A Novel CRYBB2 Stopgain Mutation Causing Congenital Autosomal Dominant Cataract in a Chinese Family by Yu Zhou, Yaru Zhai, Lulin Huang, Bo Gong, Jie Li, Fang Hao, Zhengzheng Wu, Yi Shi, Yin Yang

“…This family included eight unaffected and five affected individuals. After complete ophthalmic examinations, the blood samples of the proband and two available family members were collected. …”
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Autograft dilation after Ross procedure in children and young adults is mitigated by autograft reinforcement: A retrospective MRI study by Raphael Seiler, Robin Stenzel, Viktoria Weixler, Milena Muiznieks, Marina Gürtner, Felix Berger, Titus Kühne, Mi-Young Cho, Joachim Photiadis, Marcus Kelm, Peter Murin

“…Among 307 patients, 132 MRIs were analyzed from 76 individuals, revealing that autograft z-scores increase primarily with time post-procedure (Coef. 0.13; 95% CI:0.051–0.216; P = 0.002). …”
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The Increase of Circulating PD-1- and PD-L1-Expressing Lymphocytes in Endometriosis: Correlation with Clinical and Laboratory Parameters by Monika Walankiewicz, Ewelina Grywalska, Grzegorz Polak, Izabela Korona-Glowniak, Elzbieta Witt, Agata Surdacka, Jan Kotarski, Jacek Rolinski

“…Using flow cytometric analysis, we assessed the differences in the frequencies of PD-1-positive T and B lymphocytes in the study group and healthy individuals. Alteration of the PD-1/PD-L1 axis may contribute to the pathogenesis of endometriosis, as patients with advanced disease are characterized by higher frequencies of PD-1-positive T and B cells. …”
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The Correlations of Disease Activity, Socioeconomic Status, Quality of Life, and Depression/Anxiety in Chinese Patients with Systemic Lupus Erythematosus by Biyu Shen, Wei Tan, Guijuan Feng, Yan He, Jinwei Liu, Weijun Chen, Xiaoqin Huang, Zhanyun Da, Xujuan Xu, Hong Liu, Zhifeng Gu

“…A self-report survey design was administered to 170 SLE patients and 210 healthy individuals using the Self-Rating Anxiety Scale, the Self-Rating Depression Scale, and the Short Form 36 health survey (SF-36). …”
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Effect of the Holiday Season on Weight Gain: A Narrative Review by Rolando G. Díaz-Zavala, María F. Castro-Cantú, Mauro E. Valencia, Gerardo Álvarez-Hernández, Michelle M. Haby, Julián Esparza-Romero

“…The only study found in children did not show an effect on BMI percentile (−0.4%, p>0.05) during this period. Among individuals with obesity who attempt to lose weight, an increase in weight was observed (0.3 to 0.9 kg, significant in some but not in all studies), as well as increase in weight in motivated self-monitoring people (0.4 to 0.6%, p<0.001). …”
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The rapid rise of SARS‐CoV‐2 Omicron subvariants with immune evasion properties: XBB.1.5 and BQ.1.1 subvariants by Danyi Ao, Xuemei He, Weiqi Hong, Xiawei Wei

“…We expounded on the mechanisms underlying mutations and immune escape from neutralizing antibodies from vaccinated or convalescent COVID‐19 individuals and therapeutic monoclonal antibodies (mAbs) and proposed strategies for prevention against BQ.1 and XBB sublineages.…”
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Prospective observational study to evaluate the feasibility of the mobile app for mild cognitive impairment detection and screening by Reo Hamaguchi, Seiji Hongo, Naoto Doi, Hisamitsu Ide, Ryozo Saito, Junji Kishimoto, Nobuhiro Handa, Shigeo Horie

“…A prospective observational study was conducted with 20 participants, including healthy individuals, MCI patients, and those with mild to moderate-severe dementia. …”
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Symmetry-invariant quantum machine learning force fields by Isabel Nha Minh Le, Oriel Kiss, Julian Schuhmacher, Ivano Tavernelli, Francesco Tacchino

“…We find that our invariant quantum learning models outperform their more generic counterparts on individual molecules of growing complexity. Furthermore, we study a water dimer as a minimal example of a system with multiple components, showcasing the versatility of our proposed approach and opening the way towards larger simulations. …”
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How do Spanish consumers perceive different lettuce cultivation systems? Insights from explicit and implicit methods by Juan Diego Torres, Sara R. Jaeger, Patricia Puerta, Amparo Tárrega

“…Further research should include additional perceptions, such as naturalness and freshness, and analyse individual consumer responses to identify further differences among agricultural systems.…”
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Innovative models of healthcare delivery: an umbrella review of reviews by Frances Rapport, Jeffrey Braithwaite, Yvonne Zurynski, Peter D Hibbert, Kate Churruca, Louise A Ellis, Chiara Pomare, Robyn Clay-Williams, Stephanie Best, Janet C Long, Gaston Arnolda, Bróna Nic Giolla Easpaig, Zeyad Mahmoud, Mitchell N Sarkies, Hoa Mi Nguyen, Karen Hutchinson, Gilbert Thomas Knaggs, Katherine Maka, Elizabeth E Austin, Diana Fajardo Pulido, Sarah Hatem, Natalie Roberts, Emilie Francis Auton, Genevieve Dammery, Isabelle Meulenbroeks, Ann Carrigan, Mai-Tran Nguyen

