The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts by Rafaela Torres Portugal Leite, Sarah de Oliveira Nogueira, João Paulo Rodrigues do Nascimento, Laisa Soares de Lima, Taís Bastos da Nóbrega, Mariana da Silva Virgínio, Lucas Monte da Costa Moreno, Bruno Henrique Barbosa Sampaio, Fábio Gomes de Matos e Souza

“…The first depressive episode was at 18.5 and 24.4 years, respectively. Individuals misusing cannabis showed increased risk of suicide. …”
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Health interventions to promote light physical activity in children and adolescents with physical inactivity – a review of research progress by Siji WANG, Jian LI, Jiu CHEN, Wenlai CUI, Yibing WANG, Zhe KONG, Jun XIE

“…Physical inactivity refers to an individual′s failure to meet the recommended amount of physical activity for their age group as outlined in physical activity guidelines. …”
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Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse by Emine Kalkan Akcay, Murat Akcay, Betul Seher Uysal, Pinar Kosekahya, Abdullah Nabi Aslan, Mehtap Caglayan, Cemal Koseoglu, Fatma Yulek, Nurullah Cagil

“…KC prevalence is higher than control individuals in MVP patients and the biomechanical properties of the cornea are altered in patients with MVP. …”
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Exploring urban–rural inequities in older adults life expectancy: a case study in Zhejiang, China for health equity by Yongguo Chen, Yongguo Chen, Xiaoting Fan, Shusheng Shen, Shusheng Shen, Yong Chen, Yong Chen, Zhiwei Pan, Zixuan Chen, Haoqiang Zhong, Menglong Li

“…This study investigates the inequities in life expectancy among individuals aged 65 and above in urban and rural areas of Zhejiang Province, China, with a primary focus on promoting health equity among the older adults population. …”
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Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration by Nitchaphat Khansakorn, Waranya Wongwit, Prapin Tharnpoophasiam, Bunlue Hengprasith, Lerson Suwannathon, Suwannee Chanprasertyothin, Thunyachai Sura, Sming Kaojarern, Piyamit Sritara, Jintana Sirivarasai

“…No significant differences in blood Cd concentrations among individual with gene deletions of GSTT1 and GSTM1 were observed. …”
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Differential Susceptibility to Particulate Matter-Induced Cardiac Remodeling and Senescence: A Comparative Study in Young and Aged Mice by Dunia Waked, Gabriel Henrique Rodella Guedes, Raissa Macedo, Paulo Hilário Nascimento Saldiva, Mariana Matera Veras, Ana Paula Cremasco Takano

“…Conclusions: Our study indicates that younger individuals may be more vulnerable to the cardiovascular effects of chronic PM than older individuals exposed later. …”
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From Multimorbidity to Network Medicine in Patients with Rheumatic Diseases by Winston Gilcrease, Luca Manfredi, Savino Sciascia, Fulvio Ricceri

“…Multimorbidity expands on the concept of comorbidity by encompassing the presence of multiple diseases, which results in further individual and societal impacts. This approach, while valuable, often leads to fragmented care focused on individual diseases rather than the patient as a whole. …”
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Identification of Interactive Genetic Loci Linked to Insulin Resistance in Metabolic Syndrome—An Update by Imadeldin Elfaki, Rashid Mir, Mohamed E. Elnageeb, Abdullah Hamadi, Zeyad M. Alharbi, Ruqaiah I. Bedaiwi, Jamsheed Javid, Tariq Alrasheed, Dalal Alatawi, Basmah M. Alrohaf, Mohammed K. Abunab, Turki Ahmed Muqri

“…Genetic testing is invaluable in the identification and stratification of susceptible populations and/or individuals. After susceptible individuals and/or populations have been identified via genetic testing or screening, lifestyle modifications such as regular exercise, weight loss, a healthy diet, and smoking cessation can reduce or prevent metabolic syndrome and its associated pathologies.…”
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Application of Handheld Tele-ECG for Health Care Delivery in Rural India by Meenu Singh, Amit Agarwal, Vineet Sinha, Rohit Manoj Kumar, Nishant Jaiswal, Ishita Jindal, Pankaj Pant, Munish Kumar

