Rationale and design of a prospective study evaluating population pharmacokinetics and pharmacodynamics of rivaroxaban in Chinese patients with non-valvular atrial fibrillation by Ming-Ming Yan, Xiao-Qin Liu, Yu-Fei Zhang, Hong-Yan Ding, Ming-Kang Zhong, Chun-Lai Ma

“…Introduction Rivaroxaban is one of the most commonly used non-vitamin K antagonists for stroke prevention in patients with non-valvular atrial fibrillation (NVAF). Different individual exposures exist for Asian and non-Asian populations, and dose selection is different for Japanese and non-Japanese subjects. …”
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Historical-pedagogical perspective of intellectual disability across the world and in Serbia by Đurić Zdravković Aleksandra A.

“…He developed a stimulating program for individuals with intellectual disabilities and actively participated in the creation of international associations dedicated to intellectual and developmental disorders, which continue to address these issues today. …”
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Optimal frequency bands for pupillography for maximal correlation with HRV by Júlio Medeiros, André Bernardes, Ricardo Couceiro, Paulo Oliveira, Henrique Madeira, César Teixeira, Paulo Carvalho

“…Correlation analysis yielded a geometric mean of 0.238 compared to Heart Rate Variability features, with individual correlations for low-frequency, high-frequency, and their ratio at 0.279, 0.168, and 0.286, respectively. …”
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Growth response of Douglas fir to the first early and delayed thinning by Dušek David, Novák Jiří

“…At this stage, it is possible to positively influence diameter growth and mitigate the deterioration of individual tree stability as well as the stability of the whole stand.…”
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The COVID-19 Pandemic in the Social Teaching of the Roman Catholic Church by H. T. Sardaryan

“…These questions lead to a revision of the traditional axiology of Western society, based on the primacy of individualism and the atomization of society – approaches that the Roman Catholic Church has traditionally opposed, which in its doctrine is based on the concept of the common good. …”
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Efficacy of BNT162b2 and CoronaVac in patients diagnosed with COVID-19 by Dogan Mustafa, Yilmaz Berna

“…Besides, the reduction in mortality rate was more evident in individuals vaccinated with at least 2 doses of the BNT162b2 (Pfizer-BioNTech) vaccine than in CoronaVac group.…”
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Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome by Aiden M. C. Pike, Saeed Amal, Melissa S. Maginnis, Michael P. Wilczek

“…However, JCPyV can reactivate in immunocompromised individuals and cause progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease with no approved treatment. …”
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Predicting the shield effectiveness of carbon fiber reinforced mortars utilizing metaheuristic algorithms by Mana Alyami, Irfan Ullah, Furqan Ahmad, Hisham Alabduljabbar

“…This study adopts a novel approach by utilizing hybrid models, which offer greater accuracy than individual or ensemble ML models. Specifically, support vector regression (SVR) was combined with three optimization algorithms: firefly algorithm (FFA), particle swarm optimization (PSO), and grey wolf optimization (GWO) to create hybrid models for estimating the SE of carbon fiber-reinforced mortars. …”
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Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study by Mengye Zhang, Hao Lin, Xue Xu

“…Subgroup analysis further revealed a stronger correlation between MQI and IR among individuals with obesity. ROC analysis showed that compared with skeletal muscle and grip strength, MQI (AUC = 0.679 for IR and 0.688 for T2DM) can serve as a more reliable identification factor for IR and T2DM. …”
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Characteristics of transcriptome and chromatin accessibility in the peripheral blood after acute hypoxia exposure by Kuo Zeng, Pei-ru Yuan, Jin-feng Xuan, Lai-xi Zhao, Xiao-na Li, Jun Yao, Dong Zhao

“…Results Hence, we performed RNA sequencing (RNA-seq) and ATAC sequencing (ATAC-seq) to observe the changes of transcriptome and chromatin accessibility in the peripheral blood of eight individuals at 1 h post adaptation in a simulated plateau environment with 3500 m and 4500 m altitude, respectively. …”
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Novel proteomics-based plasma test for early detection of multiple cancers in the general population by Ashkan Afshin, Mohammad H Forouzanfar, Bogdan Budnik, Hossein Amirkhani

