The Role of PCNA Posttranslational Modifications in Translesion Synthesis by Montaser Shaheen, Ilanchezhian Shanmugam, Robert Hromas

“…Multiple mechanisms have evolved to deal with the individual DNA lesions. Translesion synthesis is a special pathway that enables the replication fork to bypass blocking lesions. …”
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Revitalising strong cultural connections and resilience: Co-designing a pilot Elder-led mentorship program for Indigenous mothers in a remote northern community in Alberta, Canada by Stephanie Montesanti, Kayla M. Fitzpatrick, Barbara S.E. Verstraeten, Beverly Tourangeau, Lorraine Albert, Richard T. Oster

“…Sharing circles with Elders and individual debriefings with mothers were conducted to understand their experiences in the workshops. …”
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Prevalence and Severity of Dental Attrition in a Sample of Kurdish Patients in Erbil City by Rebaz Samir Ismail, Lana Burhan Ali, Reem Zeyad Naja, Iman Haider Mustafa, Anas Jamal Rashid, Trifa Sardar Adnan, Rupak Othman Saad, Yousif Hawar Mawlood

“…To sum up, this study proves that older individuals had more severe attrition affecting both enamel and dentine, while younger ones predominantly showed enamel-only attrition. …”
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Diet-Induced Obesity Is Associated with an Impaired NK Cell Function and an Increased Colon Cancer Incidence by Ina Bähr, Vincent Goritz, Henriette Doberstein, Grit Gesine Ruth Hiller, Philip Rosenstock, Janine Jahn, Ole Pörtner, Tobias Berreis, Thomas Mueller, Julia Spielmann, Heike Kielstein

“…Previous studies showed altered Natural killer (NK) cell functions in obese individuals. Therefore, we studied the impact of an impaired NK cell functionality on the increased colon cancer risk in obesity. …”
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Refining the Make My Day stroke prevention intervention for primary healthcare through co-creation with stakeholders by Cecilia Johnsson, Elin Jakobsson, Maria Hagströmer, Susanne Guidetti, Ann-Helen Patomella, Eric Asaba

“…The process underscored the need to augment a sense of material ownership and to improve interprofessional collaboration in primary healthcare, ultimately enhancing the intervention experience and facilitating the change process for individuals at risk of stroke. Utelising a co-creation process in this current intervention allowed for creation of refinements to the intervention optimising conditions for implementation.…”
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Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome by Roozbeh Khosravi, Khady Ka, Ting Huang, Saeed Khalili, Bich Hong Nguyen, Belinda Nicolau, Simon D. Tran

“…Obesity is also part of a group of risk factors occurring together in an individual, which is referred to as metabolic syndrome. …”
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Prevalence of the oral pathogen Filifactor alocis and its FtxA toxin related to clinical parameters and presence of Aggregatibacter actinomycetemcomitans by Zeinab Razooqi, Nabil Khzam, Nabil Khzam, Mahina L’Hostis, Georgios N. Belibasakis, Anders Johansson, Jan Oscarsson

“…Moreover, among the individuals carrying A. actinomycetemcomitans, a majority also exhibited an ftxA-positive F. alocis, supporting the notion of the synergistic behavior of these two species. …”
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Behavioral and Neural Changes Induced by a Blended Essential Oil on Human Selective Attention by Jieqiong Liu, Shi Cai, Danni Chen, Ke Wu, Yang Liu, Ruqian Zhang, Mei Chen, Xianchun Li

“…Behavioral results showed that individuals responded more quickly in the negative priming condition when exposed to the blended essential oil. …”
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Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy by Ruijing Zhang, Runze Chang, Heng Wang, Jinshan Chen, Chuanlong Lu, Keyi Fan, Yuhang Zhang, Lizheng Li, Sheng Yan, Honglin Dong

“…The serum of 10 patients who were diagnosed with DN and 10 healthy individuals via untargeted metabolomics and Olink proteomics. …”
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Evaluation of the effect of physical-environmental factors of public spaces on the mental health of citizens (Case study: Ardabil city) by Elmira Azimi, Dariush Sattarzadeh, Lida Bolillan, Akbar Abdollahzadeh Tarf, Mahsa Faramarzi Asli

“…Meanwhile, the health of individuals in society as human capital is important in advancing the goals of thematic communities. …”
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Body Image Disturbances Have Impact on the Sexual Problems in Chinese Systemic Lupus Erythematosus Patients by Biyu Shen, Yan He, Haoyang Chen, Chunmei Zhao, Li Zhu, Yingying Gao, Yunli Ren, Xueqing Wang, Jingwei Liu

