Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

“…Its adoption by local administrative organizations could provide ongoing support, offering a scalable solution for improving the care of bedridden individuals both in Thailand and globally.Keywords: the KKU Bedridden Care Model, community caregivers, family caregivers, stroke survivors, long-term care, Northeastern Thailand…”
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Estimation of cause-specific mortality in Rakai, Uganda, using verbal autopsy 1999-2019 by Dorean Nabukalu, Júlia Almeida Calazans, Milly Marston, Clara Calvert, Hadijja Nakawooya, Brendah Nansereko, Robert Sekubugu, Gertrude Nakigozi, David Serwadda, Nelson Sewankambo, Godfrey Kigozi, Ronald H Gray, Fred Nalugoda, Fredrick Makumbi, Tom Lutalo, Jim Todd

“…The average number of years lived in adulthood increased in people living with HIV and decreased in HIV-negative individuals between 2000 and 2019. Communicable diseases, primarily HIV and Malaria, had the biggest decreases, which improved the average number of years lived by approximately extra 12 years of life in females and 6 years in males. …”
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Protective factors for suicidal ideation and suicide attempts in adolescence: a longitudinal population-based cohort study examining sex differences by Victoria Bakken, Stian Lydersen, Norbert Skokauskas, Anne Mari Sund, Jannike Kaasbøll

“…Methods This study utilized data from a representative sample at two timepoints, T1 (N = 2464, 50.8% females, mean age = 13.7, SD = 0.6) in 1998 and T2 (N = 2432, 50.4% females, mean age = 14.9, SD = 0.6) one year later, collected as part of the longitudinal Youth and Mental Health Study (YAMHS) in Norway. Individual, social and environmental protective factors were identified based on prior research and theoretical frameworks. …”
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Is surgery superior for distal ulna fractures? a comprehensive systematic review and meta-analysis by Zakaria Chabihi, Brahim Demnati, Mohamed Moussadiq, Tariq Aalil, Yassine Fath El Khir, El Mehdi Boumediane, Mohamed Amine Benhima, Imad Abkari

“…Conclusions While surgical management may offer a higher union rate, the choice of treatment should be individualized, balancing the potential benefits against the risks of surgery, as ORIF implants are typically associated with higher ulnar-sided pain rates and limited ulnar deviation due to implant prominence. …”
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Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

“…However, Pilates exercise during pregnancy was associated with significant improvements in APGAR scores at 1 min (SMD 0.41; 95% CI, 0.08 to 0.74; P = 0.015), a reduction in the duration of labor (SMD − 0.557; 95% CI, -0.915 to -0.198; P = 0.002), and a decrease in the Visual Analogue Score (VAS) score (SMD − 0.76; 95% CI, -1.45 to -0.07; P = 0.032). (3) Sensitivity analysis revealed no significant differences in effect size before and after the removal of any individual study, indicating that the meta-analysis results were stable. …”
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Exploring the landscape of entrepreneurship in Pakistan: a comparative analysis of perceptions, challenges, and the need for psychoeducational interventions in the academic sector by Khurram Mehboob, Muhammad Ali, Noor Hassan, Zeeshan Mehboob, Muhammad Faisal Mushtaq, Rana Hamad Ullah, Muhammad Zahid Akhtar, Muhammad Akram Tariq, Khalida Parveen, Riffat Mehboob

“…It also sought to evaluate the barriers and motivational factors promoting entrepreneurship among these universities.MethodsA cross-sectional study was conducted, and a comprehensive questionnaire was utilized to collect data. A total of 213 individuals from different disciplines took part in the study. …”
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Technology Readiness Level and Self-Reported Health in Recipients of an Implantable Cardioverter Defibrillator: Cross-Sectional Study by Natasha Rosenmeier, David Busk, Camilla Dichman, Kim Mechta Nielsen, Lars Kayser, Mette Kirstine Wagner

“…This aims to enhance health care professionals’ understanding of different patient archetypes, serving as guidance in delivering personalized services tailored to the needs, resources, and capabilities of individual recipients of ICDs. MethodsOverall, 79 recipients of an ICD participated in a survey assessing technology readiness using the READHY. …”
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Mortality trends of traumatic brain injuries in the adult population of the United States: a CDC WONDER analysis from 1999 to 2020 by Muhammad Hamza Dawood, Yusra Fazli, Sejal Lund, Shurjeel Uddin Qazi, Rija Tahir, Areehah Zafar Masood, Aiman Azam Qureshi, Saleha Safdar, Heraa Zaheer, Muhammad TayyabMuzaffar Chaychi

“…Age-adjusted mortality rates (AAMRs) per 100,000 individuals and annual percent change (APC) were computed and stratified based on year, gender, race/ethnicity, and geographic region. …”
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iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis by Jingyu Zhao, Jingyu Zhao, Wei Fang, Yangjie Gao, Jiquan Chen, Guizhen Wang, Julin Gu

“…BackgroundCryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. Amphotericin B (AmB) serves as the cornerstone treatment for CM; however, its clinical application is restricted due to limited penetration of the blood–brain barrier and associated nephrotoxicity.ObjectiveThis study investigates the use of exosomes derived from induced pluripotent stem cells (iPSC-Exos) as carriers for AmB in treating CM, aiming to enhance therapeutic efficacy and safety and reduce AmB toxicity.MethodsExosomes were extracted from iPSC culture supernatants using ultrafiltration and ultracentrifugation. …”
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A Framework for Analyzing Absorptive Capacity Using Social Network Analysis (Case Study: Sharif University Innovation Ecosystem) by Mahdi Mohammadi, Mahdi Elyasi, Azadeh Savehshemshaki