“…ECG was obtained in 450 individuals (mean age 31.49 ± 20.058) residing in the periphery of Chandigarh, India, from April 2011 to March 2013, using the handheld tele-ECG machine. …”
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Failure to Return for Posttest Counseling and HIV Test Results at the Prevention and Voluntary Testing and Counseling Centers of Douala, Cameroon: An Evaluation of a Routine Five-Y... by Patrice Ngangue, Emmanuelle Bedard, Gerard Ngueta, Dieudonné Adiogo, Marie-Pierre Gagnon

“…HIV testing and counseling services in Douala district hospitals must be reorganized such that individuals tested for HIV receive their results on the same day of the test. …”
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Proteomic Analysis of the Murine Liver Response to Oral Exposure to Aflatoxin B1 and Ochratoxin A: The Protective Role to Bioactive Compounds by Silvia Trombetti, Alessandra Cimbalo, Michela Grosso, Pilar Vila-Donat, Jordi Mañes, Lara Manyes

“…For the experimental procedures, rats were fed AFB1 and OTA individually or in combination, with the addition of FW or a FW-P mixture during 28 days. …”
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Altered Functional Connectivity after Epileptic Seizure Revealed by Scalp EEG by Yi Liang, Chunli Chen, Fali Li, Dezhong Yao, Peng Xu, Liang Yu

“…., characteristic path length and clustering coefficient) and individual seizure number. The PSD, fuzzy entropy, and network analysis may indicate that the brain is gradually impaired along with the occurrence of epilepsy, and the accumulated effect of brain impairment is observed in individuals with consecutive epileptic bursts. …”
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Multifactorial Origin of Exertional Rhabdomyolysis, Recurrent Hematuria, and Episodic Pain in a Service Member with Sickle Cell Trait by Nyamkhishig Sambuughin, Mingqiang Ren, John F. Capacchione, Ognoon Mungunsukh, Kevin Chuang, Iren Horkayne-Szakaly, Francis G. O’Connor, Patricia A. Deuster

