nour

“…When interacting with individuals who have had ACEs, health providers need to be mindful of the possible effects of both PSS and NSS. …”
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Effects of Four-Week Intake of Blackthorn Flower Extract on Mice Tissue Antioxidant Status and Phenolic Content by Vedran Balta, Domagoj Đikić, Irena Crnić, Dyna Odeh, Nada Orsolic, Ivana Kmetič, Teuta Murati, Verica Dragović Uzelac, Irena Landeka Jurčević

“…Phenolic profiles were different in individual tissues. The most prominent increases compared to the control were determined for contents of 3- O -feruloylquinic acid, 4- O-p -coumaroylqiunic acid, kaempferol pentoside, and quercetin rhamnoside in the intestine; for ferulic acid and quercetin 3- O -rutinoside in the liver; and for quercetin 3- O -rutinoside, ferulic acid, and 4- O-p -coumaroylquinic acid in the kidneys. …”
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Iron deficiency anaemia and its associated risk factors among lactating mothers in Ghana by Mensah K, Abbam G, Gadzeto FF, Marfo L, Daud S, Kuntah S, Bani SB, Dzamesi HK, Apodola FA, Badu A, Chukwurah FE

“…Iron deficiency, with or without anaemia, reduces the working capacity of individuals and the entire population. The aim of the study was to establish the prevalence of anaemia; iron deficiency anaemia using serum ferritin levels and factors associated with iron deficiency anaemia among lactating mothers in the district. …”
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The Effects of Active Galactic Nuclei Feedback on the Lyα Forest Flux Power Spectrum by Megan Taylor Tillman, Blakesley Burkhart, Stephanie Tonnesen, Simeon Bird, Greg L. Bryan

“…AGN feedback can also alter the thermal evolution of the IGM and thermally broaden individual Ly α absorbers. For the Simba model, these effects become observable at z  ≲ 1.0. …”
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A Huge Innovation in Diagnosis of Obstructive Sleep Apnea Syndrome: With an Artificial Intelligence-Based Algorithm, Obstructive Sleep Apnea Syndrome Can Now Be Diagnosed With Pulm... by Seval Bulut Eris, Mehmet Recep Bozkurt, Omer Eris, Cahit Bilgin

“…The diagnostic process is difficult, costly, and time-consuming. Many individuals with OSAS do not apply for a diagnosis or are unaware of their disease. …”
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Prevalence and factors associated with burnout syndrome in resident physicians: A cross-sectional study in Italy by Luca DI GIAMPAOLO, Andrea ROSSETTI, Teresa GALANTI, Simone DE SIO, Luca COPPETA, Hector NIETO, Hiroo WADA, Niu QUIAO, Younes RAMI, Hicham KHABBACHE, Driss AIT ALI, Amelia RIZZO, Kavita BATRA, Murat YILDIRIM, Mahmood BAHRAMIZADEH, Francesco CHIRICO

“…These findings support existing studies that burnout is strongly associated with work-related factors over individual-level demographic factors. Furthermore, residents who maintain a good work-life balance report lower burnout levels compared to those who struggle to achieve this balance.…”
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Anthocyanins as functional food components by R. S. Yudina, E. I. Gordeeva, O. Yu. Shoeva, M. A. Tikhonova, E. K. Khlestkina

“…Other data ascribe the positive effect on human health not to individual anthocyanins, but to the whole complex of polyphenolic compounds consumed. …”
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Novel functional eQTL-SNPs associated with susceptibility to occupational pulmonary fibrosis: A multi-stage study by Rui Zhao, Xiaobo Tao, Wendi Zhang, Siqi Li, Shenxuan Zhou, Anhui Ning, Zhenyu Li, Minjie Chu, Wei Wang, Junhong Jiang

“…The joint analysis indicated the risk of developing silicosis was higher in individuals who carried more unfavorable alleles of rs1620530 and rs2070063. …”
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Occupational Exposure to Low Concentrations of Lead Dust and Oxidative Stress in Mine Workers by Fateme Kooshki, Masoud Neghab, Fatemeh Rahimian, Fereshteh Aliasghari, Esmaeel Soleimani

