Discrimination and calibration performances of non-laboratory-based and laboratory-based cardiovascular risk predictions: a systematic review by Yihun Mulugeta Alemu, Sisay Mulugeta Alemu, Dan Chateau, Nasser Bagheri, Kinley Wangdi

“…However, in most reviewed studies, the HRs for these additional predictors were substantial, significantly altering predicted risk, particularly for individuals with higher or lower levels of these predictors compared with the average.…”
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Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population by M. A. Charles-Davies, A. A. Fasanmade, J. A. Olaniyi, O. E. Oyewole, M. O. Owolabi, J. R. Adebusuyi, O. Hassan, M. T. Ajobo, M. O. Ebesunun, K. Adigun, K. S. Akinlade, U. A. Fabian, O. O. Popoola, S. K. Rahamon, W. Okunbolade, M. A. Ogunlakin, O. G. Arinola, E. O Agbedana

“…Metabolic alterations and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable metabolic factors may be necessary to reduce MS and high BP.…”
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Impact of the Ottawa model on opiate screening and smoking cessation in methadone-treated patients with opioid use disorder: A retrospective cohort analysis by Shu-Wua Lee, Po-Chung Yu, Ting-Ting Yen, Chiann-Yi Hsu, Li-Jou Lai, I-Chun Chen, Ting-Gang Chang

“…Introduction Approximately 60 million individuals worldwide used opioids in 2021, constituting 1.2% of the global adult population. …”
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RadBone: bone toxicity following pelvic radiotherapy – a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecologica... by Janelle Yorke, Sarah O’Connell, Sally Taylor, Karen Johnson, Robert G Bristow, Martin Eden, Kate Haslett, John Moore, Rohit Kochhar, Victoria Chatzimavridou Grigoriadou, Lisa H Barraclough, Ivona Baricevic-Jones, Zoe Merchant, Thomas Westwood, Anthony David Whetton, Claire E Higham

“…The RadBone randomised controlled trial (RCT) aims to determine the feasibility and acceptability of a musculoskeletal health package (MHP) intervention in women undergoing pelvic radiotherapy for gynaecological malignancies and to preliminary explore clinical effectiveness of the intervention.Methods and analysis The RadBone RCT will evaluate the addition to standard care of an MHP consisting of a physical assessment of the musculoskeletal health, a 3-month prehabilitation personalised exercise package, as well as an evaluation of the fracture risk and if required the prescription of appropriate bone treatment including calcium, vitamin D and—for high-risk individuals—bisphosphonates. Forty participants will be randomised in each group (MHP or observation) and will be followed for 18 months. …”
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Pigmented pathological type and depth of follicular extension as predictors of treatment failure in 5-aminolevulinic acid photodynamic therapy for actinic keratosis: A retrospectiv... by Qinyuan Zhu, Huyan Chen, Jing Luan, Qiong Huang, Lianjun Chen, Wenyu Wu, Shujun Chen

“…These findings highlight the importance of these specific features when assessing prognosis and tailoring treatment strategies for individual AK patients.…”
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Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients by Ehab H. Mattar, Hussein A. Almehdar, Abdullah A. AlJaddawi, Isam ElDin M. Abu Zeid, Elrashdy M. Redwan

“…Total defensin concentrations in HCV-infected patients were significantly higher (2- to 105-fold) compared to healthy individuals. The concentrations of α-defensins were also significantly elevated in the HCV-infected patients (31–1398 ng/50 μL). …”
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Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia by Aleksandra Savić, Ana Alimpić Aradski, Jelena Živković, Katarina Šavikin, Snežana Jarić, Petar D. Marin, Sonja Duletić-Laušević

“…The highest contents of total flavonoids and individual compounds, such as arbutin and chlorogenic acid, as well as the strongest antioxidant and TYR inhibitory activities were reported for the ‘Takiša’ peel extract. …”
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Association of fatty acid desaturase 2 gene polymorphism (rs28456) with susceptibility to bipolar disorder in the Turkish population: A case-control study by Pirim Dilek, Gümüş Ceren, Boztepe Esra, Akdağ Emine Merve, Şirin Hande