“…Individuals with Sickle Cell Trait (SCT), generally considered a benign carrier state of hemoglobin S (HbAS), are thought to be at risk for exertional rhabdomyolysis and hematuria, conditions that can also be caused by various other acquired and inherited factors. …”
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Perceptions of science, science communication, and climate change attitudes in 68 countries – the TISP dataset by Niels G. Mede, Viktoria Cologna, Sebastian Berger, John Besley, Cameron Brick, Marina Joubert, Edward W. Maibach, Sabina Mihelj, Naomi Oreskes, Mike S. Schäfer, Sander van der Linden, Nor Izzatina Abdul Aziz, Suleiman Abdulsalam, Nurulaini Abu Shamsi, Balazs Aczel, Indro Adinugroho, Eleonora Alabrese, Alaa Aldoh, Mark Alfano, Innocent Mbulli Ali, Mohammed Alsobay, Marlene Altenmüller, R. Michael Alvarez, Richard Amoako, Tabitha Amollo, Patrick Ansah, Denisa Apriliawati, Flavio Azevedo, Ani Bajrami, Ronita Bardhan, Keagile Bati, Eri Bertsou, Cornelia Betsch, Apurav Yash Bhatiya, Rahul Bhui, Olga Białobrzeska, Michał Bilewicz, Ayoub Bouguettaya, Katherine Breeden, Amélie Bret, Ondrej Buchel, Pablo Cabrera-Álvarez, Federica Cagnoli, André Calero Valdez, Timothy Callaghan, Rizza Kaye Cases, Sami Çoksan, Gabriela Czarnek, Steven De Peuter, Ramit Debnath, Sylvain Delouvée, Lucia Di Stefano, Celia Díaz-Catalán, Kimberly C. Doell, Simone Dohle, Karen M. Douglas, Charlotte Dries, Dmitrii Dubrov, Małgorzata Dzimińska, Ullrich K. H. Ecker, Christian T. Elbaek, Mahmoud Elsherif, Benjamin Enke, Tom W. Etienne, Matthew Facciani, Antoinette Fage-Butler, Md. Zaki Faisal, Xiaoli Fan, Christina Farhart, Christoph Feldhaus, Marinus Ferreira, Stefan Feuerriegel, Helen Fischer, Jana Freundt, Malte Friese, Simon Fuglsang, Albina Gallyamova, Patricia Garrido-Vásquez, Mauricio E. Garrido Vásquez, Winfred Gatua, Oliver Genschow, Omid Ghasemi, Theofilos Gkinopoulos, Jamie L. Gloor, Ellen Goddard, Mario Gollwitzer, Claudia González-Brambila, Hazel Gordon, Dmitry Grigoryev, Gina M. Grimshaw, Lars Guenther, Håvard Haarstad, Dana Harari, Lelia N. Hawkins, Przemysław Hensel, Alma Cristal Hernández-Mondragón, Atar Herziger, Guanxiong Huang, Markus Huff, Mairéad Hurley, Nygmet Ibadildin, Maho Ishibashi, Mohammad Tarikul Islam, Younes Jeddi, Tao Jin, Charlotte A. Jones, Sebastian Jungkunz, Dominika Jurgiel, Zhangir Kabdulkair, Jo-Ju Kao, Sarah Kavassalis, John R. Kerr, Mariana Kitsa, Tereza Klabíková Rábová, Olivier Klein, Hoyoun Koh, Aki Koivula, Lilian Kojan, Elizaveta Komyaginskaya, Laura König, Lina Koppel, Kochav Koren Nobre Cavalcante, Alexandra Kosachenko, John Kotcher, Laura S. Kranz, Pradeep Krishnan, Silje Kristiansen, André Krouwel, Toon Kuppens, Eleni A. Kyza, Claus Lamm, Anthony Lantian, Aleksandra Lazić, Oscar Lecuona, Jean-Baptiste Légal, Zoe Leviston, Neil Levy, Amanda M. Lindkvist, Grégoire Lits, Andreas Löschel, Alberto López-Ortega, Carlos Lopez-Villavicencio, Nigel Mantou Lou, Chloe H. Lucas, Kristin Lunz-Trujillo, Mathew D. Marques, Sabrina J. Mayer, Ryan McKay, Hugo Mercier, Julia Metag, Taciano L. Milfont, Joanne M. Miller, Panagiotis Mitkidis, Fredy Monge-Rodríguez, Matt Motta, Iryna Mudra, Zarja Muršič, Jennifer Namutebi, Eryn J. Newman, Jonas P. Nitschke, Ntui-Njock Vincent Ntui, Daniel Nwogwugwu, Thomas Ostermann, Tobias Otterbring, Jaime Palmer-Hague, Myrto Pantazi, Philip Pärnamets, Paolo Parra Saiani, Mariola Paruzel-Czachura, Michal Parzuchowski, Yuri G. Pavlov, Adam R. Pearson, Myron A. Penner, Charlotte R. Pennington, Katerina Petkanopoulou, Marija M. Petrović, Jan Pfänder, Dinara Pisareva, Adam Ploszaj, Karolína Poliaková, Ekaterina Pronizius, Katarzyna Pypno-Blajda, Diwa Malaya A. Quiñones, Pekka Räsänen, Adrian Rauchfleisch, Felix G. Rebitschek, Cintia Refojo Seronero, Gabriel Rêgo, James P. Reynolds, Joseph Roche, Simone Rödder, Jan Philipp Röer, Robert M. Ross, Isabelle Ruin, Osvaldo Santos, Ricardo R. Santos, Philipp Schmid, Stefan Schulreich, Bermond Scoggins, Amena Sharaf, Justin Sheria Nfundiko, Emily Shuckburgh, Johan Six, Nevin Solak, Leonhard Späth, Bram Spruyt, Olivier Standaert, Samantha K. Stanley, Gert Storms, Noel Strahm, Stylianos Syropoulos, Barnabas Szaszi, Ewa Szumowska, Mikihito Tanaka, Claudia Teran-Escobar, Boryana Todorova, Abdoul Kafid Toko, Renata Tokrri, Daniel Toribio-Florez, Manos Tsakiris, Michael Tyrala, Özden Melis Uluğ, Ijeoma Chinwe Uzoma, Jochem van Noord, Christiana Varda, Steven Verheyen, Iris Vilares, Madalina Vlasceanu, Andreas von Bubnoff, Iain Walker, Izabela Warwas, Marcel Weber, Tim Weninger, Mareike Westfal, Florian Wintterlin, Adrian Dominik Wojcik, Ziqian Xia, Jinliang Xie, Ewa Zegler-Poleska, Amber Zenklusen, Rolf A. Zwaan