“…This study aims to assess the relationship between OS parameters and exposure to low concentrations of lead dust in mine workers.Methods: This cross-sectional study evaluated 73 lead-exposed workers and 70 age- and sex-matched non-exposed individuals. Demographic data and occupational and medical history were collected through questionnaires. …”
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Cardiovascular and Autonomic Responses after a Single Bout of Resistance Exercise in Men with Untreated Stage 2 Hypertension by Marcus Vinicius Machado, Thais de Paola Chequer Barbosa, Thais Camasmine Chrispino, Fabricia Junqueira das Neves, Gabriel Dias Rodrigues, Pedro Paulo da Silva Soares, Antonio Claudio Lucas da Nóbrega

“…We conclude that a single bout of RE induced an increase in vascular reactivity and reduced the pressure load by attenuating AUC of DBP in hypertensive individuals who had never been treated with antihypertensive medications.…”
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Association between higher mortgage payment-to-income ratio and greater psychological distress among high-income homeowners in Japan: A cross-sectional study by Kazuya Ogawa, Keiichi Shimatani, Ryotaro Iwayama, Norimichi Suzuki

“…Results: For both overall respondents (PR = 1.22, 95 % CI 1.11–1.35) and the high-income group (PR = 1.23, 95 % CI 1.09–1.39), individuals with mortgage payment ratios ≥30 % were more likely to report psychological distress compared with those <30 %. …”
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Associations between intake of different types of vegetables and metabolic dysfunction-associated fatty liver disease: a population-based study by Chong Liu, Yubo Liu, Jie Liu, Jia Liu, Ting Lu, Jingjia Yu, Guogang Zhang, Kai Xu

“…The objective of this study is to investigate the impact of different types of vegetables on MAFLD, aiming to provide a scientific basis for developing more appropriate dietary recommendations for individuals at high risk of MAFLD. Methods We investigated the associations between various types of vegetable consumption and the risk of MAFLD, utilizing data sourced from the National Health and Nutrition Examination Survey (NHANES) 2017–2018 cycle. …”
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Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain by Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg

“…In two neural tissues isolated from paired postmortem samples (same individuals), we found a significant increase in the frequency of deletions in both brain areas, namely, the frontal cortex and cerebellum. …”
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Correlation Between Shoulder Pain Severity, Acromion Morphology, and Acromiohumeral Distance Using MRI: A Study at Haji Adam Malik Hospital Medan in 2022 by Husnul Fuad Albar, Geon Rendy, Iman Dwi Nanto

“…Specific acromion morphologies may predispose individuals to rotator cuff tears. Furthermore, studies have found a correlation between supraspinatus tendon tears and acromiohumeral distance. …”
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A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study by Abdulhameed Alkhalaf, Qasem Aljabr, Khalid Al Mulla, Duaa Almubarak, Abdul Sattar Khan, Zainab Y. Al Jaziri, Ibrahim Albahrani

“…High-density lipoprotein (HDL) was protective, reducing ASCVD risk by 3%. Among high-risk individuals, 29.7% used aspirin, and 58.3% used statins. …”
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Association between prognostic nutritional index and all-cause mortality and cardiovascular disease mortality in American adults with non-alcoholic fatty liver disease by Yuqing Lei, Shaohong Tao, Yubo Yang, Fang Xie, Weining Xie

“…Time-dependent ROC analysis highlighted the strong predictive performance of PNI across various time points.ConclusionPNI played a significant role as an effective predictor of prognosis in individuals diagnosed with NAFLD.…”
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Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…Through the integrated omics analysis, we could understand the mechanism of inter-individual variability in drug exposure and in adverse response. …”
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Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer by Liping Luo, Juan Ji, Juan Dong, Maotao He, Wenjun Jiang, Yang Liu, Weidong Wang

“…They originate from T cells interacting with B cells, and their levels are abnormally elevated in individuals with immune disorders, as well as in some cancer patients. …”
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