“…FADS2 variations may contribute to the individual risk of developing bipolar disorder (BD). …”
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Clinician’s perceptions and experiences with tobacco treatment in people who use cannabis: a qualitative study by Cristina Martínez, Marga Pla, Ariadna Feliu, Marta Enríquez, Judith Saura, Carmen Cabezas, Joan Colom, Josep M. Suelves, Sílvia Mondon, Pablo Barrio, Magalí Andreu, Antònia Raich, Jordi Bernabeu, Xavier Roca, Maite Narváez, Esteve Fernández, Group of clinicians of the ACT_ATAC study

“…Results Five main themes and 17 subthemes emerged: Individual characteristics, Clinician characteristics, Models of intervention, Organizational healthcare models, and Health policies. …”
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The moderating effect of psychological capital on the relationship between nurses’ perceived workplace bullying and emotional exhaustion: a cross-sectional study by Xiao Peng, Jing Ma, Ying Chen, Ying Han, Hong Zhou, Aiping Gong, Fang Peng, Xinzhang Sun, Xingfen Wang, Xunya Xiong, Li Li, Mengting Huang, Qingsong Zeng

“…PsyCap mitigates this impact, but this effect is limited in organizations with high WPB. it is recommended that nursing managers mitigate the detrimental impact of WPB on nurses’ emotional well-being by both strengthening nurses’ individual PsyCap and implementing comprehensive strategies to reduce WPB behaviors.…”
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Assessment of Minerals, Bioactive Compounds, and Antioxidant Activity of Ten Moroccan Pomegranate Cultivars by Sarah Loukhmas, Ebrahim Kerak, Meriem Outaki, Majdouline Belaqziz, Hasnaâ Harrak

“…Mineral composition, organic acids, total polyphenols, anthocyanins content, individual phenolic compounds, and antioxidant activity were determined in pomegranate juices. …”
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The effect of sowing dates on the yield of soybean (<i>Glycine max</i> (L.) Merr.) accessions differing in maturity schedules under the climate conditions of Irkutsk Province by N. B. Katysheva, A. V. Pomortsev, N. V. Dorofeev, S. Yu. Zorina, L. G. Sokolova, A. S. Zhuravkova, Yu. S. Bukin, A. I. Katyshev

“…The case study of two soybean genotypes differing in maturation schedules revealed the need for individual selection of sowing dates. It was shown that the early-ripening soybean genotype imposed less stringent requirements on the choice of sowing dates.…”
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Chinese nurses’ perspectives on child-friendly healthcare practice assessment: a qualitative study by Wei Xiao Huang, Mei Chan Chong, Li Yoong Tang, Xiao Xia Liu, Mei Fang, Yun Yun Shen, Xiao Li Guo

“…Method This descriptive qualitative study employed purposive and snowball sampling methods to recruit 14 pediatric nurses from six hospitals in Zhejiang province, Southeast China. Individual semi-structured interviews were conducted face-to-face between January and June 2024. …”
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The Impact of Time-Restricted Eating and Intermittent Fasting on Glycemia, Body Weight, and Overall Well-Being in Patients with Type 2 Diabetes – A Review of Studies by Szymon Przemysław Stolarczyk, Kuba Borys Romańczuk, Zofia Martyna Wójcik, Bartosz Omasta, Daria Rybak, Magdalena Agata Czerska, Paulina Dorota Pietrukaniec, Olga Krupa, Katarzyna Kamińska-Omasta, Kinga Furtak