“…Most of the included reviews reported evidence of comparable or improved care.Conclusions A consideration of local infrastructure and individual patient characteristics, such as health literacy, may be critical in determining the suitability of models of care for patients and their implementation in local health systems.Trial registration number 10.17605/OSF.IO/PS6ZU.…”
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Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo by Marjan Nokhbehsaim, Anna Damanaki, Andressa Vilas Boas Nogueira, Sigrun Eick, Svenja Memmert, Xiaoyan Zhou, Shanika Nanayakkara, Werner Götz, Joni Augusto Cirelli, Andreas Jäger, James Deschner

“…The GHS-R1a expression in human periodontal cells challenged with the periodontopathogen Fusobacterium nucleatum, in gingival biopsies from periodontally healthy and diseased individuals, and from rats with and without ligature-induced periodontitis was analyzed by real-time PCR, immunocytochemistry, and immunofluorescence. …”
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The challenge of a late diagnosis of Autism Spectrum Disorder: co-occurring trajectories and camouflage tendencies. a case report of a young Autistic female with Avoidant Restricti... by Sara Passarini, Sara Passarini, Silvia Guerrera, Maria Picilli, Maria Picilli, Elisa Fucà, Laura Casula, Deny Menghini, Sabine Pirchio, Valeria Zanna, Giovanni Valeri, Stefano Vicari, Stefano Vicari

“…IntroductionAutistic individuals may show several psychiatric co-occurrences, including Feeding and Eating Disorders (FEDs). …”
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Flexibility of Older Adults Aged 55–86 Years and the Influence of Physical Activity by Liza Stathokostas, Matthew W. McDonald, Robert M. D. Little, Donald H. Paterson

“…Shoulder abduction and hip flexion flexibility measurements were obtained from 436 individuals (205 men, 71±9 years; 231 women, 72±8 years). …”
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Evaluation of Gingival Microleakage in Class II Composite Restorations with Different Lining Techniques: An In Vitro Study by Vedavathi Bore Gowda, B. V. Sreenivasa Murthy, Swaroop Hegde, Swapna Devarasanahalli Venkataramanaswamy, Veena Suresh Pai, Rashmi Krishna

“…The mean leakage scores of the individual study groups were Group 1 (33.40), Group 2 (7.85), Group 3 (16.40), and Group 4 (24.35). …”
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Cannabinoid Receptor 1 Gene Polymorphisms and Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and in Healthy Controls by Justyna Kuliczkowska Plaksej, Lukasz Laczmanski, Andrzej Milewicz, A. Lenarcik-Kabza, Anna Trzmiel-Bira, Urszula Zaleska-Dorobisz, Felicja Lwow, Lidia Hirnle

“…Polymorphism of the cannabinoid receptor 1 gene (CNR1) may be responsible for individual susceptibility to obesity and related conditions. …”
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Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules by João Victor Marcelino de Souza, Natalia C. S. Costa, Maria C. O. Arruda Brasil, Luana Ribeiro dos Anjos, Renata Priscila Barros de Menezes, Eduardo Henrique Zampieri, Jhonatan Santos de Lima, Angela Maria Arenas Velasquez, Luciana Scotti, Marcus Tullius Scotti, Marcia A. S. Graminha, Eduardo R. Pérez Gonzalez, Eduardo Maffud Cilli

“…In addition, the bioconjugate was more active against the intracellular enzyme CPP than the individual compounds. This target is very important for the viability and virulence of the parasite within the host cell. …”
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Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells by Zorka Milićević, Vladan Bajić, Lada Živković, Jelena Kasapović, Uroš Andjelković, Biljana Spremo-Potparević

“…The isoforms expressed also varied between individual tumors, indicating potential roles of these p53 variants in human breast cancer.…”
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Probabilistic assessment of the cumulative risk from dietary heavy metal exposure in Chongqing, China using a hazard-driven approach by Jiahui Chen, Jingrong Chen, Mintao Li, Ping Feng, Mei Qin, Ting Chen, Shuquan Luo, Jian Zhao, Xiaofeng Yan, Jinyao Chen, Xuemei Lian, Huadong Zhang, Jiao Huo

“…The results indicated that combined dietary exposure to Pb, Cd, As, and Hg may pose risks of neurotoxicity and nephrotoxicity, with the combined exposure likely amplifying this risk compared to exposure to individual heavy metal elements. mRPI proves to be a more suitable index for cumulative risk assessment using a hazard-driven approach compared to other indexes, as it is derived based on specific studies and endpoints.…”
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Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries by Prashin Unadkat, Tania Rebeiz, Erum Ajmal, Vincent De Souza, Angela Xia, Julia Jinu, Keren Powell, Chunyan Li

“…Furthermore, it underscores significant gaps, particularly the inadequate consideration of interactions among causal factors, environmental influences, and individual susceptibilities. By addressing these gaps, this review provides new insights and calls for a paradigm shift toward a more context-specific and integrative approach to developing targeted therapies for psychological dysfunction following brain injuries.…”
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Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India by S. Sinha, H. Ahmad, R. C. Shekhar, N. Kumar, L. Dar, J. C. Samantaray, S. K. Sharma, A. Bhargava, R. M. Pandey, R. L. Mitsuyasu, J. L. Fahey

“…Our study shows that primary HIVDR mutations have a prevalence of 2.9% among ART-naive chronic HIV-1 infected individuals.…”
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