“…Abstract Science is integral to society because it can inform individual, government, corporate, and civil society decision-making on issues such as public health, new technologies or climate change. …”
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Hippocampal Dendritic Spines Are Segregated Depending on Their Actin Polymerization by Nuria Domínguez-Iturza, María Calvo, Marion Benoist, José Antonio Esteban, Miguel Morales

“…Using FRAP, we have reexamined the actin dynamics of individual spines from pyramidal hippocampal neurons, both in cultures and in hippocampal organotypic slices. …”
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A Special Points and Neural Network-Based Dynamic Multi-Objective Optimization Algorithm by Sanyi Li, Wenjie Hou, Peng Liu, Weichao Yue, Qian Wang

“…The convergence variables of special points are locally searched to form a new population and the best individuals of this population are selected. Finally, a portion of the initial population is generated by conducting a local search on the diversity variables of best individuals, while the remaining portion is produced using random strategies. …”
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Patient-derived xenografts from circulating cancer stem cells as a preclinical model for personalized pancreatic cancer research by Benedikt J. Wagner, Andreas Ettner-Sitter, Nicolas A. Ihlo, Merle Behr, Sebastian Koelbl, Stefan M. Brunner, Florian Weber, Bettina M. Rau, Hans J. Schlitt, Christoph Brochhausen, Rebecca Schoenmehl, Annalena Artinger, Dorothea Schott, Monika Pizon, Katharina Pachmann, Thiha Aung, Silke Haerteis, Christina Hackl

“…Hence, this model represents a novel and fast option for individualized testing of new therapies for PDAC.…”
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Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring by Federico Sizzano, Sebastiano Collino, Ornella Cominetti, Daniela Monti, Paolo Garagnani, Rita Ostan, Chiara Pirazzini, Maria Giulia Bacalini, Daniela Mari, Giuseppe Passarino, Claudio Franceschi, Alessio Palini

“…However, little is known about the capability of the immune cells of elderly individuals to dynamically counteract the oxidative stress. …”
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Oxidative Stress and Cytoskeletal Reorganization in Hypertensive Erythrocytes by Ivette Martínez-Vieyra, Isaac Hernández-Rojo, Víctor Hugo Rosales-García, Aracely Evangelina Chávez-Piña, Doris Cerecedo

“…These alterations in protein expression and distribution suggest that oxidative stress in hypertensive individuals may induce structural modifications, ultimately impairing erythrocyte membrane elasticity and function.…”
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Mamba vision models: Automated American sign language recognition by Ali Salem Altaher, Chiron Bang, Bader Alsharif, Ahmed Altaher, Munid Alanazi, Hasan Altaher, Hanqi Zhuang

“…Historically, individuals with hearing impairments have faced significant challenges in effective communication due to the lack of adequate resources. …”
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