“…Although the analysis of absorptive capacity has traditionally focused on individual companies without considering the geographical context and external knowledge connections, this approach has often overlooked the external role of companies. …”
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The role of gut microbiota in disease management: Ayurvedic perspectives on metabolic diseases and health by Bhawana Jangra, Shreyanshi Kulshreshtha, Alok Goyal, Sanjay M. Jachak

“…These have direct or indirect effects on an individual's health and diseases, viz. dysbiosis, UC, IBD, cardio-vascular diseases, chronic kidney disorders, etc. …”
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Impact of obesity, overweight and underweight on life expectancy and lifetime medical expenditures: the Ohsaki Cohort Study by Shinichi Kuriyama, Miyuki Kawado, Shuji Hashimoto, Ichiro Tsuji, Atsushi Hozawa, Toshimasa Sone, Masato Nagai, Masako Kakizaki, Kaori Ohmori-Matsuda

“…We examined the association between body mass index, life expectancy and lifetime medical expenditure.Design Prospective cohort study using individual data from the Ohsaki Cohort Study.Setting Miyagi Prefecture, northeastern Japan.Participants The 41 965 participants aged 40–79 years.Primary and secondary outcome measures The life expectancy and lifetime medical expenditure aged from 40 years.Results In spite of their shorter life expectancy, obese participants might require higher medical expenditure than normal weight participants. …”
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Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…Based on the analysis of the dose-effect relationship, the optimal clinically effective dose of prednisolone for patients with UC and CD during the first induction course was established, equal to 0.70 mg/kg, which can be recommended for use in clinical practice for calculating individual doses.…”
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Investigating the Feasibility of Behavioral Nudges to Reduce the Phenomenon of Escape from Responsibility in Public Sector by Seyed Kamal Vaezi, Mahboubeh Hosseini

“…The field of behavioral sciences offers a wide range of nudge interventions that can be implemented at both individual and organizational levels. Therefore, this article attempts to redefine the concept of escape from responsibility in executive systems considering the administrative environment. …”
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Just-In-Time Adaptive Interventions to Promote Behavioral Health: Protocol for a Systematic Review by Lauren M Henry, Morkeh Blay-Tofey, Clara E Haeffner, Cassandra N Raymond, Elizabeth Tandilashvili, Nancy Terry, Miryam Kiderman, Olivia Metcalf, Melissa A Brotman, Silvia Lopez-Guzman

“… BackgroundThe goal of just-in-time adaptive interventions (JITAIs) is to use mobile, digital tools to provide individuals with personalized interventions at the optimal time and in the optimal context. …”
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Functional Evaluation of Open Carpal Tunnel Release in Carpal Tunnel Syndrome Patients by Swagat Mahapatra, Devta Singh, Prakhar Mishra, Jaydeep Patel, Madhusudan Mishra, Animesh Gupta

“…Carpal tunnel syndrome is a musculoskeletal disorder related to work activity in affected individuals that is caused by strain and repetitive activity, making it a very common problem across manual laborers. …”
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Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity by Eamonn MM Quigley, Thomas J Borody, Sabine Hazan, Neil Stollman, Huseyin S Bozkurt, Sonya Dave, Andreas J Papoutsis, Jordan Daniels, Brad D Barrows

“…Exposed controls were individuals with prolonged or repeated close contact with patients with SARS-CoV-2 infection or their samples, for example, household members of patients or frontline healthcare workers. …”
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Virulence factor discovery identifies associations between the Fic gene family and Fap2+ fusobacteria in colorectal cancer microbiomes by Geicho Nakatsu, Duhyun Ko, Monia Michaud, Eric A. Franzosa, Xochitl C. Morgan, Curtis Huttenhower, Wendy S. Garrett

“…Using a global data set of CRC shotgun metagenomes, we show that fusobacterial Fic and Fap2 genes frequently co-occur in the fecal microbiomes of individuals with late-stage CRC. We further characterize specific Fic gene families harbored by Fap2+ Fusobacterium animalis genomes and detect recombination events and elements of horizontal gene transfer via synteny analysis of Fic gene loci. …”
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“Unmasking the Uncommon”: A case series of multi-drug resistant Elizabethkingia meningoseptica causing late-onset sepsis and meningitis in preterm neonates [version 2; peer review:... by Anisha Maria Fernandes, Sinchana Bhat, Suchitra Shenoy M., Prajnha U.P.

“…Elizabethkingia meningoseptica is an uncommon nosocomial pathogen that causes meningitis, pneumonia, and sepsis in neonates and in immunocompromised individuals. It exhibits resistance to many commonly employed first-line antibiotics used to treat gram-negative pathogens. …”
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Prevalence and correlates of symptoms of depression, anxiety, and psychological distress among women of reproductive age with delayed conception in urban and peri-urban low to mid-... by Barsha Gadapani Pathak, Gitau Mburu, Ndema Habib, Rita Kabra, Aiysha Malik, James Kiarie, Ranadip Chowdhury, Neeta Dhabhai, Sarmila Mazumder

“…<h4>Conclusion</h4>This study demonstrates the high mental health burden faced by women with delayed conception in low- to mid-socioeconomic neighbourhoods of North India including high levels of anxiety and depression. To better support individuals and couples achieve their reproductive goals, we advocate for the integration of psychosocial interventions to improve mental health outcomes and promote the well-being of those facing delays in achieving pregnancy. …”
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