“…This study aimed to develop a novel proteome-based multi-cancer screening test that can detect early-stage cancers with high accuracy.Methods and analysis We collected plasma samples from 440 individuals, healthy and diagnosed with 18 early-stage solid tumours. …”
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Ischemic Colitis after Colonoscopy with Bisacodyl Bowel Preparation: A Report of Two Cases by Chris Shamatutu, Daljeet Chahal, Isabella T. Tai, Peter Kwan

“…Our review found that of these cases, there exists significant heterogeneity within individual patient characteristics. The majority of the cases are managed conservatively without complications or sequela. …”
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Genotyping of hexaploid wheat varieties from different Russian regions by I. G. Adonina, I. N. Leonova, E. D. Badaeva, E. A. Salina

“…Comparative analysis of individual dendrograms constructed using 1–2 markers per chromosome, and with the involvement of a larger number of 5B-chromosome markers allowed us to identify varieties with rearrangements of this chromosome and to assess genetic diversity. …”
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Mouse Model of Lipopolysaccharide (LPS)-Induced Pulpitis by Lanting Shao, Baian Chen, Ying Zheng

“…However, the causes of pulpitis vary considerably among individuals, hindering effective research. In this study, we established a mouse model of pulpitis by accessing the pulp cavity, exposing the pulp to lipopolysaccharide (LPS), and then filling the tooth. …”
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Assessing Willingness to Pay for IVF Among Infertile Women in Greece: A Single‐Center Case Study by Christos Ntais, Mary Artsita, Michael A. Talias, John Fanourgiakis, Nikolaos Kontodimopoulos

“…By incorporating this aspect into pricing and policy decisions, Greece can improve the accessibility of IVF services and ensure equitable treatment opportunities for all concerned individuals.…”
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Diverse Molecular Genotypes of Mycobacterium tuberculosis Complex Isolates Circulating in the Free State, South Africa by Anneke Van der Spoel van Dijk, Pakiso M. Makhoahle, Leen Rigouts, Kamaldeen Baba

“…In total, LAM (28 isolates) and T (27 isolates) cause 63% of the individual cases of MTB in our study. The Free State has a highly diverse TB population with LAM being predominant. …”
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Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells by Jingjing Liang, Biao Chen, Yanmei Li, Daibang Nie, Changbin Lei, Qing Yang, Yiqin Zhou, Shenglong Li, Shuaizhi Chen, Bin Li, Lin Shu, Liaobin Chen, Wang Wang

“…Emerging clinical findings has evidenced remarkable tendon damage in individuals with longstanding asymptomatic hyperuricemia, yet the impact of hyperuricemia on tendon homeostasis and associated repercussions is largely unknown. …”
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Justification of Body Mass Index cutoffs for hip and knee joint arthroplasty among California orthopedic surgeons by Sophie V. Orr, Gavin C. Pereira, Blaine A. Christiansen

“…This will help reduce healthcare disparities while also identifying clinical facilities, equipment, training, and procedures that require improvements to accommodate larger individuals. Methods Orthopaedic surgeons were surveyed to identify surgeon-specific BMI cutoffs for hip and knee arthroplasty. …”
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Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program by Salim M. Yakdan, Maya Herrera, Nour Wehbe, Monifa Al Akoum, Muhammad Irfan Kaleem, Miguel A. Ruiz-Cardozo, Karan Joseph, Nada Assaf, Hani Dimassi

“…Logistic regression model for each outcome based on individual characteristics was developed. Results: A total of 2109 patients were included. …”
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Digital Sovereignty in times of AI: between perils of hegemonic agendas and possibilities of alternative approaches by Alexandre Costa-Barbosa, Bianca Herlo, Gesche Joost

“…Predominant perspectives often focus on state, market, or individual sovereignty over data, algorithms, and AI models. …”
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