“…A self-report survey design was administered to 168 SLE patients and 210 healthy individuals. Our results showed that 86 (55.1%) SLE patients reported impaired relationships with a sexual partner or partners, and 100 (64.1%) patients reported impaired sexual function which were significantly higher than the control group (31.6%, 35.7%, rep.). …”
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Lifestyle Characteristics and Gastroesophageal Reflux Disease: A Population-Based Study in Albania by Lulzim Çela, Bledar Kraja, Kliti Hoti, Ervin Toçi, Herion Muja, Enver Roshi, Genc Burazeri

“…A cross-sectional study, conducted in 2012, included a population-representative sample of 845 individuals (≥18 years) residing in Tirana (345 men, mean age: ; 500 women, mean age: ; response rate: 84.5%). …”
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The Effects of Outdoor Source on Pollution Characteristics and Dynamic Changes of Particulate Matter in an Office by Guozhong Zheng, Yuzhen Lu, Yajing Wang, Zhengzheng Zhao, Ke Li, Xutao Zhang

“…The outdoor PM10 concentration levels are divided into the range of 200–300, 300–400, 400–500, 500–600, 600–700 μg·m−3, individually. Firstly, the change characteristics of the mass concentration and the number concentration of the particulate matter in the five outdoor conditions are analyzed. …”
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Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages by S. M. Thomazzi, R. A. Ribeiro, D. I. Campos, F. Q. Cunha, S. H. Ferreira

“…Intraperitoneal injection of a mixture of the recombinants cytokines TNF-α, IL-1 and IL-8 mimicked MNF nociception. The individual injection of these cytokines was unable to induce the nociceptive effect. …”
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Antioxidant Effect of Natural Honeys Affected by Their Source and Origin by Mellen Martin, Fikselová Martina, Mendelová Andrea, Haščík Peter

“…By observing the impact of individual honey samples on antioxidant activity it was found that the sample had a highly statistically significant effect. 10 homogeneous groups which varied in the antioxidant activity among each other were established by all 15 samples. …”
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The Role of Physical Activity in Reducing Endometriosis Pain by Emilia Bąk, Daria Michałka, Natalie Papachristoforou, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Żaneta Góra, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…The effectiveness of exercise in endometriosis therapy depends on the type of exertion, its intensity and frequency, as well as individual factors such as the severity of the disease and the patient's health status. …”
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Sex Differences in Medication and Primary Healthcare Use before and after Spousal Bereavement at Older Ages in Denmark: Nationwide Register Study of over 6000 Bereavements by Anna Oksuzyan, Rune Jacobsen, Karen Glaser, Cecilia Tomassini, James W. Vaupel, Kaare Christensen

“…The study aimed to examine sex differences in healthcare use before and after widowhood to investigate whether reduced healthcare use among widowers compared with widows may partially explain excess mortality and more adverse health outcomes among men than women after spousal loss. Methods. All individuals alive and aged at least 60 years in 1996 and who became widowed in the period from 1996 to 2003 were selected from the 5% sample of the total Danish population and all Danish twins. …”
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Applying in machine learning and deep learning in finance industry: A case study on repayment prediction by Nguyễn Phát Đạt, Hồ Mai Minh Nhật, Trương Công Vinh, Lê Quang Chấn Phong, Lê Hoành Sử

“…This endeavor transcends mere risk mitigation for individual investors, extending to the identification of judicious investment prospects. …”
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The association of gut microbiota, immunocyte dynamics, and protein–protein ratios with tuberculosis susceptibility: a Mendelian randomization analysis by Hanxin Wu, Weijie Ma, Liangyu Zhu, Li Peng, Xun Huang, Lei Zhong, Rui Yang, Bingxue Li, Weijiang Ma, Li Gao, Xinya Wu, Jieqin Song, Suyi Luo, Fukai Bao, Aihua Liu

“…By analyzing the GWAS data of individuals with European ancestry (the FinnGen dataset included 409,568 controls and 2613 cases), using the two-sample MR method, we focused on evaluating the impact of immunocyte-mediated gut microbiota on tuberculosis and the associations between 2821 plasma protein-to-protein ratios and tuberculosis. …”
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Sociodemographic and Behavioral Factors Associated with HIV Vulnerability according to Sexual Orientation by Maria Aparecida A. O. Serra, Antoninho B. Milhomem, Samae B. Oliveira, Francisca Aline A. S. Santos, Roberta Araújo e Silva, Ana Cristina P. J. Costa, Maria da Conceição S. O. Cunha, Antônio Uelton A. Silva, Roberto Wagner J. F. Freitas, Márcio Flávio M. Araújo

“…A substantial portion of the sample stated they were heterosexual (88.8%). These individuals demonstrated a lower chance of HIV infection (p<0.001), sexually transmitted infections (p<0.001), alcohol use (p<0.001) and condom use (p<0.001), compared to men who have sex with men and/or bisexuals. …”
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