Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes by Luqi Qin, Bei Fan, Yixia Zhou, Jiahuan Zheng, Rao Diao, Fengzhong Wang, Jiameng Liu

“…Studies have shown significant differences in the gut microbiota between healthy individuals and T2DM patients, suggesting that gut microorganisms may play a key role in the onset and progression of T2DM. …”
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Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT by Bibo Yuan, Citlalli Osorio-Yáñez, Junkai Fang, Lei Zhao, Ander Wilson, Marco Sanchez-Guerra, Hongbin Liu, Peng-Hui Li, Liqiong Guo

“…If these findings are confirmed in other cohorts, thyroid examinations should be conducted for individuals exposed to vibration in the workplace.…”
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Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling by Oleksandr Dudin, Oleksandr Dudin, Ozar Mintser, Vitalii Gurianov, Nazarii Kobyliak, Nazarii Kobyliak, Denys Kozakov, Sofiia Livshun, Oksana Sulaieva, Oksana Sulaieva

“…The sensitivity and specificity of the model were 86.1% and 72.7%, respectively.ConclusionThe developed model, which relies on routine histological features, allows the identification of individuals at high risk of CM recurrence to tailor their further management.…”
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IL18 Polymorphism and Periodontitis Susceptibility, Regardless of IL12B, MMP9, and Smoking Habits by Patrícia Yumeko Tsuneto, Victor Hugo de Souza, Josiane Bazzo de Alencar, Joana Maira Valentini Zacarias, Cléverson O. Silva, Jeane Eliete Laguila Visentainer, Ana Maria Sell

“…This case-control study involved 381 individuals matched by gender and age. Genotyping of IL18 (rs187238 and rs1946518) and IL12B (rs3212227) was performed by PCR-SSP and PCR-RFLP was used for MMP9 (rs3918242). …”
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Monthly or Weekly Supplementation with Cholecalciferol 20,000 IU in People Living with HIV: Results from a Nested Cohort Study by Sebastian Noe, Christine I. Moeckel, Christiane Schwerdtfeger, Celia Oldenbuettel, Hans Jaeger, Eva Wolf, Christoph D. Spinner

“…The response to supplementation is poorly predictable at an individual level.…”
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Positive hepatitis B surface antigen leads to a decrease in ovarian reserve in infertile patients receiving first in vitro fertilization treatment by Yutao Li, Xuejiao Wang, Ye Jiang, Qun Lv, Yi Zhang, Yu Wang

“…Conclusions HBsAg positivity significantly impairs ovarian reserve in women, but e antigen status does not notably affect it among HBV-infected individuals.…”
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Pleiotropic Associations of RARRES2 Gene Variants and Circulating Chemerin Levels: Potential Roles of Chemerin Involved in the Metabolic and Inflammation-Related Diseases by Leay-Kiaw Er, Semon Wu, Lung-An Hsu, Ming-Sheng Teng, Yu-Ching Sun, Yu-Lin Ko

“…We analyzed the determinants and correlates of retinoic acid receptor responder 2 (RARRES2; encoding chemerin) gene variants and chemerin levels in the Taiwanese population. In total, 612 individuals were recruited. Clinical and metabolic phenotypes, 13 inflammatory markers, 5 adipokines, and 6 single-nucleotide polymorphisms (SNPs) covering the RARRES2 region were analyzed. …”
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Malaria exposure remodels the plasma proteome of Ghanaian children by Aisha M. Mohammed, Charles Ochieng’ Olwal, Andrea Fossati, Nancy K. Nyakoe, Jacqueline M. Fabius, Martin Gordon, Benjamin J. Polacco, Danielle L. Swaney, Gordon A. Awandare, Nevan J. Krogan, Mehdi Bouhaddou, Yaw Bediako

“…Although the lack of an effective vaccine has hindered malaria elimination, studies have reported on individuals acquiring natural immunity to malaria in the context of high malaria exposure. …”
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TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosis by Jin Li, Ling Bai, Zhaodan Xin, Jiajia Song, Hao Chen, Xingbo Song, Juan Zhou

“…Our findings indicate that these mutations are more prevalent in male patients (100% for TERTpm, 83.33% for TP53m), in those with solitary tumors (87.5% for both), in individuals with G2-G3 hepatitis (100% / 83.3%), and in cases of moderately differentiated tumors (75.0% / 83.3%). …”
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Comparison of Atrial Fibrillation in the Young versus That in the Elderly: A Review by Rajiv Sankaranarayanan, Graeme Kirkwood, Katharine Dibb, Clifford J. Garratt

“…The disease itself is extremely heterogeneous in its epidemiology, pathophysiology, and treatment options based on individual patient characteristics. Whilst ageing is well recognised to be an independent risk factor for the development of AF, this condition also affects the young in whom the condition is frequently symptomatic and troublesome. …”
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Comparison of Attenuated Total Reflectance Mid-Infrared, Near Infrared, and 1H-Nuclear Magnetic Resonance Spectroscopies for the Determination of Coffee’s Geographical Origin by Jessica Medina, Diana Caro Rodríguez, Victoria A. Arana, Andrés Bernal, Pierre Esseiva, Julien Wist