“…  Introduction Intermittent fasting is becoming increasingly popular, particularly among individuals with obesity. One variation of this approach is time-restricted eating (TRE), which involves consuming meals only during a specific time window, typically lasting between eight to twelve hours each day.  …”
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A prediction model of liver fat fraction and presence of non-alcoholic fatty liver disease (NAFLD) among patients with overweight or obesity by Jie Chen, Jiang Yue, Jingjing Fu, Shengyun He, Qianjing Liu, Minglan Yang, Wang Zhang, Hua Xu, Qing Lu, Jing Ma

“…In order to comprehensively assess hepatic lipid deposition in individuals with overweight or obesity, we have devised a pioneering prognostic formula that capitalizes on clinical parameters. …”
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Genome sequences of four Ixodes species expands understanding of tick evolution by Alexandra Cerqueira de Araujo, Benjamin Noel, Anthony Bretaudeau, Karine Labadie, Matéo Boudet, Nachida Tadrent, Benjamin Istace, Salima Kritli, Corinne Cruaud, Robert Olaso, Jean-François Deleuze, Maarten J. Voordouw, Caroline Hervet, Olivier Plantard, Aya Zamoto-Niikura, Thomas Chertemps, Martine Maïbèche, Frédérique Hilliou, Gaëlle Le Goff, Jindřich Chmelař, Vilém Mazák, Mohamed Amine Jmel, Michalis Kotsyfakis, José María Medina, Michael Hackenberg, Ladislav Šimo, Fotini A. Koutroumpa, Patrick Wincker, Petr Kopáček, Jan Perner, Jean-Marc Aury, Claude Rispe

“…Results Here, we present the genome sequences of four tick species, derived from a single female individual, with a particular focus on the European species Ixodes ricinus, achieving a chromosome-level assembly. …”
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Saprotrophic Wood Decay Ability and Plant Cell Wall Degrading Enzyme System of the White Rot Fungus <i>Crucibulum laeve</i>: Secretome, Metabolome and Genome Investigations by Alexander V. Shabaev, Olga S. Savinova, Konstantin V. Moiseenko, Olga A. Glazunova, Tatyana V. Fedorova

“…The basidiomycete <i>Crucibulum laeve</i> strain LE-BIN1700 (Agaricales, <i>Nidulariaceae</i>) is able to grow on agar media supplemented with individual components of lignocellulose such as lignin, cellulose, xylan, xyloglucan, arabinoxylan, starch and pectin, and also to effectively destroy and digest birch, alder and pine sawdust. …”
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Genome‐wide association study of tuberculosis in the western Chinese Han and Tibetan population by Hao Bai, Mengyuan Song, Shikun Lei, Lin Jiao, Xuejiao Hu, Tao Wu, Jiajia Song, Tangyuheng Liu, Wu Peng, Zhenzhen Zhao, Zirui Meng, Binwu Ying

“…In the discovery stage, 3116 (1532 TB patients and 1584 healthy controls) and 439 (211 TB patients and 228 healthy controls) individuals were genome‐wide genotyped from a western Chinese Han and Tibetan population, respectively. …”
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Application of the principle of retroactivity in ukrainian legislation for commitment of applicable offenses against property by Lototskyi M., Dzundza L.

“…The application of the principle of retroactivity of law allows individuals and legal entities to be confident in the legal assessment of their actions not only when they are committed, but also in the future. …”
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Inflammatory biomarkers profiles and cognition among older adults by Aline Thomas, Jing Guo, Dolly Reyes-Dumeyer, Danurys Sanchez, Nikolaos Scarmeas, Jennifer J. Manly, Adam M. Brickman, Rafael A. Lantigua, Richard Mayeux, Yian Gu

“…However, inflammatory markers are regulated and influenced by each other, and it is therefore important to consider a more comprehensive panel of markers to better capture diverse immune pathways and characterize the overall inflammatory profile of individuals. We explored 23 circulating inflammatory biomarkers using data from 1,743 participants without dementia (≥ 65 years-old) from the community-based, multiethnic Washington Heights Inwood Columbia Aging Project. …”
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