“…Although a body of work exists that reports on their individual performances, a faithful comparison has not been established yet. …”
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Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma by Min He, Eduard van Wijk, Ruud Berger, Mei Wang, Katrin Strassburg, Johannes C. Schoeman, Rob J. Vreeken, Herman van Wietmarschen, Amy C. Harms, Masaki Kobayashi, Thomas Hankemeier, Jan van der Greef

“…Oxylipin metabolites were extracted from plasma for each individual sample using solid phase extraction (SPE) and were detected with high performance liquid chromatography/tandem mass spectrometry (HPLC-ESI-MS/MS), using dynamic multiple reaction monitoring (dMRM). …”
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Expanding Thermal Plasma Chemical Vapour Deposition of ZnO:Al Layers for CIGS Solar Cells by K. Sharma, B. L. Williams, A. Mittal, H. C. M. Knoops, B. J. Kniknie, N. J. Bakker, W. M. M. Kessels, R. E. I. Schropp, M. Creatore

“…Whereas such temperature-dependence of CIGS device parameters has previously been linked with chemical migration between individual layers, we demonstrate that in this case it is primarily attributed to the prevalence of shunt currents.…”
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Examining the effect of salbutamol use in ozone air pollution by people with exercise‐induced bronchoconstriction by Bennett T. Stothers, Andy Hung, Patric E. O. Gonçalves, Lulu X. Pei, Tessa van deKerkhof, Jem I. Arnold, Owen D. Harris, Nadine Borduas‐Dedekind, Andrew W. Sheel, Michael S. Koehle

“…We found that salbutamol improved pulmonary function in individuals with EIB when exercising in ozone and did not increase eosinophilic airway inflammation as indicated by FeNO. …”
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Piloting an automated query and scoring system to facilitate APDS patient identification from health systems by Amy M. FitzPatrick, Aaron T. Chin, Sharon Nirenberg, Charlotte Cunningham-Rundles, Keith Sacco, Jesse Perlmutter, Joseph F. Dasso, Athanasios Tsalatsanis, Jay Maru, Jessica Creech, Jolan E. Walter, Nicholas Hartog, Neema Izadi, Mandy Palmucci, Manish J. Butte, Klaus Loewy, Anurag Relan, Nicholas L. Rider

“…The query calculated an “APDS Score,” which stratified risk for APDS for all individuals in these systems. Scores for all known patients with APDS (n=46) were compared.ResultsThe query identified all but one known patient with APDS (98%; 45/46) as well as patients with other complex disease. …”
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Investigating neutropenic enterocolitis: a systematic review of case reports and clinical insights by Samane Nematolahi, Ali Amanati, Hossein Molavi Vardanjani, Mohammadreza Pourali, Mahnaz Hosseini Bensenjan, Farnoosh Nozari, Mohebat Vali, Seyed Reza Abdipour Mehrian, Seyed Ali Nabavizadeh, Farima Safari

“…It is characterized by inflammation and necrosis of the bowel, and most commonly affects the cecum and ascending colon. Although individual case reports have described the features of NE, a comprehensive synthesis of all the published cases is required. …”
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Strengthening the Personnel Potential of Authorities in Ukraine As a Guarantee of Sustainable Development of Society by Yana Kachan, Mariia Masyk, Natalya Balashova, Denys Krasivskiy, Andrii Ivanov

“…The work assessed the state and prospects of achieving the goals of sustainable development; indicators characterizing its condition in terms of individual components were provided. It was shown that, due to the onset of a full-scale invasion and the consequences of the COVID-19 crisis, Ukraine has some difficulties in providing opportunities for economic, environmental and social development. …”
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Informatics strategies for early detection and risk mitigation in pancreatic cancer patients by Di Jin, Najeeb Ullah Khan, Wei Gu, Huijun Lei, Ajay Goel, Tianhui Chen

“…This review underscores the importance of universal genetic testing and the integration of AI with traditional diagnostic methods to improve outcomes in high-risk individuals. Additionally, this review points to future directions in PC diagnostics, including next-generation imaging, molecular biomarkers, and personalized medicine, aiming to overcome current diagnostic challenges and improve survival rates. …”
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Safety profiles of sevoflurane in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database by Chuang Yang, Bangjian Deng, Qiang Wen, Pei Guo, Xiang Liu, Chen Wang

“…We analyzed reports where sevoflurane was the primary suspect in individuals aged 0–18, employing disproportionality analysis to detect adverse events associated with sevoflurane. …”
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Place attachment, activation of personal norms, and the role of emotions to save water in scarcity by Peyman Arjomandi A., Masoud Yazdanpanah, Tahereh Zobeidi, Nadejda Komendantova, Akbar Shirzad

“…This needs accountable actions by both institutions and individuals, contributing to the agricultural dynamism. …”
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